Pittsburgh to Nazareth is 295.9 miles and takes about 5h 51m via Pennsylvania Turnpike, with a fuel budget near $49 and enough daylight to finish in a day. This drive stays within Pennsylvania, connecting the western part of the state to the eastern Lehigh Valley region. It's a fairly direct trip, primarily utilizing major highways, making it a straightforward option for a single-day journey. Consider this route if you're looking for efficiency and don't need to make extensive detours.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
147.9 miles from Pittsburgh, PA
A natural place for your longest stop of the day
, about 2h 49m into the drive
.
Main Roads
Road
Distance
Duration
Pennsylvania Turnpike
170.5 mi
3h 7m
William Penn Highway
42.8 mi
50m
American Legion Memorial Highway
22.5 mi
27m
Lehigh Valley Thruway
15.1 mi
20m
Penn-Lincoln Parkway East
13.6 mi
18m
I 81
12.7 mi
15m
78th Division Highway
7.6 mi
8m
Nazareth Pike
4.1 mi
6m
Longest stretch:
Pennsylvania Turnpike
— 170.5 mi, about 3h 7m
Turn-by-Turn Driving Directions
Step-by-step road directions between Pittsburgh, PA and Nazareth, PA.
1
Start on Grant Street
45 ft·9 sec·Grant Street
2
Continue on Grant Street
0.3 mi·1 min·Grant Street
3
Take the ramp
0.4 mi·50 sec
Toward I 376 East: Monroeville
4
Merge onto I 376; US 22; US 30
14 mi·18 min·Penn-Lincoln Parkway East
Use the straight / slight right lanes.
5
Take the exit
0.2 mi·1 min
Exit 85Toward I 76, PATP: Ohio, Harrisburg
6
Continue on this road
0.2 mi·30 sec·this road
Use the straight lane.
7
Keep slight right at fork
0.2 mi·29 sec
Toward I 76 East: HarrisburgUse the slight right lane.
8
Merge onto I 76; PATP
170 mi·3 hr 7 min·Pennsylvania Turnpike
9
Take the exit
0.9 mi·2 min
Toward I 81, US 11: Carlisle, HarrisburgUse the slight right lane.
10
Keep slight left at fork
0.3 mi·54 sec
Toward US 11 North: HarrisburgUse the straight / slight right lanes.
11
Continue on US 11
1.1 mi·2 min·Harrisburg Pike
Use the straight lane.
12
Take the exit
0.3 mi·34 sec
Toward I 81 North: Harrisburg
13
Merge onto I 81
13 mi·15 min·I 81
Use the straight / right lanes.
14
Take the exit
0.2 mi·14 sec
Toward US 11, US 15: Enola, Marysville
15
Keep slight left at fork
0.3 mi·28 sec
Toward US 11 North, US 15 North: Marysville
16
Keep slight left at fork
0.4 mi·32 sec
17
Merge onto I 81
0.7 mi·1 min·George N. Wade Memorial Bridge
Use the straight / slight right lanes.
18
Continue on I 81
3.4 mi·4 min·American Legion Memorial Highway
19
Keep slight left at fork onto I 81
19 mi·22 min·American Legion Memorial Highway
Use the straight / slight right lanes.
20
Take the exit
0.7 mi·45 sec
Exit 89Toward I 78 East: Allentown
21
Continue on I 78
7.6 mi·8 min·78th Division Highway
22
Continue on I 78; US 22
43 mi·50 min·William Penn Highway
Use the straight lane.
23
Keep slight right at fork onto US 22
15 mi·20 min·Lehigh Valley Thruway
Exit 51Toward US 22 East: Pennsylvania Turnpike, LVI AirportUse the slight right lane.
24
Take the exit
0.2 mi·43 sec
Toward PA 191: Nazareth PikeUse the slight right lane.
25
Turn right onto PA 191
4.1 mi·6 min·Nazareth Pike
Use the straight lane.
26
Turn right onto PA 191; PA 248
0.2 mi·37 sec·Easton Road
27
Turn left onto PA 191
0.5 mi·48 sec·South Broad Street
28
Arrive at destination
PA 191
Trip Plan
Given the 5h 51m estimated drive time, leaving Pittsburgh in the morning should allow ample time to reach Nazareth before evening. The route has a recommended single stop, so plan for a mid-drive break to stretch your legs. Keep an eye on your fuel levels, as the longest stretch without a change in primary road is over 170 miles. The $49 fuel cost estimate is based on the total distance, so factor that into your budget, and remember that highway tolls are not included in this estimate.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 147.9 miles from Pittsburgh, PA, or about 2h 49m into the drive.
The longest continuous stretch on this route runs about 170.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 65 miles or 1h 18m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 147.9 miles or 2h 49m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 42m
Traffic, exits, and arrival timing usually matter more near Nazareth, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Pittsburgh, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Pittsburgh, PA
This is one driving day of about 295.9 miles and 5h 51m.
