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Trip from Philadelphia, PA to Tyrone, PA

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards

Drive Time

4h 27m

Distance

219.3 mi

353 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$36

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
4h 14m ★
6 AM
4h 27m
8 AM
4h 54m
10 AM
4h 37m
12 PM
4h 34m
3 PM
4h 38m
5 PM
4h 53m
8 PM
4h 19m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

largest city in Pennsylvania, United States

Philadelphia, PA

Wikimedia Commons

Downtown Tyrone, PA, PA

Tyrone, PA

Wikimedia Commons

Trip Overview

Philadelphia to Tyrone is 219.3 miles and takes about 4h 27m via Pennsylvania Turnpike and US 322, with a fuel budget near $36 and enough daylight to finish in a day. This trip stays within the Northeast region, remaining entirely within Pennsylvania. You'll primarily be on major highways, making for a straightforward drive. Consider this route if you're looking for an efficient way to travel between these two points in a single day, with minimal fuss. The highway-focused nature means you can cover ground quickly and arrive with time to spare.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

109.7 miles from Philadelphia, PA

A natural place for your longest stop of the day , about 2h 10m into the drive .

Main Roads

Road Distance Duration
Pennsylvania Turnpike 78.8 mi 1h 24m
US 322 54.4 mi 1h 7m
US 22 24.5 mi 32m
Mount Nittany Expressway 17.5 mi 21m
Schuylkill Expressway 16.8 mi 23m
I 99 13.9 mi 14m
I 83 3.7 mi 5m
I 283 2.8 mi 4m
Longest stretch: Pennsylvania Turnpike — 78.8 mi, about 1h 24m

Turn-by-Turn Driving Directions

Step-by-step road directions between Philadelphia, PA and Tyrone, PA.

1

Start on South Penn Square

397 ft · 8 sec · South Penn Square
2

Keep slight left at fork onto PA 611

0.1 mi · 19 sec · East Penn Square
Use the straight lane.
3

Continue on John F. Kennedy Boulevard

0.2 mi · 20 sec · John F. Kennedy Boulevard
Use the straight lane.
4

Turn right onto North 16th Street

0.4 mi · 54 sec · North 16th Street
Use the right lane.
5

Take the ramp

0.2 mi · 27 sec
Toward I 676 West, US 30 West: International Airport, Valley Forge Use the right lane.
6

Merge onto I 676; US 30

1.0 mi · 1 min · Vine Street Expressway
Use the straight / slight right lanes.
7

Merge onto I 76; US 30

16 mi · 22 min · Schuylkill Expressway
Use the straight / slight right lanes.
8

Take the exit

0.1 mi · 10 sec
Exit 328B-A/327 Toward US 202, US 422 West: King of Prussia, West Chester, Pottstown Use the slight right lane.
9

Keep slight left at fork

0.3 mi · 22 sec
Toward US 202 South, US 422 West: Mall Boulevard, West Chester, Pottstown, Swedesford Road Use the straight / slight right lanes.
10

Keep slight left at fork

0.3 mi · 20 sec
Toward Mall Boulevard Use the straight / slight right lanes.
11

Keep slight left at fork

0.1 mi · 8 sec
Toward I 76 West: New Jersey, Harrisburg
12

Merge onto I 76

0.4 mi · 52 sec · Schuylkill Expressway
Toward I 76 West: New Jersey, Harrisburg
13

Keep slight left at fork onto I 76

0.4 mi · 1 min · I 76
Toward I 76 West: Harrisburg Use the slight left lane.
14

Merge onto I 76; PATP

79 mi · 1 hr 24 min · Pennsylvania Turnpike
Use the straight / slight right lanes.
15

Take the exit

0.3 mi · 1 min
Exit 247 Toward I 283, PA 283: Harrisburg, Hershey Use the slight right lane.
16

Continue on I 283

2.5 mi · 3 min · I 283
17

Keep slight right at fork onto I 283

0.2 mi · 30 sec · I 283
Exit 3B-C Toward I 83 North, US 322
18

Keep slight left at fork

0.3 mi · 34 sec
Exit 3B Toward I 83 North, US 322 West: Hazleton, State College
19

Continue on I 83

3.7 mi · 5 min · I 83
20

Continue on US 322

2.4 mi · 3 min · US 322
Exit 51A Toward I 81 South, US 322 West: Carlisle, State College
21

