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Trip from Satsuma, AL to Florence, AL

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

6h 41m

Distance

358.2 mi

576 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$54

one way

EV Charging

Unknown

Best Time to Leave

Save up to 36 min
4 AM
6h 30m ★
6 AM
6h 42m
8 AM
7h 6m
10 AM
6h 50m
12 PM
6h 48m
3 PM
6h 51m
5 PM
7h 5m
8 PM
6h 35m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Satsuma, AL, AL

Satsuma, AL

Engin Akyurt

city and county seat of Lauderdale County, Alabama, United States

Florence, AL

Wikimedia Commons

Trip Overview

Traveling from Satsuma to Florence covers 358.2 miles across Alabama, taking approximately 6 hours and 41 minutes of pure drive time. Since this route remains entirely within the Southeast, you will experience consistent regional surroundings as you head north. It is a straightforward trip that fits comfortably into a single day, though it certainly demands focus behind the wheel. You should budget about $55 for fuel to complete the journey. Given the duration, a single planned stop is sufficient to keep you refreshed without adding significant time to your arrival in Florence.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

179.1 miles from Satsuma, AL

A natural place for your longest stop of the day , about 3h 15m into the drive .

Main Roads

Road Distance Duration
I 65 290 mi 5h 15m
University of North Alabama Highway 55.4 mi 1h 6m
Woodward Avenue 4.2 mi 7m
Wheeler Highway 4.2 mi 5m
US 43 3.6 mi 6m
South Pine Street 0.2 mi <1m
West Doctor Hicks Boulevard <0.1 mi <1m
Section Line Road <0.1 mi <1m
Longest stretch: I 65 — 290 mi, about 5h 15m

Turn-by-Turn Driving Directions

Step-by-step road directions between Satsuma, AL and Florence, AL.

1

Start on Railroad Street

140 ft · 12 sec · Railroad Street
2

Turn right onto US 43

1.8 mi · 2 min · US 43
3

Take the ramp

0.2 mi · 22 sec
4

Merge onto I 65

290 mi · 5 hr 15 min · I 65
Use the straight / slight right lanes.
5

Take the exit

0.2 mi · 29 sec
Exit 310 Toward AL 157: Cullman, Moulton
6

Turn left onto AL 157

200 ft · 3 sec · Section Line Road
7

Continue on AL 157

55 mi · 1 hr 6 min · University of North Alabama Highway
Use the straight lane.
8

Merge onto US 72 Alternate; AL 20; AL 157

4.2 mi · 5 min · Wheeler Highway
Use the straight lane.
9

Turn right onto US 43; US 72; AL 13; AL 17

4.2 mi · 7 min · Woodward Avenue
Use the straight lane.
10

Take the exit onto US 43; US 72; AL 13; AL 17; AL 20

1.8 mi · 3 min · US 43; US 72; AL 13; AL 17; AL 20
Use the slight right lane.
11

Turn left onto West Doctor Hicks Boulevard

437 ft · 15 sec · West Doctor Hicks Boulevard
Use the left lane.
12

Turn right onto South Pine Street

0.2 mi · 34 sec · South Pine Street
13

Arrive at destination

North Pine Street

Trip Plan

To maximize your efficiency, aim for an early morning departure to clear the bulk of the 358.2-mile distance before peak traffic hours. Since the longest stretch spans 290 miles on I-65, ensure your vehicle is fueled up before hitting the interstate to avoid unnecessary detours. Plan your one recommended stop strategically around the halfway mark to break up the monotony of the long highway segments. Keep in mind that while the route is manageable in one day, staying alert during the final transition onto Woodward Avenue is essential for a smooth arrival. Being prepared for the shift from high-speed interstate driving to local highway navigation will help you finish your trip safely.

Morning Departure

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Evening Departure

This is a long drive — plan for a morning departure or consider splitting it into two days.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 179.1 miles from Satsuma, AL, or about 3h 15m into the drive.
The longest continuous stretch on this route runs about 290 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 79 miles or 1h 26m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 179.1 miles or 3h 15m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 5h 26m

Traffic, exits, and arrival timing usually matter more near Florence, AL than in the middle of the route.

Before You Leave

+

Open the route before leaving Satsuma, AL so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Satsuma, AL

This is one driving day of about 358.2 miles and 6h 41m.

Your first comfortable stop window is around 79 miles from Satsuma, AL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 65 for about 290 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Mid-route town

Meal stop

Hoover, AL

179 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Andalusia, AL

Fuel and coffee

A short stop after about 79 miles helps settle the day before fatigue starts building.

