Origin
San Mateo, CA
Late night in San Mateo on Tuesday
Local time
3:41 AM
PDT
Current temp
--
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
7h 29m
Distance
394.8 mi
635 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$91
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
San Mateo, CA
Wikimedia Commons
San Mateo, CA to Anaheim, CA is 394.8 miles and takes about 7h 29m via Westside Freeway and I 5 Truck, with a fuel budget near $91 and enough daylight to finish in a day. This drive primarily stays within California, moving from the Pacific Coast region down towards Southern California. It's mostly highway driving, making it a straightforward trip if you're looking to get from point A to point B efficiently. You'll spend the majority of your time on major freeways, so plan for consistent travel speeds. This route is well-suited for a single-day push, especially if you get an early start.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
197.4 miles from San Mateo, CA
A natural place for your longest stop of the day , about 3h 45m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Westside Freeway | 181.1 mi | 3h 14m |
| I 5 Truck | 83.3 mi | 1h 36m |
| Bayshore Freeway | 59.8 mi | 1h 8m |
| Pacheco Pass Highway | 40.6 mi | 50m |
| Santa Ana Freeway | 20.7 mi | 24m |
| Golden State Freeway | 5.3 mi | 6m |
| West Lincoln Avenue | 1.3 mi | 3m |
| East 3rd Avenue | 0.4 mi | <1m |
Step-by-step road directions between San Mateo, CA and Anaheim, CA.
Start on CA 82
Turn right onto East 3rd Avenue
Turn right onto South Delaware Street
Turn left onto East 4th Avenue
Keep slight left at fork onto East 4th Avenue
Take the ramp
Merge onto US 101
Keep slight left at fork onto US 101
Take the exit onto CA 152
Turn left onto CA 152
Continue on CA 152
Take the exit
Merge onto I 5
Keep slight right at fork onto I 5 Truck
Keep slight left at fork onto I 5
Keep slight right at fork onto I 5 Truck
Keep slight left at fork onto I 5 Truck
Keep slight left at fork onto I 5
Merge onto I 5
Take the exit
Turn left onto West Lincoln Avenue
Turn right onto South Anaheim Boulevard
Turn right
Arrive at destination
Given the 7h 29m estimated drive time, departing from San Mateo early in the morning is your best bet to avoid significant traffic. With two recommended stops, you can easily break up the 394.8 miles into manageable segments. Consider making your first stop around the halfway point to refuel and stretch. Since the majority of this trip is on the Westside Freeway and I 5 Truck, keep an eye on your fuel gauge, as services can sometimes be spaced further apart on these longer highway stretches. The $91 fuel cost is an estimate, so checking current prices along your route is always a good idea.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 87 miles or 1h 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 197.4 miles or 3h 45m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 16m
Traffic, exits, and arrival timing usually matter more near Anaheim, CA than in the middle of the route.
Open the route before leaving San Mateo, CA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from San Mateo, CA
This is one driving day of about 394.8 miles and 7h 29m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
197 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 87 miles helps settle the day before fatigue starts building.
The midpoint is around 197.4 miles from San Mateo, CA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Westside Freeway if your tank is already low. That segment runs about 181.1 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 0.5 and 371 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn left onto East 4th Avenue
Lane positioning matters here
Keep slight left at fork onto East 4th Avenue
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight left at fork onto US 101 / Bayshore Freeway toward US 101 South: San Jose, Los Angeles
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork onto I 5 Truck toward I 405 South
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight left at fork onto I 5 / Golden State Freeway toward CA 60 East, I 5 South: Pomona, Soto Street, Santa Ana
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Regular Gas
$90.74 one way
$181.48 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $6.02 | $93.51 | $187.02 |
| premium | $6.18 | $96.01 | $192.02 |
| diesel | $5.61 | $87.17 | $174.33 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$91
Meals
$25–$50
Total
$116–$141
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 138.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $41 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 118.4 | 1 | $41.45 | $18.95 |
| Efficient EV | 98.7 | 1 | $34.55 | $15.79 |
| EV Truck/SUV | 157.9 | 1 | $55.27 | $25.27 |
Gas CO2
138 kg
EV CO2
46 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in San Mateo on Tuesday
Local time
3:41 AM
PDT
Current temp
--
Unavailable
Destination
Late night in Anaheim on Tuesday
Local time
3:41 AM
PDT
Current temp
55°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
This route is predominantly highway, with 89% of the 394.8 miles on major roads like the Westside Freeway and I 5 Truck. The longest continuous stretch you'll encounter is 181.1 miles on the Westside Freeway. After this, you'll transition to surface roads for the remainder of your trip. Expect a significant amount of merging and exiting as you navigate through populated areas.
This is a straightforward highway drive that stays mostly on Westside Freeway and I 5 Truck. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.5 miles in near East 4th Avenue.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 21 significant decision points across 394.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.5 miles (East 4th Avenue): Lane positioning matters here; at 0.7 miles (East 4th Avenue): Highway fork - watch signs carefully. Lane positioning matters here; at 18.4 miles (US 101 / Bayshore Freeway): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from San Mateo, CA to Anaheim, CA, road signs begin pointing toward Santa Ana along the way.
Santa Ana
Founded 1857
Anaheim is a city in Orange County, California. It is best known for being the home of Disneyland. Its second claim to fame is hosting the National Hockey League's Anaheim Ducks and Major League Baseball's Los Angeles Angels.
Top landmarks
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 7h 29m. Total distance: 394.8 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 29m drive, plan rest stops for pacing.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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