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Trip from Saltillo, MS to Tupelo, MS

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

17m

Distance

11.1 mi

18 km

Drive Score

7/10

Good drive

Same Day?

Yes, doable

Fuel Cost

$2

one way

EV Charging

Fair

3 stations

Best Time to Leave

4 AM
0h 16m ★
6 AM
0h 17m
8 AM
0h 20m
10 AM
0h 18m
12 PM
0h 18m
3 PM
0h 18m
5 PM
0h 20m
8 PM
0h 16m ★

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Saltillo, MS, MS

Saltillo, MS

Wikimedia Commons

Downtown Tupelo, MS, MS

Tupelo, MS

Wikimedia Commons

Trip Overview

Traveling between Saltillo and Tupelo is a quick, straightforward 11.1-mile journey that typically takes about 17 minutes to complete. Because of the short distance, this trip is easily managed as a brief day outing rather than an overnight stay. You will primarily navigate via US 45, North 3rd Avenue, and MS 145 while staying within the Southeast region. Budgeting for fuel is incredibly simple, as you will likely spend only about $2 for the entire trip. Whether you are commuting or just crossing between these two Mississippi towns, the route offers a convenient and efficient connection.

Main Roads

Road Distance Duration
US 45 7 mi 8m
North 3rd Avenue 1.2 mi 3m
MS 145 1.2 mi 2m
North Front Street 0.9 mi 1m
East Mobile Street <0.1 mi <1m
West Main Street <0.1 mi <1m
North Spring Street <0.1 mi <1m
Longest stretch: US 45 — 7 mi, about 8m

Turn-by-Turn Driving Directions

Step-by-step road directions between Saltillo, MS and Tupelo, MS.

1

Start on MS 363

500 ft · 12 sec · East Mobile Street
2

Turn right onto MS 766

1.2 mi · 3 min · North 3rd Avenue
3

Turn sharp left onto MS 145

1.2 mi · 2 min · MS 145
4

Take the ramp

0.3 mi · 35 sec
Toward Tupelo
5

Merge onto US 45

7.0 mi · 8 min · US 45
Use the straight / slight right lanes.
6

Take the exit

0.3 mi · 35 sec
Toward Downtown Tupelo Use the straight / slight right lanes.
7

Continue on North Front Street

0.9 mi · 1 min · North Front Street
Use the straight / left lanes.
8

Turn right onto West Main Street

322 ft · 13 sec · West Main Street
Use the straight / right lanes.
9

Turn right onto North Spring Street

230 ft · 10 sec · North Spring Street
10

Arrive at destination

North Spring Street

Heads-up: tricky spots

5 of 7

5 decision points cluster between mile 1.3 and 11 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
1.3 mi into trip | ~3m in | MS 145

Turn sharp left onto MS 145

Sharp turn - reduce speed on approach

5
2.8 mi into trip | ~6m in | US 45

Merge onto US 45

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
6
9.8 mi into trip | ~14m in

Take the exit toward Downtown Tupelo

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Toward Downtown Tupelo
5
11 mi into trip | ~16m in | West Main Street

Turn right onto West Main Street

Lane positioning matters here

Use the straight / right lanes.
5
11 mi into trip | ~17m in | North Spring Street

Turn right onto North Spring Street

Navigation decision point

Fuel & Cost

Regular Gas

$1.68 one way

$3.35 round trip

$3.84/gal 25.4 MPG avg 4 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $1.84 $3.68
premium $4.56 $1.99 $3.98
diesel $5.61 $2.45 $4.90

No toll roads detected on this route.

Drive Cost (one way)

Fuel

$2

Estimated CO2 emission: 3.9 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $1 in charging · 0 stops · 75% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 3.3 0 $1.17 $0.53
Efficient EV 2.8 0 $0.97 $0.44
EV Truck/SUV 4.4 0 $1.55 $0.71

Gas CO2

4 kg

EV CO2

1 kg (75% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 18, 2026

Origin

Saltillo, MS

Night in Saltillo on Saturday

Local time

11:34 PM

CDT

Current temp

77°F

Unavailable

Live forecast

Destination

Tupelo, MS

Night in Tupelo on Saturday

Local time

11:34 PM

CDT

Current temp

64°F

Partly Cloudy

S 5 mph 1% chance Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

13 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

17m on the road

The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

This drive is heavily highway-focused, with 74% of your time spent on high-speed roads. You can expect a consistent pace throughout the journey, highlighted by a longest uninterrupted stretch of 7 miles along US 45. The road maintains a practical, utilitarian personality that prioritizes speed over winding scenery. As you transition from the highway onto North 3rd Avenue and MS 145, the environment shifts toward a more localized feel. It is a no-nonsense transit that moves you quickly from start to finish without any required stops.

74% highway — fuel and pacing are the main things to plan.
10 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 7 mi on US 45.

How Hard Is This Drive?

4/10

This is a straightforward highway drive that stays mostly on US 45 and North 3rd Avenue. There are only a few real navigation decisions along the way. The trickiest moment comes around 1.3 miles in near MS 145.

Driving Effort 4/10

Easy - simple navigation with a manageable amount of wheel time

Balances navigation complexity with total wheel time.

This is a straightforward 17m drive. You will face about 7 decision points, but nothing that requires special attention if you follow navigation.

Where does it get tricky?

The main spots that need attention: at 1.3 miles (MS 145): Sharp turn - reduce speed on approach; at 2.8 miles (US 45): Merge point - match speed before joining. Lane positioning matters here; at 9.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 17m. Total distance: 11.1 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

17m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (74%). Straightforward navigation.

Frequently Asked Questions

The longest stretch is about 7 miles on US 45. The full list of main roads is in the Roads section above.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 1.3 miles (MS 145): Sharp turn - reduce speed on approach; at 2.8 miles (US 45): Merge point - match speed before joining. Lane positioning matters here; at 9.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.

Yes — Natchez Trace National Scenic Trail and Tupelo National Battlefield. See the National Parks section for detour distances and tips on detours.

Yes. A round trip is manageable in a single day if you plan a break at Tupelo, MS before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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