Simonton Lake to Jeffersonville is 273.2 miles and takes about 5h 32m via I 65, with a fuel budget near $43 and enough daylight to finish in a day. This drive stays within Indiana, moving from the Midwest region to another part of the Midwest. It's a straightforward trip primarily on major highways, making it a good option for a single-day journey. You'll find it's a practical route for reaching your destination without too many detours.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
136.6 miles from Simonton Lake, IN
A natural place for your longest stop of the day
, about 2h 52m into the drive
.
Main Roads
Road
Distance
Duration
I 65
100.8 mi
1h 48m
US 31
94.2 mi
1h 57m
South Michigan Street
24.9 mi
29m
I 69
13.6 mi
15m
Saint Joseph Valley Parkway
12.9 mi
14m
Keystone Parkway
5.2 mi
7m
North Nappanee Street
4.5 mi
6m
I 465
4 mi
4m
Longest stretch:
I 65
— 100.8 mi, about 1h 48m
Turn-by-Turn Driving Directions
Step-by-step road directions between Simonton Lake, IN and Jeffersonville, IN.
1
Start on SR 19
3.6 mi·5 min·Cassopolis Street
2
Turn right onto SR 19
1.7 mi·2 min·East Bristol Street
3
Continue on SR 19
4.5 mi·6 min·North Nappanee Street
4
Take the ramp
0.5 mi·1 min
5
Merge onto US 20
13 mi·14 min·Saint Joseph Valley Parkway
6
Take the exit
0.3 mi·32 sec
Toward US 31 South: Plymouth, Indianapolis
7
Merge onto BUS US 31
25 mi·29 min·South Michigan Street
8
Merge onto US 31
0.9 mi·1 min·US 31
9
Turn slight right
512 ft·6 sec
10
Continue on US 31
85 mi·1 hr 44 min·US 31
11
Turn right onto East 226th Street
270 ft·10 sec·East 226th Street
12
Turn left
320 ft·50 sec
13
Continue on this road
320 ft·25 sec·this road
14
Turn right onto East 226th Street
270 ft·9 sec·East 226th Street
15
Turn right onto US 31
8.0 mi·10 min·US 31
16
Take the exit
0.2 mi·28 sec
Exit 129BToward Keystone Parkway, Rangeline Road, Clay Terrace BoulevardUse the slight right lane.
17
Keep slight left at fork onto Keystone Parkway
5.2 mi·7 min·Keystone Parkway
Toward Keystone ParkwayUse the straight / slight right lanes.
18
Enter roundabout
137 ft·7 sec
Toward I 465: South Keystone Avenue
19
Continue
0.3 mi·32 sec
Toward I 465: South Keystone Avenue
20
Keep slight left at fork
430 ft·10 sec
Toward I 465 East: Keystone Avenue South
21
Keep slight right at fork
0.8 mi·2 min
Toward I 465 EastUse the slight left / right lanes.
22
Merge onto I 465
4.0 mi·4 min·I 465
23
Merge onto I 69; I 465
11 mi·12 min·I 69; I 465
Use the straight / slight right lanes.
24
Continue on I 69; I 74; I 465
2.3 mi·2 min·I 69; I 74; I 465
25
Take the exit
0.2 mi·31 sec
Exit 52Toward Emerson AvenueUse the straight / slight right lanes.
26
Keep slight left at fork
0.2 mi·28 sec
Use the slight left / slight right lanes.
27
Turn straight onto South Emerson Avenue
2.6 mi·4 min·South Emerson Avenue
Use the straight lane.
