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Trip from Uxbridge, MA to Cambridge, MA

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

1h 10m

Distance

45.8 mi

74 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$7

one way

EV Charging

Unknown

Best Time to Leave

Save up to 17 min
4 AM
1h 5m ★
6 AM
1h 10m
8 AM
1h 22m
10 AM
1h 14m
12 PM
1h 13m
3 PM
1h 15m
5 PM
1h 21m
8 PM
1h 7m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

town in Worcester County, Massachusetts, United States

Uxbridge, MA

Wikimedia Commons

city in Middlesex County, Massachusetts, United States of America

Cambridge, MA

Wikimedia Commons

Trip Overview

Uxbridge to Cambridge is 45.8 miles and takes about 1 hour 10 minutes via Massachusetts Turnpike, with a fuel budget near $7 and enough daylight to finish in a day. This trip stays within Massachusetts, connecting two points in the Northeast region. It's a straightforward, highway-focused drive that's ideal for a single-day excursion. You'll spend most of your time on major roadways, making it a practical choice when you need to get from point A to point B efficiently.

Main Roads

Road Distance Duration
Massachusetts Turnpike 19.1 mi 23m
I 495 8.6 mi 9m
Turnpike Road 3.6 mi 5m
Mendon Street 3.5 mi 7m
Uxbridge Road 2.1 mi 3m
Main Street 1.6 mi 2m
Cedar Street 1.4 mi 2m
Milford Street 1 mi 1m
Longest stretch: Massachusetts Turnpike — 19.1 mi, about 23m

Turn-by-Turn Driving Directions

Step-by-step road directions between Uxbridge, MA and Cambridge, MA.

1

Start on this road

287 ft · 24 sec · this road
2

At end of road, turn left onto MA 16

2.3 mi · 5 min · Mendon Street
3

Continue on MA 16

2.1 mi · 3 min · Uxbridge Road
4

Continue on MA 16

0.3 mi · 28 sec · Hastings Street
5

Continue on MA 16

1.0 mi · 1 min · Milford Street
6

Continue on MA 16

1.1 mi · 2 min · Mendon Street
7

Continue on MA 16

1.6 mi · 2 min · Main Street
8

Turn left onto MA 85

1.4 mi · 2 min · Cedar Street
Use the left lane.
9

Take the ramp

0.2 mi · 25 sec
Toward I 495 North: Lowell
10

Merge onto I 495

8.6 mi · 9 min · I 495
Use the straight / slight right lanes.
11

Take the exit

0.4 mi · 56 sec
Exit 59A Toward MA 9 East: Framingham Use the slight right lane.
12

Merge onto MA 9

3.6 mi · 5 min · Turnpike Road
Use the straight lane.
13

Continue on MA 9

0.8 mi · 1 min · Worcester Road
14

Take the exit

0.4 mi · 45 sec
Toward I 90 East, I 90 West: Masspike, Springfield, Boston
15

Keep slight right at fork

0.3 mi · 39 sec
Toward I 90 East: Boston, Massachusetts Turnpike East Use the slight right lane.
16

Merge onto I 90

19 mi · 23 min · Massachusetts Turnpike
Use the straight lane.
17

Take the exit

0.5 mi · 1 min
Exit 131 Toward Allston-Brighton, Cambridge, Fenway Park Use the slight left lane.
18

Keep slight right at fork

0.2 mi · 23 sec
Toward Cambridge, Somerville, Fenway Park Use the slight left / slight right lanes.
19

Turn slight right onto Cambridge Street

180 ft · 6 sec · Cambridge Street
20

Continue on River Street

0.8 mi · 2 min · River Street
Use the straight / left lanes.
21

Continue on Prospect Street

0.6 mi · 1 min · Prospect Street
22

Turn left onto Hampshire Street

0.1 mi · 33 sec · Hampshire Street
Use the left lane.
23

Continue on Cambridge Street

0.1 mi · 30 sec · Cambridge Street
Use the straight lane.
24

Turn right onto Line Street

0.2 mi · 51 sec · Line Street
25

Turn left onto Leonard Avenue

460 ft · 19 sec · Leonard Avenue
26

Arrive at destination

Leonard Avenue

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

city in Middlesex County, Massachusetts, United States

Mid-route town

Meal stop

Marlborough, MA

23 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Popular next leg

Marlborough, MA to Cambridge, MA

28.6 mi · 44m

Pacing Suggestions

Hopedale, MA

Fuel and coffee

A short stop after about 10 miles helps settle the day before fatigue starts building.

