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Trip from Northampton, PA to Pittsburgh, PA

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Oct 18, 2026 · Editorial standards

Drive Time

5h 39m

Distance

286.8 mi

461 km

Drive Score

9/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$50

one way

EV Charging

Good

8 stations

Best Time to Leave

Save up to 39 min
4 AM
5h 27m ★
6 AM
5h 40m
8 AM
6h 6m
10 AM
5h 49m
12 PM
5h 47m
3 PM
5h 51m
5 PM
6h 5m
8 PM
5h 32m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

borough in Pennsylvania, United States of America

Northampton, PA

Wikimedia Commons

city and county seat in Allegheny County, Pennsylvania, United States

Pittsburgh, PA

Wikimedia Commons

Trip Overview

Northampton to Pittsburgh is 286.8 miles and takes about 5h 39m via Pennsylvania Turnpike, with a fuel budget near $47 and enough daylight to finish in a day. This drive keeps you within Pennsylvania, moving from the Northeast region towards Pittsburgh. It's a straightforward trip, mostly on highways, making it a convenient option for a single-day journey. You can expect a fairly direct path with minimal deviations, ideal if you prefer to cover ground efficiently.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

143.4 miles from Northampton, PA

A natural place for your longest stop of the day , about 2h 55m into the drive .

Main Roads

Road Distance Duration
Pennsylvania Turnpike 170.5 mi 3h 7m
William Penn Highway 43.1 mi 51m
I 81 36.6 mi 44m
Penn-Lincoln Parkway East 13.2 mi 18m
78th Division Highway 7.6 mi 8m
Lehigh Valley Thruway 6.2 mi 8m
Main Street 2.1 mi 3m
Harrisburg Pike 1 mi 2m
Longest stretch: Pennsylvania Turnpike — 170.5 mi, about 3h 7m

Traffic on I-81

Hour-of-day weekday pattern from 56 FHWA count stations on your route.

Peak

4 PM

~2,821 veh/hr typical · worst 3,332

Quietest

1 AM

~392 veh/hr

Peak-to-quiet ratio

7.2×

busier at peak than in the quiet hours

12a 6a noon 6p 11p

Averaged across 101 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).

Turn-by-Turn Driving Directions

Step-by-step road directions between Northampton, PA and Pittsburgh, PA.

1

Start on Main Street

0.6 mi · 1 min · Main Street
2

Keep slight left at fork onto Main Street

1.5 mi · 2 min · Main Street
3

Turn left onto 4th Street

510 ft · 12 sec · 4th Street
4

Turn right onto Cypress Street

432 ft · 10 sec · Cypress Street
5

Continue on Eugene Street

356 ft · 12 sec · Eugene Street
6

Turn left onto 2nd Street

0.6 mi · 1 min · 2nd Street
7

Turn right onto Pine Street

0.8 mi · 1 min · Pine Street
8

Turn right onto Main Street

0.1 mi · 12 sec · Main Street
9

Continue on Mickley Road

0.6 mi · 1 min · Mickley Road
10

Turn left onto PA 145

0.5 mi · 1 min · MacArthur Road
Use the straight lane.
11

Take the exit

0.2 mi · 29 sec
Toward US 22 West: Harrisburg Use the right lane.
12

Merge onto US 22

6.2 mi · 8 min · Lehigh Valley Thruway
Use the straight / slight right lanes.
13

Merge onto I 78; US 22

43 mi · 51 min · William Penn Highway
Use the straight lane.
14

Continue on I 78; US 22

7.6 mi · 8 min · 78th Division Highway
15

Keep slight left at fork

0.7 mi · 49 sec
Exit 1B Toward I 81 South: Harrisburg
16

Merge onto I 81

37 mi · 44 min · I 81
17

Take the exit

0.3 mi · 48 sec
Exit 52 Toward US 11: New Kingstown, Middlesex Use the slight right lane.
18

