This 370.7-mile drive from Vancleave, Mississippi to Horn Lake, Mississippi is a substantial undertaking, estimated to take about 7 hours and 10 minutes of pure driving time. Primarily utilizing I-55 and US 49, this route is almost entirely highway, making it a straightforward journey across Mississippi. With a fuel cost estimated around $57, it's an economical trip for a single day, though you might appreciate splitting it with an overnight stay given the duration. The drive offers a consistent highway-focused experience, efficiently connecting these two points within the Southeast region.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
185.4 miles from Vancleave, MS
A natural place for your longest stop of the day
, about 3h 46m into the drive
.
Main Roads
Road
Distance
Duration
I 55
193.7 mi
3h 29m
US 49
135 mi
2h 46m
Biloxi-D'Iberville Scenic Expressway
20.4 mi
23m
I 10
10.1 mi
10m
MS 57
7.2 mi
10m
Goodman Road West
2.1 mi
3m
Hurt Road
0.5 mi
2m
Camelot Road
<0.1 mi
<1m
Longest stretch:
I 55
— 193.7 mi, about 3h 29m
Turn-by-Turn Driving Directions
Step-by-step road directions between Vancleave, MS and Horn Lake, MS.
1
Start on MS 57
7.2 mi·10 min·MS 57
2
Take the ramp
0.2 mi·32 sec
3
Merge onto I 10
10 mi·10 min·I 10
4
Take the exit
0.2 mi·20 sec
Exit 46D-BToward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
5
Keep slight left at fork
0.2 mi·23 sec
6
Keep slight right at fork
0.4 mi·46 sec
Exit 46CToward MS 15, MS 67: MS 15, MS 67
7
Merge onto MS 15; MS 67
20 mi·23 min·Biloxi-D'Iberville Scenic Expressway
Use the straight lane.
8
Keep slight right at fork
0.4 mi·47 sec
Toward US 49 North: Hattiesburg, Jackson
9
Merge onto US 49
40 mi·46 min·US 49
Use the straight lane.
10
Continue on US 49
2.4 mi·2 min·US 49
Use the straight / slight right lanes.
11
Turn straight onto US 49
10 mi·16 min·US 49
Use the straight lane.
12
Continue on US 49; MS 42
5.4 mi·6 min·US 49; MS 42
Use the straight lane.
13
Continue on US 49
5.3 mi·6 min·US 49
Use the straight lane.
14
Continue on US 49
0.2 mi·14 sec·US 49
Use the straight lane.
15
Continue on US 49
4.2 mi·4 min·US 49
Use the straight lane.
16
Continue on US 49
66 mi·1 hr 20 min·US 49
Use the straight lane.
17
Take the exit onto US 49
0.2 mi·21 sec·US 49
18
Keep slight left at fork onto US 49
0.7 mi·1 min·US 49
Toward Jackson
19
Keep slight right at fork onto US 49
0.9 mi·1 min·US 49
20
Merge onto I 55
194 mi·3 hr 29 min·I 55
21
Take the exit
0.3 mi·38 sec
Toward Southaven, Horn Lake, Olive Branch
22
Keep slight left at fork
192 ft·6 sec
Toward Memphis
23
Turn left onto MS 302
2.1 mi·3 min·Goodman Road West
24
Turn left onto Hurt Road
0.5 mi·2 min·Hurt Road
25
Turn right onto Camelot Road
193 ft·8 sec·Camelot Road
26
Arrive at destination
Camelot Road
Trip Plan
Given the 7 hour and 10 minute duration, starting your journey from Vancleave early in the morning will allow you to reach Horn Lake before evening. With only 2 recommended stops, plan them strategically to break up the 193.7-mile stretch on I-55. Keep an eye on your fuel gauge, as the estimated cost is $57 for the 370.7 miles. While doable in one day, consider an overnight stop if you prefer a more relaxed pace. A practical tip for this route is to ensure your vehicle is in good condition before departing, especially for the long stretches on the interstate.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 185.4 miles from Vancleave, MS, or about 3h 46m into the drive.
The longest continuous stretch on this route runs about 193.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 82 miles or 1h 38m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 185.4 miles or 3h 46m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 6h 2m
Traffic, exits, and arrival timing usually matter more near Horn Lake, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Vancleave, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
Day 1
Settle into the route from Vancleave, MS
This is one driving day of about 370.7 miles and 7h 10m.
Your first comfortable stop window is around 82 miles from Vancleave, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on I 55 for about 193.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 17.5 and 368.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
17.5 mi into trip|~21m in
Take the exit toward I 110, MS 15, MS 67: Biloxi, Keesler Air Force Base
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 46D-B
Toward I 110, MS 15, MS 67: Biloxi, Keesler Air...
