Tyrone, PA to Reading, PA is 176.7 miles and takes about 3 hours 30 minutes via Keystone Shortway and I-99, with a fuel budget near $29 and enough daylight to finish in a day. This drive primarily stays within Pennsylvania, moving from the Northeast region to another part of the Northeast. Expect a route that involves frequent turns and a significant amount of local road driving, making it a more engaging trip than a simple interstate cruise. It's a manageable distance for a single-day journey, allowing for a relaxed pace.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
88.3 miles from Tyrone, PA
A natural place for your longest stop of the day
, about 1h 38m into the drive
.
Main Roads
Road
Distance
Duration
Keystone Shortway
63.4 mi
1h 8m
I 99
37.6 mi
42m
State Route 54
11.1 mi
13m
Center Avenue
10.6 mi
12m
Pottsville Pike
10.2 mi
12m
Elysburg Road
9.7 mi
11m
Sunbury Road
9.4 mi
11m
Centre Street
4.2 mi
5m
Longest stretch:
Keystone Shortway
— 63.4 mi, about 1h 8m
Turn-by-Turn Driving Directions
Step-by-step road directions between Tyrone, PA and Reading, PA.
1
Start on US 220 Business
87 ft·8 sec·West 10th Street
2
Turn left onto US 220 Business
493 ft·12 sec·Pennsylvania Avenue
3
Turn right onto PA 453
0.2 mi·21 sec·East 11th Street
4
Turn left
0.4 mi·45 sec
5
Merge onto I 99; US 220
21 mi·22 min·I 99; US 220
6
Keep slight left at fork onto I 99; US 220; US 322
4.0 mi·4 min·I 99; US 220; US 322
Use the straight lane.
7
Keep slight left at fork onto I 99; US 220
12 mi·14 min·I 99; US 220
Toward I 99 North, US 220 North: Bellefonte
8
Turn left
0.2 mi·31 sec
Toward I 80 East, US 220 North: WilliamsportUse the left lane.
9
Merge onto I 80; US 220
63 mi·1 hr 8 min·Keystone Shortway
10
Take the exit
0.2 mi·26 sec
Toward PA 54: Danville, Washingtonville
11
Turn slight left
79 ft·2 sec
12
Turn right onto PA 54
2.9 mi·3 min·Continental Boulevard
Use the straight / right lanes.
13
Continue on PA 54
0.1 mi·19 sec·Factory Street
14
Continue on PA 54
0.3 mi·49 sec·Danville-Riverside Bridge Road
15
Turn left onto PA 54
9.7 mi·11 min·Elysburg Road
Use the left lane.
16
Continue on PA 54
11 mi·13 min·State Route 54
17
Continue on PA 901
0.4 mi·41 sec·Locust Gap Highway
18
Continue on PA 901
2.2 mi·2 min·Fairgrounds Road
19
Continue on PA 901
9.4 mi·11 min·Sunbury Road
20
Continue on PA 901
0.8 mi·1 min·Sunbury Street
21
Turn right onto PA 901
1.8 mi·2 min·Pottsville Minersville Highway
22
Turn right onto PA 901
4.0 mi·6 min·Gordon Nagle Trail
23
Continue on PA 901
0.2 mi·33 sec·North Sillyman Street
24
Turn left onto PA 183
0.7 mi·2 min·Pottsville Street
25
Turn right onto PA 61
493 ft·6 sec·Route 61 South
26
Continue on PA 61
11 mi·12 min·Center Avenue
Use the straight / right lanes.
27
Continue on PA 61
4.2 mi·5 min·Centre Street
28
Continue on PA 61
0.3 mi·17 sec·South 4th Street
29
Continue on PA 61
2.3 mi·2 min·Pottsville Pike
Use the straight / right lanes.
30
Continue on PA 61
0.6 mi·43 sec·Shoemaker Avenue
Use the straight / right lanes.
31
Continue on PA 61
3.2 mi·3 min·Pottsville Pike
Use the straight / right lanes.
32
Continue on PA 61
1.0 mi·1 min·North Centre Avenue
Use the left / straight / right lanes.
33
Continue on PA 61
4.7 mi·6 min·Pottsville Pike
Use the straight lane.
34
Continue on PA 61
2.8 mi·4 min·Centre Avenue
Use the straight lane.
35
Continue on PA 61
0.8 mi·1 min·North 4th Street
36
Turn left onto US 422 Business
0.2 mi·27 sec·Franklin Street
37
Turn left onto South 6th Street
0.1 mi·24 sec·South 6th Street
Use the straight / left lanes.
