Doniphan, MO to New York, MO is 376.9 miles and takes about 7h 55m via US 63, with a fuel budget near $59 and enough daylight to finish in a day. This trip stays within the Midwest, entirely within Missouri, so you won't encounter significant regional shifts. Expect a mostly highway experience for the bulk of this drive, making it a straightforward option if you're looking for efficiency. With only two recommended stops, it's a route designed for getting from point A to point B without extensive detours, suitable for a single-day commitment.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
188.5 miles from Doniphan, MO
A natural place for your longest stop of the day
, about 4h 13m into the drive
.
Main Roads
Road
Distance
Duration
US 63
135.7 mi
2h 40m
Chicago-Kansas City Expressway
79.6 mi
1h 31m
MO 19
54.4 mi
1h 15m
US 60
36.4 mi
42m
MO 72
24.3 mi
31m
MO 21
22.4 mi
33m
North Bishop Avenue
12.9 mi
15m
MO B
3.5 mi
8m
Longest stretch:
US 63
— 135.7 mi, about 2h 40m
Turn-by-Turn Driving Directions
Step-by-step road directions between Doniphan, MO and New York, MO.
1
Start on Plum Street
169 ft·9 sec·Plum Street
2
Turn right onto MO 142
0.7 mi·1 min·Walnut Street
3
Turn right onto US 160; MO 21
2.0 mi·2 min·US 160; MO 21
4
Continue on MO 21
22 mi·33 min·MO 21
5
Turn left onto US 60; MO 21
36 mi·42 min·US 60; MO 21
6
Turn right onto MO 19
13 mi·18 min·MO 19
7
Turn slight right onto MO 19
42 mi·56 min·MO 19
8
Turn left onto MO 32; MO 72
1.5 mi·2 min·MO 32; MO 72
9
Turn right onto MO 72
24 mi·31 min·MO 72
10
Turn right onto Salem Avenue
0.7 mi·1 min·Salem Avenue
11
Turn right onto Holloway Street
0.9 mi·2 min·Holloway Street
Use the straight / right lanes.
12
At end of road, turn left onto East 18th Street
0.2 mi·36 sec·East 18th Street
13
Continue on North Walnut Street
0.1 mi·29 sec·North Walnut Street
14
Turn right onto I 44 Business; US Historic 66; US 63
13 mi·15 min·North Bishop Avenue
Use the right lane.
15
Continue on US 63; MO 28
48 mi·1 hr 2 min·US 63; MO 28
16
Take the exit onto US 63
0.3 mi·40 sec·US 63
Toward US 54 East, US 63 North: Fulton, Columbia
17
Merge onto US 54; US 63
1.4 mi·1 min·US 54; US 63
18
Take the exit onto US 63
87 mi·1 hr 37 min·US 63
Toward US 63 North: ColumbiaUse the straight lane.
19
Take the exit
0.2 mi·11 sec
Toward US 36 West, MO 110 West: Saint Joseph
20
Merge onto US 36; MO 110
80 mi·1 hr 31 min·Chicago-Kansas City Expressway
21
Turn left onto MO B
3.5 mi·8 min·MO B
22
Arrive at destination
MO B
Trip Plan
To make the most of this 7h 55m drive, aim for an early morning departure from Doniphan to maximize daylight. With 376.9 miles to cover, you'll have about two hours of driving between stops, so plan your breaks accordingly. The $59 fuel estimate is based on current averages, but it's always wise to check prices as you go. Keep an eye on your fuel gauge, especially as you approach the end of the longest stretch on US 63, as services can become less frequent.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 188.5 miles from Doniphan, MO, or about 4h 13m into the drive.
The longest continuous stretch on this route runs about 135.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 83 miles or 1h 51m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 188.5 miles or 4h 13m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 41m
Traffic, exits, and arrival timing usually matter more near New York, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Doniphan, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Doniphan, MO
This is one driving day of about 376.9 miles and 7h 55m.
