The Serpent Center
Early in the drive, ~10 min detour
Vance, South Carolina
+18034921500
Visit websiteCompiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
1h 57m
Distance
95.5 mi
154 km
Drive Score
9/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$15
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Saint Matthews, SC
Wikimedia Commons
Florence, SC
Wikimedia Commons
If you are planning a trip from Saint Matthews to Florence, South Carolina, expect a journey covering 95.5 miles. You should set aside approximately 1 hour and 57 minutes of drive time to complete this trek. Because this is a relatively short distance, it functions perfectly as a simple day trip, requiring no overnight stays. Budget around $15 for fuel to cover the distance comfortably. Navigating through the Southeast, you will find this path is a practical way to connect these two South Carolina towns without the need for complex travel logistics.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
47.8 miles from Saint Matthews, SC
A natural place for your longest stop of the day , about 1h 1m into the drive .
| Road | Distance | Duration |
|---|---|---|
| I 95 | 63.6 mi | 1h 8m |
| Old State Road | 15.7 mi | 23m |
| Five Chop Road | 8.6 mi | 10m |
| West Evans Street | 2.4 mi | 4m |
| I 20 Bus | 1.6 mi | 2m |
| Harry C Raysor Drive | 1.2 mi | 2m |
| West Cheves Street | 0.7 mi | 1m |
| Saint Matthews Road | 0.6 mi | <1m |
Step-by-step road directions between Saint Matthews, SC and Florence, SC.
Start on this road
Turn left onto SC 6
Turn right onto US 601
Continue on US 601
Turn left onto US 176
Turn left onto US 301
Take the exit onto US 15; US 301
Merge onto I 95
Take the exit
Merge onto I 20 Bus
Turn left onto S-21-31
Turn right onto Warley Street
Turn left onto West Cheves Street
Turn right
Turn right
Arrive at destination
Given the local nature of these roads, flexibility is your greatest advantage when planning your departure. Because the drive clocks in under two hours, you can easily manage the trip in one go without needing scheduled rest stops. Keep a close eye on your fuel gauge before heading out, as the $15 cost estimate assumes consistent travel on local routes. Since you will be navigating turn-heavy segments, consider checking your navigation apps for traffic alerts on Bridge Street before you leave to ensure the smoothest possible transition between these two South Carolina locations.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 21 miles or 31m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 47.8 miles or 1h 1m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 34m
Traffic, exits, and arrival timing usually matter more near Florence, SC than in the middle of the route.
Open the route before leaving Saint Matthews, SC so your first major turns are already loaded.
Day 1
Settle into the route from Saint Matthews, SC
This is one driving day of about 95.5 miles and 1h 57m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
48 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 21 miles helps settle the day before fatigue starts building.
The midpoint is around 47.8 miles from Saint Matthews, SC, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before I 95 if your tank is already low. That segment runs about 63.6 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Picked by where they fit in your drive — first break, midpoint reset, final stretch.
Early in the drive, ~10 min detour
Vance, South Carolina
+18034921500
Visit websitePlace data sourced from public business listings. Hours and availability may vary.
5 decision points cluster between mile 0 and 95.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn left onto SC 6 / Bridge Street
Navigation decision point
Take the exit onto US 15; US 301
Exit ramp - move to the correct lane early. Lane positioning matters here
Merge onto I 95
Merge point - match speed before joining. Lane positioning matters here
Take the exit toward I 20 Business East: Florence
Exit ramp - move to the correct lane early
Turn right
Navigation decision point
Regular Gas
$14.93 one way
$29.87 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.34 | $16.33 | $32.66 |
| premium | $4.70 | $17.68 | $35.35 |
| diesel | $5.61 | $21.09 | $42.17 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$15
Meals
$25–$50
Total
$40–$65
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 33.4 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $10 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 28.7 | 0 | $10.03 | $4.58 |
| Efficient EV | 23.9 | 0 | $8.36 | $3.82 |
| EV Truck/SUV | 38.2 | 0 | $13.37 | $6.11 |
Gas CO2
33 kg
EV CO2
11 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Saint Matthews on Tuesday
Local time
4:12 AM
EDT
Current temp
84°F
Unavailable
Destination
Late night in Florence on Tuesday
Local time
4:12 AM
EDT
Current temp
85°F
Unavailable
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Expect a turn-heavy local drive rather than a monotonous interstate sprint, as this route features zero highway travel. You will primarily navigate via Bridge Street, Harry C. Raysor Drive, and Saint Matthews Road to reach your destination. Since the highway share is 0%, your focus will remain on local roads that demand more active attention from the driver. This profile offers a more personal, ground-level perspective of the regional landscape compared to a standard high-speed commute.
This is a straightforward highway drive that stays mostly on I 95 and Old State Road. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive near SC 6 / Bridge Street.
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 1h 57m drive. You will face about 12 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start (SC 6 / Bridge Street): Navigation decision point; at 26.2 miles (US 15; US 301): Exit ramp - move to the correct lane early. Lane positioning matters here; at 26.5 miles (I 95): Merge point - match speed before joining. Lane positioning matters here.
Florence is a city in the Pee Dee Country Region of South Carolina. It was the site of the Florence Stockade, a Confederate POW camp, notably bad but still maybe not as bad as Andersonville, then a railroad hub, and nowadays a regional center for medical care and manufacturing, including as it sits at the terminus for I-20. Even though it got started rather late, in 1871, it's more or less the hub for northeastern South Carolina, aka Pee Dee Country.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 1h 57m. Total distance: 95.5 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
1h 57m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (69%). Straightforward navigation.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
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