Thorsby, AL

Meal break

The midpoint is around 179.1 miles from Satsuma, AL, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 65 if your tank is already low. That segment runs about 290 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 10

5 decision points cluster between mile 2 and 357.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
2 mi into trip | ~3m in | I 65

Merge onto I 65

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
6
292 mi into trip | ~5h 18m in

Take the exit toward AL 157: Cullman, Moulton

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 310 Toward AL 157: Cullman, Moulton
5
347.6 mi into trip | ~6h 25m in | US 72 Alternate; AL 20; AL 157 / Wheeler Highway

Merge onto US 72 Alternate; AL 20; AL 157 / Wheeler Highway

Merge point - match speed before joining. Lane positioning matters here

Use the straight lane.
5
351.8 mi into trip | ~6h 30m in | US 43; US 72; AL 13; AL 17 / Woodward Avenue

Turn right onto US 43; US 72; AL 13; AL 17 / Woodward Avenue

Lane positioning matters here

Use the straight lane.
6
357.9 mi into trip | ~6h 41m in | West Doctor Hicks Boulevard

Turn left onto West Doctor Hicks Boulevard

Lane positioning matters here

Use the left lane.

Fuel & Cost

Regular Gas

$54.10 one way

$108.19 round trip

$3.84/gal 25.4 MPG avg 125 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.21 $59.39 $118.77
premium $4.56 $64.29 $128.59
diesel $5.61 $79.09 $158.17

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$54

Meals

$25–$50

Total

$79–$104

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 125.3 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $38 in charging · 1 stop · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 107.5 1 $37.61 $17.19
Efficient EV 89.6 1 $31.34 $14.33
EV Truck/SUV 143.3 1 $50.15 $22.92

Gas CO2

125 kg

EV CO2

42 kg (66% less)

Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 15, 2026

Origin

Satsuma, AL

Evening in Satsuma on Saturday

Local time

8:27 PM

CDT

Current temp

81°F

Unavailable

Live forecast

Destination

Florence, AL

Evening in Florence on Saturday

Local time

8:27 PM

CDT

Current temp

77°F

Unavailable

Live forecast

76°F

Hoover, AL

179 mi in

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

4 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

6h 41m on the road

Start early — leave by 6-7 AM to arrive at a reasonable hour.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

Birmingham Civil Rights National Monument

Birmingham Civil Rights National Monument

National Monument

In 1963, images of snarling police dogs unleashed against non-violent protesters and of children being sprayed with high-pressure hoses appeared in print and television news around the world. These dr...

4 mi from route ~11 min detour Free near mile 247
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

Expect a highway-focused experience, as 82% of your drive takes place on major roads. The journey is defined by a significant 290-mile stretch on I-65, which serves as the backbone of your trip. Once you exit the interstate, the character of the road shifts as you transition onto the University of North Alabama Highway and Woodward Avenue. While the interstate portion offers a steady, fast-paced rhythm, the final leg requires more attention as you navigate toward your destination. You will spend the vast majority of your time maintaining consistent highway speeds before the route winds down on local thoroughfares.

82% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 290 mi on I 65.

How Hard Is This Drive?

5/10

This is a straightforward highway drive that stays mostly on I 65 and University of North Alabama Highway. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes around 2 miles in near I 65.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 358.2 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 2 miles (I 65): Merge point - match speed before joining. Lane positioning matters here; at 292 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 347.6 miles (US 72 Alternate; AL 20; AL 157 / Wheeler Highway): Merge point - match speed before joining. Lane positioning matters here.

Elevation Profile

Mostly flat terrain

712 ft 20 ft

Total Climb

957 ft

Total Descent

427 ft

Highest Point

712 ft

~332.6 mi in

Elevation Range

691 ft

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

On the drive from Satsuma, AL to Florence, AL, road signs begin pointing toward Moulton along the way.

Moulton

292 mi in | ~5h 18m

About the Cities

Arriving in Florence, AL

Full guide →

Florence is a city in northwest Alabama near Mississippi and Tennessee.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 6h 41m. Total distance: 358.2 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

6h 41m drive, plan rest stops for pacing.

First-Time Driver

Mostly highway driving (82%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 290 miles on I 65. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This is a long drive, so arriving tired and in the dark compounds. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Florence, AL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 2 miles (I 65): Merge point - match speed before joining. Lane positioning matters here; at 292 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 347.6 miles (US 72 Alternate; AL 20; AL 157 / Wheeler Highway): Merge point - match speed before joining. Lane positioning matters here.

Yes — Birmingham Civil Rights National Monument. See the National Parks section for detour distances and tips on detours.

Not recommended in a single day. At 6.7 hours each way, a round trip means 13.4 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Florence, AL before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and NPS for national parks. See our methodology for refresh cadence and limitations.

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