Origin
Independence, MO
Night in Independence on Saturday
Local time
9:44 PM
CDT
Current temp
73°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
4h 7m
Distance
213.7 mi
344 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$33
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Independence, MO
Wikimedia Commons
Cottleville, MO
Wikimedia Commons
This 213.7-mile journey from Independence to Cottleville is manageable in about 4 hours and 7 minutes, making it a perfect one-day trip. You'll primarily be on the Dwight D. Eisenhower Highway and U.S. Submarine Veterans' Memorial Highway, with a portion on MO 364. The estimated fuel cost for this drive is around $33. Given its relatively short duration and location entirely within the Midwest region of Missouri, it's a straightforward route for a single day's travel. You'll encounter one recommended stop along the way.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
106.9 miles from Independence, MO
A natural place for your longest stop of the day , about 1h 58m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Dwight D. Eisenhower Highway | 135.3 mi | 2h 34m |
| U.S. Submarine Veterans' Memorial Highway | 54.4 mi | 58m |
| MO 364 | 4.2 mi | 5m |
| Avenue of the Saints | 4.1 mi | 4m |
| MO N | 3.4 mi | 6m |
| South Noland Road | 3.1 mi | 5m |
| Truman/Eisenhower Presidential Highway | 2.6 mi | 3m |
| Sheriff Roger I. Wilson Memorial Highway | 1.9 mi | 2m |
Step-by-step road directions between Independence, MO and Cottleville, MO.
Start on East Kansas Avenue
Turn right onto South Lynn Street
Turn left onto East Walnut Street
Turn right onto South Noland Road
Turn left
Merge onto I 70
Continue on I 70
Continue on I 70
Continue on I 70; US 40
Keep slight left at fork onto I 70
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Continue on I 70; US 40
Take the exit onto US 40
Merge onto I 64; US 40; US 61
Take the exit
Merge onto MO 364
Take the exit
Keep slight left at fork
Turn slight left onto MO K
Turn right onto MO N
Continue on MO N
Turn right onto Oak Street
Turn left onto Main Street
Arrive at destination
With a total duration of just over 4 hours, you have the flexibility to depart at your convenience. Leaving in the morning will give you ample time to reach Cottleville without feeling rushed, and you can utilize the single recommended stop for a break. Keep an eye on your fuel levels, especially during the 135.3-mile stretch on the Dwight D. Eisenhower Highway, as services might be less frequent. This route is best tackled in one go, but if you prefer a more leisurely pace, a brief overnight stay could be considered, though it's not strictly necessary.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 47 miles or 53m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 106.9 miles or 1h 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 18m
Traffic, exits, and arrival timing usually matter more near Cottleville, MO than in the middle of the route.
Open the route before leaving Independence, MO so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Independence, MO
This is one driving day of about 213.7 miles and 4h 7m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
107 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 47 miles helps settle the day before fatigue starts building.
The midpoint is around 106.9 miles from Independence, MO, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Dwight D. Eisenhower Highway if your tank is already low. That segment runs about 135.3 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 3.3 and 210 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn left toward I 70 East: Columbia, Saint Louis
Multiple destination signs - pick the right one
Take the exit onto US 40 toward I 64 East, US 40 East, US 61 South: Chesterfield
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Take the exit toward MO 364 East
Exit ramp - move to the correct lane early. Lane positioning matters here
Take the exit toward MO K
Exit ramp - move to the correct lane early. Lane positioning matters here
Keep slight left at fork toward MO K North
Highway fork - watch signs carefully. Lane positioning matters here
Regular Gas
$33.41 one way
$66.82 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $36.68 | $73.36 |
| premium | $4.89 | $41.12 | $82.25 |
| diesel | $5.61 | $47.18 | $94.36 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$33
Meals
$25–$50
Total
$58–$83
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 74.8 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $22 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 64.1 | 0 | $22.44 | $10.26 |
| Efficient EV | 53.4 | 0 | $18.70 | $8.55 |
| EV Truck/SUV | 85.5 | 1 | $29.92 | $13.68 |
Gas CO2
75 kg
EV CO2
25 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Night in Independence on Saturday
Local time
9:44 PM
CDT
Current temp
73°F
Unavailable
Destination
Night in Cottleville on Saturday
Local time
9:44 PM
CDT
Current temp
57°F
Unavailable
74°F
Columbia, MO
107 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Park data from the National Park Service API. Alerts update every 2 hours.
Expect a "turn-heavy local drive" for this route, with a highway share of 2 out of 5. While you'll spend time on major highways, the profile suggests frequent changes in direction and road type. The longest uninterrupted stretch you'll experience is 135.3 miles, providing a good period of consistent travel before the route becomes more involved. This means you'll likely transition between faster highway driving and more local road navigation as you progress toward Cottleville.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 3.3 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 14 significant decision points across 213.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 3.3 miles: Multiple destination signs - pick the right one; at 200.8 miles (US 40): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 205.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Weekend Trip
Doable as a same-day drive at 4h 7m. Total distance: 213.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 7m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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