Trip from Anthony, TX to San Antonio, TX

Pin this trip

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards

Drive Time

9h 20m

Distance

572.2 mi

921 km

Drive Score

8/10

Great drive

Same Day?

2-day trip

Fuel Cost

$86

one way

EV Charging

Unknown

Best Time to Leave

Save up to 25 min

4 AM

9h 12m ★

6 AM

9h 20m

8 AM

9h 37m

10 AM

9h 26m

12 PM

9h 25m

3 PM

9h 27m

5 PM

9h 36m

8 PM

9h 15m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Best Time Drive vs Fly

Google Maps Waze Apple Maps

Download GPX

Anthony, TX

Dani Islas

San Antonio, TX

Wikimedia Commons

Trip Overview

Spanning 572.5 miles across the Texas landscape, this journey from Anthony to San Antonio takes approximately 8 hours and 28 minutes of pure driving time. Because of the significant distance, we recommend breaking this trip into two days to ensure you stay alert and enjoy the transition across the Great Plains. You should budget about $85 for fuel to cover the full trek. Relying on local routes like South 1st Street, Franklin Street, and Antonio Street rather than major interstates defines this path. It is a substantial commitment that requires careful pacing to avoid fatigue, making it better suited for an overnight itinerary than a single-day push.

Trip Pace

Best split across 2 days

Treat the return leg as its own travel day rather than an afterthought.

Break Rhythm

2 planned breaks

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

286.1 miles from Anthony, TX

A natural place for your longest stop of the day , about 4h 43m into the drive .

Main Roads

Road	Distance	Duration
I 10	555.7 mi	8h 57m
Camino Real de Tierra Adentro	11.6 mi	13m
McDermott Freeway	1.7 mi	2m
Franklin Street	0.8 mi	1m
North Pecos-La Trinidad	0.7 mi	1m
Antonio Street	0.5 mi	1m
Dolorosa Street	0.5 mi	<1m
South 1st Street	<0.1 mi	<1m

Longest stretch: I 10 — 555.7 mi, about 8h 57m

Turn-by-Turn Driving Directions

Step-by-step road directions between Anthony, TX and San Antonio, TX.

Start on Jefferson Street

75 ft · 5 sec · Jefferson Street

Turn right onto South 1st Street

259 ft · 16 sec · South 1st Street

Turn left onto FM 1905

0.8 mi · 1 min · Franklin Street

Continue on FM 1905

0.5 mi · 1 min · Antonio Street

Turn right onto South Desert Boulevard

172 ft · 4 sec · South Desert Boulevard

Take the ramp

0.1 mi · 19 sec

Merge onto I 10; US 85; US 180

12 mi · 13 min · Camino Real de Tierra Adentro

Use the straight / slight right lanes.

Continue on I 10; US 180

175 mi · 2 hr 53 min · I 10; US 180

Use the straight / slight right lanes.

Keep slight right at fork onto I 10

363 mi · 5 hr 44 min · I 10

Use the straight / slight right lanes.

Keep slight right at fork onto I 10; US 87

17 mi · 19 min · I 10; US 87

Use the straight / slight right lanes.

Keep slight right at fork onto I 10; US 87

1.7 mi · 2 min · McDermott Freeway

Take the exit

0.5 mi · 1 min

Exit 569C Toward Santa Rosa Street, Downtown Use the slight right lane.

Turn straight onto North Pecos-La Trinidad

0.2 mi · 16 sec · North Pecos-La Trinidad

Keep slight right at fork onto North Pecos-La Trinidad

0.6 mi · 1 min · North Pecos-La Trinidad

Use the straight lane.

Turn left onto Dolorosa Street

0.5 mi · 55 sec · Dolorosa Street

Use the straight / left lanes.

Arrive at destination

Dolorosa Street

Trip Plan

To manage the 572.5-mile distance effectively, plan for at least two intentional stops to stretch your legs and refuel. Since you are navigating local roads rather than high-speed highways, account for potential fluctuations in travel time that might exceed the base estimate of 8 hours and 28 minutes. Setting aside $85 for gas is a solid baseline, but keeping a little extra in your travel budget is a smart move for longer stints. We suggest splitting the trip into two days to keep your arrival in San Antonio stress-free. A helpful tip for this specific route is to verify your navigation settings to ensure you remain on the designated local thoroughfares of South 1st, Franklin, and Antonio streets throughout the journey.

