Origin
Natchez, MS
Late night in Natchez on Sunday
Local time
2:56 AM
CDT
Current temp
79°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
4h 40m
Distance
241.3 mi
388 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$36
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Natchez, MS
Wikimedia Commons
Starkville, MS
Wikimedia Commons
This 241.3-mile journey from Natchez to Starkville, Mississippi, is a solid day trip, taking approximately 4 hours and 40 minutes. Primarily following MS Hwy 25, I-55, and US 84, this route is heavily highway-focused, with 93% of the drive on faster roads. With an estimated fuel cost of $36, it's an economical option for a single-day adventure within the Southeast region. The drive is designed for efficient travel, making it ideal for getting from point A to point B without extensive detours. Consider this a straightforward drive that prioritizes time on the road.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
120.6 miles from Natchez, MS
A natural place for your longest stop of the day , about 2h 18m into the drive .
| Road | Distance | Duration |
|---|---|---|
| MS Hwy 25 | 79.6 mi | 1h 30m |
| I 55 | 59.5 mi | 1h 4m |
| US 84 | 53.2 mi | 1h 1m |
| MS 25 | 27.8 mi | 32m |
| Lakeland Drive | 12.3 mi | 14m |
| US 61 | 3.3 mi | 3m |
| MS 12 | 2.2 mi | 4m |
| Devereaux Drive | 1.3 mi | 2m |
Step-by-step road directions between Natchez, MS and Starkville, MS.
Start on South Pearl Street
Turn right onto Franklin Street
Turn slight left onto Devereaux Drive
Take the ramp onto Devereaux Drive
Merge onto US 61; US 84
Take the exit onto US 84
Take the exit
Merge onto I 55
Keep slight right at fork onto I 55
Keep slight left at fork onto I 55
Take the exit
Turn right onto MS 25
Continue on MS 25
Take the exit onto MS 25
Keep slight right at fork onto MS 25
Continue on MS 25
Take the exit
Turn left onto MS 12
Turn right onto Eckford Drive
Continue on Victory Lane
Turn right
Turn right
Arrive at destination
Given the 4-hour 40-minute duration, starting your drive from Natchez in the morning is advisable to reach Starkville comfortably within the same day. With only one suggested stop, plan your breaks strategically, especially during the longest stretch of 79.6 miles on MS Hwy 25, where services might be less frequent. The $36 fuel cost is manageable, but it's always wise to start with a full tank. Keep an eye on your fuel gauge, particularly before embarking on that extended section of MS Hwy 25 to ensure you have ample range.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 53 miles or 1h 3m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 120.6 miles or 2h 18m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 46m
Traffic, exits, and arrival timing usually matter more near Starkville, MS than in the middle of the route.
Open the route before leaving Natchez, MS so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Natchez, MS
This is one driving day of about 241.3 miles and 4h 40m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
121 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 53 miles helps settle the day before fatigue starts building.
The midpoint is around 120.6 miles from Natchez, MS, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before MS Hwy 25 if your tank is already low. That segment runs about 79.6 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 0.1 and 238.5 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Turn right onto Franklin Street
Navigation decision point
Keep slight right at fork onto I 55
Highway fork - watch signs carefully
Keep slight left at fork onto I 55 toward Grenada, Memphis
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork onto MS 25
Highway fork - watch signs carefully. Lane positioning matters here
Take the exit toward MS 12: Starkville, Ackerman
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Regular Gas
$36.44 one way
$72.88 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.21 | $40.00 | $80.01 |
| premium | $4.56 | $43.31 | $86.62 |
| diesel | $5.61 | $53.28 | $106.55 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$36
Meals
$25–$50
Total
$61–$86
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 84.4 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $25 in charging · 0 stops · 67% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 72.4 | 0 | $25.34 | $11.58 |
| Efficient EV | 60.3 | 0 | $21.11 | $9.65 |
| EV Truck/SUV | 96.5 | 1 | $33.78 | $15.44 |
Gas CO2
84 kg
EV CO2
28 kg (67% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Late night in Natchez on Sunday
Local time
2:56 AM
CDT
Current temp
79°F
Unavailable
Destination
Late night in Starkville on Sunday
Local time
2:56 AM
CDT
Current temp
51°F
Unavailable
61°F
Pearl, MS
121 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Worth a detour if your schedule allows.
National Historical Park
Discover the history of all the peoples of Natchez, Mississippi, from European settlement, African enslavement, the American cotton economy, to the Civil Rights struggle on the lower Mississippi River...
National Monument
Medgar and Myrlie Evers were partners in the civil rights struggle. The assassination of Medgar Evers in the carport of their home on June 12, 1963, was the first murder of a nationally significant le...
Park data from the National Park Service API. Alerts update every 2 hours.
Expect a highway-focused experience for most of this 241.3-mile trip, as 93% of it is spent on faster roads like MS Hwy 25, I-55, and US 84. The longest uninterrupted stretch you'll encounter is 79.6 miles along MS Hwy 25, offering a good period of consistent driving. While the profile suggests a straightforward highway drive, the transition between these main arteries will offer some variety. You'll likely experience periods of steady cruising, characteristic of interstate travel, punctuated by the more direct routing of the US highways and state routes.
This is a straightforward highway drive that stays mostly on MS Hwy 25 and I 55. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 0.1 miles in near Franklin Street.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 15 significant decision points across 241.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (Franklin Street): Navigation decision point; at 112.4 miles (I 55): Highway fork - watch signs carefully; at 114.5 miles (I 55): Highway fork - watch signs carefully. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Natchez, MS and Starkville, MS, road signs point toward Grenada and Memphis.
Grenada
Memphis
Weekend Trip
Doable as a same-day drive at 4h 40m. Total distance: 241.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
4h 40m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (93%). Some complex stretches to watch for.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, EIA for fuel prices, and NPS for national parks. See our methodology for refresh cadence and limitations.
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