Embarking from Reno, TX, to San Antonio, TX, this 382.8-mile journey spans approximately 6 hours and 53 minutes. The drive primarily utilizes the Purple Heart Trail and I-35, with a 59% highway share. Given the duration, this route is well-suited for a single-day trip, allowing you to reach your destination without needing an overnight stop. Expect a fuel cost of around $58 for this excursion through the Great Plains region of Texas. The overall feel of the drive is a practical transition between two points within the same state.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
191.4 miles from Reno, TX
A natural place for your longest stop of the day
, about 3h 25m into the drive
.
Step-by-step road directions between Reno, TX and San Antonio, TX.
1
Start on this road
161 ft·11 sec·this road
2
Turn sharp left onto US 82
2.7 mi·3 min·Lamar Road
3
Continue on US 82
0.1 mi·16 sec·Lamar Avenue
4
Turn left onto Southeast Loop 286
0.2 mi·19 sec·Southeast Loop 286
5
Merge onto US 271; Loop 286
4.8 mi·5 min·Southeast Loop 286
6
Continue on Loop 286
0.1 mi·9 sec·Southwest Loop 286
7
Take the exit
0.1 mi·24 sec
Toward TX 19, TX 24: Cooper, Sulphur Springs
8
Turn left onto TX 19; TX 24
46 mi·50 min·South Church Street
9
Take the exit
0.4 mi·30 sec
Toward I 30 West: Dallas
10
Merge onto I 30; US 67
55 mi·59 min·I 30; US 67
Use the straight / slight right lanes.
11
Take the exit
0.6 mi·1 min
Exit 46AToward I 35E: Denton, WacoUse the straight / slight right lanes.
12
Keep slight left at fork
0.1 mi·14 sec
Toward I 35E South, I 35E North: Waco, Denton
13
Keep slight left at fork
221 ft·5 sec
Toward I 35E North, I 35E South: Denton, WacoUse the straight / slight right lanes.
14
Keep slight left at fork
0.4 mi·30 sec
Toward I 35E South: WacoUse the left / right lanes.
15
Continue on I 35E
0.5 mi·44 sec·South R L Thornton Freeway
16
Continue on I 35E
89 mi·1 hr 31 min·South R L Thornton Freeway
Exit 426Toward Dallas ZooUse the straight / slight right lanes.
17
Continue on I 35; US 77
6.6 mi·7 min·North Jack Kultgen Expressway
Use the straight / slight right lanes.
18
Continue on I 35
38 mi·39 min·Purple Heart Trail
Use the straight / slight right lanes.
19
Keep slight left at fork onto I 35
56 mi·58 min·I 35
Use the straight / slight right lanes.
20
Keep slight left at fork onto I 35; US 290
50 mi·54 min·Purple Heart Trail
Toward 32nd Street, Dean Keeton StreetUse the slight left lane.
21
Continue on I 35
1.7 mi·1 min·Interstate Highway 35
Use the straight / slight right lanes.
22
Continue on I 35
12 mi·12 min·Purple Heart Trail
Use the straight / slight right lanes.
23
Continue on I 35
10.0 mi·11 min·North Pan Am Expressway
Use the straight / slight right lanes.
24
Keep slight left at fork onto I 35
6.4 mi·8 min·North Pan Am Expressway
Toward I 35 SouthUse the straight / slight right lanes.
25
Keep slight left at fork onto I 35
0.6 mi·41 sec·North Pan Am Expressway
Toward I 35 South: Lower Level, LaredoUse the slight left lane.
26
Take the exit
0.1 mi·16 sec
Exit 157AToward Lexington Avenue, Main Avenue, San Pedro AvenueUse the slight right lane.
27
Turn straight onto East Elmira Street
526 ft·17 sec·East Elmira Street
Use the left / straight lanes.
28
Turn left onto North Main Avenue
0.2 mi·18 sec·North Main Avenue
Use the left / straight lanes.
29
Enter roundabout onto Navarro Street
159 ft·3 sec·Navarro Street
30
Continue on Navarro Street
111 ft·2 sec·Navarro Street
31
Keep slight right at fork onto North Main Avenue
0.4 mi·51 sec·North Main Avenue
Use the slight left / slight right lanes.
32
Turn right onto West Travis Street
222 ft·10 sec·West Travis Street
33
Turn left onto North Flores Street
0.2 mi·20 sec·North Flores Street
34
Continue on Military Plaza
392 ft·15 sec·Military Plaza
35
Turn left onto Dolorosa Street
327 ft·8 sec·Dolorosa Street
36
Arrive at destination
Dolorosa Street
Trip Plan
To make the most of your 6-hour and 53-minute drive from Reno to San Antonio, consider an early morning departure to maximize daylight and avoid potential afternoon traffic. With a total of 382.8 miles, one planned stop should be sufficient for a break. Keep an eye on your fuel gauge, as the estimated cost is $58, and plan your refueling accordingly, especially during the longest stretch of 99.6 miles on the Purple Heart Trail. This route is manageable in a single day, offering flexibility in your pacing.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 191.4 miles from Reno, TX, or about 3h 25m into the drive.
