Stretching 205.5 miles across the Texas landscape, this drive from Ozona to San Antonio is a straightforward journey typically lasting about 3 hours and 2 minutes. Because the route stays entirely within the Great Plains, you can expect a consistent regional feel throughout your travel. Budgeting approximately $31 for fuel should cover your needs for the one-day trip. Since the total transit time is quite manageable, there is no need to split this into an overnight excursion. It serves as a practical, efficient connection between these two Texas points, allowing you to reach your destination well within a single day of driving.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
102.8 miles from Ozona, TX
A natural place for your longest stop of the day
, about 1h 39m into the drive
.
Main Roads
Road
Distance
Duration
I 10
201.5 mi
3h 16m
McDermott Freeway
1.7 mi
2m
North Pecos-La Trinidad
0.7 mi
1m
Dolorosa Street
0.5 mi
<1m
Avenue E
0.3 mi
<1m
15th Street
0.3 mi
<1m
11th Street
<0.1 mi
<1m
Avenue D
<0.1 mi
<1m
Longest stretch:
I 10
— 201.5 mi, about 3h 16m
Turn-by-Turn Driving Directions
Step-by-step road directions between Ozona, TX and San Antonio, TX.
1
Start on Avenue D
10 ft·5 sec·Avenue D
2
Turn left onto Loop 466
264 ft·12 sec·11th Street
3
Turn left onto TX 163
0.3 mi·41 sec·Avenue E
4
Turn left onto 15th Street
0.3 mi·29 sec·15th Street
5
Take the ramp
0.1 mi·17 sec
Toward I 10 East: San Antonio
6
Merge onto I 10
184 mi·2 hr 56 min·I 10
Use the straight / slight right lanes.
7
Keep slight right at fork onto I 10; US 87
17 mi·19 min·I 10; US 87
Use the straight / slight right lanes.
8
Keep slight right at fork onto I 10; US 87
1.7 mi·2 min·McDermott Freeway
9
Take the exit
0.5 mi·1 min
Exit 569CToward Santa Rosa Street, DowntownUse the slight right lane.
10
Turn straight onto North Pecos-La Trinidad
0.2 mi·16 sec·North Pecos-La Trinidad
11
Keep slight right at fork onto North Pecos-La Trinidad
0.6 mi·1 min·North Pecos-La Trinidad
Use the straight lane.
12
Turn left onto Dolorosa Street
0.5 mi·55 sec·Dolorosa Street
Use the straight / left lanes.
13
Arrive at destination
Dolorosa Street
Trip Plan
Since this is a turn-heavy local route, plan to start your drive during daylight hours to ensure maximum visibility through the winding sections. Given the 205.5-mile distance, you have the flexibility to make the trip in one go, but keeping a water supply in the car is a wise move for any Texas road trip. You will not have the benefit of high-speed interstate segments to cover ground quickly, so factor in a bit of extra time if you encounter local traffic. Your best strategy is to check your fuel levels before leaving Ozona, as the local road nature of this drive may make frequent stops less convenient. Staying alert to the curves is the most important factor for a smooth arrival in San Antonio.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 102.8 miles from Ozona, TX, or about 1h 39m into the drive.
The longest continuous stretch on this route runs about 201.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 45 miles or 44m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 102.8 miles or 1h 39m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 42m
Traffic, exits, and arrival timing usually matter more near San Antonio, TX than in the middle of the route.
Before You Leave
+
Open the route before leaving Ozona, TX so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Ozona, TX
This is one driving day of about 205.6 miles and 3h 23m.
Your first comfortable stop window is around 45 miles from Ozona, TX.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on I 10 for about 201.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 0 and 205.1 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0 mi into trip|~0m in|Loop 466 / 11th Street
Turn left onto Loop 466 / 11th Street
Navigation decision point
6
184.8 mi into trip|~2h 58m in|I 10; US 87
Keep slight right at fork onto I 10; US 87
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
8
203.9 mi into trip|~3h 19m in
Take the exit toward Santa Rosa Street, Downtown
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Exit 569C
Toward Santa Rosa Street, Downtown
6
204.6 mi into trip|~3h 21m in|North Pecos-La Trinidad
Keep slight right at fork onto North Pecos-La Trinidad
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
6
205.1 mi into trip|~3h 22m in|Dolorosa Street
Turn left onto Dolorosa Street
Lane positioning matters here
Use the straight / left lanes.
