Origin
Williamston, SC
Night in Williamston on Saturday
Local time
9:27 PM
EDT
Current temp
74°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 18, 2026 · Editorial standards
Drive Time
5h 1m
Distance
245.8 mi
396 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$38
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Williamston, SC
Connor Scott McManus
Myrtle Beach, SC
Wikimedia Commons
Williamston, SC to Myrtle Beach, SC is 245.8 miles and takes about 5h 1m via I 20 and I 26, with a fuel budget near $38 and enough daylight to finish in a day. This trip stays within South Carolina, moving from the Southeast region to another part of the Southeast. Expect a highway-focused drive that covers a significant portion of the state. It’s a straightforward journey, ideal if you’re looking for an efficient way to get from the western part of South Carolina to the coast. The drive is designed for a single day, making it a convenient option for a quick getaway or a direct transfer.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
122.9 miles from Williamston, SC
A natural place for your longest stop of the day , about 2h 24m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 20 | 79.4 mi | 1h 29m |
| I 26 | 55.2 mi | 1h |
| US 501 Business | 41.9 mi | 55m |
| Golden Strip Freeway | 22.9 mi | 24m |
| West Palmetto Street | 22.6 mi | 32m |
| Highway 418 | 9.9 mi | 14m |
| Highway 8 East | 3.7 mi | 5m |
| SC 576 | 3.1 mi | 3m |
Step-by-step road directions between Williamston, SC and Myrtle Beach, SC.
Start on Spring Park
Turn right onto SC 20
Continue on SC 20
Turn slight left onto SC 20
Continue on SC 20
Turn right onto Courtney Street Extension
At end of road, turn right onto SC 8
Continue on SC 8
Continue on SC 418
Continue on SC 418
Continue on SC 418
Take the ramp
Merge onto I 385
Merge onto I 26
Take the exit
Merge onto I 20
Turn left onto US 76
Continue on SC 576
Continue on US 501 Business; SC 41 Alternate
Turn straight onto US 501
Turn slight right onto 8th Avenue North
Turn right onto US 17 Business
Turn left onto 5th Avenue North
Turn right
Arrive at destination
Given the 5-hour duration, departing in the morning is your best bet to maximize daylight and allow for flexibility. With only one recommended stop, you can choose to power through or take a brief break as needed. Keep an eye on your fuel, as the estimated cost is $38; plan your fill-ups accordingly, especially before longer stretches. For this particular route, consider that the longest uninterrupted drive segment is 79.4 miles, so ensure you’re comfortable with that span before needing a pit stop. Since it’s a single-day trip, you have the advantage of not needing to rush through accommodations.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 54 miles or 1h 7m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 122.9 miles or 2h 24m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h
Traffic, exits, and arrival timing usually matter more near Myrtle Beach, SC than in the middle of the route.
Open the route before leaving Williamston, SC so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Williamston, SC
This is one driving day of about 245.8 miles and 5h 1m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
123 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 54 miles helps settle the day before fatigue starts building.
The midpoint is around 122.9 miles from Williamston, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 20 if your tank is already low. That segment runs about 79.4 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 17.9 and 245.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Merge onto I 385 / Golden Strip Freeway
Merge point - match speed before joining. Lane positioning matters here
Merge onto I 26
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward I 20 East: Florence
Exit ramp - move to the correct lane early. Lane positioning matters here
Merge onto I 20
Merge point - match speed before joining. Lane positioning matters here
Turn right onto US 17 Business / North Kings Highway
Navigation decision point
Regular Gas
$38.44 one way
$76.88 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.34 | $42.03 | $84.06 |
| premium | $4.70 | $45.49 | $90.98 |
| diesel | $5.61 | $54.27 | $108.54 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$38
Meals
$25–$50
Total
$63–$88
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 86 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $26 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 73.7 | 0 | $25.81 | $11.80 |
| Efficient EV | 61.5 | 0 | $21.51 | $9.83 |
| EV Truck/SUV | 98.3 | 1 | $34.41 | $15.73 |
Gas CO2
86 kg
EV CO2
29 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Night in Williamston on Saturday
Local time
9:27 PM
EDT
Current temp
74°F
Unavailable
Destination
Night in Myrtle Beach on Saturday
Local time
9:27 PM
EDT
Current temp
58°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
This route is predominantly highway driving, with 89% of the journey on major roads. You'll spend a good amount of time on interstates, including a longest stretch of 79.4 miles on I 20, offering a consistent pace. The profile is clearly highway-focused, meaning you'll experience relatively high speeds and fewer traffic lights for extended periods. While the main roads are primarily interstates like I 20 and I 26, the final leg utilizes US 501 Business, which may introduce a slight change in pace as you approach your destination.
This is a straightforward highway drive that stays mostly on I 20 and I 26. You will hit about 13 points where you need to pay attention to lane position or signs. The trickiest moment comes around 17.9 miles in near I 385 / Golden Strip Freeway.
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 245.8 miles you will encounter 13 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 17.9 miles (I 385 / Golden Strip Freeway): Merge point - match speed before joining. Lane positioning matters here; at 40.8 miles (I 26): Merge point - match speed before joining. Lane positioning matters here; at 95.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here.
Weekend Trip
Doable as a same-day drive at 5h 1m. Total distance: 245.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 1m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (89%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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