The Wine Cafe
Near the end, right off the route
St Charles, Missouri
Hours: 11 am–8 pm
+16364108002
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
2h 44m
Distance
165.4 mi
266 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$26
one way
EV Charging
Sparse
1 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Poplar Bluff, MO
Wikimedia Commons
Saint Charles, MO
Wikimedia Commons
This 165.4-mile journey from Poplar Bluff, MO to Saint Charles, MO is a straightforward, single-day excursion, taking approximately 2 hours and 44 minutes. You'll navigate primarily on North Westwood Boulevard and State Street before merging onto I 55 North for a portion of the trip. The estimated fuel cost for this Midwest to Midwest drive is around $25. With just one recommended stop, this route is designed for efficiency, making it an ideal option if you're looking for a relatively quick trip between these Missouri cities. It's a practical drive that keeps you moving without extensive detours.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
82.7 miles from Poplar Bluff, MO
A natural place for your longest stop of the day , about 1h 22m into the drive .
| Road | Distance | Duration |
|---|---|---|
| North Westwood Boulevard | — | — |
| State Street | — | — |
| I 55 North | — | — |
| Rosa Parks Highway | — | — |
| I 270 West | — | — |
| I 70 | — | — |
| I 70 West | — | — |
| South Fifth Street | — | — |
Some road-level metrics are being recalculated.
Step-by-step road directions between Poplar Bluff, MO and Saint Charles, MO.
Start on West Pine Street
Turn right onto North Westwood Boulevard
Continue on State Street
Continue on North Westwood Boulevard
Continue straight
Continue straight
Keep slight right
Take the exit straight toward I 55 North: Saint Louis
Merge slight left
Continue on Rosa Parks Highway
Take the exit slight right toward I 270 West, I 255 East: Kansas City, Chicago
Keep slight left to continue on I 270 West: Kansas City
Continue on I 270 West
Merge slight left
Take the exit slight right toward I 70: Kansas City, Saint Louis, Saint Louis Lambert International Airport
Keep slight left to continue on I 70 West: Kansas City
Continue on I 70 West: Kansas City
Merge slight left
Take the exit slight right toward I 70 Business: Fifth Street
Keep slight right to continue on I 70 Business: Fifth Street North, Bass Pro Drive, Ameristar Boulevard
Turn slight right onto South Fifth Street
Turn right onto Jefferson Street
Turn left onto North Second Street
Arrive at your destination
Given the modest 2-hour and 44-minute duration for this 165.4-mile drive, you have a lot of flexibility with your departure time. Leaving Poplar Bluff in the morning allows for a relaxed arrival in Saint Charles by midday, with time to spare. The estimated fuel cost of $25 is quite manageable, so plan to refuel before you leave Poplar Bluff to ensure a smooth journey. With only one recommended stop, consider making it a quick pit stop for a snack or to stretch your legs. A specific tip for this route: pay close attention to local signage as you transition from I 55 North onto the local roads leading into Saint Charles, as these can change quickly.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 36 miles or 35m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 82.7 miles or 1h 22m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 15m
Traffic, exits, and arrival timing usually matter more near Saint Charles, MO than in the middle of the route.
Open the route before leaving Poplar Bluff, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Poplar Bluff, MO
This is one driving day of about 165.4 miles and 2h 44m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
83 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 36 miles helps settle the day before fatigue starts building.
The midpoint is around 82.7 miles from Poplar Bluff, MO, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
St Charles, Missouri
Near the end, right off the route
Hours: 11 am–8 pm
+16364108002
Near the end, right off the route
St Charles, Missouri
Hours: 11 am–8 pm
+16364108002
Visit websiteNear the end, ~9 min detour
St. Louis, Missouri
Hours: 11 am–12 pm
+13142009952
Visit websiteNear the end, ~10 min detour
Arnold, Missouri
Hours: 11 am–3 pm
+16363332869
Visit websiteNear the end, ~12 min detour
Maryland Heights, Missouri
Hours: 11 am–7 pm
+13147106335
Visit websiteNear the end, ~10 min detour
Kirkwood, Missouri
Hours: 8 am–3 pm
+13146982200
Visit websiteNear the start, right off the route
Poplar Bluff, Missouri
+18004891588
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
Regular Gas
$25.86 one way
$51.72 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $28.39 | $56.78 |
| premium | $4.89 | $31.83 | $63.66 |
| diesel | $5.61 | $36.52 | $73.04 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$26
Meals
$25–$50
Total
$51–$76
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 57.9 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $17 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 49.6 | 0 | $17.37 | $7.94 |
| Efficient EV | 41.4 | 0 | $14.47 | $6.62 |
| EV Truck/SUV | 66.2 | 0 | $23.16 | $10.59 |
Gas CO2
58 kg
EV CO2
19 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Night in Poplar Bluff on Saturday
Local time
9:47 PM
CDT
Current temp
83°F
Unavailable
Destination
Night in Saint Charles on Saturday
Local time
9:47 PM
CDT
Current temp
57°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Expect a turn-heavy local drive for much of this 165.4-mile route. While I 55 North offers a brief stretch of highway driving, the majority of your journey will involve navigating through local streets and roads. The highway share is 0%, indicating a consistent focus on surface streets and potentially more frequent intersections and speed changes. This means you'll need to stay alert and manage your pace as you transition between different road types. The drive progresses by moving you through more developed areas as you approach Saint Charles.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. Navigation is very simple - set it and forget it for most of the drive.
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Poplar Bluff, MO to Saint Charles, MO is easy. At 2h 44m with 0% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
This route does not have any notably tricky sections. Most of the drive from Poplar Bluff, MO to Saint Charles, MO is straightforward, with well-signed roads and simple exits.
Weekend Trip
Doable as a same-day drive at 2h 44m. Total distance: 165.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 44m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (0%). Straightforward navigation.
Scenic Drive
Mostly surface roads route profile.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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