Origin
Independence, MO
Evening in Independence on Friday
Local time
5:17 PM
CDT
Current temp
71°F
Unavailable
Live forecast
Trip from Independence, MO to Maysville, MO
Pin this tripCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Sep 4, 2026 · Editorial standards
Drive Time
1h 29m
Distance
65.8 mi
106 km
Drive Score
7/10
Good drive
Same Day?
Yes, doable
Fuel Cost
$10
one way
EV Charging
Unknown
Best Time to Leave
4 AM
1h 23m
★
6 AM
1h 29m
8 AM
1h 43m
10 AM
1h 34m
12 PM
1h 33m
3 PM
1h 35m
5 PM
1h 42m
8 PM
1h 25m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Independence, MO
Wikimedia Commons
Maysville, MO
Valeria Boltneva
Trip Overview
The drive from Independence, MO to Maysville, MO covers 65.8 miles and takes about 1h 29m behind the wheel. This route is realistic as a one-day drive if you keep your stops efficient.
The route leans on Chicago-Kansas City Expressway, MO 33, MO 291 for much of the mileage, and the overall profile is mostly highway. The longest uninterrupted segment is about 41.2 miles on Chicago-Kansas City Expressway. At current regular gas prices, budget about $10.20 one way before food or hotel costs.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| Chicago-Kansas City Expressway | 41.2 mi | 45m |
| MO 33 | 8.9 mi | 15m |
| MO 291 | 8.3 mi | 11m |
| Lightburne Street | 2.8 mi | 5m |
| West US Highway 24 | 2.1 mi | 4m |
| North Noland Road | 0.6 mi | 1m |
| South Leonard Street | 0.6 mi | 1m |
| MO 110 | 0.2 mi | <1m |
Longest stretch:
Chicago-Kansas City Expressway
— 41.2 mi, about 45m
Turn-by-Turn Driving Directions
Step-by-step road directions between Independence, MO and Maysville, MO.
1
Start on East Kansas Avenue
145 ft
·
11 sec
·
East Kansas Avenue
2
Turn left onto South Lynn Street
406 ft
·
19 sec
·
South Lynn Street
3
Turn right onto East Lexington Avenue
0.2 mi
·
28 sec
·
East Lexington Avenue
4
Turn left onto North Noland Road
0.6 mi
·
1 min
·
North Noland Road
5
Turn right onto US 24
2.1 mi
·
4 min
·
West US Highway 24
6
Turn left
0.2 mi
·
28 sec
Toward MO 291 North: Liberty
Use the left lane.
7
Merge onto MO 291
8.3 mi
·
11 min
·
MO 291
8
Turn slight right
409 ft
·
8 sec
9
Turn slight right onto South Leonard Street
0.6 mi
·
1 min
·
South Leonard Street
10
Continue on Lightburne Street
2.8 mi
·
5 min
·
Lightburne Street
11
Take the ramp
0.4 mi
·
45 sec
12
Merge onto I 35; MO 110
34 mi
·
36 min
·
Chicago-Kansas City Expressway
13
Take the exit onto MO 110
0.2 mi
·
31 sec
·
MO 110
Exit 54
Toward US 36, MO 110 East, I 35 Business: Cameron, Hamilton
14
Turn left onto US 36; MO 110
7.5 mi
·
9 min
·
Chicago-Kansas City Expressway
15
Turn right onto MO 33
8.9 mi
·
15 min
·
MO 33
16
Turn left onto MO 6
0.1 mi
·
14 sec
·
West Main Street
17
Arrive at destination
MO 6
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
33 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 14 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 32.9 miles from Independence, MO, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 105 decision points cluster between mile 0 and 49 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0 mi into trip
|
~0m in
|
South Lynn Street
Turn left onto South Lynn Street
Navigation decision point
4
0.1 mi into trip
|
~0m in
|
East Lexington Avenue
Turn right onto East Lexington Avenue
Navigation decision point
4
0.3 mi into trip
|
~1m in
|
North Noland Road
Turn left onto North Noland Road
Navigation decision point
7
3 mi into trip
|
~7m in
Turn left toward MO 291 North: Liberty
Lane positioning matters here
Use the left lane.
