Origin
Uxbridge, MA
Late night in Uxbridge on Sunday
Local time
1:59 AM
EDT
Current temp
62°F
Unavailable
Live forecast
Trip from Uxbridge, MA to Lowell, MA
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
1h 8m
Distance
50.6 mi
81 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$8
one way
EV Charging
Unknown
Best Time to Leave
4 AM
1h 3m
★
6 AM
1h 9m
8 AM
1h 20m
10 AM
1h 13m
12 PM
1h 11m
3 PM
1h 13m
5 PM
1h 19m
8 PM
1h 5m
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Uxbridge, MA
Wikimedia Commons
Lowell, MA
Phil Evenden
Trip Overview
Uxbridge to Lowell is 50.6 miles and takes about 1 hour 8 minutes via I-495, with a fuel budget near $8 and enough daylight to finish in a day. This drive primarily stays within Massachusetts, connecting two communities in the Northeast region. It's a fairly direct route, mostly on the interstate, making it a convenient option for a quick trip. Consider this if you need to get between these two points efficiently without much fuss. The overall journey is straightforward and doesn't involve significant detours or complex navigation.
Main Roads
| Road | Distance | Duration |
|---|---|---|
| I 495 | 37.5 mi | 43m |
| Mendon Street | 3.5 mi | 7m |
| Chelmsford Street | 2.6 mi | 4m |
| Uxbridge Road | 2.1 mi | 3m |
| Main Street | 1.6 mi | 2m |
| Cedar Street | 1.4 mi | 2m |
| Milford Street | 1 mi | 1m |
| Hastings Street | 0.3 mi | <1m |
Longest stretch:
I 495
— 37.5 mi, about 43m
Turn-by-Turn Driving Directions
Step-by-step road directions between Uxbridge, MA and Lowell, MA.
1
Start on this road
287 ft
·
24 sec
·
this road
2
At end of road, turn left onto MA 16
2.3 mi
·
5 min
·
Mendon Street
3
Continue on MA 16
2.1 mi
·
3 min
·
Uxbridge Road
4
Continue on MA 16
0.3 mi
·
28 sec
·
Hastings Street
5
Continue on MA 16
1.0 mi
·
1 min
·
Milford Street
6
Continue on MA 16
1.1 mi
·
2 min
·
Mendon Street
7
Continue on MA 16
1.6 mi
·
2 min
·
Main Street
8
Turn left onto MA 85
1.4 mi
·
2 min
·
Cedar Street
Use the left lane.
9
Take the ramp
0.2 mi
·
25 sec
Toward I 495 North: Lowell
10
Merge onto I 495
38 mi
·
43 min
·
I 495
Use the straight / slight right lanes.
11
Take the exit
0.2 mi
·
34 sec
Exit 88
Toward MA 110: Chelmsford, Lowell
12
Turn right onto MA 110
2.6 mi
·
4 min
·
Chelmsford Street
13
Turn right onto Cambridge Street
314 ft
·
14 sec
·
Cambridge Street
14
Turn left onto Hale Street
486 ft
·
13 sec
·
Hale Street
15
Arrive at destination
Hale Street
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
25 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
Pacing Suggestions
Fuel and coffee
A short stop after about 11 miles helps settle the day before fatigue starts building.
Meal break
The midpoint is around 25.3 miles from Uxbridge, MA, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 75 decision points cluster between mile 0.1 and 47.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0.1 mi into trip
|
~0m in
|
MA 16 / Mendon Street
At end of road, turn left onto MA 16 / Mendon Street
Navigation decision point
5
8.5 mi into trip
|
~16m in
|
MA 85 / Cedar Street
Turn left onto MA 85 / Cedar Street
Lane positioning matters here
Use the left lane.
4
9.9 mi into trip
|
~19m in
Take the ramp toward I 495 North: Lowell
Navigation decision point
Toward I 495 North: Lowell
5
10.1 mi into trip
|
~19m in
|
I 495
Merge onto I 495
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
6
47.6 mi into trip
|
~1h 2m in
Take the exit toward MA 110: Chelmsford, Lowell
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 88
Toward MA 110: Chelmsford, Lowell
Fuel & Cost
Regular Gas
$8.10 one way
$16.20 round trip
$4.07/gal
25.4 MPG avg
18 kg CO2
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.43 | $8.83 | $17.66 |
| premium | $4.82 | $9.61 | $19.22 |
| diesel | $5.61 | $11.17 | $22.34 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$8
Estimated CO2 emission: 17.7 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $5 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 15.2 | 0 | $5.31 | $2.43 |
| Efficient EV | 12.7 | 0 | $4.43 | $2.02 |
| EV Truck/SUV | 20.2 | 0 | $7.08 | $3.24 |
Gas CO2
18 kg
EV CO2
6 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Destination
Lowell, MA
Late night in Lowell on Sunday
Local time
1:59 AM
EDT
Current temp
63°F
Unavailable
Live forecast
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
1h 8m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
What kind of drive is this?
This is a highway-focused drive, with 74% of the route utilizing major highways. You'll spend a good portion of your time on I-495, which makes up the longest stretch of uninterrupted driving at 37.5 miles. Expect a consistent pace for much of the journey, allowing for steady progress. While Mendon Street and Chelmsford Street are part of the main roads, the character leans heavily towards the interstate experience. It's a drive designed for getting from point A to point B with relative speed.
74% highway — fuel and pacing are the main things to plan.
15 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 37.5 mi on I 495.
How Hard Is This Drive?
2/10
This is a straightforward highway drive that stays mostly on I 495 and Mendon Street. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes around 0.1 miles in near MA 16 / Mendon Street.
Driving Effort
2/10
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Uxbridge, MA to Lowell, MA is easy. At 1h 8m with 74% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (MA 16 / Mendon Street): Navigation decision point; at 8.5 miles (MA 85 / Cedar Street): Lane positioning matters here; at 9.9 miles: Navigation decision point.
About the Cities
Arriving in Lowell, MA
Full guide →Lowell is a city in Massachusetts about 40 minutes northwest of Boston. With over 115,000 residents (2020), it's the fifth largest city in Massachusetts, and has an important historical background. It was the first planned industrial city in the United States.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 1h 8m. Total distance: 50.6 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 8m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (74%). Straightforward navigation.
Frequently Asked Questions
The longest stretch is about 37.5 miles on I 495. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 0.1 miles (MA 16 / Mendon Street): Navigation decision point; at 8.5 miles (MA 85 / Cedar Street): Lane positioning matters here; at 9.9 miles: Navigation decision point.
Yes — Lowell National Historical Park, Minute Man National Historical Park and Blackstone River Valley National Historical Park (6 total within detour distance). See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Lowell, MA before heading back.
How this page is built
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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