Saint Charles, MO to Ozark, MO is 228.2 miles and takes about 4h 20m via Henry Shaw Ozark Corridor, Schoolcraft Freeway, and I 270, with a fuel budget near $36 and enough daylight to finish in a day. This trip stays within the Midwest, specifically Missouri, for its entirety. Expect a drive that largely utilizes surface roads, making it a more relaxed pace compared to interstate-only routes. With a recommended one-day drive, you have flexibility for spontaneous stops or enjoying the scenery along the way. The relatively low fuel cost is also a practical consideration for budget-minded travelers.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
114.1 miles from Saint Charles, MO
A natural place for your longest stop of the day
, about 2h 12m into the drive
.
Main Roads
Road
Distance
Duration
Henry Shaw Ozark Corridor
189.8 mi
3h 25m
Schoolcraft Freeway
11 mi
13m
I 270
10.9 mi
13m
American Legion Memorial Highway
4.6 mi
5m
I 70
2.7 mi
3m
Dougherty Ferry Road
2.5 mi
4m
Jackson Street
1.4 mi
3m
South Fifth Street
1.1 mi
2m
Longest stretch:
Henry Shaw Ozark Corridor
— 189.8 mi, about 3h 25m
Traffic on I-44
Hour-of-day weekday pattern from 14 FHWA count stations on your route.
Peak
4 PM
~1,711 veh/hr typical
· worst 2,202
Quietest
2 AM
~187 veh/hr
Peak-to-quiet ratio
9.1×
busier at peak than in the quiet hours
12a6anoon6p11p
Averaged across 52 weeks of 2023 FHWA Travel Monitoring Analysis System data. Weekday hours only (Mon–Fri).
Turn-by-Turn Driving Directions
Step-by-step road directions between Saint Charles, MO and Ozark, MO.
1
Start on North Second Street
0.2 mi·38 sec·North Second Street
2
Turn right onto Jefferson Street
0.2 mi·44 sec·Jefferson Street
3
Turn left onto MO 94
1.1 mi·2 min·South Fifth Street
Use the straight / right lanes.
4
Take the ramp
0.2 mi·14 sec
Toward I 70 EastUse the left / straight lanes.
5
Merge onto I 70
2.7 mi·3 min·I 70
6
Take the exit
0.2 mi·12 sec
Exit 232Toward I 270: Chicago, MemphisUse the slight right lane.
7
Keep slight right at fork
0.4 mi·33 sec
Toward I 270 South: MemphisUse the slight right lane.
8
Continue on this road
0.1 mi·10 sec·this road
Exit 232Toward I 270 South: Memphis
9
Merge onto I 270
11 mi·13 min·I 270
Use the straight lane.
10
Take the exit
0.3 mi·28 sec
Exit 8Toward Dougherty Ferry RoadUse the slight right lane.
11
Turn right onto Dougherty Ferry Road
2.5 mi·4 min·Dougherty Ferry Road
Use the straight lane.
12
Continue on Forest Avenue
1.0 mi·2 min·Forest Avenue
13
Turn left onto MO 141
0.7 mi·1 min·MO 141
14
Take the exit
105 ft·3 sec
15
Turn right onto North Highway Drive
0.1 mi·14 sec·North Highway Drive
16
Take the ramp
0.2 mi·13 sec
Toward I 44 West, US 50 West: Rolla
17
Merge onto I 44; US 50
190 mi·3 hr 25 min·Henry Shaw Ozark Corridor
Use the straight lane.
18
Take the exit
0.3 mi·48 sec
Exit 82AToward US 65 South: Branson
19
Merge onto US 65
11 mi·13 min·Schoolcraft Freeway
Use the straight / slight right lanes.
20
Continue on US 65
4.6 mi·5 min·American Legion Memorial Highway
21
Take the exit onto US 65 Business
0.2 mi·33 sec·US 65 Business
Toward US 65 Busienss, MO 14: Nixa
22
Turn left onto US 65 Bus; MO 14
0.1 mi·24 sec·West Jackson Road
23
Continue on US 65 Bus; MO 14
1.4 mi·3 min·Jackson Street
24
Turn left onto West Church Street
97 ft·4 sec·West Church Street
25
Arrive at destination
West Church Street
Trip Plan
To make the most of this 4h 20m drive, consider leaving Saint Charles in the morning to allow ample time for the 228.2-mile trip to Ozark. Since it's a single-day drive, you won't need to worry about overnight accommodations, giving you flexibility. Keep an eye on your fuel gauge, especially as you pass the 189.8-mile mark on the Henry Shaw Ozark Corridor, as services might be more spread out on surface roads. The estimated fuel cost of $36 is a good baseline, but it's always wise to have a little extra. With only one stop recommended, plan it strategically for a meal or a break.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 114.1 miles from Saint Charles, MO, or about 2h 12m into the drive.
The longest continuous stretch on this route runs about 189.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 50 miles or 1h 3m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 114.1 miles or 2h 12m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 31m
Traffic, exits, and arrival timing usually matter more near Ozark, MO than in the middle of the route.
Before You Leave
+
Open the route before leaving Saint Charles, MO so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Saint Charles, MO
This is one driving day of about 228.2 miles and 4h 20m.
