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Trip from Clarksville, TN to Knoxville, TN

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

4h 12m

Distance

225.1 mi

362 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$35

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
3h 59m ★
6 AM
4h 13m
8 AM
4h 39m
10 AM
4h 22m
12 PM
4h 19m
3 PM
4h 23m
5 PM
4h 38m
8 PM
4h 5m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

city in Tennessee, United States

Clarksville, TN

Wikimedia Commons

city and county seat of Knox County, State of Tennessee, United States

Knoxville, TN

Wikimedia Commons

Trip Overview

This 226.6-mile drive from Clarksville, TN to Knoxville, TN is a manageable one-day trip, estimated to take about 3 hours and 27 minutes. With a fuel cost around $34, it's an economical journey. You'll navigate primarily through local roads, as this route has a 0% highway share, meaning it's a turn-heavy local drive. This trip is perfect for a single day, allowing for flexibility in your schedule. Both your starting point in Clarksville and your destination in Knoxville are within the Southeast region, so you won't be crossing major regional boundaries.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

112.5 miles from Clarksville, TN

A natural place for your longest stop of the day , about 2h 8m into the drive .

Main Roads

Road Distance Duration
I 24 119 mi 2h 9m
I 40 96 mi 1h 45m
Madison Street 4.7 mi 8m
TN 76 3.1 mi 3m
Franklin Street 0.3 mi <1m
Henley Street 0.3 mi <1m
University Avenue 0.2 mi <1m
North 2nd Street 0.2 mi <1m
Longest stretch: I 24 — 119 mi, about 2h 9m

Turn-by-Turn Driving Directions

Step-by-step road directions between Clarksville, TN and Knoxville, TN.

1

Start on North 2nd Street

0.2 mi · 27 sec · North 2nd Street
2

Turn left onto Franklin Street

0.3 mi · 52 sec · Franklin Street
3

Turn right onto US 41A

0.2 mi · 29 sec · University Avenue
4

Turn left onto US 41A; SR 76

4.7 mi · 8 min · Madison Street
Use the straight / left / right lanes.
5

Turn left onto TN 76

3.1 mi · 3 min · TN 76
6

Take the exit

0.4 mi · 53 sec
7

Merge onto I 24

33 mi · 35 min · I 24
Use the straight / slight right lanes.
8

Keep slight right at fork onto I 24

2.3 mi · 3 min · I 24
Exit 44A Toward I 24 East, I 65 South: Nashville Use the straight / slight left lanes.
9

Continue on I 24

2.8 mi · 3 min · I 24
Exit 86 Toward I 24 East: Chattanooga, Knoxville Use the straight / slight right lanes.
10

Keep slight left at fork onto I 24

81 mi · 1 hr 27 min · I 24
Exit 50A Toward I 40 East, I 24 East: Knoxville, Chattanooga Use the slight left lane.
11

Continue on I 40

93 mi · 1 hr 42 min · I 40
Use the straight / right lanes.
12

Keep slight left at fork onto I 40

2.9 mi · 3 min · I 40
13

Take the exit

0.4 mi · 27 sec
Exit 388 Toward Convention Center, East Tennessee History Center, Museum of Art
14

Keep slight left at fork

0.5 mi · 56 sec
Exit 388 Toward Convention Center, East Tennessee History Center, Museum of Art
15

Continue on US 441

0.2 mi · 27 sec · Henley Street
Use the straight lane.
16

Continue on US 441

255 ft · 11 sec · Henley Street
17

Arrive at destination

US 441

Trip Plan

Given the drive's duration of just under 3.5 hours and its local road nature, you have the flexibility to leave whenever suits you best, perhaps mid-morning to avoid early rush hours. With only one recommended stop, you can easily manage your breaks. Keep an eye on your fuel gauge, as the estimated cost is $34, and local roads can sometimes lead to slower travel times than anticipated. A specific tip for this route: since it's a turn-heavy local drive, pay close attention to your GPS or navigation app to ensure you don't miss any of the necessary turns, especially as you transition between roads like Franklin Street, University Avenue, and Madison Street.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 112.5 miles from Clarksville, TN, or about 2h 8m into the drive.
The longest continuous stretch on this route runs about 119 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 50 miles or 1h in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 112.5 miles or 2h 8m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 26m

Traffic, exits, and arrival timing usually matter more near Knoxville, TN than in the middle of the route.

Before You Leave

+

Open the route before leaving Clarksville, TN so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Clarksville, TN

This is one driving day of about 225.1 miles and 4h 12m.

