Spanning 155.4 miles across Mississippi, this drive from Aberdeen to Madison is a straightforward journey that typically takes 3 hours and 22 minutes. Since the entire route sits within the Southeast, you will find a consistent regional feel as you transition between these two Mississippi hubs. It is perfectly manageable as a one-day trip, meaning you won't need to worry about booking an overnight stay. With a fuel budget of approximately $24, the trip remains an affordable option for travelers. Whether you are heading to Madison for business or visiting family, this highway-focused route provides a reliable and efficient connection.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
77.7 miles from Aberdeen, MS
A natural place for your longest stop of the day
, about 1h 40m into the drive
.
Main Roads
Road
Distance
Duration
MS 25
101 mi
2h 2m
MS 16
24.8 mi
37m
US Highway 45 Alternate
15.5 mi
20m
South Liberty Street
11.5 mi
17m
South Matubba Street
0.7 mi
1m
US 45
0.7 mi
1m
West Commerce Street
0.5 mi
<1m
Main Street
0.2 mi
<1m
Longest stretch:
MS 25
— 101 mi, about 2h 2m
Turn-by-Turn Driving Directions
Step-by-step road directions between Aberdeen, MS and Madison, MS.
1
Start on South Meridian Street
80 ft·7 sec·South Meridian Street
2
Turn left onto MS 145
0.5 mi·58 sec·West Commerce Street
3
Turn left onto South Matubba Street
0.7 mi·1 min·South Matubba Street
4
Take the ramp
372 ft·9 sec
5
Merge onto US 45; MS 8; MS 25
0.7 mi·1 min·US 45; MS 8; MS 25
6
Turn left onto MS 25
8.9 mi·15 min·MS 25
Use the left lane.
7
Take the ramp onto MS 25
0.7 mi·1 min·MS 25
Toward US 45 Alternate South, MS 25 South: West Point
8
Merge onto US 45 ALT; MS 25
15 mi·20 min·US Highway 45 Alternate
Use the straight lane.
9
Take the exit onto MS 25
12 mi·13 min·MS 25
Toward US 82 West, MS 12 West, MS 25 South: Starkville
10
Take the exit onto MS 25
5.0 mi·6 min·MS 25
Toward MS 25 South: Louisville
11
Continue on MS 25
1.9 mi·2 min·MS 25
Use the left lane.
12
Keep slight right at fork onto MS 25
25 mi·28 min·MS 25
13
Take the exit onto MS 25
48 mi·54 min·MS 25
14
Take the exit
0.4 mi·56 sec
15
Keep slight left at fork
156 ft·4 sec
16
Turn right onto MS 16
25 mi·37 min·MS 16
17
Turn left onto US 51; MS 16
11 mi·17 min·South Liberty Street
18
Turn right onto Main Street
0.2 mi·34 sec·Main Street
19
Turn right onto Depot Drive
36 ft·1 sec·Depot Drive
20
Arrive at destination
Depot Drive
Trip Plan
To make the most of your 3-hour and 22-minute trek, plan for at least one dedicated stop to stretch your legs and refuel. Since the trip is relatively short, you have the flexibility to leave whenever suits your schedule, though departing early helps you avoid potential traffic near the Madison area. Keep an eye on your gas gauge before starting the 101-mile stretch on MS 25 to ensure you remain within your $24 fuel budget. By pacing yourself with that single planned stop, you can keep your energy levels high throughout the 155.4-mile transit. Remember that because this is a highway-heavy route, staying alert for changing speed limits as you pass through different zones is your best strategy for a smooth arrival.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 77.7 miles from Aberdeen, MS, or about 1h 40m into the drive.
The longest continuous stretch on this route runs about 101 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 34 miles or 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 77.7 miles or 1h 40m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 40m
Traffic, exits, and arrival timing usually matter more near Madison, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Aberdeen, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Aberdeen, MS
This is one driving day of about 155.4 miles and 3h 22m.
Your first comfortable stop window is around 34 miles from Aberdeen, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on MS 25 for about 101 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 2 and 155.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
2 mi into trip|~3m in|MS 25
Turn left onto MS 25
Lane positioning matters here
Use the left lane.
4
10.9 mi into trip|~19m in|MS 25
Take the ramp onto MS 25 toward US 45 Alternate South, MS 25 South: West Point
Multiple destination signs - pick the right one
Toward US 45 Alternate South, MS 25 South: West...
5
11.5 mi into trip|~20m in|US 45 ALT; MS 25 / US Highway 45 Alternate
Merge onto US 45 ALT; MS 25 / US Highway 45 Alternate
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
5
27 mi into trip|~41m in|MS 25
Take the exit onto MS 25 toward US 82 West, MS 12 West, MS 25 South: Starkville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 82 West, MS 12 West, MS 25 South: Sta...
5
155.4 mi into trip|~3h 22m in|Depot Drive
Turn right onto Depot Drive
Navigation decision point
Fuel & Cost
Regular Gas
$23.47 one way
$46.94 round trip
$3.84/gal25.4 MPG avg54 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$25.76
$51.53
premium
$4.56
$27.89
$55.78
diesel
$5.61
$34.31
$68.62
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$23
Meals
$25–$50
Total
$48–$73
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 54.4 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $16 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
46.6
0
$16.32
$7.46
Efficient EV
38.9
0
$13.60
$6.22
EV Truck/SUV
62.2
0
$21.76
$9.95
Gas CO2
54 kg
EV CO2
18 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Aberdeen, MS
Late night
in Aberdeen on Sunday
Local time
2:54 AM
CDT
Current temp
77°F
Unavailable
Live forecast
Destination
Madison, MS
Late night
in Madison on Sunday
Local time
2:54 AM
CDT
Current temp
79°F
Unavailable
Live forecast
78°F
Louisville, MS
78 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 22m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
10 mi from route
~25 min detour
Free
near mile 155.4
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a drive defined by steady highway travel, as 91% of your journey stays on major routes like MS 25, MS 16, and US Highway 45 Alternate. You will settle into a rhythm quickly, especially during the longest stretch of 101 miles found on MS 25. The road character is consistent, favoring efficient highway transit over technical or winding local roads. Behind the wheel, you can anticipate a focused experience that prioritizes steady progress toward your destination. It is a practical, no-nonsense drive that keeps you moving through the Mississippi landscape with ease.
91% highway — fuel and pacing are the main things to plan.
20 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 101 mi on MS 25.
How Hard Is This Drive?
7/10
This is a straightforward highway drive that stays mostly on MS 25 and MS 16. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 2 miles in near MS 25.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 155.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 2 miles (MS 25): Lane positioning matters here; at 10.9 miles (MS 25): Multiple destination signs - pick the right one; at 11.5 miles (US 45 ALT; MS 25 / US Highway 45 Alternate): Merge point - match speed before joining. Lane positioning matters here.
Elevation Profile
Mostly flat terrain
603 ft214 ft
Total Climb
635 ft
Total Descent
530 ft
Highest Point
603 ft
~71.2 mi in
Elevation Range
389 ft
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 3h 22m. Total distance: 155.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 22m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (91%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 101 miles on MS 25. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Madison, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 2 miles (MS 25): Lane positioning matters here; at 10.9 miles (MS 25): Multiple destination signs - pick the right one; at 11.5 miles (US 45 ALT; MS 25 / US Highway 45 Alternate): Merge point - match speed before joining. Lane positioning matters here.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.4 hours each way, an in-and-out day trip would put you behind the wheel for 6.8 hours — manageable with a long break at Madison, MS, but most travelers stay overnight.
