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Trip from Hollister, MO to Saint Peters, MO

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Jul 19, 2026 · Editorial standards

Drive Time

4h 54m

Distance

249.7 mi

402 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$37

one way

EV Charging

Unknown

Best Time to Leave

Save up to 41 min
4 AM
4h 41m ★
6 AM
4h 55m
8 AM
5h 22m
10 AM
5h 4m
12 PM
5h 2m
3 PM
5h 6m
5 PM
5h 21m
8 PM
4h 47m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Hollister, MO, MO

Hollister, MO

MART PRODUCTION

city in Missouri

Saint Peters, MO

Wikimedia Commons

Trip Overview

Hollister, MO to Saint Peters, MO is 249.7 miles and takes about 4h 54m via I 44, with a fuel budget near $44 and enough daylight to finish in a day. This trip stays within the Midwest region, making it a straightforward connection between two points in Missouri. With an 81% highway share, you'll spend most of your time on major interstates. It's a single-day trip, so plan your departure to maximize daylight and minimize traffic. This route is ideal if you're looking for efficiency and a direct path.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

124.9 miles from Hollister, MO

A natural place for your longest stop of the day , about 2h 22m into the drive .

Main Roads

Road Distance Duration
I 44 170.3 mi 3h 3m
American Legion Memorial Highway 18.6 mi 21m
Manchester Road 13.4 mi 18m
US Highway 65 12 mi 13m
Schoolcraft Freeway 10.7 mi 13m
MO 109 4.9 mi 7m
Mid Rivers Mall Drive 4.7 mi 9m
MO 94 3.4 mi 4m
Longest stretch: I 44 — 170.3 mi, about 3h 3m

Traffic on I-44

Hour-of-day weekday pattern from 8 FHWA count stations on your route.

Peak

4 PM

~1,432 veh/hr typical · worst 1,709

Quietest

2 AM

~177 veh/hr

Peak-to-quiet ratio

8.1×

busier at peak than in the quiet hours

12a 6a noon 6p 11p

Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).

Turn-by-Turn Driving Directions

Step-by-step road directions between Hollister, MO and Saint Peters, MO.

1

Start on Old Mill Road

392 ft · 22 sec · Old Mill Road
2

Turn left onto Esplanade Drive

385 ft · 24 sec · Esplanade Drive
3

Turn left onto US 65 Bus

1.2 mi · 2 min · South Business 65
4

Enter roundabout onto US 65 Bus; MO 76

372 ft · 7 sec · US 65 Bus; MO 76
Toward US 65 Business, MO 76 West: Branson
5

Continue on US 65 Bus; MO 76

0.7 mi · 1 min · US 65 Bus; MO 76
Toward US 65 Business, MO 76 West: Branson
6

Continue on Red Route

0.4 mi · 46 sec · Veterans Boulevard
7

Continue on Red Route

150 ft · 3 sec · Veterans Boulevard
8

Enter roundabout onto Red Route

287 ft · 8 sec · Branson Landing Boulevard
9

Continue on Red Route

0.5 mi · 58 sec · Branson Landing Boulevard
10

Take the ramp

0.2 mi · 29 sec
Toward US 65 North: Springfield
11

Merge onto US 65; MO 76

7.7 mi · 8 min · American Legion Memorial Highway
12

Continue on US 65

12 mi · 13 min · US Highway 65
13

Continue on US 65

11 mi · 12 min · American Legion Memorial Highway
14

Continue on US 65

11 mi · 13 min · Schoolcraft Freeway
Use the straight / slight right lanes.
15

Take the exit

0.6 mi · 54 sec
Toward I 44 East: Saint Louis
16

Merge onto I 44

170 mi · 3 hr 3 min · I 44
17

Take the exit

0.2 mi · 27 sec
Exit 253 Toward I 44 Business, MO 100 East: Gray Summit Use the slight right lane.
18

Turn left onto MO 100

13 mi · 18 min · Manchester Road
Use the straight lane.
19

Take the exit

0.2 mi · 30 sec
Toward MO 109
20

Enter roundabout onto MO 109

224 ft · 4 sec · MO 109
21

Continue on MO 109

515 ft · 10 sec · MO 109
22

Enter roundabout onto MO 109

98 ft · 1 sec · MO 109
23

Continue on MO 109

0.4 mi · 45 sec · MO 109
24

Enter roundabout onto MO 109

94 ft · 2 sec · MO 109
25

Continue on MO 109

4.3 mi · 6 min · MO 109
26

Enter roundabout onto South Eatherton Road

94 ft · 1 sec · South Eatherton Road
27

Continue on South Eatherton Road

2.4 mi · 4 min · South Eatherton Road
28

Continue on Olive Street Road

0.9 mi · 1 min · Olive Street Road
29

Take the ramp onto Chesterfield Airport Road

0.7 mi · 1 min · Chesterfield Airport Road
30

Merge onto I 64; US 40; US 61

2.7 mi · 3 min · Avenue of the Saints
Use the straight lane.
31

Take the exit

0.2 mi · 15 sec
Exit 10 Toward MO 94: Defiance, Saint Charles Use the slight right lane.
32

