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Trip from Santa Rosa, TX to San Antonio, TX

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Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Jul 20, 2026 · Editorial standards

Drive Time

4h 41m

Distance

248 mi

399 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$34

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
4h 28m ★
6 AM
4h 41m
8 AM
5h 8m
10 AM
4h 51m
12 PM
4h 48m
3 PM
4h 52m
5 PM
5h 7m
8 PM
4h 33m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Santa Rosa, TX, TX

Santa Rosa, TX

Mark Direen

Downtown San Antonio, TX, TX

San Antonio, TX

Wikimedia Commons

Trip Overview

Santa Rosa, TX to San Antonio, TX is 248 miles and takes about 4h 41m via I 69C and US 281, with a fuel budget near $37 and enough daylight to finish in a day. This trip takes you across the vast Great Plains region of Texas, staying within the state for the entire duration. It's a straightforward drive, mostly on highways, making it a convenient option for a single-day trip. You'll find the route efficient for covering ground between these two points. Consider this an easy transit between two points in the same region.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

124 miles from Santa Rosa, TX

A natural place for your longest stop of the day , about 2h 23m into the drive .

Main Roads

Road Distance Duration
I 69C 141.7 mi 2h 35m
US 281 69 mi 1h 11m
Nueces Street 14.7 mi 18m
East Santa Rosa Avenue 9.1 mi 13m
Santa Cruz Avenue 8.4 mi 12m
East Richardson Road 1.2 mi 1m
Richardson Road 0.9 mi 1m
East Commerce Street 0.9 mi 1m
Longest stretch: I 69C — 141.7 mi, about 2h 35m

Turn-by-Turn Driving Directions

Step-by-step road directions between Santa Rosa, TX and San Antonio, TX.

1

Start on FM 506

44 ft · 6 sec · Santa Rosa Boulevard
2

Turn right onto TX 107

8.4 mi · 12 min · Santa Cruz Avenue
3

Continue on TX 107

9.1 mi · 13 min · East Santa Rosa Avenue
4

Turn right onto FM 2128

0.9 mi · 1 min · Richardson Road
5

Continue on FM 2128

0.5 mi · 40 sec · East Schunior Street
6

Continue on FM 2128

0.8 mi · 1 min · East Richardson Street
7

Continue on FM 2128

1.2 mi · 1 min · East Richardson Road
8

Turn right onto North Expressway 281

181 ft · 3 sec · North Expressway 281
9

Take the ramp

0.3 mi · 35 sec
Toward I 69C North, US 281 North
10

Merge onto I 69C; US 281

71 mi · 1 hr 15 min · I 69C; US 281
Use the straight / slight right lanes.
11

Keep slight right at fork onto I 69C; US 281

70 mi · 1 hr 19 min · I 69C; US 281
12

Keep slight left at fork onto US 281

15 mi · 18 min · Nueces Street
13

Continue on US 281

0.2 mi · 15 sec · US 281
14

Take the exit onto US 281

69 mi · 1 hr 11 min · US 281
Use the straight / slight right lanes.
15

Take the exit

0.3 mi · 33 sec
Exit 141 Toward Commerce Street, Downtown, The Alamo Use the straight / slight right lanes.
16

Turn straight onto Interstate 37 South

380 ft · 11 sec · Interstate 37 South
17

Turn left onto East Commerce Street

0.9 mi · 1 min · East Commerce Street
18

Turn left onto Military Plaza

392 ft · 15 sec · Military Plaza
19

Turn left onto Dolorosa Street

327 ft · 8 sec · Dolorosa Street
20

Arrive at destination

Dolorosa Street

Trip Plan

Given the 4h 41m duration, departing Santa Rosa in the morning allows ample time to reach San Antonio well before evening. With only one recommended stop and a short driving time, you have flexibility in pacing. Keep an eye on your fuel gauge, as the estimated cost is $37, and services can be spread out on longer highway stretches like the 141.7 miles on I 69C. Plan your fuel stops accordingly to avoid any inconvenience. This is a manageable one-day drive, so you can decide on your stop timing as you go.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 124 miles from Santa Rosa, TX, or about 2h 23m into the drive.
The longest continuous stretch on this route runs about 141.7 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 55 miles or 1h 7m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 124 miles or 2h 23m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 3h 53m

Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.

Before You Leave

+

Open the route before leaving Santa Rosa, TX so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Santa Rosa, TX

This is one driving day of about 248 miles and 4h 41m.

Your first comfortable stop window is around 55 miles from Santa Rosa, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 69C for about 141.7 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Downtown Alice, TX, TX

Mid-route town

Meal stop

Alice, TX

124 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Doolittle, TX

Fuel and coffee

A short stop after about 55 miles helps settle the day before fatigue starts building.