Toward MO 291 North: Liberty
6
49 mi into trip
|
~1h 3m in
|
MO 110
Take the exit onto MO 110 toward US 36, MO 110 East, I 35 Business: Cameron, Hamilton
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 54
Toward US 36, MO 110 East, I 35 Business: Camer...
Fuel & Cost
Regular Gas
$10.20 one way
$20.40 round trip
$3.94/gal
25.4 MPG avg
23 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.32 | $11.19 | $22.37 |
| premium | $4.93 | $12.77 | $25.53 |
| diesel | $5.60 | $14.50 | $29.01 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$10
Estimated CO2 emission: 23 kg one way. Prices: EIA weekly data, 2026-08-31.
Driving Electric?
About $7 in charging · 0 stops · 65% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 19.7 | 0 | $6.91 | $3.16 |
| Efficient EV | 16.5 | 0 | $5.76 | $2.63 |
| EV Truck/SUV | 26.3 | 0 | $9.21 | $4.21 |
Gas CO2
23 kg
EV CO2
8 kg (65% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Maysville, MO
Evening in Maysville on Friday
Local time
5:17 PM
CDT
Current temp
91°F
Unavailable
Live forecast
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
20 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 29m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
What kind of drive is this?
65.8 mi in 1h 29m, mostly highway — 41.2 mi of that is on Chicago-Kansas City Expressway.
92% highway — fuel and pacing are the main things to plan.
17 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 41.2 mi on Chicago-Kansas City Expressway.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on Chicago-Kansas City Expressway and MO 33. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near South Lynn Street.
Driving Effort
4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 29m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (South Lynn Street): Navigation decision point; at 0.1 miles (East Lexington Avenue): Navigation decision point; at 0.3 miles (North Noland Road): Navigation decision point.
Elevation Profile
Mostly flat terrain
1,064 ft
793 ft
Total Climb
455 ft
Total Descent
518 ft
Highest Point
1,064 ft
~32.9 mi in
Elevation Range
270 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Independence, MO to Maysville, MO, road signs begin pointing toward Hamilton along the way.
Hamilton
49 mi in
|
~1h 3m
|
via MO 110
About the Cities
Starting in Independence, MO
Full guide →Founded 1827
Independence, known as the Queen City of the Trails, is a city in western Missouri just east of Kansas City with a population of approximately 110,000. Independence's founding predates that of Kansas City, and it was home to U.S. President Harry S. Truman and the legendary actress Ginger Rogers, as well as the starting point of three of America's great Westward Trails: the Santa Fe Trail, the California Trail, and the Oregon Trail. The city also hosts numerous historical sites related to the Community of Christ (formerly RLDS), Church of Jesus Christ of Latter-day Saints (the "Mormons"), American Civil War and Western history. While offering a full range of entertainment and lodging options for visitors, Independence generally tends to be more "quiet" than its larger neighbor to the west.
Top landmarks
- • Harry S. Truman Presidential Library and Museum — presidential library and museum for U.S. President Harry S. Truman, located in I...
- • Temple Lot — Geographical location important in Latter Day Saint history
- • Harry S. Truman National Historic Site — national Historic Site of the United States in Missouri
Arriving in Maysville, MO
Full guide →Founded 1845
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 29m. Total distance: 65.8 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 29m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (92%). Straightforward navigation.
Frequently Asked Questions
The longest stretch is about 41.2 miles on Chicago-Kansas City Expressway. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: near the start (South Lynn Street): Navigation decision point; at 0.1 miles (East Lexington Avenue): Navigation decision point; at 0.3 miles (North Noland Road): Navigation decision point.
Yes. A round trip is manageable in a single day if you plan a break at Maysville, MO before heading back.
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and USGS 3DEP for elevation. See our methodology for refresh cadence and limitations.
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