38
Turn left onto US 422 Business Alternate
278 ft·4 sec·Penn Street
39
Arrive at destination
US 422 Business Alternate
Trip Plan
Given the 3 hour 30 minute duration, this is comfortably a one-day trip. Aim to depart in the morning to take full advantage of daylight and allow for any unexpected delays. With only one recommended stop and a turn-heavy profile, planning your route in advance using a reliable GPS is key. The estimated fuel cost is $29, so ensure your vehicle is adequately fueled before you begin, especially as you'll be on local roads for a significant portion of the drive. Keep an eye out for State Route 54 as you approach your destination, as this is a key part of the latter half of the journey.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 88.3 miles from Tyrone, PA, or about 1h 38m into the drive.
The longest continuous stretch on this route runs about 63.4 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 39 miles or 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 88.3 miles or 1h 38m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 47m
Traffic, exits, and arrival timing usually matter more near Reading, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Tyrone, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Tyrone, PA
This is one driving day of about 176.7 miles and 3h 30m.
Your first comfortable stop window is around 39 miles from Tyrone, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Keystone Shortway for about 63.4 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
The midpoint is around 88.3 miles from Tyrone, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel check
Top up before Keystone Shortway if your tank is already low. That segment runs about 63.4 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Stops Along Your Drive
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Gibraltar Park
4.1
★ ★ ★ ★ ☆
Near the end, ~12 min detour
Home stretch
4.7 mi from route
~12 min detour
Birdsboro, Pennsylvania
Hours: 6 am–9 pm
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 17
5 decision points cluster between mile 21.9 and 176.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
21.9 mi into trip|~24m in|I 99; US 220; US 322
Keep slight left at fork onto I 99; US 220; US 322
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
6
25.9 mi into trip|~29m in|I 99; US 220
Keep slight left at fork onto I 99; US 220 toward I 99 North, US 220 North: Bellefonte
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 99 North, US 220 North: Bellefonte
7
38.2 mi into trip|~43m in
Turn left toward I 80 East, US 220 North: Williamsport
Lane positioning matters here. Multiple destination signs - pick the right one
Use the left lane.
Toward I 80 East, US 220 North: Williamsport
5
101.9 mi into trip|~1h 52m in
Take the exit toward PA 54: Danville, Washingtonville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward PA 54: Danville, Washingtonville
6
176.5 mi into trip|~3h 29m in|South 6th Street
Turn left onto South 6th Street
Lane positioning matters here
Use the straight / left lanes.
Fuel & Cost
Regular Gas
$29.29 one way
$58.59 round trip
$4.21/gal25.4 MPG avg62 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.61
$32.08
$64.17
premium
$4.93
$34.27
$68.54
diesel
$5.61
$39.01
$78.03
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$29
Meals
$25–$50
Total
$54–$79
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 61.8 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $19 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
53
0
$18.55
$8.48
Efficient EV
44.2
0
$15.46
$7.07
EV Truck/SUV
70.7
0
$24.74
$11.31
Gas CO2
62 kg
EV CO2
21 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Tyrone, PA
Morning
in Tyrone on Tuesday
Local time
6:08 AM
EDT
Current temp
62°F
Unavailable
Live forecast
Destination
Reading, PA
Morning
in Reading on Tuesday
Local time
6:08 AM
EDT
Current temp
47°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
15 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 30m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This route offers a turn-heavy local drive experience, with only 28% of the journey on highways. You'll encounter a mix of road types, transitioning from highway stretches like the Keystone Shortway and I-99 to State Route 54 and other local roads. The longest uninterrupted stretch you'll experience is 63.4 miles on the Keystone Shortway, providing a period of more consistent travel before you dive back into more varied terrain. Be prepared for a dynamic driving experience that requires attention to navigation and road changes.
Only 28% highway — the rest is turn-by-turn surface driving.
39 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 63.4 mi on Keystone Shortway.
How Hard Is This Drive?
8/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 21.9 miles in near I 99; US 220; US 322.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 176.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 21.9 miles (I 99; US 220; US 322): Highway fork - watch signs carefully. Lane positioning matters here; at 25.9 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 38.2 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Tyrone, PA to Reading, PA, road signs begin pointing toward Washingtonville along the way.
Reading is a historic city of about 95,000 (2020 Census) in Pennsylvania, about 50 miles northwest of Philadelphia, 35 miles southwest of Allentown and 55 miles east of Harrisburg. It punches above its weight in culture, and its downtown features some iconic buildings, so consider making it a stopover on your way between any of these and other area cities.
Doable as a same-day drive at 3h 30m. Total distance: 176.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 30m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile.
Frequently Asked Questions
The longest stretch is about 63.4 miles on Keystone Shortway. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Reading, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 21.9 miles (I 99; US 220; US 322): Highway fork - watch signs carefully. Lane positioning matters here; at 25.9 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 38.2 miles: Lane positioning matters here. Multiple destination signs - pick the right one.
Possible but tiring. At 3.5 hours each way, an in-and-out day trip would put you behind the wheel for 7.0 hours — manageable with a long break at Reading, PA, but most travelers stay overnight.
