Origin
Saint Peters, MO
Afternoon in Saint Peters on Friday
Local time
3:20 PM
CDT
Current temp
93°F
Unavailable
Live forecast
Trip from Saint Peters, MO to Maysville, MO
Pin this tripCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Sep 4, 2026 · Editorial standards
Drive Time
5h 10m
Distance
258.9 mi
417 km
Drive Score
10/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$40
one way
EV Charging
Unknown
Best Time to Leave
4 AM
4h 57m
★
6 AM
5h 11m
8 AM
5h 38m
10 AM
5h 20m
12 PM
5h 18m
3 PM
5h 22m
5 PM
5h 36m
8 PM
5h 3m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Saint Peters, MO
Wikimedia Commons
Maysville, MO
Valeria Boltneva
Trip Overview
The drive from Saint Peters, MO to Maysville, MO covers 258.9 miles and takes about 5h 10m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Chicago-Kansas City Expressway, Avenue of the Saints, I 70 for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 156.2 miles on Chicago-Kansas City Expressway. At current regular gas prices, budget about $40.14 one way before food or hotel costs.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
129.5 miles from Saint Peters, MO
A natural place for your longest stop of the day , about 2h 35m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| Chicago-Kansas City Expressway | 156.2 mi | 3h 1m |
| Avenue of the Saints | 73.3 mi | 1h 26m |
| I 70 | 11.1 mi | 13m |
| MO 33 | 8.9 mi | 15m |
| V.F.W. Memorial Highway | 5.8 mi | 6m |
| Veterans Road | 2.2 mi | 3m |
| Paris Gravel Road | 0.5 mi | 1m |
| West Main Street | 0.1 mi | <1m |
Longest stretch:
Chicago-Kansas City Expressway
— 156.2 mi, about 3h 1m
Traffic on I-70
Hour-of-day weekday pattern from 12 FHWA count stations on your route.
Peak
2 PM
~3,147 veh/hr typical · worst 3,671
Quietest
1 AM
~263 veh/hr
Peak-to-quiet ratio
12×
busier at peak than in the quiet hours
12a
6a
noon
6p
11p
Averaged across 103 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Peters, MO and Maysville, MO.
1
Start on I 70
11 mi
·
13 min
·
I 70
Use the straight / slight right lanes.
2
Take the exit
0.4 mi
·
47 sec
Exit 210B
Toward US 61 North: Hannibal
Use the slight right lane.
3
Merge onto US 61
73 mi
·
1 hr 26 min
·
Avenue of the Saints
Use the right lane.
4
Take the exit
249 ft
·
14 sec
5
Turn left onto Paris Gravel Road
0.5 mi
·
1 min
·
Paris Gravel Road
6
Keep slight right at fork onto County Road 422
279 ft
·
8 sec
·
County Road 422
7
Turn right onto Veterans Road
2.2 mi
·
3 min
·
Veterans Road
8
Take the ramp
0.2 mi
·
16 sec
Toward US 36 West, MO 110 West: Monroe City
9
Merge onto US 36; MO 110
5.8 mi
·
6 min
·
V.F.W. Memorial Highway
10
Continue on US 24; US 36; MO 110
156 mi
·
3 hr 1 min
·
Chicago-Kansas City Expressway
11
Turn right onto MO 33
8.9 mi
·
15 min
·
MO 33
12
Turn left onto MO 6
0.1 mi
·
14 sec
·
West Main Street
13
Arrive at destination
MO 6
Trip Plan
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 129.5 miles from Saint Peters, MO, or about 2h 35m into the drive.
The longest continuous stretch on this route runs about 156.2 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 57 miles or 1h 8m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 129.5 miles or 2h 35m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 11m
Traffic, exits, and arrival timing usually matter more near Maysville, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Peters, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Peters, MO
This is one driving day of about 258.9 miles and 5h 10m.
Your first comfortable stop window is around 57 miles from Saint Peters, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Chicago-Kansas City Expressway for about 156.2 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
129 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 57 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 129.5 miles from Saint Peters, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Chicago-Kansas City Expressway if your tank is already low. That segment runs about 156.2 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 115 decision points cluster between mile 11.1 and 87.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
11.1 mi into trip
|
~13m in
Take the exit toward US 61 North: Hannibal
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 210B
Toward US 61 North: Hannibal
5
11.5 mi into trip
|
~14m in
|
US 61 / Avenue of the Saints
Merge onto US 61 / Avenue of the Saints
Merge point - match speed before joining. Lane positioning matters here
Use the right lane.
4
84.8 mi into trip
|
~1h 41m in
|
Paris Gravel Road
Turn left onto Paris Gravel Road
Navigation decision point
4
85.3 mi into trip
|
~1h 42m in
|
County Road 422
Keep slight right at fork onto County Road 422
Highway fork - watch signs carefully
6
87.6 mi into trip
|
~1h 46m in
Take the ramp toward US 36 West, MO 110 West: Monroe City
Multiple destination signs - pick the right one
Toward US 36 West, MO 110 West: Monroe City
Fuel & Cost
Regular Gas
$40.14 one way
$80.28 round trip
$3.94/gal
25.4 MPG avg
91 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.32 | $44.01 | $88.03 |
| premium | $4.93 | $50.23 | $100.46 |
| diesel | $5.60 | $57.07 | $114.14 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$40
Meals
$25–$50
Total
$65–$90
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 90.6 kg one way. Prices: EIA weekly data, 2026-08-31.
Driving Electric?
About $27 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 77.7 | 0 | $27.18 | $12.43 |
| Efficient EV | 64.7 | 0 | $22.65 | $10.36 |
| EV Truck/SUV | 103.6 | 1 | $36.25 | $16.57 |
Gas CO2
91 kg
EV CO2
30 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Maysville, MO
Afternoon in Maysville on Friday
Local time
3:20 PM
CDT
Current temp
91°F
Unavailable
Live forecast
66°F
Quincy, IL
129 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 10m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
26 mi from route
~66 min detour
$19
View on nps.gov
Park data from the National Park Service API. Alerts update every 2 hours.
What kind of drive is this?
258.9 mi in 5h 10m, mostly highway — 156.2 mi of that is on Chicago-Kansas City Expressway.
68% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 156.2 mi on Chicago-Kansas City Expressway.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on Chicago-Kansas City Expressway and Avenue of the Saints. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 11.1 miles in.
Driving Effort
5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 258.9 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 11.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 11.5 miles (US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here; at 84.8 miles (Paris Gravel Road): Navigation decision point.
Elevation Profile
Mostly flat terrain
971 ft
443 ft
Total Climb
879 ft
Total Descent
352 ft
Highest Point
971 ft
~258.9 mi in
Elevation Range
527 ft
About the Cities
Starting in Saint Peters, MO
Full guide →Founded 1910
Arriving in Maysville, MO
Full guide →Founded 1845
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 10m. Total distance: 258.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 10m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (68%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 156.2 miles on Chicago-Kansas City Expressway. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 11.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 11.5 miles (US 61 / Avenue of the Saints): Merge point - match speed before joining. Lane positioning matters here; at 84.8 miles (Paris Gravel Road): Navigation decision point.
Yes — Gateway Arch National Park. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 5.2 hours each way, a round trip means 10.4 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Maysville, MO before the return drive.
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.
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