Traveling from Satsuma to Florence covers 358.2 miles across Alabama, taking approximately 6 hours and 41 minutes of pure drive time. Since this route remains entirely within the Southeast, you will experience consistent regional surroundings as you head north. It is a straightforward trip that fits comfortably into a single day, though it certainly demands focus behind the wheel. You should budget about $55 for fuel to complete the journey. Given the duration, a single planned stop is sufficient to keep you refreshed without adding significant time to your arrival in Florence.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
179.1 miles from Satsuma, AL
A natural place for your longest stop of the day
, about 3h 15m into the drive
.
Main Roads
Road
Distance
Duration
I 65
290 mi
5h 15m
University of North Alabama Highway
55.4 mi
1h 6m
Woodward Avenue
4.2 mi
7m
Wheeler Highway
4.2 mi
5m
US 43
3.6 mi
6m
South Pine Street
0.2 mi
<1m
West Doctor Hicks Boulevard
<0.1 mi
<1m
Section Line Road
<0.1 mi
<1m
Longest stretch:
I 65
— 290 mi, about 5h 15m
Traffic on I-65
Hour-of-day weekday pattern from 55 FHWA count stations on your route.
Peak
3 PM
~825 veh/hr typical
· worst 1,223
Quietest
1 AM
~118 veh/hr
Peak-to-quiet ratio
7×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Satsuma, AL and Florence, AL.
1
Start on Railroad Street
140 ft·12 sec·Railroad Street
2
Turn right onto US 43
1.8 mi·2 min·US 43
3
Take the ramp
0.2 mi·22 sec
4
Merge onto I 65
290 mi·5 hr 15 min·I 65
Use the straight / slight right lanes.
5
Take the exit
0.2 mi·29 sec
Exit 310Toward AL 157: Cullman, Moulton
6
Turn left onto AL 157
200 ft·3 sec·Section Line Road
7
Continue on AL 157
55 mi·1 hr 6 min·University of North Alabama Highway
Use the straight lane.
8
Merge onto US 72 Alternate; AL 20; AL 157
4.2 mi·5 min·Wheeler Highway
Use the straight lane.
9
Turn right onto US 43; US 72; AL 13; AL 17
4.2 mi·7 min·Woodward Avenue
Use the straight lane.
10
Take the exit onto US 43; US 72; AL 13; AL 17; AL 20
1.8 mi·3 min·US 43; US 72; AL 13; AL 17; AL 20
Use the slight right lane.
11
Turn left onto West Doctor Hicks Boulevard
437 ft·15 sec·West Doctor Hicks Boulevard
Use the left lane.
12
Turn right onto South Pine Street
0.2 mi·34 sec·South Pine Street
13
Arrive at destination
North Pine Street
Trip Plan
To maximize your efficiency, aim for an early morning departure to clear the bulk of the 358.2-mile distance before peak traffic hours. Since the longest stretch spans 290 miles on I-65, ensure your vehicle is fueled up before hitting the interstate to avoid unnecessary detours. Plan your one recommended stop strategically around the halfway mark to break up the monotony of the long highway segments. Keep in mind that while the route is manageable in one day, staying alert during the final transition onto Woodward Avenue is essential for a smooth arrival. Being prepared for the shift from high-speed interstate driving to local highway navigation will help you finish your trip safely.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 179.1 miles from Satsuma, AL, or about 3h 15m into the drive.
The longest continuous stretch on this route runs about 290 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 79 miles or 1h 26m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 179.1 miles or 3h 15m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 26m
Traffic, exits, and arrival timing usually matter more near Florence, AL than in the middle of the route.
Before You Leave
+
Open the route before leaving Satsuma, AL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Satsuma, AL
This is one driving day of about 358.2 miles and 6h 41m.