Fuel & Cost
Regular Gas
$31.07 one way
$62.13 round trip
$3.84/gal25.4 MPG avg72 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.20
$34.00
$68.01
premium
$4.54
$36.71
$73.42
diesel
$5.61
$45.39
$90.79
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$31
Meals
$25–$50
Total
$56–$81
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 71.9 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $22 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
61.7
0
$21.59
$9.87
Efficient EV
51.4
0
$17.99
$8.22
EV Truck/SUV
82.2
1
$28.78
$13.16
Gas CO2
72 kg
EV CO2
24 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Ozona, TX
Morning
in Ozona on Sunday
Local time
6:32 AM
CDT
Current temp
58°F
Unavailable
Live forecast
Destination
San Antonio, TX
Morning
in San Antonio on Sunday
Local time
6:32 AM
CDT
Current temp
77°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
19 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 23m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
San Antonio Missions National Historical Park
National Historical Park
Welcome to San Antonio Missions, a National Park Service site and the only UNESCO World Heritage Site in Texas. Each mission in the park is a center of community and has been since the early 1700s. Th...
9 mi from route
~22 min detour
Free
near mile 205.6
Lyndon B. Johnson National Historical Park tells the story of our 36th president beginning with his ancestors until his final resting place on his beloved LBJ Ranch. This entire "circle of life" gives...
26 mi from route
~66 min detour
Free
near mile 156
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
Expect a turn-heavy local drive rather than a monotonous interstate cruise on this journey. Because the route has a highway share of 0%, your time behind the wheel will be spent navigating local roads that demand more active steering and attention. You will experience a winding, technical rhythm that differs significantly from the fast-paced highway stretches found elsewhere in the state. This path rewards drivers who prefer a hands-on, engaging experience over long, straight corridors. Prepare for a road that feels more intimate and local as you transition between your starting point and the city of San Antonio.
99% highway — fuel and pacing are the main things to plan.
13 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 201.5 mi on I 10.
How Hard Is This Drive?
6/10
This is a straightforward highway drive that stays mostly on I 10 and McDermott Freeway. You will hit about 10 points where you need to pay attention to lane position or signs. The trickiest moment comes early in the drive near Loop 466 / 11th Street.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 205.6 miles you will encounter 10 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: near the start (Loop 466 / 11th Street): Navigation decision point; at 184.8 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 203.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Ozona, "The Biggest Little Town in the World," is an unincorporated town in Texas, about an hour south-west of San Angelo. It is the county seat (in fact, sole town) of Crockett County.
San Antonio is the second largest city in the state of Texas and the 7th largest in the United States. It's the 24th largest metropolitan area in the country. Visited by more than 31 million annual visitors, San Antonio is a beautiful city at the axis of three different geological terrains: Hill Country, South Texas Plains and Prairie and Lakes. There's a lot to do in this city: fine art museums, historical missions and plenty of amusement parks in addition to great dining and lots of drinking. The culture and people are vibrant and interesting. San Antonio's downtown is one of the most lively in the nation.
Top landmarks
•Alamo Mission in San Antonio — historic place in San Antonio, Bexar County, Texas
•San Antonio Missions National Historical Park — historic district in San Antonio, Bexar County, Texas
•Fort Sam Houston — military base in San Antonio, Texas
Doable as a same-day drive at 3h 23m. Total distance: 205.6 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 23m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (99%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 201.5 miles on I 10. The full list of main roads is in the Roads section above.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at San Antonio, TX before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: near the start (Loop 466 / 11th Street): Navigation decision point; at 184.8 miles (I 10; US 87): Highway fork - watch signs carefully. Lane positioning matters here; at 203.9 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — San Antonio Missions National Historical Park and Lyndon B Johnson National Historical Park. See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 3.4 hours each way, an in-and-out day trip would put you behind the wheel for 6.8 hours — manageable with a long break at San Antonio, TX, but most travelers stay overnight.
