Traveling from Fredericktown to St. Louis covers 89 miles of Missouri terrain, a trip that typically takes about 1 hour and 30 minutes. Since this journey is relatively short, it is perfectly suited for a single-day excursion. You should budget approximately $13 for fuel to complete the transit between these two Midwestern locations. Because the drive is straightforward, you won't need to worry about booking overnight accommodations unless you plan to extend your stay in the city. It is a practical, efficient connection that links the local charm of Fredericktown directly to the urban environment of St. Louis.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
44.4 miles from Fredericktown, MO
A natural place for your longest stop of the day
, about 53m into the drive
.
Main Roads
Road
Distance
Duration
US 67
51.9 mi
59m
I 55
20.5 mi
22m
Rosa Parks Highway
12.5 mi
15m
South Tucker Boulevard
1.3 mi
3m
West Main Street
1.2 mi
2m
US 67 Business
0.4 mi
<1m
Gravois Avenue
0.2 mi
<1m
Market Street
<0.1 mi
<1m
Longest stretch:
US 67
— 51.9 mi, about 59m
Turn-by-Turn Driving Directions
Step-by-step road directions between Fredericktown, MO and St. Louis, MO.
1
Start on East Main Street
44 ft·2 sec·East Main Street
2
Enter roundabout onto West Main Street
270 ft·8 sec·West Main Street
3
Continue on West Main Street
1.2 mi·2 min·West Main Street
4
Enter roundabout onto US 67 Business; MO 72
155 ft·2 sec·US 67 Business; MO 72
5
Continue on US 67 Business; MO 72
0.3 mi·38 sec·US 67 Business; MO 72
6
Take the ramp
0.3 mi·32 sec
Toward US 67 North: Farmington
7
Merge onto US 67
52 mi·59 min·US 67
8
Keep slight right at fork onto US 67
0.3 mi·27 sec·US 67
9
Take the exit
0.3 mi·49 sec
Toward I 55 North: Saint Louis
10
Merge onto I 55
21 mi·22 min·I 55
11
Continue on I 55
12 mi·15 min·Rosa Parks Highway
Use the straight / slight right lanes.
12
Take the exit
0.2 mi·23 sec
Exit 207AToward MO 30 East: Gravois AvenueUse the slight right lane.
13
Turn slight right onto Gravois Avenue
0.2 mi·27 sec·Gravois Avenue
14
Continue on South Tucker Boulevard
1.3 mi·3 min·South Tucker Boulevard
15
Turn right onto Market Street
86 ft·2 sec·Market Street
16
Arrive at destination
Market Street
Trip Plan
Given the 1 hour and 30 minute duration, you have plenty of flexibility when planning your departure time. Since there are zero scheduled stops, you can easily complete the entire 89-mile distance in one sitting without needing to pace yourself for long-haul fatigue. Keep in mind that the turn-heavy nature of this path means your actual travel time might fluctuate slightly based on local traffic patterns within the towns you pass through. It is wise to verify your fuel levels before leaving Fredericktown, as the $13 estimate assumes a steady transit. Use the absence of highway driving to your advantage by enjoying the local pace, but stay alert for frequent turns as you navigate off the main streets.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 44.4 miles from Fredericktown, MO, or about 53m into the drive.
The longest continuous stretch on this route runs about 51.9 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 20 miles or 24m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 44.4 miles or 53m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 28m
Traffic, exits, and arrival timing usually matter more near St. Louis, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Fredericktown, MO so your first major turns are already loaded.
Day 1
Settle into the route from Fredericktown, MO
This is one driving day of about 88.8 miles and 1h 47m.
Your first comfortable stop window is around 20 miles from Fredericktown, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 67 for about 51.9 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 9
5 decision points cluster between mile 0 and 87.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
0 mi into trip|~0m in|West Main Street
Enter roundabout onto West Main Street
Roundabout - know your exit number before entering
4
1.2 mi into trip|~2m in|US 67 Business; MO 72
Enter roundabout onto US 67 Business; MO 72
Roundabout - know your exit number before entering
4
53.4 mi into trip|~1h 3m in|US 67
Keep slight right at fork onto US 67
Highway fork - watch signs carefully
4
53.8 mi into trip|~1h 3m in
Take the exit toward I 55 North: Saint Louis
Exit ramp - move to the correct lane early
Toward I 55 North: Saint Louis
7
87.1 mi into trip|~1h 42m in
Take the exit toward MO 30 East: Gravois Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 207A
Toward MO 30 East: Gravois Avenue
Fuel & Cost
Regular Gas
$13.88 one way
$27.77 round trip
$3.97/gal25.4 MPG avg31 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$15.24
$30.49
premium
$4.89
$17.09
$34.18
diesel
$5.61
$19.61
$39.21
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$14
Meals
$25–$50
Total
$39–$64
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 31.1 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $9 in charging
· 0 stops
· 68% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
26.6
0
$9.32
$4.26
Efficient EV
22.2
0
$7.77
$3.55
EV Truck/SUV
35.5
0
$12.43
$5.68
Gas CO2
31 kg
EV CO2
10 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Fredericktown, MO
Late night
in Fredericktown on Sunday
Local time
1:04 AM
CDT
Current temp
54°F
Unavailable
Live forecast
Destination
St. Louis, MO
Late night
in St. Louis on Sunday
Local time
1:04 AM
CDT
Current temp
58°F
Chance Rain Showers then Partly Sunny
NW 9 to 16 mph43% chanceLive forecast
56°F
Crystal City, MO
44 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
4 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 47m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Gateway Arch National Park
National Park
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
Established by 1750, Ste. Geneviève was the first permanent European settlement in Missouri. Early French Canadian settlers were drawn here by the rich agricultural land known as Le Grand Champ (the B...
25 mi from route
~61 min detour
Free
near mile 39.8
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a turn-heavy local drive rather than a monotonous interstate haul for this 89-mile trek. You will be navigating through local corridors like Court Square and West Main Street, as the route features zero percent highway travel. Because there is no highway share, the longest uninterrupted stretch on Court Square is effectively zero miles, requiring your full attention behind the wheel. The road’s personality is defined by these technical, shifting segments that demand a more hands-on approach than a standard freeway cruise. You will experience a consistent rhythm of turns as you transition from the local streets of Fredericktown toward your destination.
82% highway — fuel and pacing are the main things to plan.
16 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 51.9 mi on US 67.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on US 67 and I 55. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near West Main Street.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 47m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (West Main Street): Roundabout - know your exit number before entering; at 1.2 miles (US 67 Business; MO 72): Roundabout - know your exit number before entering; at 53.4 miles (US 67): Highway fork - watch signs carefully.
The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic Mississippi and Missouri rivers. And capping it all is the world's tallest man-made monument, the beautiful and iconic Gateway Arch.
St. Louis is a city of culture and surprisingly inexpensive. Among American cities, only Washington, D.C. has more free attractions for tourists and residents alike. Hotels, restaurants, and even parking garages avoid the premium pricing common in other big cities. Although often overlooked, St. Louis can be an affordable, educational, and fun family getaway.
The longest stretch is about 51.9 miles on US 67. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: near the start (West Main Street): Roundabout - know your exit number before entering; at 1.2 miles (US 67 Business; MO 72): Roundabout - know your exit number before entering; at 53.4 miles (US 67): Highway fork - watch signs carefully.
Yes — Gateway Arch National Park and Ste. Geneviève National Historical Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at St. Louis, MO before heading back.