Your first comfortable stop window is around 79 miles from Satsuma, AL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 65 for about 290 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 2 and 357.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
2 mi into trip|~3m in|I 65
Merge onto I 65
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
6
292 mi into trip|~5h 18m in
Take the exit toward AL 157: Cullman, Moulton
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 310
Toward AL 157: Cullman, Moulton
5
347.6 mi into trip|~6h 25m in|US 72 Alternate; AL 20; AL 157 / Wheeler Highway
Merge onto US 72 Alternate; AL 20; AL 157 / Wheeler Highway
Merge point - match speed before joining. Lane positioning matters here
Use the straight lane.
5
351.8 mi into trip|~6h 30m in|US 43; US 72; AL 13; AL 17 / Woodward Avenue
Turn right onto US 43; US 72; AL 13; AL 17 / Woodward Avenue
Lane positioning matters here
Use the straight lane.
6
357.9 mi into trip|~6h 41m in|West Doctor Hicks Boulevard
Turn left onto West Doctor Hicks Boulevard
Lane positioning matters here
Use the left lane.
Fuel & Cost
Regular Gas
$49.72 one way
$99.45 round trip
$3.53/gal25.4 MPG avg125 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$3.95
$55.63
$111.27
premium
$4.29
$60.49
$120.97
diesel
$4.80
$67.63
$135.27
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$50
Meals
$25–$50
Total
$75–$100
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 125.3 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $38 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
107.5
1
$37.61
$17.19
Efficient EV
89.6
1
$31.34
$14.33
EV Truck/SUV
143.3
1
$50.15
$22.92
Gas CO2
125 kg
EV CO2
42 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 17, 2026
Origin
Satsuma, AL
Evening
in Satsuma on Saturday
Local time
8:30 PM
CDT
Current temp
76°F
Partly Cloudy
W 5 mph1% chanceLive forecast
Destination
Florence, AL
Evening
in Florence on Saturday
Local time
8:30 PM
CDT
Current temp
73°F
Patchy Fog
0 mph5% chanceLive forecast
94°F
Helena, AL
179 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
3 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 41m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Birmingham Civil Rights National Monument
National Monument
In 1963, images of snarling police dogs unleashed against non-violent protesters and of children being sprayed with high-pressure hoses appeared in print and television news around the world. These dr...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a highway-focused experience, as 82% of your drive takes place on major roads. The journey is defined by a significant 290-mile stretch on I-65, which serves as the backbone of your trip. Once you exit the interstate, the character of the road shifts as you transition onto the University of North Alabama Highway and Woodward Avenue. While the interstate portion offers a steady, fast-paced rhythm, the final leg requires more attention as you navigate toward your destination. You will spend the vast majority of your time maintaining consistent highway speeds before the route winds down on local thoroughfares.
82% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 290 mi on I 65.
How Hard Is This Drive?
5/10
This is a straightforward highway drive that stays mostly on I 65 and University of North Alabama Highway. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes around 2 miles in near I 65.
Driving Effort5/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 358.2 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 2 miles (I 65): Merge point - match speed before joining. Lane positioning matters here; at 292 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 347.6 miles (US 72 Alternate; AL 20; AL 157 / Wheeler Highway): Merge point - match speed before joining. Lane positioning matters here.
Elevation Profile
Mostly flat terrain
712 ft20 ft
Total Climb
957 ft
Total Descent
427 ft
Highest Point
712 ft
~332.6 mi in
Elevation Range
691 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Satsuma, AL to Florence, AL, road signs begin pointing toward Moulton along the way.
Doable as a same-day drive at 6h 41m. Total distance: 358.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 41m drive, plan rest stops for pacing.
First-Time Driver
Mostly highway driving (82%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 290 miles on I 65. The full list of main roads is in the Roads section above.
Yes — we found about 26 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This is a long drive, so arriving tired and in the dark compounds. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Florence, AL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 26 rest areas along the route for bathroom stops.
The main spots that need attention: at 2 miles (I 65): Merge point - match speed before joining. Lane positioning matters here; at 292 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 347.6 miles (US 72 Alternate; AL 20; AL 157 / Wheeler Highway): Merge point - match speed before joining. Lane positioning matters here.
Yes — Birmingham Civil Rights National Monument. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 6.7 hours each way, a round trip means 13.4 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Florence, AL before the return drive.
