Origin
Plymouth, PA
Afternoon in Plymouth on Sunday
Local time
1:53 PM
EDT
Current temp
50°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
2h 12m
Distance
105.9 mi
170 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$18
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Plymouth, PA
Michael Taccetta
Plymouth, PA to Harrisburg, PA is 105.9 miles and takes about 2h 12m via I 81, with a fuel budget near $18 and enough daylight to finish in a day. This is a straightforward, highway-focused trip entirely within Pennsylvania's Northeast region, making it ideal for a single-day journey. You'll primarily be on I 81, a major interstate designed for efficient travel. Given the relatively short distance and duration, it's a convenient option for moving between these two points without needing an overnight stay. The fuel cost is quite manageable, making it an economical choice.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
52.9 miles from Plymouth, PA
A natural place for your longest stop of the day , about 1h 7m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 81 | 97.9 mi | 1h 54m |
| North Cameron Street | 1.8 mi | 3m |
| Blackman Street | 1.4 mi | 3m |
| Carey Avenue | 1 mi | 2m |
| East Main Street | 0.6 mi | 1m |
| West End Road | 0.6 mi | 1m |
| Horton Street | 0.6 mi | 1m |
| Herr Street | 0.3 mi | <1m |
Step-by-step road directions between Plymouth, PA and Harrisburg, PA.
Start on West Railroad Street
Turn right onto South Center Avenue
Turn right onto US 11
Turn right onto Carey Avenue
Continue on West End Road
Turn left onto Carey Avenue
Turn right onto Horton Street
Continue on Blackman Street
Turn right onto PA 309
Take the ramp
Merge onto I 81
Take the exit onto US 322
Keep slight left at fork
Merge onto US 22
Turn right onto Herr Street
Turn right onto North 7th Street
Arrive at destination
Since this trip is just over 2 hours and covers 105.9 miles, you have a lot of flexibility with your departure time. Leaving in the morning is a good way to ensure you have plenty of daylight to complete the drive comfortably, especially since there are no recommended stops. The longest uninterrupted stretch is nearly 98 miles on I 81, so plan to take a break before or after this long segment if you need to stretch your legs. Keep an eye on your fuel level as you approach Harrisburg, as gas stations can become less frequent on the interstate itself.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 23 miles or 32m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 52.9 miles or 1h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 47m
Traffic, exits, and arrival timing usually matter more near Harrisburg, PA than in the middle of the route.
Open the route before leaving Plymouth, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Plymouth, PA
This is one driving day of about 105.9 miles and 2h 12m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
53 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 23 miles helps settle the day before fatigue starts building.
The midpoint is around 52.9 miles from Plymouth, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 81 if your tank is already low. That segment runs about 97.9 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 0.1 and 103.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn right onto US 11 / East Main Street
Lane positioning matters here
Merge onto I 81
Merge point - match speed before joining. Lane positioning matters here
Take the exit onto US 322 toward US 22 East, PA 230 East, US 22 West, US 322 West: Harrisburg, Lewistown, State College
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight left at fork toward US 22 East: Harrisburg, Cameron Street
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Merge onto US 22 / North Cameron Street
Merge point - match speed before joining. Lane positioning matters here
Regular Gas
$17.56 one way
$35.11 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $19.23 | $38.46 |
| premium | $4.93 | $20.54 | $41.08 |
| diesel | $5.61 | $23.38 | $46.76 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$18
Meals
$25–$50
Total
$43–$68
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 37.1 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging · 0 stops · 68% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 31.8 | 0 | $11.12 | $5.08 |
| Efficient EV | 26.5 | 0 | $9.27 | $4.24 |
| EV Truck/SUV | 42.4 | 0 | $14.83 | $6.78 |
Gas CO2
37 kg
EV CO2
12 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Afternoon in Plymouth on Sunday
Local time
1:53 PM
EDT
Current temp
50°F
Unavailable
Destination
Afternoon in Harrisburg on Sunday
Local time
1:53 PM
EDT
Current temp
88°F
Mostly Sunny
Special Weather Statement
Special Weather Statement issued April 16 at 4:45AM EDT by NWS Mount Holly NJ
Special Weather Statement
Special Weather Statement issued April 16 at 4:42AM EDT by NWS State College PA
42°F
East Franklin, PA
53 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Scenic Trail
The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...
National Monument
More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...
Park data from the National Park Service API. Alerts update every 2 hours.
This route is predominantly a highway-focused drive, with 93% of it being on major roadways like I 81. Expect a consistent experience for the majority of your journey, especially during the longest stretch of 97.9 miles on I 81. The profile suggests a generally smooth and direct path, minimizing complex turns or slower local roads. While the main roads include North Cameron Street and Blackman Street, these are likely brief transitions within the cities at either end, with I 81 dominating the driving experience.
This is a straightforward highway drive that stays mostly on I 81 and North Cameron Street. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 0.1 miles in near US 11 / East Main Street.
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 105.9 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (US 11 / East Main Street): Lane positioning matters here; at 4.7 miles (I 81): Merge point - match speed before joining. Lane positioning matters here; at 102.7 miles (US 322): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Harrisburg is the capital and 4th-largest metropolitan area of Pennsylvania, with a metro population of 592,000 people in 2020. Harrisburg is known as the host city of the Pennsylvania Farm Show, the largest free indoor agriculture exposition in the United States, the largest annual outdoor sports show in North America, an auto show, which features a large static display of new and classic cars, and Motorama, a two-day event consisting of a car show, motocross racing, and remote control car racing.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 2h 12m. Total distance: 105.9 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
2h 12m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (93%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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