Mazzio’s Pizza & Wings
Near the start, right off the route
Madison, Mississippi
Hours: 11 am–9 pm
+16018537778
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
3h 21m
Distance
155.3 mi
250 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$23
one way
EV Charging
Fair
2 stations
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Madison, MS
Wikimedia Commons
Aberdeen, MS
Wikimedia Commons
If you are planning a trip from Madison to Aberdeen, you are looking at a straightforward 155.3-mile journey through the heart of Mississippi. Expect to spend about 3 hours and 21 minutes behind the wheel, making this a very manageable one-day trip. You will primarily rely on MS 25 and US Highway 45 Alternate to navigate the route. With an estimated fuel cost of $24, it is an affordable excursion that fits easily into a single day of travel. Because both cities are firmly within the Southeast, you will experience consistent regional characteristics throughout the drive. It is a practical choice for those who prefer a direct, highway-focused path over complex navigation.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
77.7 miles from Madison, MS
A natural place for your longest stop of the day , about 1h 42m into the drive .
| Road | Distance | Duration |
|---|---|---|
| MS 25 | 100.1 mi | 2h |
| East Peace Street | 23.4 mi | 34m |
| US Highway 45 Alternate | 15.9 mi | 21m |
| United States Highway 51 | 9.1 mi | 13m |
| Canton Parkway | 2.8 mi | 3m |
| Old Sharon Road | 1.2 mi | 2m |
| US 45 | 0.7 mi | 1m |
| South Matubba Street | 0.7 mi | 1m |
Step-by-step road directions between Madison, MS and Aberdeen, MS.
Start on Depot Drive
Turn left onto Main Street
Turn left onto US 51
Turn right onto MS 16
At end of road, turn left onto MS 16; MS 43
Turn right
Turn right onto MS 16
Take the ramp
Merge onto MS 25
Take the exit onto MS 25
Keep slight right at fork onto MS 25
Continue on MS 25
Keep slight right at fork onto MS 25
Take the exit
Merge onto US 45 ALT; MS 25
Take the exit onto MS 25
Continue on US 45; MS 8; MS 25
Turn left onto South Matubba Street
Turn right onto MS 145
Turn right onto South Meridian Street
Arrive at destination
To keep your travel smooth, plan for at least one dedicated stop to stretch your legs during the 3-hour and 21-minute drive. Since the route is efficient, you have the flexibility to depart at a time that best suits your schedule without worrying about complex overnight logistics. Keep a close eye on your fuel gauge as you head out; even with the $24 estimate, it is wise to fill up before leaving Madison to ensure you have plenty of range for the 155.3-mile distance. Because MS 25 makes up the bulk of your travel, stay alert for changes in speed limits as you move through different segments of the highway. Utilizing that one planned stop effectively will help you stay refreshed for the final stretch into Aberdeen.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 34 miles or 51m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 77.7 miles or 1h 42m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 39m
Traffic, exits, and arrival timing usually matter more near Aberdeen, MS than in the middle of the route.
Open the route before leaving Madison, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Madison, MS
This is one driving day of about 155.3 miles and 3h 21m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
78 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 34 miles helps settle the day before fatigue starts building.
The midpoint is around 77.7 miles from Madison, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before MS 25 if your tank is already low. That segment runs about 100.1 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Restaurants, cafes, gas stations and more along your route.
