Hazelwood, MO to O'Fallon, MO is 20.1 miles and takes about 29m via I 70, with a fuel budget near $3 and enough daylight to finish in a day. This short trip stays within the Midwest region, making it a simple transition between two Missouri locations. It’s a straightforward drive, primarily on major roadways, ideal for a quick commute or a brief excursion. Given its brevity, it’s perfectly suited for a same-day trip, allowing ample time for activities at your destination. Consider this route when you need to cover a short distance efficiently without venturing far from familiar territory.