Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
1h 19m
Distance
63.4 mi
102 km
Drive Score
7/10
Good drive
Same Day?
Yes, doable
Fuel Cost
$10
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Sainte Genevieve, MO
Jermaine Lewis
St. Louis, MO to Sainte Genevieve, MO is 63.4 miles and takes about 1h 19m via I 55, with a fuel budget near $10 and enough daylight to finish in a day. This is a straightforward, highway-focused drive primarily within Missouri, taking you from the Midwest's urban edge into its more rural landscapes. You'll spend most of your time on major interstates and highways, making this a quick and efficient trip. Given its short duration, it's ideal for a same-day excursion, allowing you to maximize your time at your destination.
| Road | Distance | Duration |
|---|---|---|
| I 55 | 52.5 mi | 58m |
| US 61 | 7.3 mi | 10m |
| South Tucker Boulevard | 1.3 mi | 3m |
| Market Street | 1.2 mi | 3m |
| Gravois Avenue | 0.3 mi | <1m |
| MO O | 0.3 mi | <1m |
| South Main Street | 0.2 mi | <1m |
| Jefferson Street | <0.1 mi | <1m |
Step-by-step road directions between St. Louis, MO and Sainte Genevieve, MO.
Start on Market Street
Turn left onto South Tucker Boulevard
Turn straight onto Gravois Avenue
Take the ramp
Merge onto I 55
Take the exit
Turn left onto MO O
Turn right onto US 61
Turn left onto Market Street
Turn left onto South Main Street
Turn right onto Jefferson Street
Arrive at destination
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
32 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 14 miles helps settle the day before fatigue starts building.
The midpoint is around 31.7 miles from St. Louis, MO, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 1.7 and 63.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the ramp toward I 55 South: Memphis
Lane positioning matters here
Merge onto I 55
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward MO O
Exit ramp - move to the correct lane early
Turn left onto MO O
Navigation decision point
Turn right onto Jefferson Street
Navigation decision point
Regular Gas
$9.91 one way
$19.82 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.36 | $10.88 | $21.77 |
| premium | $4.89 | $12.20 | $24.40 |
| diesel | $5.61 | $14.00 | $28.00 |
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$10
Estimated CO2 emission: 22.2 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $7 in charging · 0 stops · 68% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 19 | 0 | $6.66 | $3.04 |
| Efficient EV | 15.9 | 0 | $5.55 | $2.54 |
| EV Truck/SUV | 25.4 | 0 | $8.88 | $4.06 |
Gas CO2
22 kg
EV CO2
7 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in St. Louis on Sunday
Local time
11:14 AM
CDT
Current temp
58°F
Chance Rain Showers then Partly Sunny
Destination
Morning in Sainte Genevieve on Sunday
Local time
11:14 AM
CDT
Current temp
56°F
Unavailable
57°F
Imperial, MO
32 mi in
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
This route is predominantly a highway drive, with 94% of it utilizing major roadways like I 55 and US 61. Expect a fast-paced journey for the most part, particularly during the longest stretch of 52.5 miles on I 55. The initial part of the drive might involve navigating through St. Louis on roads like South Tucker Boulevard before merging onto the interstate. The character remains consistently highway-oriented, prioritizing speed and directness over winding scenic byways, making for a predictable driving experience.
This is a straightforward highway drive that stays mostly on I 55 and US 61. There are only a few real navigation decisions along the way. The trickiest moment comes around 1.7 miles in.
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 19m drive. You will face about 9 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 1.7 miles: Lane positioning matters here; at 1.8 miles (I 55): Merge point - match speed before joining. Lane positioning matters here; at 54.2 miles: Exit ramp - move to the correct lane early.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from St. Louis, MO to Sainte Genevieve, MO, road signs begin pointing toward Mo O along the way.
Mo O
The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic Mississippi and Missouri rivers. And capping it all is the world's tallest man-made monument, the beautiful and iconic Gateway Arch. St. Louis is a city of culture and surprisingly inexpensive. Among American cities, only Washington, D.C. has more free attractions for tourists and residents alike. Hotels, restaurants, and even parking garages avoid the premium pricing common in other big cities. Although often overlooked, St. Louis can be an affordable, educational, and fun family getaway.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 1h 19m. Total distance: 63.4 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 19m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
First-Time Driver
Mostly highway driving (94%). Straightforward navigation.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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