Trip from Denison, TX to San Antonio, TX
Pin this tripCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Jul 19, 2026 · Editorial standards
Drive Time
6h 16m
Distance
347.9 mi
560 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$48
one way
EV Charging
Unknown
Best Time to Leave
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Denison, TX
Wikimedia Commons
San Antonio, TX
Wikimedia Commons
Trip Overview
Denison, TX to San Antonio, TX is 347.9 miles and takes about 6h 16m via I 35, with a fuel budget near $55 and enough daylight to finish in a day. You'll be traveling within the Great Plains region for the entire trip, staying within Texas. This route is primarily highway driving, making it a straightforward option for a single-day trip. Expect a consistent pace for most of the drive, with a budget-friendly fuel cost. Consider this if you need to cover ground efficiently between these two Texas cities.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
173.9 miles from Denison, TX
A natural place for your longest stop of the day , about 3h 7m into the drive .
Main Roads
| Road | Distance | Duration |
|---|---|---|
| Purple Heart Trail | 99.6 mi | 1h 46m |
| South R L Thornton Freeway | 89.9 mi | 1h 32m |
| I 35 | 55.8 mi | 58m |
| North Central Expressway | 45.7 mi | 49m |
| North Pan Am Expressway | 17 mi | 20m |
| North Sam Rayburn Freeway | 12 mi | 12m |
| North Collins Freeway | 10.1 mi | 10m |
| North Jack Kultgen Expressway | 6.6 mi | 7m |
Traffic on I-35
Hour-of-day weekday pattern from 48 FHWA count stations on your route.
Peak
5 PM
~4,090 veh/hr typical
Quietest
2 AM
~671 veh/hr
Peak-to-quiet ratio
6.1×
busier at peak than in the quiet hours
Averaged across 51 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Denison, TX and San Antonio, TX.
Start on this road
Turn left onto US 69
Continue on Spur 503
Take the exit
Keep slight right at fork
Turn straight onto TX 91
Turn right onto FM 691
Turn left onto North Sam Rayburn Freeway
Take the ramp
Merge onto US 75
Continue on US 75
Continue on US 75
Take the exit
Continue on North Central Expressway
Turn right onto Elm Street
Turn left onto North Pearl Expressway
Turn right onto Young Street
Turn left onto South Harwood Street
Turn right onto Canton Street
Take the ramp
Keep slight left at fork
Keep slight left at fork
Keep slight left at fork
Continue on I 35E
Continue on I 35E
Continue on I 35; US 77
Continue on I 35
Keep slight left at fork onto I 35
Keep slight left at fork onto I 35; US 290
Continue on I 35
Continue on I 35
Continue on I 35
Keep slight left at fork onto I 35
Keep slight left at fork onto I 35
Take the exit
Turn straight onto East Elmira Street
Turn left onto North Main Avenue
Enter roundabout onto Navarro Street
Continue on Navarro Street
Keep slight right at fork onto North Main Avenue
Turn right onto West Travis Street
Turn left onto North Flores Street
Continue on Military Plaza
Turn left onto Dolorosa Street
Arrive at destination
Trip Plan
Given the 6h 16m estimated drive time, leaving Denison, TX in the morning should allow you to reach San Antonio with plenty of daylight to spare. The 347.9-mile distance is manageable for a single day, so you don't need to plan an overnight stop unless you prefer a more relaxed pace. Keep an eye on your fuel levels, especially during the longest stretch of 99.6 miles on Purple Heart Trail, and budget around $55 for gas. There's one recommended stop, so plan to stretch your legs and refuel midway if needed.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 77 miles or 1h 27m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 173.9 miles or 3h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 7m
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Before You Leave
Open the route before leaving Denison, TX so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Denison, TX
This is one driving day of about 347.9 miles and 6h 16m.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
174 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
A short stop after about 77 miles helps settle the day before fatigue starts building.