Keep slight right at fork

313 ft · 4 sec
Toward MO 94 East: Saint Charles Use the right lane.
33

Merge onto MO 94

3.4 mi · 4 min · MO 94
Use the right lane.
34

Keep slight right at fork

0.2 mi · 22 sec
Toward Mid Rivers Mall Drive, Pitman Hill Road Use the straight / slight right lanes.
35

Turn left onto Mid Rivers Mall Drive

4.7 mi · 9 min · Mid Rivers Mall Drive
Use the left / straight lanes.
36

Take the ramp

0.3 mi · 20 sec
Toward I 70 West: Wentzville Use the slight left lane.
37

Merge onto I 70

479 ft · 6 sec · I 70
38

Arrive at destination

I 70

Trip Plan

Given the 4h 54m duration, departing in the morning is recommended to avoid late-day fatigue and potential evening traffic. The $44 fuel cost is an estimate, so be sure to factor in current prices. You have one main road, I 44, for the majority of the trip, so keeping an eye on its mile markers will help you gauge your progress. Since this is a single-day drive, you have flexibility; consider a brief stop around the halfway point, perhaps near the 170.3-mile stretch on I 44, to stretch your legs before the final push to Saint Peters.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 124.9 miles from Hollister, MO, or about 2h 22m into the drive.
The longest continuous stretch on this route runs about 170.3 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 55 miles or 1h 7m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 124.9 miles or 2h 22m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 48m

Traffic, exits, and arrival timing usually matter more near Saint Peters, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving Hollister, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Hollister, MO

This is one driving day of about 249.7 miles and 4h 54m.

Your first comfortable stop window is around 55 miles from Hollister, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 44 for about 170.3 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Cuba, MO, MO

Mid-route town

Meal stop

Cuba, MO

125 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Battlefield, MO

Fuel and coffee

A short stop after about 55 miles helps settle the day before fatigue starts building.

Dixon, MO

Meal break

The midpoint is around 124.9 miles from Hollister, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 44 if your tank is already low. That segment runs about 170.3 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Stops Along Your Drive

Picked by where they fit in your drive — first break, midpoint reset, final stretch.

Saint Clair Rest Area (Westbound)

0.1 mi from route

TA

0.1 mi from route

Flying J Travel Center

0.1 mi from route

Road Ranger

0.1 mi from route

Mr. Fuel

0.1 mi from route

QuikTrip

0.1 mi from route

Truck Parking

0.1 mi from route

Truck Parking

0.1 mi from route

Saint Clair Rest Area (Eastbound)

0.1 mi from route

Buc-ee's

0.1 mi from route

ONE9 Travel Center

0.1 mi from route

Love's Travel Stop

0.2 mi from route

B&D Auto/Truck Plaza

0.2 mi from route

Conway Rest Area (Eastbound)

0.2 mi from route

Conway Rest Area (Westbound)

0.2 mi from route

Love's Travel Stop

0.2 mi from route

QuikTrip

0.2 mi from route

TA

0.3 mi from route

Rest Area

0.9 mi from route

Pilot Travel Center

1.9 mi from route

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 25

5 decision points cluster between mile 1.3 and 244.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

7
1.3 mi into trip | ~3m in | US 65 Bus; MO 76

Enter roundabout onto US 65 Bus; MO 76 toward US 65 Business, MO 76 West: Branson

Roundabout - know your exit number before entering. Multiple destination signs - pick the right one

Toward US 65 Business, MO 76 West: Branson
8
215.4 mi into trip | ~4h in

Take the exit toward I 44 Business, MO 100 East: Gray Summit

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 253 Toward I 44 Business, MO 100 East: Gray Summit
8
240.7 mi into trip | ~4h 39m in

Take the exit toward MO 94: Defiance, Saint Charles

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 10 Toward MO 94: Defiance, Saint Charles
8
240.9 mi into trip | ~4h 39m in

Keep slight right at fork toward MO 94 East: Saint Charles

Highway fork - watch signs carefully. Lane positioning matters here

Use the right lane. Toward MO 94 East: Saint Charles
8
244.4 mi into trip | ~4h 44m in

Keep slight right at fork toward Mid Rivers Mall Drive, Pitman Hill Road

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Toward Mid Rivers Mall Drive, Pitman Hill Road

Fuel & Cost

Regular Gas

$36.87 one way

$73.75 round trip

$3.75/gal 25.4 MPG avg 87 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.14 $40.71 $81.42
premium $4.72 $46.36 $92.72
diesel $4.80 $47.15 $94.30

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$37

Meals

$25–$50

Total

$62–$87

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 87.4 kg one way. Prices: EIA weekly data, 2026-07-13.