Your first comfortable stop window is around 50 miles from Saint Charles, MO.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Henry Shaw Ozark Corridor for about 189.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 18
5 decision points cluster between mile 0.2 and 16 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.2 mi into trip|~0m in|Jefferson Street
Turn right onto Jefferson Street
Navigation decision point
6
0.4 mi into trip|~1m in|MO 94 / South Fifth Street
Turn left onto MO 94 / South Fifth Street
Lane positioning matters here
Use the straight / right lanes.
8
4.3 mi into trip|~7m in
Take the exit toward I 270: Chicago, Memphis
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 232
Toward I 270: Chicago, Memphis
7
4.5 mi into trip|~8m in
Keep slight right at fork toward I 270 South: Memphis
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 270 South: Memphis
7
16 mi into trip|~22m in
Take the exit toward Dougherty Ferry Road
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the slight right lane.
Exit 8
Toward Dougherty Ferry Road
Fuel & Cost
Regular Gas
$33.70 one way
$67.40 round trip
$3.75/gal25.4 MPG avg80 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.14
$37.20
$74.41
premium
$4.72
$42.37
$84.74
diesel
$4.80
$43.09
$86.18
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$34
Meals
$25–$50
Total
$59–$84
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 79.8 kg one way.
Prices: EIA weekly data, 2026-07-13.
Driving Electric?
About $24 in charging
· 0 stops
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
68.5
0
$23.96
$10.95
Efficient EV
57.1
0
$19.97
$9.13
EV Truck/SUV
91.3
1
$31.95
$14.60
Gas CO2
80 kg
EV CO2
27 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jul 18, 2026
Origin
Saint Charles, MO
Late night
in Saint Charles on Sunday
Local time
5:42 AM
CDT
Current temp
95°F
Sunny
W 10 mph7% chanceLive forecast
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 18 at 8:00PM CDT by NWS Memphis TN
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 19 at 9:00PM CDT by NWS Memphis TN
Destination
Ozark, MO
Late night
in Ozark on Sunday
Local time
5:42 AM
CDT
Current temp
90°F
Slight Chance Showers And Thunderstorms
SW 10 mph19% chanceLive forecast
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 18 at 8:00PM CDT by NWS Memphis TN
Heat Advisory
Heat Advisory issued July 18 at 12:07PM CDT until July 19 at 9:00PM CDT by NWS Memphis TN
89°F
Cuba, MO
114 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
5 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 20m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Wilson's Creek National Battlefield
National Battlefield
Wilson's Creek was the first major Civil War battle fought west of the Mississippi River, and where the first Union general was killed in action. The costly Southern victory on August 10, 1861, focuse...
10 mi from route
~24 min detour
Free
near mile 220.4
Gateway Arch National Park commemorates President Jefferson’s vision of a continental nation, the individuals and cultural groups who helped shape its history, St. Louis’ role in westward expansion, a...
14 mi from route
~36 min detour
$19
near mile 15.7
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This 228.2-mile drive is mostly surface roads, with only about 11% on highways like I 270. You'll experience a long stretch of 189.8 miles on the Henry Shaw Ozark Corridor, which will feel like cruising through more populated areas with frequent intersections. The transition from highway to surface roads will be noticeable as you encounter more local traffic and varying speed limits. Expect to navigate through towns and suburban areas rather than open interstate miles.
Only 11% highway — the rest is turn-by-turn surface driving.
25 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 189.8 mi on Henry Shaw Ozark Corridor.
How Hard Is This Drive?
8/10
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.2 miles in near Jefferson Street.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 18 significant decision points across 228.2 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.2 miles (Jefferson Street): Navigation decision point; at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Gently rolling terrain
1,410 ft491 ft
Total Climb
1,164 ft
Total Descent
488 ft
Highest Point
1,410 ft
~211.9 mi in
Elevation Range
919 ft
Detours Along the Way
Tagged by where each one fits in your drive — first break, midpoint, final stretch.
St. Charles, Missouri is outside of St. Louis on the bank of the Missouri River. It was Missouri's first state capital and was one of the first stops by Lewis and Clark on their journey to explore Louisiana Territory. The historic Main Street has largely been restored to its 1812-era appearance including gas lights a boardwalk and is lined with shops selling artwork, handicrafts, home decorations, antiques. There are also many restaurants.
Top landmarks
•First Missouri State Capitol State Historic Site — historic site in Missouri, United States
•African Church — church building in Missouri, United States of America
•Frenchtown Historic District — historic district in St. Charles County, Missouri
Doable as a same-day drive at 4h 20m. Total distance: 228.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 20m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 189.8 miles on Henry Shaw Ozark Corridor. The full list of main roads is in the Roads section above.
Yes — we found about 19 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Ozark, MO before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 19 rest areas along the route for bathroom stops.
The main spots that need attention: at 0.2 miles (Jefferson Street): Navigation decision point; at 0.4 miles (MO 94 / South Fifth Street): Lane positioning matters here; at 4.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Wilson's Creek National Battlefield and Gateway Arch National Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.3 hours each way, an in-and-out day trip would put you behind the wheel for 8.7 hours — manageable with a long break at Ozark, MO, but most travelers stay overnight.