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

This drive is better paced as a 2-day trip.

Plan roughly 2 meaningful breaks for fuel, food, and rest.

The halfway point lands around 286.1 miles from Anthony, TX, or about 4h 43m into the drive.

The longest continuous stretch on this route runs about 555.7 miles.

Consider an overnight stop or starting very early.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 126 miles or 2h 8m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 286.1 miles or 4h 43m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Overnight split

Day 1 wrap after about 286.1 miles or 4h 43m

Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.

Final approach

Final hour starts around 8h 17m

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

Open the route before leaving Anthony, TX so your first major turns are already loaded.

Leave with enough water and a charging cable within reach, not packed away.

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Pick one backup stop option before the midpoint in case traffic changes your pacing.

Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.

Day 1

Settle into the route from Anthony, TX

Aim for roughly 286 miles and 4.7 hours of wheel time on this day.

Day 2

Finish the approach into San Antonio, TX

Aim for roughly 286 miles and 4.7 hours of wheel time on this day.

Your first comfortable stop window is around 126 miles from Anthony, TX.

This route usually feels better as a 2-day drive than as one long push.

Plan about 2 real breaks rather than only quick fuel stops.

The longest stretch is on I 10 for about 555.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

First major stop

Coffee and fuel

Van Horn, TX

189 mi into the route

Best for: Coffee, fuel, and an easy first stretch

This is a natural early stop once the first hours of the drive are behind you.

city in and county seat of Kimble County, Texas, United States

Second major stop

Overnight candidate

Junction, TX

378 mi into the route

Best for: Hotel check-in, dinner, and a fresh start

This lines up well with a realistic day-end stop if you are breaking the drive into stages.

Find hotels in Junction, TX

Overnight Options

Night 1

McCamey, TX

286 mi · about 4.7h in

A practical overnight split lands near McCamey, TX after about 286 miles or 4.7 hours of driving.

Find hotels

Pacing Suggestions

Van Horn, TX

Fuel and coffee

A short stop after about 126 miles helps settle the day before fatigue starts building.

Big Lake, TX

Meal break

The midpoint is around 286.1 miles from Anthony, TX, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 10 if your tank is already low. That segment runs about 555.7 miles.

Overnight split

Hours: 9 am–10 pm

+12102271373

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 11

5 decision points cluster between mile 188 and 571.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

188 mi into trip | ~3h 10m in | I 10

Keep slight right at fork onto I 10

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes.

551.4 mi into trip | ~8h 55m in | I 10; US 87

Keep slight right at fork onto I 10; US 87

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight / slight right lanes.

570.5 mi into trip | ~9h 16m in

Take the exit toward Santa Rosa Street, Downtown

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Exit 569C Toward Santa Rosa Street, Downtown

571.2 mi into trip | ~9h 18m in | North Pecos-La Trinidad

Keep slight right at fork onto North Pecos-La Trinidad

Highway fork - watch signs carefully. Lane positioning matters here

Use the straight lane.

571.7 mi into trip | ~9h 19m in | Dolorosa Street

Turn left onto Dolorosa Street

Lane positioning matters here

Use the straight / left lanes.

Fuel & Cost

Regular Gas

$86.46 one way

$172.92 round trip

$3.84/gal 25.4 MPG avg 200 kg CO₂

Fuel Type	$/gal	One Way	Round Trip
midgrade	$4.20	$94.64	$189.28
premium	$4.54	$102.16	$204.32
diesel	$5.61	$126.33	$252.67

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$86

Hotel (1n)

$80–$140

Meals

$50–$100

Total

$216–$326

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 200.2 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $60 in charging · 2 stops · 67% less CO₂

Vehicle Type	kWh	Stops	DC Fast	Home Charge
Average EV	171.7	2	$60.08	$27.47
Efficient EV	143.1	1	$50.07	$22.89
EV Truck/SUV	228.9	2	$80.11	$36.62

Gas CO2

200 kg

EV CO2

67 kg (67% less)

Plan for 2 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 16, 2026

Origin

Anthony, TX

Late night in Anthony on Tuesday

Local time

4:57 AM

MDT

Current temp

81°F

Unavailable

Live forecast

Destination

San Antonio, TX

Late night in San Antonio on Tuesday

Local time

5:57 AM

CDT

Current temp

90°F

Partly Sunny

SSE 10 mph 0% chance Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.