Keep slight right at fork

201 ft · 7 sec
Toward US 11 South Use the right lane.
19

Merge onto US 11

1.0 mi · 2 min · Harrisburg Pike
Use the straight / right lanes.
20

Take the exit

0.5 mi · 1 min
Toward I 76, PATP
21

Keep slight right at fork

0.2 mi · 37 sec
Toward I 76 West: Pittsburgh Use the slight right lane.
22

Merge onto I 76; PATP

171 mi · 3 hr 7 min · Pennsylvania Turnpike
23

Take the exit

0.6 mi · 2 min
Exit 57 Toward I 376 West, US 22: Pittsburgh, Monroeville Use the slight right lane.
24

Keep slight left at fork

0.2 mi · 23 sec
Toward US 22 Business, I 376 West, US 22 West: Monroeville, Pittsburgh
25

Keep slight right at fork

353 ft · 8 sec
Toward I 376 West, US 22 West: Pittsburgh
26

Merge onto I 376; US 22

13 mi · 18 min · Penn-Lincoln Parkway East
Use the slight left lane.
27

Take the exit

0.2 mi · 38 sec
Exit 71B Toward Second Avenue Use the straight / slight right lanes.
28

Turn straight onto Second Avenue

0.3 mi · 41 sec · Second Avenue
29

At end of road, turn right onto Ross Street

0.2 mi · 32 sec · Ross Street
30

Turn left onto Fifth Avenue

352 ft · 10 sec · Fifth Avenue
31

Turn right onto Grant Street

513 ft · 21 sec · Grant Street
Use the right lane.
32

Arrive at destination

Grant Street

Trip Plan

Given the 5h 39m estimated drive time, leaving Northampton in the morning should allow you to reach Pittsburgh well before evening. The single recommended stop suggests a brief pause, perhaps for fuel or a quick meal. You'll be on the Pennsylvania Turnpike for the longest stretch, so ensure you're prepared for tolls and potentially higher speeds. Keep an eye on your fuel levels, as the $47 estimated cost is based on the total distance, and prices can vary along the route.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 143.4 miles from Northampton, PA, or about 2h 55m into the drive.
The longest continuous stretch on this route runs about 170.5 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 63 miles or 1h 20m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 143.4 miles or 2h 55m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 36m

Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.

Before You Leave

+

Open the route before leaving Northampton, PA so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Northampton, PA

This is one driving day of about 286.8 miles and 5h 39m.

Your first comfortable stop window is around 63 miles from Northampton, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Pennsylvania Turnpike for about 170.5 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

title given to the name of a male monarch

Mid-route town

Meal stop

King, PA

143 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Hershey, PA

Fuel and coffee

A short stop after about 63 miles helps settle the day before fatigue starts building.

State Line, PA

Meal break

The midpoint is around 143.4 miles from Northampton, PA, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Pennsylvania Turnpike if your tank is already low. That segment runs about 170.5 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Stops Along Your Drive

Picked by where they fit in your drive — first break, midpoint reset, final stretch.

Best meal stop · home stretch

Kiku Japanese Restaurant

4.5 ★ ★ ★ ★ ★

Pittsburgh, Pennsylvania

Near the end, right off the route

Home stretch · 0min to go 0.7 mi from route ~2 min detour $20 to $30

Hours: 12–2 pm

+14127653200

Visit website

Grand Concourse

4.2 ★ ★ ★ ★ ☆

Pittsburgh, Pennsylvania

0.7 mi

J & J's Family Restaurant & Catering

4.6 ★ ★ ★ ★ ★

Pittsburgh, Pennsylvania

1 mi

Kiku Japanese Restaurant

4.5 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.7 mi from route ~2 min detour $20 to $30

Pittsburgh, Pennsylvania

Hours: 12–2 pm

+14127653200

Visit website

Grand Concourse

4.2 ★ ★ ★ ★ ☆

Near the end, right off the route

Home stretch 0.7 mi from route ~2 min detour Expensive

Pittsburgh, Pennsylvania

Hours: 11:30 am–9:30 pm

+14122611717

Visit website

J & J's Family Restaurant & Catering

4.6 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 1 mi from route ~2 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 8 am–5 pm

+14123811822

Cambod-Ican Kitchen Restaurant

4.6 ★ ★ ★ ★ ★

Near the end, short detour

Home stretch 1.1 mi from route ~3 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 5:30 pm–2 am

