Connecting Yazoo City to Hattiesburg, this 135.3-mile journey is a straightforward trek across Mississippi. You can expect to spend about 2 hours and 51 minutes behind the wheel, making this an ideal candidate for a single-day trip. With a fuel budget of approximately $21, the route is both efficient and budget-friendly. Since the entire drive stays within the Southeast region, you will experience a consistent landscape throughout the trek. Whether you are heading south for business or a change of scenery, the simplicity of the trip allows you to reach your destination without needing an overnight stay.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
67.7 miles from Yazoo City, MS
A natural place for your longest stop of the day
, about 1h 25m into the drive
.
Main Roads
Road
Distance
Duration
Highway 49 South
80.3 mi
1h 37m
US 49
48.6 mi
1h
Old Highway 42
1.8 mi
3m
East Broadway Street
1.4 mi
2m
North Main Street
1.2 mi
2m
I 20
1.2 mi
1m
Grand Avenue
0.3 mi
<1m
North Ward Street
0.2 mi
<1m
Longest stretch:
Highway 49 South
— 80.3 mi, about 1h 37m
Turn-by-Turn Driving Directions
Step-by-step road directions between Yazoo City, MS and Hattiesburg, MS.
1
Start on East 5th Street
64 ft·4 sec·East 5th Street
2
Turn right onto Grand Avenue
0.3 mi·41 sec·Grand Avenue
3
Continue on College Street
0.2 mi·48 sec·College Street
4
At end of road, turn right onto Dunn Avenue
81 ft·5 sec·Dunn Avenue
5
Turn left onto North Ward Street
0.2 mi·56 sec·North Ward Street
6
Turn left onto MS 16; MS 149
1.4 mi·2 min·East Broadway Street
7
Turn right onto US 49; MS 16
36 mi·42 min·US 49; MS 16
8
Take the exit onto US 49
4.9 mi·5 min·US 49
9
Keep slight left at fork onto US 49
3.8 mi·5 min·US 49
10
Merge onto I 20; I 55; US 49
1.1 mi·1 min·I 20; I 55; US 49
11
Keep slight right at fork onto I 20; US 49
347 ft·4 sec·I 20; US 49
Toward Meridian, Hattiesburg
12
Take the exit onto US 49
0.6 mi·42 sec·US 49
Toward Hattiesburg
13
Keep slight right at fork onto US 49
0.7 mi·1 min·US 49
Toward Richland, Hattiesburg
14
Merge onto US 49
80 mi·1 hr 37 min·Highway 49 South
Use the straight lane.
15
Continue on US 49; MS 42
0.4 mi·35 sec·US 49; MS 42
Use the straight lane.
16
Continue on US 49; MS 42
2.4 mi·4 min·US 49; MS 42
Use the straight lane.
17
Turn left onto Old Highway 42
1.8 mi·3 min·Old Highway 42
Use the left lane.
18
Turn right onto North Main Street
1.2 mi·2 min·North Main Street
Use the straight / right lanes.
19
Turn left onto Batson Street
154 ft·8 sec·Batson Street
20
Turn right
329 ft·25 sec
21
At end of road, turn right onto US 11
98 ft·4 sec·East Pine Street
22
Arrive at destination
US 11
Trip Plan
To make the most of this 135.3-mile trip, aim to depart early in the day to avoid peak traffic periods. Given the duration of just under three hours, you should plan for at least one stop to stretch your legs and refuel. Since the route is dominated by a long 80.3-mile stretch on Highway 49 South, ensure your vehicle is prepped for sustained highway speeds before you leave Yazoo City. Keep your budget of $21 for gas in mind when planning your fill-ups along the way. Because this is a short, flexible drive, you have the advantage of choosing your pace without the pressure of a rigid multi-day itinerary.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 67.7 miles from Yazoo City, MS, or about 1h 25m into the drive.
The longest continuous stretch on this route runs about 80.3 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 30 miles or 38m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 67.7 miles or 1h 25m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 17m
Traffic, exits, and arrival timing usually matter more near Hattiesburg, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Yazoo City, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Yazoo City, MS
This is one driving day of about 135.3 miles and 2h 51m.
Your first comfortable stop window is around 30 miles from Yazoo City, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Highway 49 South for about 80.3 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 0 and 49.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0 mi into trip|~0m in|Grand Avenue
Turn right onto Grand Avenue
Navigation decision point
6
0.5 mi into trip|~1m in|Dunn Avenue
At end of road, turn right onto Dunn Avenue
Complex interchange - multiple decisions in a short stretch
6
47.7 mi into trip|~1h in|I 20; US 49
Keep slight right at fork onto I 20; US 49 toward Meridian, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Meridian, Hattiesburg
6
48.4 mi into trip|~1h 1m in|US 49
Keep slight right at fork onto US 49 toward Richland, Hattiesburg
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward Richland, Hattiesburg
5
49.1 mi into trip|~1h 2m in|US 49 / Highway 49 South
Merge onto US 49 / Highway 49 South
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
Fuel & Cost
Regular Gas
$20.43 one way
$40.87 round trip
$3.84/gal25.4 MPG avg47 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$22.43
$44.86
premium
$4.56
$24.28
$48.57
diesel
$5.61
$29.87
$59.75
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$20
Meals
$25–$50
Total
$45–$70
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 47.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $14 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
40.6
0
$14.21
$6.49
Efficient EV
33.8
0
$11.84
$5.41
EV Truck/SUV
54.1
0
$18.94
$8.66
Gas CO2
47 kg
EV CO2
16 kg (66% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Yazoo City, MS
Late night
in Yazoo City on Sunday
Local time
3:11 AM
CDT
Current temp
78°F
Unavailable
Live forecast
Destination
Hattiesburg, MS
Late night
in Hattiesburg on Sunday
Local time
3:11 AM
CDT
Current temp
80°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 51m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This is a highway-focused drive that relies heavily on US 49 and Highway 49 South to move you toward your destination. Roughly 97% of your travel time will be spent on these main arteries, providing a consistent driving experience. You will face a longest uninterrupted stretch of 80.3 miles on Highway 49 South, which requires steady focus. While the route transitions onto Old Highway 42 near the end, the majority of your time is spent on high-speed roads. Expect a functional, direct drive that favors speed and reliability over winding, technical backroads.
97% highway — fuel and pacing are the main things to plan.
22 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 80.3 mi on Highway 49 South.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on Highway 49 South and US 49. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes early in the drive near Grand Avenue.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 135.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: near the start (Grand Avenue): Navigation decision point; at 0.5 miles (Dunn Avenue): Complex interchange - multiple decisions in a short stretch; at 47.7 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
438 ft111 ft
Total Climb
523 ft
Total Descent
469 ft
Highest Point
438 ft
~87 mi in
Elevation Range
327 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Yazoo City, MS and Hattiesburg, MS, road signs point toward Meridian and Richland.
Doable as a same-day drive at 2h 51m. Total distance: 135.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 51m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (97%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 80.3 miles on Highway 49 South. The full list of main roads is in the Roads section above.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Hattiesburg, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: near the start (Grand Avenue): Navigation decision point; at 0.5 miles (Dunn Avenue): Complex interchange - multiple decisions in a short stretch; at 47.7 miles (I 20; US 49): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Hattiesburg, MS before heading back.
