This straightforward, highway-focused drive covers 205.1 miles from Yazoo City, MS, to Gulfport, MS, and is estimated to take about 4 hours and 13 minutes. With 95% of the journey on major roads like US 49 and Highway 49 South, it's an efficient trip that easily fits into a single day. The estimated fuel cost for this route is around $31. You'll be traveling within the Southeast region for the entire trip, moving from one part of Mississippi to another. This route is best suited for those prioritizing getting from point A to point B without extensive detours, making it a practical choice for a day trip.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
102.6 miles from Yazoo City, MS
A natural place for your longest stop of the day
, about 2h 7m into the drive
.
Main Roads
Road
Distance
Duration
US 49
109.7 mi
2h 15m
Highway 49 South
80.3 mi
1h 37m
Lance Corporal Roy M Wheat Memorial Highway
7.7 mi
8m
US 98
3.2 mi
4m
East Broadway Street
1.4 mi
2m
I 20
1.2 mi
1m
Grand Avenue
0.3 mi
<1m
North Ward Street
0.2 mi
<1m
Longest stretch:
US 49
— 109.7 mi, about 2h 15m
Turn-by-Turn Driving Directions
Step-by-step road directions between Yazoo City, MS and Gulfport, MS.
1
Start on East 5th Street
64 ft·4 sec·East 5th Street
2
Turn right onto Grand Avenue
0.3 mi·41 sec·Grand Avenue
3
Continue on College Street
0.2 mi·48 sec·College Street
4
At end of road, turn right onto Dunn Avenue
81 ft·5 sec·Dunn Avenue
5
Turn left onto North Ward Street
0.2 mi·56 sec·North Ward Street
6
Turn left onto MS 16; MS 149
1.4 mi·2 min·East Broadway Street
7
Turn right onto US 49; MS 16
36 mi·42 min·US 49; MS 16
8
Take the exit onto US 49
4.9 mi·5 min·US 49
9
Keep slight left at fork onto US 49
3.8 mi·5 min·US 49
10
Merge onto I 20; I 55; US 49
1.1 mi·1 min·I 20; I 55; US 49
11
Keep slight right at fork onto I 20; US 49
347 ft·4 sec·I 20; US 49
Toward Meridian, Hattiesburg
12
Take the exit onto US 49
0.6 mi·42 sec·US 49
Toward Hattiesburg
13
Keep slight right at fork onto US 49
0.7 mi·1 min·US 49
Toward Richland, Hattiesburg
14
Merge onto US 49
80 mi·1 hr 37 min·Highway 49 South
Use the straight lane.
15
Continue on US 49; MS 42
0.4 mi·35 sec·US 49; MS 42
Use the straight lane.
16
Continue on US 49; MS 42
1.1 mi·1 min·US 49; MS 42
Use the straight lane.
17
Take the exit
0.4 mi·36 sec
Toward I 59 South: New Orleans, Gulf CoastUse the slight right lane.
18
Merge onto I 59
7.7 mi·8 min·Lance Corporal Roy M Wheat Memorial Highway
Toward Mississippi Gulf CoastUse the straight lane.
19
Take the exit onto US 98
3.2 mi·4 min·US 98
Toward US 98 East: Lucedale, MobileUse the straight / slight right lanes.
20
Take the exit
0.3 mi·44 sec
Toward US 49: Wiggins, Gulfport, Mississippi Gulf CoastUse the straight / slight right lanes.
21
Keep slight left at fork
0.2 mi·27 sec
Toward Multi Purpose Center, HattiesburgUse the slight left / slight right lanes.
22
Turn right onto US 49
58 mi·1 hr 9 min·US 49
Use the straight lane.
23
Turn straight onto US 49
4.5 mi·7 min·US 49
Use the left / straight / right lanes.
24
Continue on US 49
215 ft·16 sec·25th Avenue
25
Arrive at destination
US 49
Trip Plan
Given the 4-hour and 13-minute duration, starting your drive in Yazoo City early in the morning is advisable to maximize your day. With only one recommended stop, you have flexibility in pacing yourself, but be aware of the 109.7-mile stretch on US 49 before needing a break. Keep an eye on your fuel levels, especially during longer segments. The estimated fuel cost of $31 is helpful for budgeting. This is a manageable drive for one day, so you won't need to worry about overnight accommodations unless you plan on making extended stops along the way.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 102.6 miles from Yazoo City, MS, or about 2h 7m into the drive.
