Origin
Saint Marys, PA
Late night in Saint Marys on Tuesday
Local time
4:54 AM
EDT
Current temp
43°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 21, 2026 · Editorial standards
Drive Time
4h 48m
Distance
233.7 mi
376 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$39
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Saint Marys, PA
RDNE Stock project
Bethlehem, PA
Wikimedia Commons
This 233.7-mile drive from Saint Marys to Bethlehem, Pennsylvania, is best tackled in a single day, taking approximately 4 hours and 48 minutes. You'll primarily navigate the Keystone Shortway and the William Penn Highway, with State Route 54 also playing a role. With a fuel cost estimated at $39 and a highway share of only 5%, this route offers a more local feel. Given its duration and the region you're traveling within (Northeast to Northeast), it's a manageable day trip, allowing for flexibility in your schedule. Expect a fairly turn-heavy local drive for much of the journey.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
116.9 miles from Saint Marys, PA
A natural place for your longest stop of the day , about 2h 20m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Keystone Shortway | 112.7 mi | 2h 1m |
| William Penn Highway | 21.6 mi | 26m |
| State Route 54 | 11.1 mi | 13m |
| Million Dollar Highway | 10.9 mi | 16m |
| Center Avenue | 10.6 mi | 12m |
| Lehigh Valley Thruway | 10.3 mi | 14m |
| Elysburg Road | 9.7 mi | 11m |
| Sunbury Road | 9.4 mi | 11m |
Step-by-step road directions between Saint Marys, PA and Bethlehem, PA.
Start on PA 120; PA 255
Turn left onto PA 120; PA 255
Turn slight left onto PA 120
Continue on PA 255
Continue on PA 255
Turn left onto PA 153
Turn left
Merge onto I 80
Take the exit
Turn slight left
Turn right onto PA 54
Continue on PA 54
Continue on PA 54
Turn left onto PA 54
Continue on PA 54
Continue on PA 901
Continue on PA 901
Continue on PA 901
Continue on PA 901
Turn right onto PA 901
Turn right onto PA 901
Continue on PA 901
Turn left onto PA 183
Turn right onto PA 61
Continue on PA 61
Continue on PA 61
Take the exit
Merge onto I 78; US 22
Keep slight right at fork onto US 22
Take the exit
Keep slight right at fork
Continue on PA 378
Take the exit
Turn right onto 8th Avenue
Turn left onto West Union Boulevard
Turn left onto Center Street
Turn right onto East Goepp Street
Turn right onto Linden Street
Arrive at destination
With a total duration of under 5 hours, this drive from Saint Marys to Bethlehem is well-suited for a single day. Plan to depart in the morning to allow ample time for the drive and any potential brief stops. The longest stretch of 112.7 miles on the Keystone Shortway means you can cover significant ground before needing to refuel. Given the route's turn-heavy local character, staying alert and mindful of speed limits will be key. With only one recommended stop and a reasonable fuel cost of $39, this trip offers a straightforward and budget-friendly travel experience.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 51 miles or 1h 10m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 116.9 miles or 2h 20m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 52m
Traffic, exits, and arrival timing usually matter more near Bethlehem, PA than in the middle of the route.
Open the route before leaving Saint Marys, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Marys, PA
This is one driving day of about 233.7 miles and 4h 48m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
117 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 51 miles helps settle the day before fatigue starts building.
The midpoint is around 116.9 miles from Saint Marys, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Keystone Shortway if your tank is already low. That segment runs about 112.7 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 140.2 and 232 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the exit toward PA 54: Danville, Washingtonville
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight right at fork onto US 22 / Lehigh Valley Thruway toward US 22 East: Pennsylvania Turnpike, LVI Airport
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward PA 378 South: Bethlehem, Schoenersville Road
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Keep slight right at fork toward PA 378 South: Bethlehem
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward Eighth Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Regular Gas
$38.74 one way
$77.49 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $42.43 | $84.87 |
| premium | $4.93 | $45.32 | $90.65 |
| diesel | $5.61 | $51.60 | $103.20 |
Estimated Tolls: $0.72
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$39
Tolls
$1
Meals
$25–$50
Total
$64–$89
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 81.8 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $25 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 70.1 | 0 | $24.54 | $11.22 |
| Efficient EV | 58.4 | 0 | $20.45 | $9.35 |
| EV Truck/SUV | 93.5 | 1 | $32.72 | $14.96 |
Gas CO2
82 kg
EV CO2
27 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Saint Marys on Tuesday
Local time
4:54 AM
EDT
Current temp
43°F
Unavailable
Destination
Late night in Bethlehem on Tuesday
Local time
4:54 AM
EDT
Current temp
61°F
Unavailable
63°F
Williamsport, PA
117 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Scenic Trail
The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...
Park data from the National Park Service API. Alerts update every 2 hours.
This route is characterized as a turn-heavy local drive, with only a 5% highway share, meaning you'll experience more varied road conditions than a typical interstate cruise. The longest uninterrupted stretch is 112.7 miles along the Keystone Shortway, offering a period of more consistent travel before you transition onto other roads. Be prepared for a dynamic driving experience that shifts between faster sections and more winding local roads as you progress toward Bethlehem. This isn't a monotonous highway journey; rather, it's a route that keeps you engaged with its changing scenery and road types.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 140.2 miles in.
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 21 significant decision points across 233.7 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 140.2 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 219.5 miles (US 22 / Lehigh Valley Thruway): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 229.7 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Saint Marys, PA and Bethlehem, PA, road signs point toward Washingtonville and Lvi Airport.
Washingtonville
Lvi Airport
Weekend Trip
Doable as a same-day drive at 4h 48m. Total distance: 233.7 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 48m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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