Take the exit onto US 322

0.3 mi · 27 sec · US 322
Exit 67A; 67B Toward US 22 East, PA 230 East, US 22 West, US 322 West: Harrisburg, Lewistown, State College
22

Keep slight right at fork onto US 322

52 mi · 1 hr 3 min · US 322
Exit 67B Toward US 22 West, US 322 West: Lewistown, State College Use the slight right lane.
23

Keep slight left at fork onto US 22; US 322

24 mi · 32 min · US 22; US 322
Toward US 22 West, US 322 West: Mount Union, State College
24

Continue on US 322; PA 144 Truck

2.6 mi · 4 min · Boal Avenue
Use the straight / right lanes.
25

Continue on US 322; PA 144 Truck

18 mi · 21 min · Mount Nittany Expressway
26

Keep slight left at fork onto I 99; US 220

14 mi · 14 min · I 99; US 220
Toward I 99 South, US 220 South: Port Matilda, Altoona
27

Take the exit

0.3 mi · 44 sec
Toward PA 453: Tyrone
28

Turn right onto PA 453

0.1 mi · 20 sec · PA 453
29

Turn left onto US 220 Business

493 ft · 12 sec · Pennsylvania Avenue
30

Turn right onto US 220 Business

87 ft · 1 sec · West 10th Street
31

Arrive at destination

US 220 Business

Trip Plan

With a drive time under five hours, this route is easily manageable as a same-day trip. Aim to depart Philadelphia in the morning to take advantage of daylight and allow for any unexpected delays. The longest stretch on the Pennsylvania Turnpike means you can plan your fuel stops strategically, perhaps before entering that segment. Since you'll be on major highways for most of the way, keep an eye on traffic conditions, especially around Philadelphia. With only one recommended stop, you have flexibility to decide when and where to take a break.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 109.7 miles from Philadelphia, PA, or about 2h 10m into the drive.
The longest continuous stretch on this route runs about 78.8 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 48 miles or 59m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 109.7 miles or 2h 10m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 38m

Traffic, exits, and arrival timing usually matter more near Tyrone, PA than in the middle of the route.

Before You Leave

+

Open the route before leaving Philadelphia, PA so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Philadelphia, PA

This is one driving day of about 219.3 miles and 4h 27m.

Your first comfortable stop window is around 48 miles from Philadelphia, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Pennsylvania Turnpike for about 78.8 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Enola, PA, PA

Mid-route town

Meal stop

Enola, PA

110 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Warwick, PA

Fuel and coffee

A short stop after about 48 miles helps settle the day before fatigue starts building.

Harrisburg, PA

Meal break

The midpoint is around 109.7 miles from Philadelphia, PA, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Pennsylvania Turnpike if your tank is already low. That segment runs about 78.8 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 24

5 decision points cluster between mile 18.4 and 108.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

8
18.4 mi into trip | ~26m in

Take the exit toward US 202, US 422 West: King of Prussia, West Chester, Pottstown

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 328B-A/327 Toward US 202, US 422 West: King of Prussia, We...
9
18.5 mi into trip | ~26m in

Keep slight left at fork toward US 202 South, US 422 West: Mall Boulevard, West Chester, Pottstown, Swedesford Road

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward US 202 South, US 422 West: Mall Boulevar...
8
18.8 mi into trip | ~27m in

Keep slight left at fork toward Mall Boulevard

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes. Toward Mall Boulevard
8
98.7 mi into trip | ~1h 54m in

Take the exit toward I 283, PA 283: Harrisburg, Hershey

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 247 Toward I 283, PA 283: Harrisburg, Hershey
9
108.4 mi into trip | ~2h 9m in | US 322

Keep slight right at fork onto US 322 toward US 22 West, US 322 West: Lewistown, State College

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 67B Toward US 22 West, US 322 West: Lewistown, Stat...

Fuel & Cost

Regular Gas

$36.36 one way

$72.71 round trip

$4.21/gal 25.4 MPG avg 77 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.61 $39.82 $79.64
premium $4.93 $42.53 $85.06
diesel $5.61 $48.42 $96.84

Estimated Tolls: $10.24

Pennsylvania Turnpike (78.8 mi) $10.24

Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.

