Anthony, TX to Houston, TX is 765.8 miles and takes about 12 hours 44 minutes via I 10, Anderson Loop, and 90th Infantry Division Highway, with a fuel budget near $111 and enough daylight to finish in a day, though it's best split over two days. This long-haul drive crosses Texas, starting in the Great Plains region and ending in the same region, offering a straightforward path across the state. Given its length, planning for an overnight stop is highly recommended to avoid fatigue. It's a practical route for moving between these two Texas locations.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
3 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
382.9 miles from Anthony, TX
A natural place for your longest stop of the day
, about 6h 15m into the drive
.
Main Roads
Road
Distance
Duration
I 10
694.8 mi
11h 18m
Anderson Loop
25.4 mi
29m
90th Infantry Division Highway
14.9 mi
15m
Camino Real de Tierra Adentro
11.6 mi
13m
Katy Freeway
10.7 mi
13m
Katy Tollway
3.2 mi
4m
Interstate 10 East
0.9 mi
2m
Franklin Street
0.8 mi
1m
Longest stretch:
I 10
— 694.8 mi, about 11h 18m
Traffic on I-10
Hour-of-day weekday pattern from 70 FHWA count stations on your route.
Peak
3 PM
~1,724 veh/hr typical
· worst 2,297
Quietest
2 AM
~230 veh/hr
Peak-to-quiet ratio
7.5×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Anthony, TX and Houston, TX.
1
Start on Jefferson Street
75 ft·5 sec·Jefferson Street
2
Turn right onto South 1st Street
259 ft·16 sec·South 1st Street
3
Turn left onto FM 1905
0.8 mi·1 min·Franklin Street
4
Continue on FM 1905
0.5 mi·1 min·Antonio Street
5
Turn right onto South Desert Boulevard
172 ft·4 sec·South Desert Boulevard
6
Take the ramp
0.1 mi·19 sec
7
Merge onto I 10; US 85; US 180
12 mi·13 min·Camino Real de Tierra Adentro
Use the straight / slight right lanes.
8
Continue on I 10; US 180
175 mi·2 hr 53 min·I 10; US 180
Use the straight / slight right lanes.
9
Keep slight right at fork onto I 10
363 mi·5 hr 44 min·I 10
Use the straight / slight right lanes.
10
Keep slight right at fork onto I 10; US 87
5.4 mi·5 min·I 10; US 87
Use the straight / slight right lanes.
11
Take the exit
0.6 mi·1 min
Exit 556BToward Frontage RoadUse the slight right lane.
12
Turn straight onto Interstate 10 West
0.5 mi·54 sec·Interstate 10 West
13
Turn left onto North Loop 1604 West
0.4 mi·43 sec·North Loop 1604 West
Use the straight lane.
14
Take the ramp
0.1 mi·13 sec
Toward Loop 1604 East
15
Merge onto Loop 1604
25 mi·29 min·Anderson Loop
Use the straight / slight right lanes.
16
Turn left onto Interstate 10 East
0.9 mi·2 min·Interstate 10 East
17
Take the ramp
0.2 mi·20 sec
18
Merge onto I 10; US 90; TX 130
15 mi·15 min·90th Infantry Division Highway
Use the straight / slight right lanes.
19
Continue on I 10; TX 130
151 mi·2 hr 34 min·I 10; TX 130
Toward I 10 East: Houston, Austin, WacoUse the straight / slight right lanes.
20
Take the exit
0.3 mi·22 sec
Toward I 10 Toll: Katy TollwayUse the slight left lane.
21
Merge onto I 10 Toll
3.2 mi·4 min·Katy Tollway
22
Take the exit
0.2 mi·15 sec
Use the straight / slight right lanes.
23
Merge onto I 10; US 90
11 mi·13 min·Katy Freeway
Use the slight left lane.
24
Take the exit
0.4 mi·52 sec
Exit 769AToward Downtown, Theatre DistrictUse the straight / slight right lanes.
25
Continue on Smith Street
0.1 mi·29 sec·Smith Street
26
Turn left onto Preston Street
331 ft·16 sec·Preston Street
27
Turn left onto Louisiana Street
179 ft·5 sec·Louisiana Street
28
Arrive at destination
Louisiana Street
Trip Plan
For this 765.8-mile drive, consider departing early in the morning to make good progress. With a total duration of nearly 13 hours, it’s wise to plan for an overnight stop to break up the drive safely. Aim to complete about half the distance on day one, leaving around 380 miles for day two. Keep an eye on your fuel gauge, especially on the longer stretches of I 10, as services can sometimes be spaced out in certain areas. The estimated fuel cost is $111, so budget accordingly.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This drive is better paced as a 2-day trip.
Plan roughly 3 meaningful breaks for fuel, food, and rest.
The halfway point lands around 382.9 miles from Anthony, TX, or about 6h 15m into the drive.
The longest continuous stretch on this route runs about 694.8 miles.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 168 miles or 2h 50m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 382.9 miles or 6h 15m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 382.9 miles or 6h 15m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 11h 39m
Traffic, exits, and arrival timing usually matter more near Houston, TX than in the middle of the route.
Before You Leave
+
Open the route before leaving Anthony, TX so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
+
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from Anthony, TX
Aim for roughly 383 miles and 6.4 hours of wheel time on this day.
Day 2
Finish the approach into Houston, TX
Aim for roughly 383 miles and 6.4 hours of wheel time on this day.
Your first comfortable stop window is around 168 miles from Anthony, TX.
This route usually feels better as a 2-day drive than as one long push.
