Origin
Henderson, NY
Late night in Henderson on Tuesday
Local time
4:09 AM
EDT
Current temp
43°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
6h 51m
Distance
336.4 mi
541 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$55
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Henderson, NY
Renan Tagliaferro
This 336.4-mile journey from Henderson, NY to Hempstead, NY is designed for a single day of travel, taking approximately 6 hours and 51 minutes. Primarily utilizing I-81 and I-380, this route offers a highway-focused experience, making it a straightforward drive. With an estimated fuel cost of $55, it's an economical option for traversing the Northeast region. While there's one recommended stop, the longest continuous stretch on I-81 spans 183.9 miles, so plan your breaks accordingly to ensure comfort on this direct trip.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
168.2 miles from Henderson, NY
A natural place for your longest stop of the day , about 3h 21m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 81 | 183.9 mi | 3h 37m |
| Keystone Shortway | 80 mi | 1h 37m |
| I 380 | 23.6 mi | 25m |
| State Route 178 | 8.7 mi | 12m |
| Cross Bronx Expressway | 6.6 mi | 8m |
| Christopher Columbus Highway | 5.5 mi | 5m |
| Clearview Expressway | 5 mi | 5m |
| I 84 | 3.7 mi | 4m |
Step-by-step road directions between Henderson, NY and Hempstead, NY.
Start on County Road 72
Continue on NY 178
Take the ramp
Merge onto I 81
Keep slight right at fork onto I-81
Continue on I 81
Continue on I-81
Continue on I 81
Keep slight right at fork onto I 81
Keep slight right at fork onto US 6
Continue on I 84; I 380
Keep slight right at fork onto I 380
Keep slight left at fork
Merge onto I 80
Keep slight right at fork onto I 80
Keep slight left at fork
Keep slight right at fork
Turn right
Turn straight onto CR 56
Continue on CR 56
Continue on CR 56
Take the ramp
Merge onto US 1; US 9; US 46
Take the exit
Merge onto I 95 EXPR
Keep slight left at fork onto I 95 EXPR
Continue on I 95; US 1; US 9
Continue on I 95; US 1
Continue on I 95; US 1
Keep slight right at fork onto I 295
Merge onto I 295
Continue on I 295
Continue on I 295
Turn left onto NY 25
Turn right onto NY 25
Turn left onto NY 25
Continue on NY 25
Turn slight right onto Tulip Avenue
Turn right onto New Hyde Park Road
Turn left onto NY 24
Turn slight right onto NY 102
Turn right onto Greenwich Street
Turn left onto Peninsula Boulevard
Arrive at destination
To make the most of this 6-hour, 51-minute drive, consider an early morning departure from Henderson, NY to avoid potential traffic as you approach Hempstead, NY. With a total distance of 336.4 miles, breaking it up with just one stop is feasible, but be mindful of the 183.9-mile segment on I-81 – that's a good point to consider your first break. Keep an eye on your fuel levels, as the estimated cost is $55, and plan your refueling accordingly. This route is well-suited for a single-day push, so you have the flexibility to depart when you feel most rested.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 74 miles or 1h 30m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 168.2 miles or 3h 21m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 29m
Traffic, exits, and arrival timing usually matter more near Hempstead, NY than in the middle of the route.
Open the route before leaving Henderson, NY so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Henderson, NY
This is one driving day of about 336.4 miles and 6h 51m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
168 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 74 miles helps settle the day before fatigue starts building.
The midpoint is around 168.2 miles from Henderson, NY, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 81 if your tank is already low. That segment runs about 183.9 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 141.1 and 318.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Keep slight right at fork onto I 81 toward I 81 South: Scranton
Highway fork - watch signs carefully. Lane positioning matters here
Keep slight right at fork onto US 6 toward I 84 East, I 380 South, US 6 East: Carbondale, Mt Pocono
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 95 North: George Washington Bridge, New York City
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork toward Leonia, Teaneck
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork onto I 295 / Cross Bronx Expressway toward I 295 South: Throgs Neck Bridge
Highway fork - watch signs carefully. Lane positioning matters here
Regular Gas
$55.37 one way
$110.75 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.52 | $59.88 | $119.75 |
| premium | $4.92 | $65.20 | $130.40 |
| diesel | $5.61 | $74.27 | $148.55 |
Estimated Tolls: $22.73
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$55
Tolls
$23
Meals
$25–$50
Total
$103–$128
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 117.7 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $35 in charging · 1 stop · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 100.9 | 1 | $35.32 | $16.15 |
| Efficient EV | 84.1 | 0 | $29.43 | $13.46 |
| EV Truck/SUV | 134.6 | 1 | $47.10 | $21.53 |
Gas CO2
118 kg
EV CO2
39 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Henderson on Tuesday
Local time
4:09 AM
EDT
Current temp
43°F
Unavailable
Destination
Late night in Hempstead on Tuesday
Local time
4:09 AM
EDT
Current temp
83°F
Partly Sunny
63°F
Ramapo, NY
168 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Expect a predominantly highway-focused drive, with 71% of the 336.4 miles on major interstates like I-81 and I-380. The route features a significant uninterrupted stretch of 183.9 miles on I-81, indicating long periods of consistent speed. While the Keystone Shortway offers a change of pace, the overall character leans towards efficient travel rather than winding scenic byways. This drive is about covering ground effectively, with the road primarily serving as a conduit between your start and end points.
This is a straightforward highway drive that stays mostly on I 81 and Keystone Shortway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 141.1 miles in near I 81.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 28 significant decision points across 336.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 141.1 miles (I 81): Highway fork - watch signs carefully. Lane positioning matters here; at 194.4 miles (US 6): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 309 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Henderson, NY and Hempstead, NY, road signs point toward Mt Pocono, Milford, New York City, Leonia, Teaneck and George Washington Bridge Upper Level.
Mt Pocono
Milford
New York City
Leonia
Teaneck
George Washington Bridge Upper Level
Hempstead is the most populous town in America, with a whopping 700,000 residents, located on the South Shore of Nassau County, New York. The town is highly urbanized and fragmented, containing 22 semi-autonomous villages within its boundaries, and forty other neighborhoods. Garden City, encompassing the "Nassau Hub" region, has its own article. The other prominent communities in Hempstead include Floral Park, Hempstead Village, Valley Stream, Rockville Centre, Freeport, Merrick, and the Five Towns area.
Top landmarks
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 6h 51m. Total distance: 336.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 51m drive, plan rest stops for pacing.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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