Cordaville, MA

Meal break

The midpoint is around 22.9 miles from Uxbridge, MA, which is a good place for a longer meal and fuel stop.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 15

5 decision points cluster between mile 8.5 and 43.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
8.5 mi into trip | ~16m in | MA 85 / Cedar Street

Turn left onto MA 85 / Cedar Street

Lane positioning matters here

Use the left lane.
7
18.8 mi into trip | ~29m in

Take the exit toward MA 9 East: Framingham

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the slight right lane. Exit 59A Toward MA 9 East: Framingham
8
23.9 mi into trip | ~37m in

Keep slight right at fork toward I 90 East: Boston, Massachusetts Turnpike East

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight right lane. Toward I 90 East: Boston, Massachusetts Turnpik...
8
43.3 mi into trip | ~1h 2m in

Take the exit toward Allston-Brighton, Cambridge, Fenway Park

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Exit 131 Toward Allston-Brighton, Cambridge, Fenway Park
8
43.8 mi into trip | ~1h 3m in

Keep slight right at fork toward Cambridge, Somerville, Fenway Park

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left / slight right lanes. Toward Cambridge, Somerville, Fenway Park

Fuel & Cost

Regular Gas

$7.33 one way

$14.66 round trip

$4.07/gal 25.4 MPG avg 16 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.43 $7.99 $15.99
premium $4.82 $8.70 $17.39
diesel $5.61 $10.11 $20.22

Estimated Tolls: $1.40

Massachusetts Turnpike (19.1 mi) $1.15
Turnpike Road (3.6 mi) $0.25

Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.

Drive Cost (one way)

Fuel

$7

Tolls

$1

Total

$9

Estimated CO2 emission: 16 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $5 in charging · 0 stops · 69% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 13.7 0 $4.81 $2.20
Efficient EV 11.5 0 $4.01 $1.83
EV Truck/SUV 18.3 0 $6.41 $2.93

Gas CO2

16 kg

EV CO2

5 kg (69% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 16, 2026

Origin

Uxbridge, MA

Late night in Uxbridge on Sunday

Local time

2:00 AM

EDT

Current temp

62°F

Unavailable

Live forecast

Destination

Cambridge, MA

Late night in Cambridge on Sunday

Local time

2:00 AM

EDT

Current temp

62°F

Unavailable

Live forecast

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

Very similar conditions

Both ends of the route are sitting at about the same temperature right now.

Road read

1h 10m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

This route is predominantly a highway-focused drive, with 68% of the journey on major arteries. Expect to spend a good portion of your time on the Massachusetts Turnpike, including an uninterrupted stretch of 19.1 miles. While the profile suggests a highway-centric experience, you'll transition between different sections of the Turnpike Road and I-495. The road character will likely feel consistent, emphasizing efficient travel over scenic detours.

68% highway — fuel and pacing are the main things to plan.
26 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 19.1 mi on Massachusetts Turnpike.

How Hard Is This Drive?

10/10

This is a straightforward highway drive that stays mostly on Massachusetts Turnpike and I 495. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 8.5 miles in near MA 85 / Cedar Street.

Driving Effort 10/10

Demanding - stay alert through the decision-heavy sections

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 45.8 miles you will encounter 15 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 8.5 miles (MA 85 / Cedar Street): Lane positioning matters here; at 18.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 23.9 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Uxbridge, MA and Cambridge, MA, road signs point toward Springfield, Boston, Massachusetts Turnpike East, Allston-Brighton and Fenway Park.

Springfield

23.5 mi in | ~37m

Boston

23.5 mi in | ~37m

Massachusetts Turnpike East

23.9 mi in | ~37m

Allston-Brighton

43.3 mi in | ~1h 2m

Fenway Park

43.3 mi in | ~1h 2m

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 1h 10m. Total distance: 45.8 miles.

Family Friendly

Moderate complexity with 0 natural rest stops along the way.

Solo Traveler

1h 10m drive, comfortable solo distance.

EV Driver

0 DC fast chargers along the route. Coverage: unknown.

First-Time Driver

Mostly highway driving (68%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 19.1 miles on Massachusetts Turnpike. The full list of main roads is in the Roads section above.

Expect about $1.40 in tolls one way, starting with Massachusetts Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Cambridge, MA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.

The main spots that need attention: at 8.5 miles (MA 85 / Cedar Street): Lane positioning matters here; at 18.8 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 23.9 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Yes — Boston National Historical Park, Minute Man National Historical Park and Adams National Historical Park (6 total within detour distance). See the National Parks section for detour distances and tips on detours.

Yes. A round trip is manageable in a single day if you plan a break at Cambridge, MA before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.

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