Your first comfortable stop window is around 50 miles from Clarksville, TN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 24 for about 119 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in Tennessee, United States

Mid-route town

Meal stop

Cookeville, TN

113 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Cookeville, TN to Knoxville, TN

102.2 mi · 1h 55m

Pacing Suggestions

Nashville, TN

Fuel and coffee

A short stop after about 50 miles helps settle the day before fatigue starts building.

Cookeville, TN

Meal break

The midpoint is around 112.5 miles from Clarksville, TN, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 24 if your tank is already low. That segment runs about 119 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 11

5 decision points cluster between mile 0.7 and 224.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
0.7 mi into trip | ~1m in | US 41A; SR 76 / Madison Street

Turn left onto US 41A; SR 76 / Madison Street

Lane positioning matters here

Use the straight / left / right lanes.
9
42.2 mi into trip | ~50m in | I 24

Keep slight right at fork onto I 24 toward I 24 East, I 65 South: Nashville

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight left lanes. Exit 44A Toward I 24 East, I 65 South: Nashville
9
47.3 mi into trip | ~57m in | I 24

Keep slight left at fork onto I 24 toward I 40 East, I 24 East: Knoxville, Chattanooga

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Exit 50A Toward I 40 East, I 24 East: Knoxville, Chattan...
6
223.9 mi into trip | ~4h 10m in

Take the exit toward Convention Center, East Tennessee History Center, Museum of Art

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 388 Toward Convention Center, East Tennessee Histor...
7
224.3 mi into trip | ~4h 10m in

Keep slight left at fork toward Convention Center, East Tennessee History Center, Museum of Art

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Exit 388 Toward Convention Center, East Tennessee Histor...

Fuel & Cost

Regular Gas

$35.19 one way

$70.38 round trip

$3.97/gal 25.4 MPG avg 79 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $38.64 $77.28
premium $4.89 $43.32 $86.64
diesel $5.61 $49.70 $99.40

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$35

Meals

$25–$50

Total

$60–$85

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 78.8 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $24 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 67.5 0 $23.64 $10.80
Efficient EV 56.3 0 $19.70 $9.00
EV Truck/SUV 90 1 $31.51 $14.41

Gas CO2

79 kg

EV CO2

26 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Clarksville, TN

Late night in Clarksville on Sunday

Local time

5:32 AM

CDT

Current temp

54°F

Unavailable

Live forecast

Destination

Knoxville, TN

Morning in Knoxville on Sunday

Local time

6:32 AM

EDT

Current temp

74°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

1 hour later

The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.

Temperature spread

20 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 12m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Stones River National Battlefield

Stones River National Battlefield

National Battlefield

The Battle of Stones River began on the last day of 1862 and became one of the bloodiest conflicts of the Civil War. The battle produced important military and political gains for the Union, and it ch...

21 mi from route ~52 min detour Free near mile 62.1
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

Prepare for a drive that keeps you engaged with frequent turns; this route is characterized as a 'turn-heavy local drive.' With a 0% highway share, you won't encounter any interstate stretches, ensuring a constant interaction with local roads. The data doesn't specify a longest uninterrupted stretch, but the nature of the route suggests consistent changes in direction and speed. You'll likely experience a dynamic driving experience, moving through various local communities rather than settling into a long, monotonous highway cruise.

97% highway — fuel and pacing are the main things to plan.
17 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 119 mi on I 24.

How Hard Is This Drive?

7/10

This is a straightforward highway drive that stays mostly on I 24 and I 40. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.7 miles in near US 41A; SR 76 / Madison Street.

Driving Effort 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 11 significant decision points across 225.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 0.7 miles (US 41A; SR 76 / Madison Street): Lane positioning matters here; at 42.2 miles (I 24): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 47.3 miles (I 24): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Clarksville, TN to Knoxville, TN, road signs begin pointing toward Chattanooga along the way.

Chattanooga

47.3 mi in | ~57m | via I 24

About the Cities

Arriving in Knoxville, TN

Full guide →

Knoxville, in Knox County, is the third-largest city in Tennessee. It is the home of the University of Tennessee's primary campus (UTK) and site of the 1982 World's Fair.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 12m. Total distance: 225.1 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 12m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (97%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 119 miles on I 24. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Knoxville, TN before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 0.7 miles (US 41A; SR 76 / Madison Street): Lane positioning matters here; at 42.2 miles (I 24): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 47.3 miles (I 24): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Yes — Stones River National Battlefield. See the National Parks section for detour distances and tips on detours.

Possible but tiring. At 4.2 hours each way, an in-and-out day trip would put you behind the wheel for 8.4 hours — manageable with a long break at Knoxville, TN, but most travelers stay overnight.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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