+14123816199

Visit website

KAVSAR RESTAURANT

4.4 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 1 mi from route ~3 min detour Moderately

Pittsburgh, Pennsylvania

Hours: 4–9:30 pm

+14124888708

Visit website

La Tavola Italiana Restaurant

4.5 ★ ★ ★ ★ ★

Near the end, short detour

Home stretch 1.1 mi from route ~3 min detour $30 to $50

Pittsburgh, Pennsylvania

Hours: 5–9 pm

+14124813336

Visit website

Nino's Restaurant

4.4 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 1.6 mi from route ~4 min detour $20 to $30

Mt Pleasant, Pennsylvania

Hours: Closed

+17245472900

Visit website

Zarra's Restaurant

4.2 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 2.4 mi from route ~6 min detour Moderately

Pittsburgh, Pennsylvania

Hours: 5–9:30 pm

+14126828296

Visit website

Orbis Caffe

4.6 ★ ★ ★ ★ ★

Near the end, ~12 min detour

Home stretch 4.8 mi from route ~12 min detour $1 to $10

Pittsburgh, PA

Hours: 7 am–9 pm

+14125631220

Visit website

Autel Charging Station

5.0 ★ ★ ★ ★ ★

Near the end, ~9 min detour

Home stretch 3.6 mi from route ~9 min detour

Pittsburgh, Pennsylvania

Hours: Open 24 hours

Tesla Supercharger

4.3 ★ ★ ★ ★ ☆

Near the end, ~11 min detour

Home stretch 4.5 mi from route ~11 min detour

North Huntingdon, Pennsylvania

Hours: Open 24 hours

Visit website

Tesla Supercharger

4.3 ★ ★ ★ ★ ☆

Near the end, ~11 min detour

Home stretch 4.3 mi from route ~11 min detour

North Huntingdon, Pennsylvania

Hours: Open 24 hours

+18777983752

Visit website

ChargeSmart EV Charging Station

5.0 ★ ★ ★ ★ ★

Near the end, ~12 min detour

Home stretch 4.6 mi from route ~12 min detour

Adamsburg, Pennsylvania

Hours: Open 24 hours

+18887174544

Visit website

Cochran Charging Station

3.0 ★ ★ ★ ☆ ☆

Near the end, ~9 min detour

Home stretch 3.6 mi from route ~9 min detour

Pittsburgh, Pennsylvania

Hours: Open 24 hours

Visit website

Electric Vehicle Charging Station

1.0 ★ ☆ ☆ ☆ ☆

Near the end, ~10 min detour

Home stretch 4.2 mi from route ~10 min detour

Pittsburgh, Pennsylvania

Hours: Open 24 hours

Tesla Destination Charger

Near the end, ~10 min detour

Home stretch 3.9 mi from route ~10 min detour

Acme, Pennsylvania

Hours: Open 24 hours

+18778337829

Visit website

ChargeSmart EV Charging Station

Near the end, ~12 min detour

Home stretch 4.9 mi from route ~12 min detour

Castle Shannon, Pennsylvania

Hours: 9 am–8 pm

+18887174544

Visit website

North Somerset Service Plaza

0 mi from route

South Somerset Service Plaza

0 mi from route

South Midway Service Plaza

0 mi from route

North Midway Service Plaza

0 mi from route

Blue Mountain Service Plaza

0 mi from route

Rest Area

0 mi from route

Love's Travel Stop

0.1 mi from route

Petro Stopping Centers

0.1 mi from route

Flying J Travel Center

0.1 mi from route

New Stanton Service Plaza

0.1 mi from route

Sideling Hill Service Plaza

0.1 mi from route

Rest Area

0.1 mi from route

TA

0.2 mi from route

Love's Travel Stop

0.2 mi from route

ONE9 Travel Center

0.2 mi from route

Flying J Travel Center

0.2 mi from route

Flying J Travel Center

0.2 mi from route

Cumberland Valley Service Plaza

0.4 mi from route

Service Plaza

0.4 mi from route

TA

0.6 mi from route

Flying J Travel Center

0.6 mi from route

Love's Travel Stop

1.5 mi from route

Allentown Service Plaza

1.6 mi from route

Primanti Bros. Restaurant and Bar

4.3 ★ ★ ★ ★ ☆

Near the end, right off the route

Home stretch 0.4 mi from route ~1 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 10:30 am–12 pm