Top Restaurant
Madison, Mississippi
Near the start, right off the route
Hours: 11 am–9 pm
+17693000654
Arepas Coffee & Bar
Starkville, Mississippi
Ward's Restaurant
Carthage, Mississippi
Top Coffee Stop
Starkville, Mississippi
Later in the drive, short detour
Hours: 6 am–5 pm
+16622688075
Starbucks Coffee Company
Starkville, Mississippi
The Brewed Bean
Carthage, Mississippi
Near the start, right off the route
Madison, Mississippi
Hours: 11 am–9 pm
+16018537778
Visit websiteNear the start, right off the route
Madison, Mississippi
Hours: 11 am–9 pm
+17693000654
Visit websiteNear the end, right off the route
Aberdeen, Mississippi
Hours: 7 am–10 pm
+16623698181
Visit websiteLater in the drive, short detour
Starkville, Mississippi
Hours: 7 am–9 pm
+16626178058
Visit websiteEarly in the drive, short detour
Carthage, Mississippi
Hours: 6 am–10 pm
+16012674555
Visit websiteEarly in the drive, short detour
Carthage, Mississippi
Hours: 6 am–5 pm
+16012678653
Visit websiteAround the midpoint, short detour
Louisville, Mississippi
+16627737853
Visit websiteLater in the drive, short detour
Starkville, Mississippi
Hours: 10:30 am–9 pm
+16623236094
Visit websiteLater in the drive, short detour
Starkville, Mississippi
Hours: 6 am–5 pm
+16622688075
Visit websiteLater in the drive, short detour
Starkville, Mississippi
Hours: 5 am–8 pm
+16625469555
Early in the drive, short detour
Carthage, Mississippi
Hours: 6:30 am–5:30 pm
+17692846050
Visit websiteLater in the drive, ~9 min detour
Starkville, Mississippi
Hours: 6:30 am–5 pm
+16622683139
Around the midpoint, ~10 min detour
Louisville, Mississippi
Hours: 6:30 am–1 pm
Later in the drive, ~9 min detour
Starkville, Mississippi
Hours: 6 am–5 pm
+16622688413
Around the midpoint, ~10 min detour
Louisville, Mississippi
Hours: 5 am–1 pm
+16627362807
Later in the drive, ~9 min detour
Starkville, Mississippi
Hours: 6 am–4 pm
+16017453504
Visit websiteLater in the drive, ~9 min detour
Starkville, Mississippi
Hours: Open 24 hours
Visit websiteNear the end, short detour
West Point, Mississippi
Hours: Open 24 hours
Visit websiteAround the midpoint, short detour
Louisville, Mississippi
Hours: 6 am–7 pm
+16627738323
Visit websiteLater in the drive, short detour
Starkville, Mississippi
Hours: 6 am–9 pm
+16623232294
Visit websiteLater in the drive, short detour
Mississippi State, Mississippi
Hours: 5:30 am–11 pm
+16623257529
Visit websiteLater in the drive, short detour
Starkville, Mississippi
Hours: 10 am–10 pm
+16622687601
Visit websiteLater in the drive, ~9 min detour
Starkville, Mississippi
Hours: 9 am–6 pm
+16623232766
Visit websiteLater in the drive, ~9 min detour
Starkville, Mississippi
Hours: Open 24 hours
+16623236674
Visit websiteLater in the drive, ~9 min detour
Starkville, Mississippi
Hours: 8 am–4:30 pm
+16623233133
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 0 and 127.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn left onto Main Street
Navigation decision point
At end of road, turn left onto MS 16; MS 43 / Old Sharon Road
Navigation decision point
Keep slight right at fork onto MS 25
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork onto MS 25 toward US 82 East, MS 25 North: Columbus, West Point
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Take the exit toward US 45 Alternate North, MS 25 North: West Point, Tupelo
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Regular Gas
$23.45 one way
$46.91 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $25.75 | $51.49 |
| premium | $4.56 | $27.87 | $55.75 |
| diesel | $5.61 | $34.29 | $68.58 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$23
Meals
$25–$50
Total
$48–$73
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 54.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $16 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 46.6 | 0 | $16.31 | $7.45 |
| Efficient EV | 38.8 | 0 | $13.59 | $6.21 |
| EV Truck/SUV | 62.1 | 0 | $21.74 | $9.94 |
Gas CO2
54 kg
EV CO2
18 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Madison on Sunday
Local time
2:54 AM
CDT
Current temp
79°F
Unavailable
Destination
Late night in Aberdeen on Sunday
Local time
2:54 AM
CDT
Current temp
77°F
Unavailable
78°F
Louisville, MS
78 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
This trip is defined by a high highway share of 83%, keeping you on faster, more efficient roads for the majority of the journey. You will spend a significant portion of your time on MS 25, which features a long, uninterrupted stretch of 100.1 miles. Transitioning onto East Peace Street and US Highway 45 Alternate keeps the pace steady as you move toward your destination. While the drive is heavily highway-focused, the personality of the road shifts as you navigate these primary corridors. You can expect a consistent, predictable driving experience that allows you to focus on the road ahead without the constant interruption of smaller, local intersections.
This is a straightforward highway drive that stays mostly on MS 25 and East Peace Street. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive near Main Street.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 15 significant decision points across 155.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: near the start (Main Street): Navigation decision point; at 12.1 miles (MS 16; MS 43 / Old Sharon Road): Navigation decision point; at 109.4 miles (MS 25): Highway fork - watch signs carefully. Lane positioning matters here.
Mostly flat terrain
Total Climb
594 ft
Total Descent
698 ft
Highest Point
615 ft
~84.1 mi in
Elevation Range
402 ft
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Madison, MS and Aberdeen, MS, road signs point toward Point and Tupelo.
Point
Tupelo
Weekend Trip
Doable as a same-day drive at 3h 21m. Total distance: 155.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 21m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (83%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and NPS for national parks. See our methodology for refresh cadence and limitations.
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