Plan about 3 real breaks rather than only quick fuel stops.
The longest stretch is on I 10 for about 694.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 21
5 decision points cluster between mile 188 and 765.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
188 mi into trip|~3h 10m in|I 10
Keep slight right at fork onto I 10
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
6
551.4 mi into trip|~8h 55m in|I 10; US 87
Keep slight right at fork onto I 10; US 87
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
7
556.8 mi into trip|~9h in
Take the exit toward Frontage Road
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 556B
Toward Frontage Road
6
557.9 mi into trip|~9h 3m in|North Loop 1604 West
Turn left onto North Loop 1604 West
Lane positioning matters here
Use the straight lane.
8
765.2 mi into trip|~12h 43m in
Take the exit toward Downtown, Theatre District
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 769A
Toward Downtown, Theatre District
Fuel & Cost
Regular Gas
$120.36 one way
$240.71 round trip
$3.99/gal25.4 MPG avg268 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.39
$132.27
$264.53
premium
$4.72
$142.28
$284.55
diesel
$5.60
$168.72
$337.43
Estimated Tolls: $0.23
Katy Tollway
(3.2 mi)$0.23
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$120
Tolls
$0
Hotel (1n)
$80–$140
Meals
$50–$100
Total
$251–$361
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 267.9 kg one way.
Prices: EIA weekly data, 2026-05-18.
Driving Electric?
About $80 in charging
· 2 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
229.7
2
$80.41
$36.76
Efficient EV
191.5
2
$67.01
$30.63
EV Truck/SUV
306.3
3
$107.21
$49.01
Gas CO2
268 kg
EV CO2
90 kg (66% less)
Plan for 2 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of May 25, 2026
Origin
Anthony, TX
Morning
in Anthony on Wednesday
Local time
11:02 AM
MDT
Current temp
63°F
Mostly Cloudy
SE 1 to 5 mph2% chanceLive forecast
Special Weather Statement
Special Weather Statement issued May 24 at 11:27PM CDT by NWS San Angelo TX
Flash Flood Warning
Flash Flood Warning issued May 24 at 10:57PM CDT until May 25 at 1:30AM CDT by NWS Fort Worth TX
Destination
Houston, TX
Afternoon
in Houston on Wednesday
Local time
12:02 PM
CDT
Current temp
72°F
Partly Cloudy
E 5 mph2% chanceLive forecast
Special Weather Statement
Special Weather Statement issued May 24 at 11:27PM CDT by NWS San Angelo TX
Flash Flood Warning
Flash Flood Warning issued May 24 at 10:57PM CDT until May 25 at 1:30AM CDT by NWS Fort Worth TX
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.
Time zone
1 hour later
The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.
Temperature spread
9 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
12h 44m on the road
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Chamizal National Memorial
National Memorial
Chamizal is more than just an urban park to recreate or enjoy a quiet afternoon. These grounds are a reminder of the harmonious settlement of a 100-year boundary dispute between the United States and...
Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...
16 mi from route
~39 min detour
Free
near mile 581
Lyndon B. Johnson National Historical Park tells the story of our 36th president beginning with his ancestors until his final resting place on his beloved LBJ Ranch. This entire "circle of life" gives...
27 mi from route
~67 min detour
Free
near mile 528.2
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route is primarily highway driving, with 92% of the trip on major roads. You'll spend most of your time on I 10, covering a longest stretch of 694.8 miles on this interstate alone. The transition from highway to surface roads will occur near the end of your drive. Expect a consistent driving experience with frequent exits and services available along the main interstate.
92% highway — fuel and pacing are the main things to plan.
28 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 694.8 mi on I 10.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on I 10 and Anderson Loop. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 188 miles in near I 10.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 21 significant decision points across 765.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 188 miles (I 10): Highway fork - watch signs carefully. Lane positioning matters here; at 551.4 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 556.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Elevation Profile
Hilly terrain with moderate elevation changes
4,478 ft35 ft
Total Climb
890 ft
Total Descent
4,657 ft
Highest Point
4,478 ft
~109.4 mi in
Elevation Range
4,443 ft
Notable High Points
4,478 ft at ~109.4 miles+179 ft prominence
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Anthony, TX and Houston, TX, road signs point toward Loop 1604 East, Austin and Waco.
Houston is a sprawling port city in Southeastern Texas. An oil boom and continuing international immigration has brought explosive growth to the city, and it is now the fifth largest metropolitan area in the United States and the most diverse large city since 2021. While at first glance, the city appears to be a 9-5 central business district surrounded by a sea of suburbs and strip malls, there are many hidden gems to be discovered.
Top landmarks
•Museum of Fine Arts, Houston — art museum in Houston, Texas
•Astrodome — historic place in Houston, Harris County, Texas
•Rothko Chapel — building in Houston, Harris County, Texas
The longest stretch is about 694.8 miles on I 10. The full list of main roads is in the Roads section above.
Yes — a 2-day pace is more comfortable than one long haul. A sensible stopping point is after roughly 383 miles on day one.
Expect about $0.23 in tolls one way, starting with Katy Tollway. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
Yes — we found about 81 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Houston, TX before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 3 meaningful breaks. There are 81 rest areas along the route for bathroom stops.
The main spots that need attention: at 188 miles (I 10): Highway fork - watch signs carefully. Lane positioning matters here; at 551.4 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 556.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Yes — Chamizal National Memorial, San Antonio Missions National Historical Park and Lyndon B Johnson National Historical Park. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 12.7 hours each way, a round trip means 25.5 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Houston, TX before the return drive.
