Ruleville, MS to Southaven, MS is 105.5 miles and takes about 2h 19m via US 61, US 49, and Highway 49, with a fuel budget near $16 and enough daylight to finish in a day. This drive stays within Mississippi, taking you through the Southeast region. It's a straightforward, primarily highway-focused trip that's easy to complete in a single day. You'll find it a practical option for connecting these two points without significant detours.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
52.8 miles from Ruleville, MS
A natural place for your longest stop of the day
, about 1h 13m into the drive
.
Main Roads
Road
Distance
Duration
US 61
41.7 mi
48m
US 49
32.4 mi
42m
Highway 49
14.6 mi
21m
Goodman Road West
7 mi
10m
North Oak Avenue
6.9 mi
10m
US 51
1.6 mi
2m
West Floyce Street
0.3 mi
<1m
Whitworth Street
0.3 mi
<1m
Longest stretch:
US 61
— 41.7 mi, about 48m
Turn-by-Turn Driving Directions
Step-by-step road directions between Ruleville, MS and Southaven, MS.
1
Start on West Floyce Street
0.3 mi·35 sec·West Floyce Street
2
Turn left onto US 49W
6.9 mi·10 min·North Oak Avenue
3
Continue on US 49W
15 mi·21 min·Highway 49
4
At end of road, turn left onto US 49E
0.1 mi·11 sec·US 49E
5
Continue on US 49; MS 3
13 mi·19 min·US 49; MS 3
6
Take the ramp onto US 49
19 mi·23 min·US 49
7
Continue on US 61
42 mi·48 min·US 61
8
Take the exit
0.3 mi·42 sec
9
Keep slight right at fork
475 ft·13 sec
10
Turn straight onto MS 302
7.0 mi·10 min·Goodman Road West
11
Turn left onto US 51
1.6 mi·2 min·US 51
12
Turn right onto Whitworth Street
0.3 mi·43 sec·Whitworth Street
13
Turn right onto Moss Point Drive
0.2 mi·1 min·Moss Point Drive
14
At end of road, turn left onto Five Oaks Drive West
169 ft·7 sec·Five Oaks Drive West
15
Arrive at destination
Five Oaks Drive West
Trip Plan
Since this 2h 19m drive is easily manageable in a single day, you have the flexibility to depart whenever is most convenient. With a fuel cost estimated around $16, keeping your tank topped up won't be a major concern. The longest stretch without a planned stop is 41.7 miles, so plan your breaks accordingly, perhaps around the halfway mark. Keep an eye out for the transition onto US 49 and Highway 49 as you progress north.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 52.8 miles from Ruleville, MS, or about 1h 13m into the drive.
The longest continuous stretch on this route runs about 41.7 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 23 miles or 34m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 52.8 miles or 1h 13m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 52m
Traffic, exits, and arrival timing usually matter more near Southaven, MS than in the middle of the route.
Before You Leave
+
Open the route before leaving Ruleville, MS so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Ruleville, MS
This is one driving day of about 105.5 miles and 2h 19m.
Your first comfortable stop window is around 23 miles from Ruleville, MS.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on US 61 for about 41.7 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 7
5 decision points cluster between mile 0.3 and 105.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0.3 mi into trip|~0m in|US 49W / North Oak Avenue
Turn left onto US 49W / North Oak Avenue
Navigation decision point
4
21.8 mi into trip|~32m in|US 49E
At end of road, turn left onto US 49E
Navigation decision point
5
96.3 mi into trip|~2h 4m in
Keep slight right at fork
Highway fork - watch signs carefully
5
105.3 mi into trip|~2h 18m in|Moss Point Drive
Turn right onto Moss Point Drive
Navigation decision point
6
105.5 mi into trip|~2h 19m in|Five Oaks Drive West
At end of road, turn left onto Five Oaks Drive West
Complex interchange - multiple decisions in a short stretch
Fuel & Cost
Regular Gas
$15.93 one way
$31.87 round trip
$3.84/gal25.4 MPG avg37 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.21
$17.49
$34.98
premium
$4.56
$18.94
$37.87
diesel
$5.61
$23.29
$46.59
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$16
Meals
$25–$50
Total
$41–$66
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 36.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 68% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
31.7
0
$11.08
$5.06
Efficient EV
26.4
0
$9.23
$4.22
EV Truck/SUV
42.2
0
$14.77
$6.75
Gas CO2
37 kg
EV CO2
12 kg (68% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Ruleville, MS
Late night
in Ruleville on Tuesday
Local time
5:48 AM
CDT
Current temp
83°F
Unavailable
Live forecast
Destination
Southaven, MS
Late night
in Southaven on Tuesday
Local time
5:48 AM
CDT
Current temp
81°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 19m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Emmett Till and Mamie Till-Mobley National Monument
National Monument
In 1955, 14-year-old Emmett Till traveled to Money, Mississippi, to visit relatives. He was kidnapped, tortured, and murdered after reportedly whistling at a white woman. His mother, Mamie Till-Mobley...
4 mi from route
~11 min detour
Free
near mile 21.8
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a highway-focused drive for this 105.5-mile journey, with 86% of the route utilizing main roads like US 61, US 49, and Highway 49. The longest uninterrupted stretch you'll encounter is 41.7 miles on US 61. This means you'll experience mostly consistent driving speeds. The character of the drive remains largely consistent, emphasizing efficient travel over winding or scenic byways.
86% highway — fuel and pacing are the main things to plan.
15 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 41.7 mi on US 61.
How Hard Is This Drive?
2/10
This is a straightforward highway drive that stays mostly on US 61 and US 49. Navigation is very simple - set it and forget it for most of the drive. The trickiest moment comes around 0.3 miles in near US 49W / North Oak Avenue.
Driving Effort2/10
Very easy - short and simple to drive
Balances navigation complexity with total wheel time.
The drive from Ruleville, MS to Southaven, MS is easy. At 2h 19m with 86% highway, most drivers will find it relaxed and low-stress.
Where does it get tricky?
The main spots that need attention: at 0.3 miles (US 49W / North Oak Avenue): Navigation decision point; at 21.8 miles (US 49E): Navigation decision point; at 96.3 miles: Highway fork - watch signs carefully.
The longest stretch is about 41.7 miles on US 61. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: at 0.3 miles (US 49W / North Oak Avenue): Navigation decision point; at 21.8 miles (US 49E): Navigation decision point; at 96.3 miles: Highway fork - watch signs carefully.
Yes — Emmett Till and Mamie Till-Mobley National Monument. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Southaven, MS before heading back.
