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Trip from St. Louis, MO to Ashland, MO

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

2h 43m

Distance

135.4 mi

218 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$21

one way

EV Charging

Unknown

Best Time to Leave

Save up to 32 min
4 AM
2h 33m ★
6 AM
2h 43m
8 AM
3h 5m
10 AM
2h 51m
12 PM
2h 49m
3 PM
2h 52m
5 PM
3h 4m
8 PM
2h 37m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Ashland, MO, MO

Ashland, MO

Valeria Boltneva

Trip Overview

This 135.4-mile journey from St. Louis to Ashland, Missouri, will take approximately 2 hours and 43 minutes of driving time. Primarily utilizing the Dwight D. Eisenhower Highway, Avenue of the Saints, and US 63, this route is best suited as a single-day trip. With a fuel cost estimated at $21, it's an economical option for exploring the Midwest. The drive offers a blend of highway and local road experiences, making it a manageable and straightforward excursion for a day trip.

Trip Pace

Same-day drive is realistic

A same-day return is realistic if you keep stops short.

Break Rhythm

1 planned break

A short stop every 2 to 3 hours is enough for this drive.

Midpoint

67.7 miles from St. Louis, MO

A natural place for your longest stop of the day , about 1h 23m into the drive .

Main Roads

Road Distance Duration
Dwight D Eisenhower Highway 80.7 mi 1h 35m
Avenue of the Saints 27.8 mi 33m
US 63 13.1 mi 14m
Daniel Boone Expressway 5.7 mi 7m
Jack Buck Memorial Highway 4.3 mi 5m
Market Street 1.6 mi 3m
US 40 0.6 mi 1m
East Broadway 0.3 mi <1m
Longest stretch: Dwight D Eisenhower Highway — 80.7 mi, about 1h 35m

Turn-by-Turn Driving Directions

Step-by-step road directions between St. Louis, MO and Ashland, MO.

1

Start on Market Street

1.6 mi · 3 min · Market Street
2

Take the ramp

0.3 mi · 23 sec
Toward I 64 West, US 40 West: Wentzville
3

Merge onto I 64; US 40

4.3 mi · 5 min · Jack Buck Memorial Highway
Use the straight lane.
4

Continue on I 64; US 40

5.7 mi · 7 min · Daniel Boone Expressway
Use the straight lane.
5

Continue on I 64; US 40; US 61

28 mi · 33 min · Avenue of the Saints
Use the straight lane.
6

Take the exit onto US 40

0.6 mi · 1 min · US 40
Exit 1A Toward I 70 West, US 40 West: Kansas City Use the straight / slight left lanes.
7

Merge onto I 70; US 40

81 mi · 1 hr 35 min · Dwight D Eisenhower Highway
8

Take the exit

0.2 mi · 32 sec
Exit 128A Toward US 63: Jefferson City, Moberly
9

Turn left onto US 63 Conn

0.2 mi · 24 sec · US 63 Conn
Use the straight lane.
10

Take the exit

0.4 mi · 49 sec
Toward US 63 South: Jefferson City Use the straight lane.
11

Merge onto US 63

13 mi · 14 min · US 63
12

Take the exit

0.2 mi · 30 sec
13

Enter roundabout onto East Broadway

46 ft · 1 sec · East Broadway
14

Continue on East Broadway

0.2 mi · 29 sec · East Broadway
15

Enter roundabout onto MO Y

264 ft · 6 sec · East Broadway
16

Continue on MO Y

33 ft · 0 sec · East Broadway
17

Arrive at destination

MO Y

Trip Plan

For this 135.4-mile trip, leaving St. Louis in the morning will allow you ample time to reach Ashland without feeling rushed. Since it's a single-day drive with a projected duration of under 3 hours, you have flexibility with stops; consider planning one stop to break up the 80.7-mile longest stretch on the Dwight D. Eisenhower Highway. Keep an eye on your fuel, as the estimated cost is $21, and be prepared for the 'turn-heavy local drive' profile, which may require more active navigation. Enjoy the straightforward drive through Missouri.

Morning Departure

Leave by 9 AM and you'll arrive before lunch.

Evening Departure

Even a 4 PM departure gets you there before dark in summer.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 67.7 miles from St. Louis, MO, or about 1h 23m into the drive.
The longest continuous stretch on this route runs about 80.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 30 miles or 38m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 67.7 miles or 1h 23m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 2h 14m

Traffic, exits, and arrival timing usually matter more near Ashland, MO than in the middle of the route.

Before You Leave

+

Open the route before leaving St. Louis, MO so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from St. Louis, MO

This is one driving day of about 135.4 miles and 2h 43m.

Your first comfortable stop window is around 30 miles from St. Louis, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Dwight D Eisenhower Highway for about 80.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Dardenne Prairie, MO, MO

Mid-route town

Meal stop

Dardenne Prairie, MO

68 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Weldon Spring, MO

Fuel and coffee

A short stop after about 30 miles helps settle the day before fatigue starts building.