The longest continuous stretch on this route runs about 109.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 45 miles or 56m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 102.6 miles or 2h 7m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 27m
Traffic, exits, and arrival timing usually matter more near Gulfport, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Yazoo City, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Yazoo City, MS
This is one driving day of about 205.1 miles and 4h 13m.
Your first comfortable stop window is around 45 miles from Yazoo City, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on US 49 for about 109.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 18
5 decision points cluster between mile 0.5 and 142.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
0.5 mi into trip|~1m in|Dunn Avenue
At end of road, turn right onto Dunn Avenue
Complex interchange - multiple decisions in a short stretch
7
130.9 mi into trip|~2h 42m in
Take the exit toward I 59 South: New Orleans, Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 59 South: New Orleans, Gulf Coast
7
139 mi into trip|~2h 51m in|US 98
Take the exit onto US 98 toward US 98 East: Lucedale, Mobile
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 98 East: Lucedale, Mobile
7
142.2 mi into trip|~2h 55m in
Take the exit toward US 49: Wiggins, Gulfport, Mississippi Gulf Coast
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward US 49: Wiggins, Gulfport, Mississippi Gu...
9
142.5 mi into trip|~2h 56m in
Keep slight left at fork toward Multi Purpose Center, Hattiesburg
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left / slight right lanes.
Toward Multi Purpose Center, Hattiesburg
Fuel & Cost
Regular Gas
$30.97 one way
$61.95 round trip
$3.84/gal25.4 MPG avg72 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$34.00
$68.01
premium
$4.56
$36.81
$73.63
diesel
$5.61
$45.28
$90.57
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$31
Meals
$25–$50
Total
$56–$81
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 71.8 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $22 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
61.5
0
$21.54
$9.84
Efficient EV
51.3
0
$17.95
$8.20
EV Truck/SUV
82
1
$28.71
$13.13
Gas CO2
72 kg
EV CO2
24 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Yazoo City, MS
Night
in Yazoo City on Saturday
Local time
11:40 PM
CDT
Current temp
78°F
Unavailable
Live forecast
Destination
Gulfport, MS
Night
in Gulfport on Saturday
Local time
11:40 PM
CDT
Current temp
60°F
Unavailable
Live forecast
58°F
Sumrall, MS
103 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
18 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 13m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a predominantly highway experience on this route, with 95% of the drive utilizing main roads. You'll encounter a significant uninterrupted stretch of 109.7 miles on US 49, offering a consistent pace. The drive is primarily characterized by its highway nature, suggesting a focus on efficient travel rather than winding scenic byways. As you progress, the landscape will gradually shift as you head toward the Gulf Coast, but the road itself remains largely consistent in its highway profile.
95% highway — fuel and pacing are the main things to plan.
25 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 109.7 mi on US 49.
How Hard Is This Drive?
9/10
This is a straightforward highway drive that stays mostly on US 49 and Highway 49 South. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.5 miles in near Dunn Avenue.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 205.1 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.5 miles (Dunn Avenue): Complex interchange - multiple decisions in a short stretch; at 130.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 139 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
407 ft20 ft
Total Climb
451 ft
Total Descent
542 ft
Highest Point
407 ft
~87.9 mi in
Elevation Range
387 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Yazoo City, MS and Gulfport, MS, road signs point toward Meridian, Hattiesburg, Richland, Gulf Coast, Mississippi Gulf Coast and Mobile - among others.
Doable as a same-day drive at 4h 13m. Total distance: 205.1 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 13m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (95%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 109.7 miles on US 49. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Gulfport, MS before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.5 miles (Dunn Avenue): Complex interchange - multiple decisions in a short stretch; at 130.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 139 miles (US 98): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Medgar and Myrlie Evers Home National Monument. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.2 hours each way, an in-and-out day trip would put you behind the wheel for 8.5 hours — manageable with a long break at Gulfport, MS, but most travelers stay overnight.