Time zone

1 hour later

The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.

Temperature spread

9 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

9h 20m on the road

This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Chamizal National Memorial

National Memorial

Chamizal is more than just an urban park to recreate or enjoy a quiet afternoon. These grounds are a reminder of the harmonious settlement of a 100-year boundary dispute between the United States and...

3 mi from route ~7 min detour Free near mile 19.7

View on nps.gov

San Antonio Missions National Historical Park

National Historical Park

Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...

9 mi from route ~22 min detour Free near mile 572.2

View on nps.gov

Lyndon B Johnson National Historical Park

National Historical Park

Lyndon B. Johnson National Historical Park tells the story of our 36th president beginning with his ancestors until his final resting place on his beloved LBJ Ranch. This entire "circle of life" gives...

28 mi from route ~70 min detour Free near mile 532.7

View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

Expect a unique experience behind the wheel, as this route features 0% highway driving, relying instead on local roads that provide a different perspective of the Texas terrain. Navigating South 1st Street, Franklin Street, and Antonio Street means you will trade high-speed interstate monotony for a slower, more deliberate pace. The road's personality is defined by these local stretches, which demand your full attention and offer a steady rhythm rather than the quick, blurred vistas of a freeway. Since the entire journey stays within the Great Plains, you can anticipate consistent regional geography that unfolds gradually over your 8-hour and 28-minute travel time.

97% highway — fuel and pacing are the main things to plan.

16 navigation steps total — most of the decisions cluster near the start and finish.

Longest single stretch: 555.7 mi on I 10.

How Hard Is This Drive?

7/10

This is a straightforward highway drive that stays mostly on I 10 and Camino Real de Tierra Adentro. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 188 miles in near I 10.

Driving Effort 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 11 significant decision points across 572.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 188 miles (I 10): Highway fork - watch signs carefully. Lane positioning matters here; at 551.4 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 570.5 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.

About the Cities

Starting in Anthony, TX

Full guide →

Arriving in San Antonio, TX

Full guide →

Founded 1718

San Antonio is the second largest city in the state of Texas and the 7th largest in the United States. It's the 24th largest metropolitan area in the country. Visited by more than 31 million annual visitors, San Antonio is a beautiful city at the axis of three different geological terrains: Hill Country, South Texas Plains and Prairie and Lakes. There's a lot to do in this city: fine art museums, historical missions and plenty of amusement parks in addition to great dining and lots of drinking. The culture and people are vibrant and interesting. San Antonio's downtown is one of the most lively in the nation.

Top landmarks

• Alamo Mission in San Antonio — historic place in San Antonio, Bexar County, Texas
• San Antonio Missions National Historical Park — historic district in San Antonio, Bexar County, Texas
• Fort Sam Houston — military base in San Antonio, Texas

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Frequently Asked Questions

The longest stretch is about 555.7 miles on I 10. The full list of main roads is in the Roads section above.

Yes — a 2-day pace is more comfortable than one long haul. A sensible stopping point is after roughly 286 miles on day one.

Yes — we found about 60 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at San Antonio, TX before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. There are 60 rest areas along the route for bathroom stops.

Yes — Chamizal National Memorial, San Antonio Missions National Historical Park and Lyndon B Johnson National Historical Park. See the National Parks section for detour distances and tips on detours.

Not recommended in a single day. At 9.3 hours each way, a round trip means 18.7 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at San Antonio, TX before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

Was this helpful?

Thanks for your feedback!

Your tip has been submitted. Thanks!

/500

Explore More

Continue From San Antonio, TX

Spearman, TX 613.3 mi · 10h 43m Gruver, TX 610.6 mi · 10h 42m El Paso, TX 552.1 mi · 8h 56m Amarillo, TX 506.9 mi · 8h 52m

More trips to San Antonio, TX

Los Angeles, CA 1353.9 mi Vinton, TX 568.2 mi Booker, TX 560.9 mi Homestead Meadows North, TX 551 mi Socorro Mission Number 1 Colonia, TX 536.3 mi Panhandle, TX 535 mi

Escape planner: Anthony, TX Scenic drives in TX

Explore more options from Anthony, TX or browse trips ending in San Antonio, TX.

Looking for more statewide routes? Browse TX road trips.