28
Turn right onto East Southport Road
0.5 mi·52 sec·East Southport Road
29
Take the ramp
0.3 mi·43 sec
30
Merge onto I 65
101 mi·1 hr 48 min·I 65
31
Take the exit
0.3 mi·32 sec
Exit 1Toward US 31 South: Jeffersonville, Clarksville
32
Turn straight onto US 31
0.7 mi·1 min·US 31
33
Turn slight right
0.5 mi·1 min
34
Continue on East 10th Street
419 ft·12 sec·East 10th Street
35
Turn right onto Wall Street
0.2 mi·38 sec·Wall Street
36
Turn left onto East 8th Street
0.2 mi·32 sec·East 8th Street
37
Turn right onto Watt Street
0.2 mi·34 sec·Watt Street
38
Arrive at destination
Watt Street
Trip Plan
Given the 5h 32m estimated duration, starting your drive in the morning is advisable to allow for a comfortable pace. With only one recommended stop and a longest stretch of over 100 miles, plan your breaks strategically, perhaps around the halfway point or when you feel the need to stretch. Keep an eye on your fuel gauge, especially during the 100.8-mile stretch on I 65, and be aware that the $43 fuel cost is an estimate, so actual prices may vary. Making sure you have enough gas before entering longer highway segments will prevent any unnecessary delays.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 136.6 miles from Simonton Lake, IN, or about 2h 52m into the drive.
The longest continuous stretch on this route runs about 100.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 60 miles or 1h 15m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 136.6 miles or 2h 52m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 36m
Traffic, exits, and arrival timing usually matter more near Jeffersonville, IN than in the middle of the route.
Before You Leave
+
Open the route before leaving Simonton Lake, IN so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Simonton Lake, IN
This is one driving day of about 273.2 miles and 5h 32m.
Your first comfortable stop window is around 60 miles from Simonton Lake, IN.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 65 for about 100.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 27
5 decision points cluster between mile 142.1 and 166.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
8
142.1 mi into trip|~2h 59m in
Take the exit toward Keystone Parkway, Rangeline Road, Clay Terrace Boulevard
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 129B
Toward Keystone Parkway, Rangeline Road, Clay T...
7
142.3 mi into trip|~3h in|Keystone Parkway
Keep slight left at fork onto Keystone Parkway toward Keystone Parkway
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward Keystone Parkway
7
147.9 mi into trip|~3h 9m in
Keep slight right at fork toward I 465 East
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left / right lanes.
Toward I 465 East
7
166.4 mi into trip|~3h 31m in
Take the exit toward Emerson Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the straight / slight right lanes.
Exit 52
Toward Emerson Avenue
7
166.6 mi into trip|~3h 32m in
Keep slight left at fork
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left / slight right lanes.
Fuel & Cost
Regular Gas
$42.71 one way
$85.42 round trip
$3.97/gal25.4 MPG avg96 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.36
$46.90
$93.79
premium
$4.89
$52.57
$105.15
diesel
$5.61
$60.32
$120.64
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$43
Meals
$25–$50
Total
$68–$93
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 95.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $29 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
82
1
$28.69
$13.11
Efficient EV
68.3
0
$23.90
$10.93
EV Truck/SUV
109.3
1
$38.25
$17.48
Gas CO2
96 kg
EV CO2
32 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 16, 2026
Origin
Simonton Lake, IN
Night
in Simonton Lake on Saturday
Local time
9:14 PM
EDT
Current temp
67°F
Unavailable
Live forecast
Destination
Jeffersonville, IN
Night
in Jeffersonville on Saturday
Local time
9:14 PM
EDT
Current temp
76°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
9 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 32m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This route is predominantly a highway-focused drive, with 84% of it on interstates and major roads. Expect to spend the majority of your time on I 65 and US 31. The longest uninterrupted stretch you'll encounter is 100.8 miles on I 65, so be prepared for extended periods of consistent speed. While the profile is highway-centric, the inclusion of South Michigan Street in the main roads suggests there might be some brief transitions to local roads, but the overall feel is one of efficient travel.
84% highway — fuel and pacing are the main things to plan.
38 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 100.8 mi on I 65.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on I 65 and US 31. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 142.1 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 27 significant decision points across 273.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 142.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 142.3 miles (Keystone Parkway): Highway fork - watch signs carefully. Lane positioning matters here; at 147.9 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Simonton Lake, IN to Jeffersonville, IN, road signs begin pointing toward Indianapolis along the way.
Indianapolis
23.2 mi in|~31m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 5h 32m. Total distance: 273.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 32m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (84%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 100.8 miles on I 65. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Jeffersonville, IN before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 142.1 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 142.3 miles (Keystone Parkway): Highway fork - watch signs carefully. Lane positioning matters here; at 147.9 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Not recommended in a single day. At 5.5 hours each way, a round trip means 11.1 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Jeffersonville, IN before the return drive.
