Pittsburgh to Middleburg is 198 miles and takes about 4 hours 17 minutes via William Penn Highway and I-99, with a fuel budget near $33 and enough daylight to finish in a day. This trip takes you across Pennsylvania, moving from the Northeast region to another part of the Northeast. The drive offers a mixed driving experience, suggesting you'll encounter both highway speeds and potentially slower local roads. Given its manageable duration, this route is well-suited for a single-day journey, making it a practical option if you're looking for a relatively straightforward drive between these two points.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
99 miles from Pittsburgh, PA
A natural place for your longest stop of the day
, about 2h 17m into the drive
.
Main Roads
Road
Distance
Duration
William Penn Highway
61.6 mi
1h 25m
I 99
44.9 mi
49m
South Walnut Street
31.1 mi
36m
General Potter Highway
21.5 mi
28m
Penn-Lincoln Parkway East
13.8 mi
19m
Admiral Peary Highway
13.7 mi
19m
Mount Nittany Expressway
6.2 mi
8m
Boal Avenue
2.6 mi
4m
Longest stretch:
William Penn Highway
— 61.6 mi, about 1h 25m
Turn-by-Turn Driving Directions
Step-by-step road directions between Pittsburgh, PA and Middleburg, PA.
1
Start on Grant Street
45 ft·9 sec·Grant Street
2
Continue on Grant Street
0.3 mi·1 min·Grant Street
3
Take the ramp
0.4 mi·50 sec
Toward I 376 East: Monroeville
4
Merge onto I 376; US 22; US 30
14 mi·19 min·Penn-Lincoln Parkway East
Use the straight / slight right lanes.
5
Merge onto US 22
45 mi·1 hr 5 min·William Penn Highway
Use the straight / right lanes.
6
Continue on US 22
14 mi·19 min·Admiral Peary Highway
Use the straight / right lanes.
7
Continue on US 22
17 mi·19 min·William Penn Highway
8
Continue on this road
0.5 mi·45 sec·this road
Toward I 99, US 220: Altoona, Bedford
9
Keep slight left at fork
0.9 mi·1 min
Toward I 99 North, US 220 North: Altoona
10
Merge onto I 99; US 220
41 mi·44 min·I 99; US 220
11
Keep slight left at fork onto I 99; US 220; US 322
4.0 mi·4 min·I 99; US 220; US 322
Use the straight lane.
12
Keep slight right at fork onto US 322
6.2 mi·8 min·Mount Nittany Expressway
Exit 73Toward US 322 East: Penn State University, State College
13
Continue on US 322; PA 144 Truck
2.6 mi·4 min·Boal Avenue
Use the straight lane.
14
Continue on US 322; PA 144 Truck
22 mi·28 min·General Potter Highway
15
Take the exit onto US 522
0.2 mi·32 sec·US 522
Toward US 522 North: Selinsgrove
16
Turn left onto US 522
31 mi·36 min·South Walnut Street
17
Turn right onto South Charles Street
0.2 mi·55 sec·South Charles Street
18
At end of road, turn right onto Edmond Avenue
168 ft·7 sec·Edmond Avenue
19
Arrive at destination
Edmond Avenue
Trip Plan
For this 4-hour, 17-minute drive, leaving Pittsburgh in the morning will allow you ample time to reach Middleburg before evening. With only one recommended stop and a fuel cost estimated at $33, you can plan your budget accordingly. Keep an eye on your fuel gauge, especially before entering longer stretches like the 61.6-mile segment on the William Penn Highway, as services can sometimes be spaced out. The mixed nature of the drive means being prepared for both efficient highway cruising and potentially slower speeds on local roads.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 99 miles from Pittsburgh, PA, or about 2h 17m into the drive.
The longest continuous stretch on this route runs about 61.6 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 44 miles or 1h 4m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 99 miles or 2h 17m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 34m
Traffic, exits, and arrival timing usually matter more near Middleburg, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Pittsburgh, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Pittsburgh, PA
This is one driving day of about 198 miles and 4h 17m.
Your first comfortable stop window is around 44 miles from Pittsburgh, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on William Penn Highway for about 61.6 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 12
5 decision points cluster between mile 0.7 and 136 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.7 mi into trip|~2m in|I 376; US 22; US 30 / Penn-Lincoln Parkway East
Merge onto I 376; US 22; US 30 / Penn-Lincoln Parkway East
Merge point - match speed before joining. Lane positioning matters here
Use the straight / slight right lanes.