The midpoint is around 173.9 miles from Denison, TX, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Purple Heart Trail if your tank is already low. That segment runs about 99.6 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Stops Along Your Drive
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Service Plaza
Hill County Northbound Rest Area
Buc-ee's
QuikTrip
Buc-ee's
Flying J Travel Center
Walburg Travel Center & Food Court
Love's Travel Stop
Love's Travel Stop
Petro Stopping Centers
Buc-ee's
Service Plaza
QuikTrip
Ascent Travel Center
TA
Flying J Travel Plaza
Pilot Travel Center
Hill County Southbound Rest Area
QuikTrip
Road Ranger
Flying J Travel Center
Marlstone Retail Center
Love's Travel Stop
Love's Travel Stop
Buc-ee's
Pilot Travel Center
TA
Service Plaza
Bell County Southbound Rest Area
QuikTrip
Minuteman Press
Love's Travel Stop
SoPac Trail Rest Area
Pilot Travel Center
Service Plaza
Petro Stopping Centers
Pilot Travel Center
Spanish Governor's Palace
Near the end, right off the route
San Antonio, Texas
Hours: 9 am–5 pm
+12102077527
Visit websiteGO RIO San Antonio River Cruises
Near the end, right off the route
San Antonio, Texas
Hours: 10 am–10 pm
+12102274746
Visit websiteSan Antonio | The Saga
Near the end, right off the route
San Antonio, Texas
Hours: 9–9:30 pm
+12102259800
Visit websiteHemisfair
Near the end, right off the route
San Antonio, Texas
Hours: 5 am–12 pm
+12107094750
Visit websiteSan Antonio Fire Museum
Near the end, right off the route
San Antonio, Texas
Hours: 10 am–3:30 pm
+12103907236
Visit websiteThe Amazing Mirror Maze
Near the end, right off the route
San Antonio, Texas
Hours: 10:30 am–8 pm
+12102242288
Visit websiteCity Park
Early in the drive, right off the route
Dallas, Texas
Hours: 10 am–5 pm
+19724823055
Visit websiteSEA LIFE San Antonio
Near the end, right off the route
San Antonio, Texas
Hours: 10 am–5 pm
+12106101160
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 305 decision points cluster between mile 73.6 and 346.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the exit toward Downtown, Good-Latimer Expressway
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork toward I 35E North, I 35E South: Denton, Waco
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork onto I 35; US 290 / Purple Heart Trail toward 32nd Street, Dean Keeton Street
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight left at fork onto I 35 / North Pan Am Expressway toward I 35 South: Lower Level, Laredo
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward Lexington Avenue, Main Avenue, San Pedro Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Fuel & Cost
Regular Gas
$47.65 one way
$95.30 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $3.89 | $53.23 | $106.45 |
| premium | $4.23 | $57.87 | $115.74 |
| diesel | $4.80 | $65.69 | $131.38 |
Estimated Tolls: $3.65
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$48
Tolls
$4
Meals
$25–$50
Total
$76–$101
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 121.7 kg one way. Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $37 in charging · 1 stop · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 104.4 | 1 | $36.53 | $16.70 |
| Efficient EV | 87 | 0 | $30.44 | $13.92 |
| EV Truck/SUV | 139.2 | 1 | $48.71 | $22.27 |
Gas CO2
122 kg
EV CO2
41 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Origin
Denison, TX
Morning in Denison on Sunday
Local time
10:25 AM
CDT
Current temp
90°F
Mostly Sunny
Flash Flood Warning
Flash Flood Warning issued July 17 at 6:02AM CDT until July 17 at 9:00AM CDT by NWS San Angelo TX
Flash Flood Warning
Flash Flood Warning issued July 17 at 5:03AM CDT until July 17 at 7:00AM CDT by NWS San Angelo TX
Destination
San Antonio, TX
Morning in San Antonio on Sunday
Local time
10:25 AM
CDT
Current temp
90°F
Partly Sunny
Flash Flood Warning
Flash Flood Warning issued July 17 at 6:02AM CDT until July 17 at 9:00AM CDT by NWS San Angelo TX
Flash Flood Warning
Flash Flood Warning issued July 17 at 5:03AM CDT until July 17 at 7:00AM CDT by NWS San Angelo TX
96°F
Troy, TX
174 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
Very similar conditions
Both ends of the route are sitting at about the same temperature right now.
Road read
6h 16m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Waco Mammoth National Monument
National Monument
Standing as tall as 14 feet and weighing 20,000 pounds, Columbian mammoths roamed across what is present-day Texas thousands of years ago. Today, the fossil specimens represent the nation's first and...
San Antonio Missions National Historical Park
National Historical Park
Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...
Park data from the National Park Service API. Alerts update every 2 hours.
What kind of drive is this?
About 70% of this 347.9-mile route is highway. You'll encounter a longest stretch of 99.6 miles on Purple Heart Trail before transitioning to other roads. Expect a mostly highway profile, which means you'll likely see a good number of exits and merges as you pass through various towns and cities. The latter portion of your drive will involve more surface roads.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on Purple Heart Trail and South R L Thornton Freeway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 73.6 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 30 significant decision points across 347.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 73.6 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 75.7 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 266.3 miles (I 35; US 290 / Purple Heart Trail): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
Total Climb
627 ft
Total Descent
708 ft
Highest Point
776 ft
~24.8 mi in
Elevation Range
319 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Denison, TX and San Antonio, TX, road signs point toward Downtown, Denton, Waco and Dallas Zoo.
Downtown
Denton
Waco
Dallas Zoo
About the Cities
Starting in Denison, TX
Full guide →Founded 1872
Denison is in the Blackland Prairie region.
Top landmarks
- • Eisenhower Birthplace State Historic Site — building in Denison, Grayson County, Texas
Arriving in San Antonio, TX
Full guide →Founded 1718
San Antonio is the second largest city in the state of Texas and the 7th largest in the United States. It's the 24th largest metropolitan area in the country. Visited by more than 31 million annual visitors, San Antonio is a beautiful city at the axis of three different geological terrains: Hill Country, South Texas Plains and Prairie and Lakes. There's a lot to do in this city: fine art museums, historical missions and plenty of amusement parks in addition to great dining and lots of drinking. The culture and people are vibrant and interesting. San Antonio's downtown is one of the most lively in the nation.
Top landmarks
- • Alamo Mission in San Antonio — historic place in San Antonio, Bexar County, Texas
- • San Antonio Missions National Historical Park — historic district in San Antonio, Bexar County, Texas
- • Fort Sam Houston — military base in San Antonio, Texas
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 6h 16m. Total distance: 347.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 16m drive, plan rest stops for pacing.
Frequently Asked Questions
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, NPS for national parks, and FHWA TMAS for hourly traffic volumes. See our methodology for refresh cadence and limitations.
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