Driving Electric?

About $26 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 74.9 0 $26.22 $11.99
Efficient EV 62.4 0 $21.85 $9.99
EV Truck/SUV 99.9 1 $34.96 $15.98

Gas CO2

87 kg

EV CO2

29 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Jul 18, 2026

Origin

Hollister, MO

Late night in Hollister on Sunday

Local time

5:21 AM

CDT

Current temp

93°F

Slight Chance Showers And Thunderstorms

SW 2 to 8 mph 19% chance Live forecast

Heat Advisory

Heat Advisory issued July 18 at 4:25AM CDT until July 18 at 8:00PM CDT by NWS Memphis TN

Heat Advisory

Heat Advisory issued July 18 at 3:04AM CDT until July 21 at 7:00PM CDT by NWS St Louis MO

Destination

Saint Peters, MO

Late night in Saint Peters on Sunday

Local time

5:21 AM

CDT

Current temp

75°F

Mostly Clear

SW 5 mph 2% chance Live forecast

Heat Advisory

Heat Advisory issued July 18 at 4:25AM CDT until July 18 at 8:00PM CDT by NWS Memphis TN

Heat Advisory

Heat Advisory issued July 18 at 3:04AM CDT until July 21 at 7:00PM CDT by NWS St Louis MO

89°F

Cuba, MO

125 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

18 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 54m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Wilson's Creek National Battlefield

Wilson's Creek National Battlefield

National Battlefield

Wilson's Creek was the first major Civil War battle fought west of the Mississippi River, and where the first Union general was killed in action. The costly Southern victory on August 10, 1861, focuse...

10 mi from route ~24 min detour Free near mile 34.4
Caution: BE AWARE OF HIGH-WATER DANGER
View on nps.gov
Gateway Arch National Park

Gateway Arch National Park

National Park

Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...

25 mi from route ~63 min detour $19 near mile 232.5
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

You'll be on the highway for about 81% of this drive, covering 202.2 miles on main roads like I 44 and American Legion Memorial Highway. The longest uninterrupted stretch is 170.3 miles on I 44, offering a good chance for steady cruising. The transition from highway to surface roads like Manchester Road will occur later in the trip, likely in the Saint Peters area. Expect a generally rural feel for much of the drive, punctuated by increasing exit density as you approach your destination.

81% highway — fuel and pacing are the main things to plan.
38 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 170.3 mi on I 44.

How Hard Is This Drive?

9/10

This is a straightforward highway drive that stays mostly on I 44 and American Legion Memorial Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 1.3 miles in near US 65 Bus; MO 76.

Driving Effort 9/10

High effort - long or complex enough to need steady focus all day

Balances navigation complexity with total wheel time.

This is a demanding drive. With 25 significant decision points across 249.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 1.3 miles (US 65 Bus; MO 76): Roundabout - know your exit number before entering. Multiple destination signs - pick the right one; at 215.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 240.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Elevation Profile

Gently rolling terrain

1,486 ft 443 ft

Total Climb

833 ft

Total Descent

1,117 ft

Highest Point

1,486 ft

~53.5 mi in

Elevation Range

1,043 ft

About the Cities

Starting in Hollister, MO

Full guide →

Hollister is a small town in Southwest Missouri near Branson.

Top landmarks

  • Downing Street Historic District — historic district in Hollister, Missouri

Arriving in Saint Peters, MO

Full guide →

Founded 1910

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 54m. Total distance: 249.7 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 54m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (81%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 170.3 miles on I 44. The full list of main roads is in the Roads section above.

Yes — we found about 20 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Saint Peters, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 20 rest areas along the route for bathroom stops.

The main spots that need attention: at 1.3 miles (US 65 Bus; MO 76): Roundabout - know your exit number before entering. Multiple destination signs - pick the right one; at 215.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 240.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

Yes — Wilson's Creek National Battlefield and Gateway Arch National Park. See the National Parks section for detour distances and tips on detours.

Possible but tiring. At 4.9 hours each way, an in-and-out day trip would put you behind the wheel for 9.8 hours — manageable with a long break at Saint Peters, MO, but most travelers stay overnight.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.

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