The Exchange Coffee, Mercantile & Eatery
Near the end, ~9 min detour
De Pere, Wisconsin
Hours: 7 am–2 pm
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
4h 47m
Distance
221 mi
356 km
Drive Score
7/10
Good drive
Same Day?
Yes, doable
Fuel Cost
$35
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
La Crosse, WI
Wikimedia Commons
Cooperstown, WI
Tom Fisk
La Crosse, WI to Cooperstown, WI is 221 miles and takes about 4h 47m via I-90, I-41, and State Highway 82, with a fuel budget near $35 and enough daylight to finish in a day. This trip stays within Wisconsin, connecting two points in the Midwest region. With 91% of the drive on highways, expect a fairly direct and efficient trip. This route is a solid option if you're looking for a single-day drive that gets you where you need to go without excessive complexity.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
110.5 miles from La Crosse, WI
A natural place for your longest stop of the day , about 2h 22m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 90 | 62.5 mi | 1h 7m |
| I 41 | 47.4 mi | 51m |
| State Highway 82 | 28.3 mi | 42m |
| State Highway 23 | 16 mi | 23m |
| State Highway 44 | 14.8 mi | 21m |
| State Highway 23 & 73 | 9.5 mi | 13m |
| I 43 | 9 mi | 9m |
| WI 172 | 5.4 mi | 6m |
Step-by-step road directions between La Crosse, WI and Cooperstown, WI.
Start on WI 35
Turn right
Turn straight onto CTH F
Turn left onto Losey Boulevard North
Continue on WI 16
Take the ramp
Merge onto I 90
Take the exit
Turn left onto State Highway 82
Continue on State Highway 82
At end of road, turn left onto State Highway 82
Continue on WI 82
Continue on WI 82
Continue on WI 82
Continue on State Highway 23
Continue on WI 23
Continue on WI 23; CTH C
Continue on WI 22; WI 23; CTH C
Continue on WI 23
Continue on WI 23
Turn right onto WI 73; CTH J
Turn right onto WI 23; WI 73; CTH D
Continue on WI 23; WI 73
Continue on WI 23; WI 49
Continue on WI 23; WI 49
Turn left onto CTH FF
Turn straight onto West Oshkosh Street
Keep slight left at fork onto East Oshkosh Street
Continue on WI 44
Continue on WI 44; WI 91
Continue on WI 44; WI 91
Turn left
Merge onto I 41; US 41
Take the exit
Keep slight left at fork
Keep slight right at fork
Keep slight right at fork
Merge onto WI 172
Keep slight right at fork
Merge onto I 43
Take the exit
Keep slight left at fork
Turn left onto WI 96
Continue on CTH KB
Enter roundabout onto CTH KB
Continue on CTH KB
Turn right onto CTH R
Arrive at destination
This 4-hour, 47-minute drive is easily manageable in a single day, so consider leaving in the morning to give yourself plenty of time. With only one recommended stop and a relatively short longest stretch of 62.5 miles, you can be flexible with your breaks. The fuel cost is estimated around $35, so factor that into your budget. Keep an eye on your fuel gauge, especially as you transition from I-41 to State Highway 82, as services might become less frequent on the latter.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 49 miles or 1h in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 110.5 miles or 2h 22m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 58m
Traffic, exits, and arrival timing usually matter more near Cooperstown, WI than in the middle of the route.
Open the route before leaving La Crosse, WI so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from La Crosse, WI
This is one driving day of about 221 miles and 4h 47m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
111 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 49 miles helps settle the day before fatigue starts building.
The midpoint is around 110.5 miles from La Crosse, WI, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 90 if your tank is already low. That segment runs about 62.5 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Best coffee break · home stretch
Allouez, Wisconsin
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Hours: 7 am–2 pm
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De Pere, Wisconsin
Hours: 7 am–2 pm
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Green Bay, Wisconsin
Hours: 7 am–2 pm
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Green Bay, Wisconsin
Hours: 7 am–3 pm
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Allouez, Wisconsin
Hours: 7 am–2 pm
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De Pere, Wisconsin
Hours: 6:30 am–2 pm
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Green Bay, Wisconsin
Hours: 7 am–3 pm
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Appleton, Wisconsin
Hours: 7 am–3 pm
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Green Bay, Wisconsin
Hours: 6 am–5:30 pm
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Green Bay, Wisconsin
Hours: 7 am–2 pm
+19202722222
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Appleton, Wisconsin
Hours: 4–9 pm
+19202053780
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 69.6 and 200.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the exit toward WI 82: Mauston, Oxford
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Turn left toward I-41_North: Appleton
Complex interchange - multiple decisions in a short stretch
Merge onto I 41; US 41 toward Appleton
Merge point - match speed before joining. Lane positioning matters here
Keep slight left at fork toward WI 172: Austin Straubel Airport
Highway fork - watch signs carefully
Keep slight right at fork toward WI 172: Austin Straubel Airport
Highway fork - watch signs carefully
Regular Gas
$34.55 one way
$69.10 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $37.94 | $75.87 |
| premium | $4.89 | $42.53 | $85.06 |
| diesel | $5.61 | $48.79 | $97.59 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$35
Meals
$25–$50
Total
$60–$85
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 77.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $23 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 66.3 | 0 | $23.21 | $10.61 |
| Efficient EV | 55.3 | 0 | $19.34 | $8.84 |
| EV Truck/SUV | 88.4 | 1 | $30.94 | $14.14 |
Gas CO2
77 kg
EV CO2
26 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in La Crosse on Tuesday
Local time
3:54 AM
CDT
Current temp
47°F
Mostly Cloudy
Flood Warning
Flood Warning issued April 18 at 3:56PM CDT until April 18 at 11:31PM CDT by NWS Milwaukee/Sullivan WI
Flood Warning
Flood Warning issued April 18 at 3:56PM CDT by NWS Milwaukee/Sullivan WI
Destination
Late night in Cooperstown on Tuesday
Local time
3:54 AM
CDT
Current temp
41°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Scenic Trail
The Ice Age National Scenic Trail spans 1,200 miles, traverses some of Wisconsin's finest geologic and glacial features, and passes through the ancestral lands of 15 Tribes. The Trail is built, manage...
Park data from the National Park Service API. Alerts update every 2 hours.
You'll spend most of your time on the interstate, with 91% of the 221 miles on highways like I-90 and I-41. The longest continuous stretch on a single highway is 62.5 miles on I-90. Expect to transition to surface roads, specifically State Highway 82, for the final portion of your drive. This means you'll likely notice a shift from higher-speed interstate cruising to more local traffic and potentially more frequent intersections as you approach Cooperstown.
This is a straightforward highway drive that stays mostly on I 90 and I 41. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 69.6 miles in.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 22 significant decision points across 221 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 69.6 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 151.7 miles: Complex interchange - multiple decisions in a short stretch; at 151.9 miles (I 41; US 41): Merge point - match speed before joining. Lane positioning matters here.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between La Crosse, WI and Cooperstown, WI, road signs point toward Oxford and Appleton.
Oxford
Appleton
Founded 1842
La Crosse is a city in the Coulee Region of Southwest Wisconsin on the Mississippi River. It is the county seat of La Crosse County. It's nestled between the river and picturesque bluffs that rise behind it. With a city population of around 50,000 and the metropolitan area just under 100,000, La Crosse offers visitors plenty of activities to do and sights to see, without the overwhelming hustle and bustle of bigger cities.
Top landmarks
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 4h 47m. Total distance: 221 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 47m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (91%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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