Origin
Harrisburg, PA
Morning in Harrisburg on Sunday
Local time
6:38 AM
EDT
Current temp
64°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
3h 29m
Distance
155.2 mi
250 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$26
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Middletown, PA
Michael Taccetta
Harrisburg to Middletown is 155.2 miles and takes about 3h 29m via US 220, with a fuel budget near $26 and enough daylight to finish in a day. This trip stays within Pennsylvania, traversing the Northeast region on a drive that mixes highway travel with more local roads. It's a manageable distance, perfect for a single-day excursion. You'll encounter a varied landscape as you make your way north, offering a pleasant change of scenery without demanding an overnight stay. Consider this route if you're looking for a straightforward journey with a clear destination.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
77.6 miles from Harrisburg, PA
A natural place for your longest stop of the day , about 1h 46m into the drive .
| Road | Distance | Duration |
|---|---|---|
| US 220 | 53 mi | 1h 1m |
| Susquehanna Trail | 28.4 mi | 38m |
| North Cameron Street | 14.3 mi | 20m |
| I 180 | 12.4 mi | 13m |
| North Berwick Turnpike | 11.9 mi | 20m |
| Central Susquehanna Valley Thruway | 11.3 mi | 12m |
| Selinsgrove Bypass | 10.3 mi | 17m |
| Roosevelt Highway | 6.5 mi | 9m |
Step-by-step road directions between Harrisburg, PA and Middletown, PA.
Start on North 7th Street
Enter roundabout onto North 7th Street
Continue on North 7th Street
Turn right onto Maclay Street
Turn left onto US 22
Take the exit
Merge onto US 11; US 15
Continue on US 11; US 15
Take the exit
Merge onto PA 147
Continue on I 180
Take the exit
Turn right onto PA 405
Turn left onto PA 405
Continue on US 220
Take the exit
Merge onto US 6
Continue on US 6
Continue on US 6
Turn right onto North Berwick Turnpike
Arrive at destination
Given the relatively short duration of about 3.5 hours, you have plenty of flexibility for when to depart. Leaving in the morning allows ample time for any unscheduled stops or to simply enjoy the drive without feeling rushed. With only one main stop suggested by the data, you'll want to ensure you have enough fuel before setting out, as the longest stretch without potential services could be significant. Pay attention to road signs as you transition between US 220 and the more local roads like the Susquehanna Trail to avoid any confusion. The $26 fuel cost estimate provides a good baseline for budgeting.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 34 miles or 49m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 77.6 miles or 1h 46m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 47m
Traffic, exits, and arrival timing usually matter more near Middletown, PA than in the middle of the route.
Open the route before leaving Harrisburg, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Harrisburg, PA
This is one driving day of about 155.2 miles and 3h 29m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
78 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 34 miles helps settle the day before fatigue starts building.
The midpoint is around 77.6 miles from Harrisburg, PA, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 0 and 135.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Enter roundabout onto North 7th Street
Roundabout - know your exit number before entering
Take the exit toward US 11 North, US 15 North: Selinsgrove, Williamsport
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Merge onto US 11; US 15 / Susquehanna Trail
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward PA 405: Muncy, Hughesville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Take the exit toward US 6: Troy, Towanda
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Regular Gas
$25.73 one way
$51.46 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $28.18 | $56.36 |
| premium | $4.93 | $30.10 | $60.20 |
| diesel | $5.61 | $34.27 | $68.53 |
Estimated Tolls: $1.62
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$26
Tolls
$2
Meals
$25–$50
Total
$52–$77
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 54.3 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $16 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 46.6 | 0 | $16.30 | $7.45 |
| Efficient EV | 38.8 | 0 | $13.58 | $6.21 |
| EV Truck/SUV | 62.1 | 0 | $21.73 | $9.93 |
Gas CO2
54 kg
EV CO2
18 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Harrisburg on Sunday
Local time
6:38 AM
EDT
Current temp
64°F
Unavailable
Destination
Morning in Middletown on Sunday
Local time
6:38 AM
EDT
Current temp
40°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
This drive offers a mixed experience, with 52% of the route being highway. You'll experience a substantial uninterrupted stretch of 53 miles on US 220, providing a good opportunity to settle into a steady pace. As you travel, the roads will transition, likely moving from faster-paced highway sections to the more deliberate pace of local arteries like the Susquehanna Trail and North Cameron Street. Expect a dynamic drive that keeps you engaged, rather than a monotonous interstate cruise. The profile suggests a journey that evolves as you progress towards your destination.
This route mixes highway mileage with some local-road sections near the start or finish. You will hit about 13 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near North 7th Street.
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 155.2 miles you will encounter 13 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (North 7th Street): Roundabout - know your exit number before entering; at 15.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 16 miles (US 11; US 15 / Susquehanna Trail): Merge point - match speed before joining. Lane positioning matters here.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Harrisburg, PA and Middletown, PA, road signs point toward Williamsport, Hughesville and Towanda.
Williamsport
Hughesville
Towanda
Harrisburg is the capital and 4th-largest metropolitan area of Pennsylvania, with a metro population of 592,000 people in 2020. Harrisburg is known as the host city of the Pennsylvania Farm Show, the largest free indoor agriculture exposition in the United States, the largest annual outdoor sports show in North America, an auto show, which features a large static display of new and classic cars, and Motorama, a two-day event consisting of a car show, motocross racing, and remote control car racing.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 3h 29m. Total distance: 155.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 29m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (52%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Harrisburg, PA or browse trips ending in Middletown, PA.
Looking for more statewide routes? Browse PA road trips.