Estimated Trip Cost (one way, 1 person)

Fuel

$36

Tolls

$10

Meals

$25–$50

Total

$72–$97

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 76.7 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $23 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 65.8 0 $23.03 $10.53
Efficient EV 54.8 0 $19.19 $8.77
EV Truck/SUV 87.7 1 $30.70 $14.04

Gas CO2

77 kg

EV CO2

26 kg (66% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 20, 2026

Origin

Philadelphia, PA

Late night in Philadelphia on Tuesday

Local time

4:10 AM

EDT

Current temp

64°F

Unavailable

Live forecast

Destination

Tyrone, PA

Late night in Tyrone on Tuesday

Local time

4:10 AM

EDT

Current temp

62°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

2 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 27m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Independence National Historical Park

Independence National Historical Park

National Historical Park

The park represents the founding ideals of the nation, and preserves national and international symbols of freedom and democracy, including Independence Hall and the Liberty Bell. The Declaration of I...

1 mi from route ~2 min detour $1
Park Closure: Congress Hall Temporary Closure
View on nps.gov
Thaddeus Kosciuszko National Memorial

Thaddeus Kosciuszko National Memorial

National Memorial

Visit the house where wounded Polish freedom fighter Thaddeus Kosciuszko lived and hear how this brilliant military engineer designed successful fortifications during the American Revolution. See the...

1 mi from route ~3 min detour Free
View on nps.gov
Valley Forge National Historical Park

Valley Forge National Historical Park

National Historical Park

Valley Forge is the place where George Washington and the Continental Army took refuge during the winter of 1777-1778. Today the park protects 3,500 acres of meadows, woodlands, historic landscapes, a...

2 mi from route ~4 min detour Free near mile 22.7
View on nps.gov
Appalachian National Scenic Trail

Appalachian National Scenic Trail

National Scenic Trail

The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...

13 mi from route ~33 min detour Free near mile 75.6
View on nps.gov
First State National Historical Park

First State National Historical Park

National Historical Park

Famous as the First State to ratify the Constitution, Delaware was born out of a conflict among three world powers for dominance of the Delaware Valley. From this beginning, the region developed a dis...

16 mi from route ~41 min detour Free near mile 30.3
View on nps.gov
Carlisle Federal Indian Boarding School National Monument

Carlisle Federal Indian Boarding School National Monument

National Monument

More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...

17 mi from route ~41 min detour Free near mile 121
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

This is a highway-focused drive, with 98% of the journey on major roads. Expect to spend most of your time on the Pennsylvania Turnpike and US 22. The longest uninterrupted stretch you'll encounter is 78.8 miles on the Pennsylvania Turnpike, offering a period of consistent speed. While largely highway, the route transitions to US 322 and US 22 as you approach your destination, providing a slight change in scenery and road type. Overall, it's designed for covering distance efficiently.

98% highway — fuel and pacing are the main things to plan.
31 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 78.8 mi on Pennsylvania Turnpike.

How Hard Is This Drive?

10/10

This is a straightforward highway drive that stays mostly on Pennsylvania Turnpike and US 322. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 18.4 miles in.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 24 significant decision points across 219.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 18.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 18.5 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 18.8 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Philadelphia, PA and Tyrone, PA, road signs point toward Chester, Pottstown, Harrisburg, Hershey, State College and Lewistown - among others.

Chester

18.4 mi in | ~26m

Pottstown

18.4 mi in | ~26m

Harrisburg

19 mi in | ~27m

Hershey

98.7 mi in | ~1h 54m

State College

101.7 mi in | ~1h 59m

Lewistown

108.1 mi in | ~2h 8m | via US 322

Altoona

204.8 mi in | ~4h 11m | via I 99; US 220

About the Cities

Starting in Philadelphia, PA

Full guide →

“City of Brotherly Love” · Founded 1682

Top landmarks

  • Independence Hall — historic building in Philadelphia, Pennsylvania, USA
  • Liberty Bell — bell in Philadelphia, Pennsylvania, USA that serves as a symbol of American inde...
  • Philadelphia Museum of Art — art museum in Philadelphia, Pennsylvania

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 27m. Total distance: 219.3 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 27m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (98%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 78.8 miles on Pennsylvania Turnpike. The full list of main roads is in the Roads section above.

Expect about $10.24 in tolls one way, starting with Pennsylvania Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Tyrone, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 18.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 18.5 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 18.8 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Yes — Independence National Historical Park, Thaddeus Kosciuszko National Memorial and Valley Forge National Historical Park (6 total within detour distance). See the National Parks section for detour distances and tips on detours.

Possible but tiring. At 4.5 hours each way, an in-and-out day trip would put you behind the wheel for 8.9 hours — manageable with a long break at Tyrone, PA, but most travelers stay overnight.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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