Origin
Millersburg, PA
Morning in Millersburg on Sunday
Local time
6:23 AM
EDT
Current temp
68°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
5h 47m
Distance
295 mi
475 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$49
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Millersburg, PA
Wikimedia Commons
Erie, PA
Wikimedia Commons
Millersburg, PA to Erie, PA is 295 miles and takes about 5h 47m via Keystone Shortway and I-79, with a fuel budget near $49 and enough daylight to finish in a day. This drive primarily traverses Pennsylvania, taking you from the Northeast region towards the Lake Erie area. It's a manageable one-day trip that offers a mixed driving experience, balancing highway speeds with more local road sections. Consider this route if you're looking for a straightforward journey across the state without extensive planning.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
147.5 miles from Millersburg, PA
A natural place for your longest stop of the day , about 3h 4m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Keystone Shortway | 102.7 mi | 1h 50m |
| I 79 | 65.8 mi | 1h 10m |
| US 22 | 64.5 mi | 1h 19m |
| Mount Nittany Expressway | 17.5 mi | 21m |
| Port Matilda Highway | 10.1 mi | 14m |
| Philipsburg Bigler Highway | 7.1 mi | 8m |
| South River Road | 5.9 mi | 8m |
| River Road North | 4.2 mi | 6m |
Step-by-step road directions between Millersburg, PA and Erie, PA.
Start on US 209
Turn left onto PA 147
Continue on PA 147
Continue on PA 147
Continue on PA 147
Turn left onto PA 147
Turn right onto PA 147; PA 225
Continue on PA 147; PA 225
Turn right onto PA 147
Take the ramp
Continue on US 22; US 322
Keep slight left at fork onto US 22; US 322
Continue on US 322; PA 144 Truck
Continue on US 322; PA 144 Truck
Keep slight right at fork onto US 322
Continue on US 322
Continue on US 322
Turn right onto US 322; PA 53
Continue on US 322; PA 53
Continue on US 322
Continue on US 322
Turn right onto PA 970
Take the exit
Merge onto I 80
Take the exit
Merge onto I 79
Take the exit
Turn right onto PA 5; PA 290
Turn left onto State Street
Arrive at destination
Given the 5h 47m estimated duration, departing in the morning allows ample time to reach Erie before evening. With only one recommended stop and a reasonable fuel cost of $49, you can be quite flexible with your pacing. Keep an eye on your fuel gauge, especially during the 102.7-mile stretch on the Keystone Shortway, as services can be more spread out in that section. This is a comfortable one-day drive, so you don't need to worry about breaking it up, but remember to factor in potential traffic delays as you approach Erie.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 65 miles or 1h 22m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 147.5 miles or 3h 4m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 46m
Traffic, exits, and arrival timing usually matter more near Erie, PA than in the middle of the route.
Open the route before leaving Millersburg, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Millersburg, PA
This is one driving day of about 295 miles and 5h 47m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
148 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 65 miles helps settle the day before fatigue starts building.
The midpoint is around 147.5 miles from Millersburg, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Keystone Shortway if your tank is already low. That segment runs about 102.7 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 53.7 and 294.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Keep slight left at fork onto US 22; US 322 toward US 22 West, US 322 West: Mount Union, State College
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork onto US 322 / 28th Division Highway toward US 322 West: Philipsburg
Highway fork - watch signs carefully
Take the exit
Exit ramp - move to the correct lane early
Take the exit toward PA 5 East, PA 290 East: 12th Street
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Turn left onto State Street
Lane positioning matters here
Regular Gas
$48.91 one way
$97.81 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $53.56 | $107.13 |
| premium | $4.93 | $57.21 | $114.42 |
| diesel | $5.61 | $65.13 | $130.26 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$49
Meals
$25–$50
Total
$74–$99
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 103.2 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $31 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 88.5 | 1 | $30.97 | $14.16 |
| Efficient EV | 73.8 | 0 | $25.81 | $11.80 |
| EV Truck/SUV | 118 | 1 | $41.30 | $18.88 |
Gas CO2
103 kg
EV CO2
35 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Millersburg on Sunday
Local time
6:23 AM
EDT
Current temp
68°F
Unavailable
Destination
Morning in Erie on Sunday
Local time
6:23 AM
EDT
Current temp
60°F
Unavailable
71°F
Clearfield, PA
148 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Monument
More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...
National Scenic Trail
The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...
Park data from the National Park Service API. Alerts update every 2 hours.
This trip features a "mixed drive" profile, with about 50% of the journey on highways. You'll spend a significant portion on the Keystone Shortway, experiencing its longest uninterrupted stretch of 102.7 miles. As you progress, the route transitions, incorporating I-79 for faster travel before eventually utilizing US 22. Expect a varied driving experience, shifting between quicker highway segments and potentially slower sections as you navigate different road types across the state.
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 53.7 miles in near US 22; US 322.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 295 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 53.7 miles (US 22; US 322): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 98.4 miles (US 322 / 28th Division Highway): Highway fork - watch signs carefully; at 122.5 miles: Exit ramp - move to the correct lane early.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Millersburg, PA to Erie, PA, road signs begin pointing toward State College along the way.
State College
Millersburg is a borough in the Harrisburg area of Pennsylvania.in dauphin county
Erie is a city of about 100,000 in Northwestern Pennsylvania. It is Pennsylvania's only lake port on the Great Lakes (Lake Erie).
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 5h 47m. Total distance: 295 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 47m drive, comfortable solo distance.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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