+14122611599

Visit website

Primanti Bros. Restaurant and Bar

4.5 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.9 mi from route ~2 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 8 am–12 pm

+14122632142

Visit website

Primanti Bros. Restaurant and Bar

4.2 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 1.2 mi from route ~3 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 11 am–1 pm

+14123812583

Visit website

Primanti Bros. Restaurant and Bar

4.3 ★ ★ ★ ★ ☆

Near the end, short detour

Home stretch 2.1 mi from route ~5 min detour $10 to $20

Pittsburgh, Pennsylvania

Hours: 11 am–12 pm

+14126214444

Visit website

Primanti Bros. Restaurant and Bar

4.2 ★ ★ ★ ★ ☆

Near the end, ~12 min detour

Home stretch 4.8 mi from route ~12 min detour $10 to $20

Homestead, Pennsylvania

Hours: 11 am–12 pm

+14124611469

Visit website

Luma | Wine Bar & Restaurant

4.6 ★ ★ ★ ★ ★

Near the end, ~12 min detour

Home stretch 5 mi from route ~12 min detour $40 to $50

Pittsburgh, Pennsylvania

Hours: 4–9 pm

+14123430355

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 25

5 decision points cluster between mile 99.4 and 272.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

8
99.4 mi into trip | ~2h 4m in

Take the exit toward US 11: New Kingstown, Middlesex

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 52 Toward US 11: New Kingstown, Middlesex
8
99.6 mi into trip | ~2h 4m in

Keep slight right at fork toward US 11 South

Highway fork - watch signs carefully. Lane positioning matters here

Use the right lane. Toward US 11 South
7
101.1 mi into trip | ~2h 8m in

Keep slight right at fork toward I 76 West: Pittsburgh

Highway fork - watch signs carefully. Lane positioning matters here

Use the slight right lane. Toward I 76 West: Pittsburgh
8
271.9 mi into trip | ~5h 16m in

Take the exit toward I 376 West, US 22: Pittsburgh, Monroeville

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 57 Toward I 376 West, US 22: Pittsburgh, Monroevil...
7
272.7 mi into trip | ~5h 19m in

Keep slight right at fork toward I 376 West, US 22 West: Pittsburgh

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 376 West, US 22 West: Pittsburgh

Fuel & Cost

Regular Gas

$50.47 one way

$100.94 round trip

$4.47/gal 25.4 MPG avg 100 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.89 $55.19 $110.38
premium $5.23 $59.01 $118.02
diesel $6.18 $69.77 $139.54

Estimated Tolls: $22.60

Pennsylvania Turnpike (170.5 mi) $22.17
Lehigh Valley Thruway (6.2 mi) $0.43

Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.

Estimated Trip Cost (one way, 1 person)

Fuel

$50

Tolls

$23

Meals

$25–$50

Total

$98–$123

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 100.3 kg one way. Prices: EIA weekly data, 2026-10-12.

Driving Electric?

About $30 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 86 1 $30.11 $13.77
Efficient EV 71.7 0 $25.10 $11.47
EV Truck/SUV 114.7 1 $40.15 $18.36

Gas CO2

100 kg

EV CO2

34 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Oct 17, 2026

Origin

Northampton, PA

Night in Northampton on Saturday

Local time

9:37 PM

EDT

Current temp

51°F

Partly Sunny

N 10 to 15 mph 11% chance Live forecast

Freeze Warning

Freeze Warning issued October 17 at 2:10AM EDT until October 18 at 9:00AM EDT by NWS Mount Holly NJ

Freeze Warning

Freeze Warning issued October 17 at 2:10AM EDT until October 18 at 9:00AM EDT by NWS Mount Holly NJ

Destination

Pittsburgh, PA

Night in Pittsburgh on Saturday

Local time

9:37 PM

EDT

Current temp

41°F

Mostly Cloudy

W 5 to 8 mph 13% chance Live forecast

Freeze Warning

Freeze Warning issued October 17 at 2:10AM EDT until October 18 at 9:00AM EDT by NWS Mount Holly NJ

Freeze Warning

Freeze Warning issued October 17 at 2:10AM EDT until October 18 at 9:00AM EDT by NWS Mount Holly NJ

40°F

King, PA

143 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

10 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 39m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Appalachian National Scenic Trail

Appalachian National Scenic Trail

National Scenic Trail

The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...