Your first comfortable stop window is around 83 miles from Doniphan, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on US 63 for about 135.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 142.5 and 293.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
142.5 mi into trip|~3h 12m in|Holloway Street
Turn right onto Holloway Street
Lane positioning matters here
Use the straight / right lanes.
6
143.6 mi into trip|~3h 16m in|I 44 Business; US Historic 66; US 63 / North Bishop Avenue
Turn right onto I 44 Business; US Historic 66; US 63 / North Bishop Avenue
Lane positioning matters here
Use the right lane.
5
205.1 mi into trip|~4h 34m in|US 63
Take the exit onto US 63 toward US 54 East, US 63 North: Fulton, Columbia
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 54 East, US 63 North: Fulton, Columbi...
6
206.8 mi into trip|~4h 37m in|US 63
Take the exit onto US 63 toward US 63 North: Columbia
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight lane.
Toward US 63 North: Columbia
7
293.7 mi into trip|~6h 14m in
Take the exit toward US 36 West, MO 110 West: Saint Joseph
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 36 West, MO 110 West: Saint Joseph
Fuel & Cost
Regular Gas
$55.66 one way
$111.32 round trip
$3.75/gal25.4 MPG avg132 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.14
$61.45
$122.89
premium
$4.72
$69.98
$139.96
diesel
$4.80
$71.17
$142.33
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$56
Meals
$25–$50
Total
$81–$106
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 131.9 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $40 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
113.1
1
$39.57
$18.09
Efficient EV
94.2
1
$32.98
$15.08
EV Truck/SUV
150.8
1
$52.77
$24.12
Gas CO2
132 kg
EV CO2
44 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 17, 2026
Origin
Doniphan, MO
Late night
in Doniphan on Saturday
Local time
4:16 AM
CDT
Current temp
72°F
Partly Cloudy
W 2 mph3% chanceLive forecast
Destination
New York, MO
Late night
in New York on Saturday
Local time
4:16 AM
CDT
Current temp
72°F
Partly Cloudy
SSW 2 mph5% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Very similar conditions
Both ends of the route are sitting at about the same temperature right now.
Road read
7h 55m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This drive is primarily on highways, with 95% of the route utilizing them. You'll experience 135.7 miles on US 63 as the longest continuous stretch on a single road. The transition to surface roads will occur late in the drive, after extensive highway cruising. Expect a consistent flow of traffic typical of major expressways for most of your travel time.
95% highway — fuel and pacing are the main things to plan.
22 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 135.7 mi on US 63.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on US 63 and Chicago-Kansas City Expressway. You will hit about 16 points where you need to pay attention to lane position or signs. The trickiest moment comes around 142.5 miles in near Holloway Street.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 376.9 miles you will encounter 16 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 142.5 miles (Holloway Street): Lane positioning matters here; at 143.6 miles (I 44 Business; US Historic 66; US 63 / North Bishop Avenue): Lane positioning matters here; at 205.1 miles (US 63): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Elevation Profile
Gently rolling terrain
1,229 ft398 ft
Total Climb
1,214 ft
Total Descent
812 ft
Highest Point
1,229 ft
~107.7 mi in
Elevation Range
830 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Doniphan, MO to New York, MO, road signs begin pointing toward Columbia along the way.
Doable as a same-day drive at 7h 55m. Total distance: 376.9 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 55m drive, plan rest stops for pacing.
First-Time Driver
Mostly highway driving (95%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 135.7 miles on US 63. The full list of main roads is in the Roads section above.
Yes — we found about 4 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This is a long drive, so arriving tired and in the dark compounds. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at New York, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. There are 4 rest areas along the route for bathroom stops.
The main spots that need attention: at 142.5 miles (Holloway Street): Lane positioning matters here; at 143.6 miles (I 44 Business; US Historic 66; US 63 / North Bishop Avenue): Lane positioning matters here; at 205.1 miles (US 63): Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.
Not recommended in a single day. At 7.9 hours each way, a round trip means 15.8 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at New York, MO before the return drive.