The longest continuous stretch on this route runs about 99.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 84 miles or 1h 32m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 191.4 miles or 3h 25m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 5h 44m
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Before You Leave
+
Open the route before leaving Reno, TX so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Reno, TX
This is one driving day of about 382.8 miles and 6h 53m.
Your first comfortable stop window is around 84 miles from Reno, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Purple Heart Trail for about 99.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 24
5 decision points cluster between mile 109.9 and 381.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
8
109.9 mi into trip|~2h in
Take the exit toward I 35E: Denton, Waco
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 46A
Toward I 35E: Denton, Waco
9
110.6 mi into trip|~2h 2m in
Keep slight left at fork toward I 35E North, I 35E South: Denton, Waco
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Toward I 35E North, I 35E South: Denton, Waco
8
301.2 mi into trip|~5h 20m in|I 35; US 290 / Purple Heart Trail
Keep slight left at fork onto I 35; US 290 / Purple Heart Trail toward 32nd Street, Dean Keeton Street
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward 32nd Street, Dean Keeton Street
8
381 mi into trip|~6h 49m in|I 35 / North Pan Am Expressway
Keep slight left at fork onto I 35 / North Pan Am Expressway toward I 35 South: Lower Level, Laredo
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight left lane.
Toward I 35 South: Lower Level, Laredo
8
381.6 mi into trip|~6h 50m in
Take the exit toward Lexington Avenue, Main Avenue, San Pedro Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 157A
Toward Lexington Avenue, Main Avenue, San Pedro...
Fuel & Cost
Regular Gas
$57.84 one way
$115.68 round trip
$3.84/gal25.4 MPG avg134 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.20
$63.31
$126.63
premium
$4.54
$68.35
$136.69
diesel
$5.61
$84.52
$169.03
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$58
Meals
$25–$50
Total
$83–$108
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 133.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $40 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
114.8
1
$40.19
$18.37
Efficient EV
95.7
1
$33.50
$15.31
EV Truck/SUV
153.1
1
$53.59
$24.50
Gas CO2
134 kg
EV CO2
45 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Reno, TX
Late night
in Reno on Tuesday
Local time
4:03 AM
CDT
Current temp
78°F
Unavailable
Live forecast
Destination
San Antonio, TX
Late night
in San Antonio on Tuesday
Local time
4:03 AM
CDT
Current temp
70°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
8 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
6h 53m on the road
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Waco Mammoth National Monument
National Monument
Standing as tall as 14 feet and weighing 20,000 pounds, Columbian mammoths roamed across what is present-day Texas thousands of years ago. Today, the fossil specimens represent the nation's first and...
Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...
9 mi from route
~22 min detour
Free
near mile 382.8
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive offers a mixed experience, transitioning between different types of roads. With 59% of the route on highways, you'll encounter stretches of faster travel, interspersed with other road types. The longest uninterrupted stretch you'll navigate is 99.6 miles along the Purple Heart Trail. This suggests a varied driving profile, rather than a constant interstate grind, potentially offering a more dynamic journey as you progress south.
59% highway, the rest on surface roads — varied driving throughout.
36 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 99.6 mi on Purple Heart Trail.
How Hard Is This Drive?
9/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 109.9 miles in.
Driving Effort9/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 24 significant decision points across 382.8 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 109.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 110.6 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 301.2 miles (I 35; US 290 / Purple Heart Trail): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Reno, TX and San Antonio, TX, road signs point toward Waco, Denton and Dallas Zoo.
San Antonio is the second largest city in the state of Texas and the 7th largest in the United States. It's the 24th largest metropolitan area in the country. Visited by more than 31 million annual visitors, San Antonio is a beautiful city at the axis of three different geological terrains: Hill Country, South Texas Plains and Prairie and Lakes. There's a lot to do in this city: fine art museums, historical missions and plenty of amusement parks in addition to great dining and lots of drinking. The culture and people are vibrant and interesting. San Antonio's downtown is one of the most lively in the nation.
Top landmarks
•Alamo Mission in San Antonio — historic place in San Antonio, Bexar County, Texas
•San Antonio Missions National Historical Park — historic district in San Antonio, Bexar County, Texas
•Fort Sam Houston — military base in San Antonio, Texas
Doable as a same-day drive at 6h 53m. Total distance: 382.8 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
6h 53m drive, plan rest stops for pacing.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 99.6 miles on Purple Heart Trail. The full list of main roads is in the Roads section above.
Yes — we found about 37 rest areas or service plazas within a short detour of the route (from OpenStreetMap). See the Rest Stops tab under Nearby Places for locations and mile markers. Plan to stretch, use the bathroom, and top off fluids every 2–3 hours on longer drives.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at San Antonio, TX before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. There are 37 rest areas along the route for bathroom stops.
The main spots that need attention: at 109.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 110.6 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 301.2 miles (I 35; US 290 / Purple Heart Trail): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Waco Mammoth National Monument and San Antonio Missions National Historical Park. See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 6.9 hours each way, a round trip means 13.8 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at San Antonio, TX before the return drive.