3 mi from route ~8 min detour Free near mile 59.3
Park Closure: List of trail closures post-Hurricane Helene
Caution: Black Bears Frequenting the McAfee Knob Area in Virginia
View on nps.gov
Carlisle Federal Indian Boarding School National Monument

Carlisle Federal Indian Boarding School National Monument

National Monument

More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...

4 mi from route ~10 min detour Free near mile 98.9
View on nps.gov
Flight 93 National Memorial

Flight 93 National Memorial

National Memorial

On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...

6 mi from route ~15 min detour Free near mile 207.7
View on nps.gov
Fort Necessity National Battlefield

Fort Necessity National Battlefield

National Battlefield

The battle at Fort Necessity in the summer of 1754 was the opening action of the French and Indian War. This war was a clash of British, French and American Indian cultures. It ended with the removal...

23 mi from route ~59 min detour Free near mile 237.3
View on nps.gov
Johnstown Flood National Memorial

Johnstown Flood National Memorial

National Memorial

The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...

25 mi from route ~62 min detour Free near mile 187.9
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

This route is primarily highway driving, with 77% of the trip on major roads. You'll spend a significant stretch on the Pennsylvania Turnpike, including a continuous segment of 170.5 miles. After the highway portions, you'll transition to William Penn Highway and I 81, which will likely involve more local traffic and a different driving pace. Expect to encounter a higher density of exits and interchanges as you approach your destination.

77% highway — fuel and pacing are the main things to plan.
32 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 170.5 mi on Pennsylvania Turnpike.

How Hard Is This Drive?

10/10

This is a straightforward highway drive that stays mostly on Pennsylvania Turnpike and William Penn Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 99.4 miles in.

Driving Effort 10/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 25 significant decision points across 286.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 99.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 99.6 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 101.1 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Elevation Profile

Hilly terrain with moderate elevation changes

2,609 ft 324 ft

Total Climb

3,191 ft

Total Descent

2,749 ft

Highest Point

2,609 ft

~205 mi in

Elevation Range

2,286 ft

Notable High Points

1,673 ft at ~164 miles +537 ft prominence
2,609 ft at ~205 miles +1,473 ft prominence

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Northampton, PA and Pittsburgh, PA, road signs point toward Middlesex, Patp and Monroeville.

Middlesex

99.4 mi in | ~2h 4m

Patp

100.7 mi in | ~2h 7m

Monroeville

271.9 mi in | ~5h 16m

About the Cities

Starting in Northampton, PA

Full guide →

Founded 1867

Arriving in Pittsburgh, PA

Full guide →

Founded 1758

The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.

Top landmarks

  • • Carnegie Museum of Natural History — natural history museum in Pittsburgh, Pennsylvania, United States
  • • Carnegie Museum of Art — museum in Pittsburgh, Pennsylvania
  • • Andy Warhol Museum — art museum in Pittsburgh, Pennsylvania

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 39m. Total distance: 286.8 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 39m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (77%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 170.5 miles on Pennsylvania Turnpike. The full list of main roads is in the Roads section above.

Expect about $22.60 in tolls one way, starting with Pennsylvania Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.

Yes — we found about 23 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Pittsburgh, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 23 rest areas along the route for bathroom stops.

The main spots that need attention: at 99.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 99.6 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 101.1 miles: Highway fork - watch signs carefully. Lane positioning matters here.

Yes — Appalachian National Scenic Trail, Carlisle Federal Indian Boarding School National Monument and Flight 93 National Memorial (5 total within detour distance). See the National Parks section for detour distances and tips on detours.

Not recommended in a single day. At 5.7 hours each way, a round trip means 11.3 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Pittsburgh, PA before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.

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