5
14.5 mi into trip|~21m in|US 22 / William Penn Highway
Merge onto US 22 / William Penn Highway
Merge point - match speed before joining. Lane positioning matters here
Use the straight / right lanes.
6
90.2 mi into trip|~2h 7m in
Keep slight left at fork toward I 99 North, US 220 North: Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Toward I 99 North, US 220 North: Altoona
6
132.1 mi into trip|~2h 53m in|I 99; US 220; US 322
Keep slight left at fork onto I 99; US 220; US 322
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
7
136 mi into trip|~2h 57m in|US 322 / Mount Nittany Expressway
Keep slight right at fork onto US 322 / Mount Nittany Expressway toward US 322 East: Penn State University, State College
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Exit 73
Toward US 322 East: Penn State University, Stat...
Fuel & Cost
Regular Gas
$32.83 one way
$65.65 round trip
$4.21/gal25.4 MPG avg69 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.61
$35.95
$71.90
premium
$4.93
$38.40
$76.80
diesel
$5.61
$43.72
$87.43
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$33
Meals
$25–$50
Total
$58–$83
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 69.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $21 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
59.4
0
$20.79
$9.50
Efficient EV
49.5
0
$17.33
$7.92
EV Truck/SUV
79.2
0
$27.72
$12.67
Gas CO2
69 kg
EV CO2
23 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 18, 2026
Origin
Pittsburgh, PA
Late night
in Pittsburgh on Tuesday
Local time
5:03 AM
EDT
Current temp
85°F
Partly Sunny then Showers And Thunderstorms
S 6 to 16 mph80% chanceLive forecast
Destination
Middleburg, PA
Late night
in Middleburg on Tuesday
Local time
5:03 AM
EDT
Current temp
53°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
32 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
4h 17m on the road
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Johnstown Flood National Memorial
National Memorial
The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...
7 mi from route
~18 min detour
Free
near mile 68.3
On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...
26 mi from route
~65 min detour
Free
near mile 61.4
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This route presents a mixed driving profile, with 33% of it being highway driving. You'll experience stretches on the William Penn Highway, including a significant 61.6-mile segment without interruption, likely offering a more consistent pace. The inclusion of I-99 suggests periods of faster, more direct travel, characteristic of interstate highways. As you progress, expect the character of the drive to shift between these faster sections and potentially more varied local road conditions, requiring you to adapt your driving style throughout the 198-mile journey.
33% highway, the rest on surface roads — varied driving throughout.
19 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 61.6 mi on William Penn Highway.
How Hard Is This Drive?
7/10
This route mixes highway mileage with some local-road sections near the start or finish. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.7 miles in near I 376; US 22; US 30 / Penn-Lincoln Parkway East.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 12 significant decision points across 198 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.7 miles (I 376; US 22; US 30 / Penn-Lincoln Parkway East): Merge point - match speed before joining. Lane positioning matters here; at 14.5 miles (US 22 / William Penn Highway): Merge point - match speed before joining. Lane positioning matters here; at 90.2 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Pittsburgh, PA and Middleburg, PA, road signs point toward Bedford and State College.
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
Top landmarks
•Carnegie Museum of Natural History — natural history museum in Pittsburgh, Pennsylvania, United States
•Allegheny Observatory — historic observatory of the University of Pittsburgh
•Carnegie Museum of Art — museum in Pittsburgh, Pennsylvania
Doable as a same-day drive at 4h 17m. Total distance: 198 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 17m drive, comfortable solo distance.
Scenic Drive
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 61.6 miles on William Penn Highway. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Middleburg, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 0.7 miles (I 376; US 22; US 30 / Penn-Lincoln Parkway East): Merge point - match speed before joining. Lane positioning matters here; at 14.5 miles (US 22 / William Penn Highway): Merge point - match speed before joining. Lane positioning matters here; at 90.2 miles: Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Yes — Johnstown Flood National Memorial and Flight 93 National Memorial. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.3 hours each way, an in-and-out day trip would put you behind the wheel for 8.6 hours — manageable with a long break at Middleburg, PA, but most travelers stay overnight.