Alice, TX

Meal break

The midpoint is around 124 miles from Santa Rosa, TX, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before I 69C if your tank is already low. That segment runs about 141.7 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Stops Along Your Drive

Picked by where they fit in your drive — first break, midpoint reset, final stretch.

Rest Area

0 mi from route

Brooks County Rest Area

0 mi from route

Picnic Area

0 mi from route

TA

0.1 mi from route

Love's Travel Stop

0.1 mi from route

Love's Travel Stop

0.1 mi from route

Rest Area

0.1 mi from route

Live Oak County Southbound Rest Area

0.1 mi from route

Picnic Area

0.1 mi from route

Flying J Travel Center

0.1 mi from route

Pilot Travel Center

0.1 mi from route

QuikTrip

0.1 mi from route

Pilot Travel Center

0.2 mi from route

Live Oak County Northbound Rest Area

0.3 mi from route

Spanish Governor's Palace

4.5 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.1 mi from route

San Antonio, Texas

Hours: 9 am–5 pm

+12102077527

Visit website

GO RIO San Antonio River Cruises

4.6 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.4 mi from route ~1 min detour

San Antonio, Texas

Hours: 10 am–10 pm

+12102274746

Visit website

San Antonio | The Saga

4.5 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0 mi from route

San Antonio, Texas

Hours: 9–9:30 pm

+12102259800

Visit website

Hemisfair

4.7 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.5 mi from route ~1 min detour

San Antonio, Texas

Hours: 5 am–12 pm

+12107094750

Visit website

San Antonio Fire Museum

4.9 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.6 mi from route ~1 min detour

San Antonio, Texas

Hours: 10 am–3:30 pm

+12103907236

Visit website

The Amazing Mirror Maze

4.4 ★ ★ ★ ★ ☆

Near the end, right off the route

Home stretch 0.4 mi from route ~1 min detour

San Antonio, Texas

Hours: 10:30 am–8 pm

+12102242288

Visit website

SEA LIFE San Antonio

4.1 ★ ★ ★ ★ ☆

Near the end, right off the route

Home stretch 0.4 mi from route ~1 min detour

San Antonio, Texas

Hours: 10 am–5 pm

+12106101160

Visit website

San Antonio River Lock & Dam

4.7 ★ ★ ★ ★ ★

Near the end, right off the route

Home stretch 0.8 mi from route ~2 min detour

San Antonio, Texas

Hours: 9 am–10 pm

+12102271373

Visit website

Place data sourced from public business listings. Hours and availability may vary.

Heads-up: tricky spots

5 of 11

5 decision points cluster between mile 21 and 247.9 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

5
21 mi into trip | ~31m in

Take the ramp toward I 69C North, US 281 North

Multiple destination signs - pick the right one

Toward I 69C North, US 281 North
5
21.2 mi into trip | ~32m in | I 69C; US 281

Merge onto I 69C; US 281

Merge point - match speed before joining. Lane positioning matters here

Use the straight / slight right lanes.
5
177.8 mi into trip | ~3h 26m in | US 281

Take the exit onto US 281

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes.
8
246.6 mi into trip | ~4h 38m in

Take the exit toward Commerce Street, Downtown, The Alamo

Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one

Use the straight / slight right lanes. Exit 141 Toward Commerce Street, Downtown, The Alamo
5
247.9 mi into trip | ~4h 41m in | Dolorosa Street

Turn left onto Dolorosa Street

Navigation decision point

Fuel & Cost

Regular Gas

$33.97 one way

$67.94 round trip

$3.48/gal 25.4 MPG avg 87 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $3.89 $37.94 $75.88
premium $4.23 $41.25 $82.50
diesel $4.80 $46.83 $93.65

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$34

Meals

$25–$50

Total

$59–$84

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 86.8 kg one way. Prices: EIA weekly data, 2026-07-13.

Driving Electric?