Your first comfortable stop window is around 65 miles from Pittsburgh, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Pennsylvania Turnpike for about 170.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 22
5 decision points cluster between mile 14.3 and 275.8 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
14.3 mi into trip|~20m in
Take the exit toward I 76, PATP: Ohio, Harrisburg
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Exit 85
Toward I 76, PATP: Ohio, Harrisburg
8
14.7 mi into trip|~22m in
Keep slight right at fork toward I 76 East: Harrisburg
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight right lane.
Toward I 76 East: Harrisburg
7
185.3 mi into trip|~3h 30m in
Take the exit toward I 81, US 11: Carlisle, Harrisburg
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward I 81, US 11: Carlisle, Harrisburg
7
186.2 mi into trip|~3h 32m in
Keep slight left at fork toward US 11 North: Harrisburg
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward US 11 North: Harrisburg
9
275.8 mi into trip|~5h 21m in|US 22 / Lehigh Valley Thruway
Keep slight right at fork onto US 22 / Lehigh Valley Thruway toward US 22 East: Pennsylvania Turnpike, LVI Airport
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 51
Toward US 22 East: Pennsylvania Turnpike, LVI A...
Fuel & Cost
Regular Gas
$49.06 one way
$98.11 round trip
$4.21/gal25.4 MPG avg104 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.61
$53.73
$107.46
premium
$4.93
$57.39
$114.77
diesel
$5.61
$65.33
$130.66
Estimated Tolls: $23.22
Pennsylvania Turnpike
(170.5 mi)$22.16
Lehigh Valley Thruway
(15.1 mi)$1.06
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$49
Tolls
$23
Meals
$25–$50
Total
$97–$122
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 103.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $31 in charging
· 1 stop
· 66% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
88.8
1
$31.07
$14.20
Efficient EV
74
0
$25.89
$11.84
EV Truck/SUV
118.4
1
$41.43
$18.94
Gas CO2
104 kg
EV CO2
35 kg (66% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 19, 2026
Origin
Pittsburgh, PA
Late night
in Pittsburgh on Sunday
Local time
5:55 AM
EDT
Current temp
73°F
Unavailable
Live forecast
Destination
Nazareth, PA
Late night
in Nazareth on Sunday
Local time
5:55 AM
EDT
Current temp
68°F
Unavailable
Live forecast
54°F
Hancock, MD
148 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
5 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
5h 51m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Carlisle Federal Indian Boarding School National Monument
National Monument
More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...
1 mi from route
~2 min detour
Free
near mile 183.6
The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...
5 mi from route
~13 min detour
Free
near mile 224.5
On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...
7 mi from route
~18 min detour
Free
near mile 81.6
The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...
24 mi from route
~59 min detour
Free
near mile 102
The battle at Fort Necessity in the summer of 1754 was the opening action of the French and Indian War. This war was a clash of British, French and American Indian cultures. It ended with the removal...
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This is a highway-focused drive, with 67% of the route utilizing major roadways. You'll spend a significant portion of your time on the Pennsylvania Turnpike, including one uninterrupted stretch of 170.5 miles. The journey begins with the Pennsylvania Turnpike and transitions to sections of the William Penn Highway and American Legion Memorial Highway. Expect a consistent pace for most of the drive, with the landscape unfolding primarily from the highway perspective.
67% highway — fuel and pacing are the main things to plan.
28 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 170.5 mi on Pennsylvania Turnpike.
How Hard Is This Drive?
10/10
This is a straightforward highway drive that stays mostly on Pennsylvania Turnpike and William Penn Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 14.3 miles in.
Driving Effort10/10
High effort - long or complex enough to need steady focus all day
Balances navigation complexity with total wheel time.
This is a demanding drive. With 22 significant decision points across 295.9 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 14.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 14.7 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 185.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Pittsburgh, PA and Nazareth, PA, road signs point toward Harrisburg, Marysville and Lvi Airport.
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
Doable as a same-day drive at 5h 51m. Total distance: 295.9 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 51m drive, comfortable solo distance.
Frequently Asked Questions
The longest stretch is about 170.5 miles on Pennsylvania Turnpike. The full list of main roads is in the Roads section above.
Expect about $23.22 in tolls one way, starting with Pennsylvania Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Nazareth, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 14.3 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 14.7 miles: Highway fork - watch signs carefully. Lane positioning matters here; at 185.3 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Carlisle Federal Indian Boarding School National Monument, Appalachian National Scenic Trail and Flight 93 National Memorial (5 total within detour distance). See the National Parks section for detour distances and tips on detours.
Not recommended in a single day. At 5.9 hours each way, a round trip means 11.7 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Nazareth, PA before the return drive.