5
17.7 mi into trip|~21m in
Keep slight left at fork
Highway fork - watch signs carefully
7
17.9 mi into trip|~22m in
Keep slight right at fork toward MS 15, MS 67: MS 15, MS 67
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 46C
Toward MS 15, MS 67: MS 15, MS 67
6
38.7 mi into trip|~47m in
Keep slight right at fork toward US 49 North: Hattiesburg, Jackson
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward US 49 North: Hattiesburg, Jackson
6
368.1 mi into trip|~7h 4m in
Keep slight left at fork toward Memphis
Highway fork - watch signs carefully
Toward Memphis
Fuel & Cost
Regular Gas
$55.98 one way
$111.97 round trip
$3.84/gal25.4 MPG avg130 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$61.46
$122.91
premium
$4.56
$66.54
$133.07
diesel
$5.61
$81.85
$163.69
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$56
Meals
$25–$50
Total
$81–$106
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 129.7 kg one way.
Prices: EIA weekly data, 2026-04-13.
EV Charging Along Route
7 DC fast chargers
· Coverage: good
Tesla Supercharger
Southaven, Mississippi
Tesla
1 DCFC
Tesla Supercharger
Horn Lake, Mississippi
Tesla
1 DCFC
Pilot Flying J Charging Station
Winona, Mississippi
Other
1 DCFC
ChargePoint Charging Station
Southaven, Mississippi
ChargePoint
1 DCFC
ChargePoint Charging Station
Southaven, Mississippi
ChargePoint
1 DCFC
Nissan Charging Station
Southaven, Mississippi
Other
1 DCFC
Chevrolet Charging Station
Wiggins, Mississippi
Other
1 DCFC
Other: 3
Tesla: 2
ChargePoint: 2
Station data from NREL Alternative Fuel Stations database.
Driving Electric?
About $39 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
111.2
1
$38.92
$17.79
Efficient EV
92.7
1
$32.44
$14.83
EV Truck/SUV
148.3
1
$51.90
$23.72
Gas CO2
130 kg
EV CO2
43 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 17, 2026
Origin
Vancleave, MS
Evening
in Vancleave on Saturday
Local time
8:26 PM
CDT
Current temp
61°F
Unavailable
Live forecast
Destination
Horn Lake, MS
Evening
in Horn Lake on Saturday
Local time
8:26 PM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
16 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
7h 10m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Medgar and Myrlie Evers Home National Monument
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
28 mi from route
~71 min detour
Free
near mile 306.8
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a highway-dominant experience on this route, with 99% of your travel on major roads like I-55 and US 49. You'll encounter the Biloxi-D'Iberville Scenic Expressway early on, but the bulk of the journey is on high-speed interstates. The longest uninterrupted stretch covers 193.7 miles on I-55, so be prepared for extended periods of consistent driving. This profile means you'll likely experience a predictable and efficient pace for most of the 7 hours and 10 minutes it takes to complete the trip.
Most of the miles stay on highways, which makes pacing and fuel planning easier than turn-by-turn city driving.
There are about 26 navigation steps in the underlying route data, so the final approach matters more than the middle miles.
I 55 is the longest continuous segment at about 193.7 miles.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on I 55 and US 49. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 17.5 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 370.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 17.5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 17.7 miles: Highway fork - watch signs carefully; at 17.9 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
395 ft28 ft
Total Climb
523 ft
Total Descent
256 ft
Highest Point
395 ft
~132.4 mi in
Elevation Range
367 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Vancleave, MS to Horn Lake, MS, road signs begin pointing toward Jackson along the way.
Jackson
38.7 mi in|~47m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 7h 10m. Total distance: 370.7 miles.
Family Friendly
Moderate complexity with 2 natural rest stops along the way.
Solo Traveler
7h 10m drive, plan rest stops for pacing.
Frequently Asked Questions
The drive from Vancleave, MS to Horn Lake, MS covers 370.7 miles and takes about 7h 10m without stops. Add 15-30 minutes for a fuel or rest stop on longer drives.
The main roads are I 55, US 49, Biloxi-D'Iberville Scenic Expressway. Most of the drive stays on highways, so watch for ramps and exits.
This is a comfortable same-day trip.
The midpoint is about 185.4 miles from Vancleave, MS. Look for rest areas, gas stations, or food options near the halfway mark.
At current regular gas prices, expect to spend about $55.98 one way. This estimate uses 25.4 MPG — your actual cost will vary with your vehicle's fuel efficiency and current gas prices.
Start early — leave by 6-7 AM to arrive at a reasonable hour. This is a long drive — plan for a morning departure or consider splitting it into two days.
Plan about 2 meaningful breaks for fuel, food, or rest. Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
This is a demanding drive. With 16 significant decision points across 370.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
The main spots that need attention: at 17.5 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 17.7 miles: Highway fork - watch signs carefully; at 17.9 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
On the drive from Vancleave, MS to Horn Lake, MS, road signs begin pointing toward Jackson along the way.