About $26 in charging · 0 stops · 67% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 74.4 0 $26.04 $11.90
Efficient EV 62 0 $21.70 $9.92
EV Truck/SUV 99.2 1 $34.72 $15.87

Gas CO2

87 kg

EV CO2

29 kg (67% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Jul 18, 2026

Origin

Santa Rosa, TX

Late night in Santa Rosa on Monday

Local time

1:23 AM

CDT

Current temp

98°F

Mostly Sunny

SSE 9 to 18 mph 0% chance Live forecast

Flood Warning

Flood Warning issued July 18 at 6:54AM CDT until July 21 at 4:06AM CDT by NWS Corpus Christi TX

Flood Warning

Flood Warning issued July 18 at 6:53AM CDT until July 20 at 4:50AM CDT by NWS Corpus Christi TX

Destination

San Antonio, TX

Late night in San Antonio on Monday

Local time

1:23 AM

CDT

Current temp

93°F

Partly Sunny

SSE 10 mph 2% chance Live forecast

Flood Warning

Flood Warning issued July 18 at 6:54AM CDT until July 21 at 4:06AM CDT by NWS Corpus Christi TX

Flood Warning

Flood Warning issued July 18 at 6:53AM CDT until July 20 at 4:50AM CDT by NWS Corpus Christi TX

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

5 degrees cooler at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

4h 41m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

National Parks Near This Route

Worth a detour if your schedule allows.

San Antonio Missions National Historical Park

San Antonio Missions National Historical Park

National Historical Park

Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...

2 mi from route ~4 min detour Free near mile 239.4
View on nps.gov
Palo Alto Battlefield National Historical Park

Palo Alto Battlefield National Historical Park

National Historical Park

On May 8, 1846, U.S. and Mexican troops clashed on the prairie of Palo Alto. The battle was the first in a two-year long war that changed the map of North America. Although the two countries have deve...

28 mi from route ~69 min detour Free
View on nps.gov

Park data from the National Park Service API. Alerts update every 2 hours.

What kind of drive is this?

This drive is predominantly highway, with 85% of the 248 miles on major roadways. You'll experience a longest stretch of 141.7 miles on I 69C, offering a sustained period of highway cruising. The transition to surface streets like Nueces Street will occur later in the trip, closer to San Antonio. Expect a consistent flow of traffic and numerous exits during the highway portions.

85% highway — fuel and pacing are the main things to plan.
20 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 141.7 mi on I 69C.

How Hard Is This Drive?

5/10

This is a straightforward highway drive that stays mostly on I 69C and US 281. You will hit about 11 points where you need to pay attention to lane position or signs. The trickiest moment comes around 21 miles in.

Driving Effort 5/10

Moderate - straightforward overall, but long enough or busy enough to require pacing

Balances navigation complexity with total wheel time.

This drive requires moderate attention. Across 248 miles you will encounter 11 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.

Where does it get tricky?

The main spots that need attention: at 21 miles: Multiple destination signs - pick the right one; at 21.2 miles (I 69C; US 281): Merge point - match speed before joining. Lane positioning matters here; at 177.8 miles (US 281): Exit ramp - move to the correct lane early. Lane positioning matters here.

Elevation Profile

Mostly flat terrain

649 ft 51 ft

Total Climb

809 ft

Total Descent

211 ft

Highest Point

649 ft

~248 mi in

Elevation Range

598 ft

About the Cities

Starting in Santa Rosa, TX

Full guide →

Arriving in San Antonio, TX

Full guide →

Founded 1718

San Antonio is the second largest city in the state of Texas and the 7th largest in the United States. It's the 24th largest metropolitan area in the country. Visited by more than 31 million annual visitors, San Antonio is a beautiful city at the axis of three different geological terrains: Hill Country, South Texas Plains and Prairie and Lakes. There's a lot to do in this city: fine art museums, historical missions and plenty of amusement parks in addition to great dining and lots of drinking. The culture and people are vibrant and interesting. San Antonio's downtown is one of the most lively in the nation.

Top landmarks

  • Alamo Mission in San Antonio — historic place in San Antonio, Bexar County, Texas
  • San Antonio Missions National Historical Park — historic district in San Antonio, Bexar County, Texas
  • Fort Sam Houston — military base in San Antonio, Texas

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 4h 41m. Total distance: 248 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

4h 41m drive, comfortable solo distance.

First-Time Driver

Mostly highway driving (85%). Some complex stretches to watch for.

Frequently Asked Questions

The longest stretch is about 141.7 miles on I 69C. The full list of main roads is in the Roads section above.

Yes — we found about 14 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.

Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.

The main spots that need attention: at 21 miles: Multiple destination signs - pick the right one; at 21.2 miles (I 69C; US 281): Merge point - match speed before joining. Lane positioning matters here; at 177.8 miles (US 281): Exit ramp - move to the correct lane early. Lane positioning matters here.

Yes — San Antonio Missions National Historical Park and Palo Alto Battlefield National Historical Park. See the National Parks section for detour distances and tips on detours.

Possible but tiring. At 4.7 hours each way, an in-and-out day trip would put you behind the wheel for 9.4 hours — manageable with a long break at San Antonio, TX, but most travelers stay overnight.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, USGS 3DEP for elevation, and NPS for national parks. See our methodology for refresh cadence and limitations.

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