Warrenton, MO

Meal break

The midpoint is around 67.7 miles from St. Louis, MO, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Dwight D Eisenhower Highway if your tank is already low. That segment runs about 80.7 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 11

5 decision points cluster between mile 1.9 and 121.4 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
1.9 mi into trip | ~3m in | I 64; US 40 / Jack Buck Memorial Highway

Merge onto I 64; US 40 / Jack Buck Memorial Highway

Merge point - match speed before joining. Lane positioning matters here

Use the straight lane.
8
39.7 mi into trip | ~50m in | US 40

Take the exit onto US 40 toward I 70 West, US 40 West: Kansas City

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight left lanes. Exit 1A Toward I 70 West, US 40 West: Kansas City
6
121 mi into trip | ~2h 26m in

Take the exit toward US 63: Jefferson City, Moberly

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 128A Toward US 63: Jefferson City, Moberly
6
121.2 mi into trip | ~2h 26m in | US 63 Conn

Turn left onto US 63 Conn

Lane positioning matters here

Use the straight lane.
6
121.4 mi into trip | ~2h 27m in

Take the exit toward US 63 South: Jefferson City

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight lane. Toward US 63 South: Jefferson City

Fuel & Cost

Regular Gas

$21.17 one way

$42.34 round trip

$3.97/gal 25.4 MPG avg 47 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.36 $23.24 $46.48
premium $4.89 $26.06 $52.11
diesel $5.61 $29.89 $59.79

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$21

Meals

$25–$50

Total

$46–$71

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 47.4 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $14 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 40.6 0 $14.22 $6.50
Efficient EV 33.9 0 $11.85 $5.42
EV Truck/SUV 54.2 0 $18.96 $8.67

Gas CO2

47 kg

EV CO2

16 kg (66% less)

This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

St. Louis, MO

Night in St. Louis on Saturday

Local time

11:16 PM

CDT

Current temp

74°F

Unavailable

Live forecast

Destination

Ashland, MO

Night in Ashland on Saturday

Local time

11:16 PM

CDT

Current temp

73°F

Unavailable

Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

1 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

2h 43m on the road

Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a 'turn-heavy local drive' with only 14% of the route on highways. While you'll experience an 80.7-mile stretch on the Dwight D. Eisenhower Highway, the overall character is more about navigating through local roads. This means you'll encounter more frequent turns and potentially slower speeds compared to a pure interstate drive. The road's personality shifts between faster highway sections and more intricate local routes, requiring your attention throughout the 2-hour and 43-minute journey.

Only 14% highway — the rest is turn-by-turn surface driving.
17 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 80.7 mi on Dwight D Eisenhower Highway.

How Hard Is This Drive?

6/10

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 1.9 miles in near I 64; US 40 / Jack Buck Memorial Highway.

Driving Effort 6/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 135.4 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 1.9 miles (I 64; US 40 / Jack Buck Memorial Highway): Merge point - match speed before joining. Lane positioning matters here; at 39.7 miles (US 40): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 121 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from St. Louis, MO to Ashland, MO, road signs begin pointing toward Moberly along the way.

Moberly

121 mi in | ~2h 26m

About the Cities

Starting in St. Louis, MO

Full guide →

The Gateway City of St. Louis is the epitome of the modern Midwestern metropolis. Missouri's second-largest city is vibrant but laid-back, populous but navigable, historic but still relevant. The city's planners have created an aesthetically beautiful city, with plenty of green space amidst buildings both old and new, framed by the majestic Mississippi and Missouri rivers. And capping it all is the world's tallest man-made monument, the beautiful and iconic Gateway Arch. St. Louis is a city of culture and surprisingly inexpensive. Among American cities, only Washington, D.C. has more free attractions for tourists and residents alike. Hotels, restaurants, and even parking garages avoid the premium pricing common in other big cities. Although often overlooked, St. Louis can be an affordable, educational, and fun family getaway.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 2h 43m. Total distance: 135.4 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

2h 43m drive, comfortable solo distance.

Scenic Drive

Mostly surface roads route profile.

Frequently Asked Questions

The longest stretch is about 80.7 miles on Dwight D Eisenhower Highway. The full list of main roads is in the Roads section above.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Ashland, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 1.9 miles (I 64; US 40 / Jack Buck Memorial Highway): Merge point - match speed before joining. Lane positioning matters here; at 39.7 miles (US 40): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 121 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one.

Yes. A round trip is manageable in a single day if you plan a break at Ashland, MO before heading back.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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Explore More

Return Trip

Ashland, MO to St. Louis, MO

Plan the drive back the other way.

135.5 mi 2h 42m

Explore more options from St. Louis, MO or browse trips ending in Ashland, MO.

Looking for more statewide routes? Browse MO road trips.