If you are planning a quick getaway from the coast to the interior of South Carolina, the 103.7-mile trip from Myrtle Beach to Dalzell is a straightforward option. Expect to spend about 2 hours and 19 minutes behind the wheel, making this a perfect candidate for a single-day journey. You will primarily navigate via East Myrtle Beach Highway, Highway 378, and Myrtle Beach Highway. With an estimated fuel cost of $17, it is an affordable transit between the Southeast coastal region and the inland areas. Because the duration is relatively short, you won't need to worry about booking an overnight stay unless your schedule requires one. This route offers a practical, no-nonsense connection for travelers looking to move efficiently between these two points.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Midpoint
51.8 miles from Myrtle Beach, SC
A natural place for your longest stop of the day
, about 1h 14m into the drive
.
Main Roads
Road
Distance
Duration
East Myrtle Beach Highway
36.1 mi
43m
Highway 378
22.9 mi
32m
Myrtle Beach Highway
13 mi
16m
US 501
10.5 mi
16m
Robert E Graham Freeway
5.9 mi
6m
Clarence Coker Highway
3.5 mi
4m
Thomas Sumter Highway
3.4 mi
3m
Camden Highway
2.2 mi
3m
Longest stretch:
East Myrtle Beach Highway
— 36.1 mi, about 43m
Turn-by-Turn Driving Directions
Step-by-step road directions between Myrtle Beach, SC and Dalzell, SC.
1
Start on this road
69 ft·9 sec·this road
2
Turn left
159 ft·13 sec
3
At end of road, turn right onto US 17 Business
0.1 mi·20 sec·North Kings Highway
4
Turn left onto 6th Avenue North
489 ft·21 sec·6th Avenue North
5
Continue on 6th Avenue North
0.2 mi·46 sec·6th Avenue North
6
At end of road, turn right onto Alder Street
154 ft·6 sec·Alder Street
7
Turn left onto US 501
11 mi·16 min·US 501
Use the straight / right lanes.
8
Continue on US 501
2.0 mi·3 min·Highway 501 East
9
Continue on US 501
1.5 mi·2 min·Church Street
10
Turn left onto US 378
1.1 mi·2 min·Wright Boulevard
11
Continue on US 378
23 mi·32 min·Highway 378
12
Continue on US 378
36 mi·43 min·East Myrtle Beach Highway
13
Continue on US 301; US 378
0.5 mi·1 min·Main Street
14
Turn slight right onto Clarence Coker Highway
3.5 mi·4 min·Clarence Coker Highway
15
Continue on US 378
13 mi·16 min·Myrtle Beach Highway
16
Keep slight right at fork onto US 378
5.9 mi·6 min·Robert E Graham Freeway
17
Take the exit
0.2 mi·25 sec
18
Turn slight right
117 ft·3 sec
19
Merge onto US 521
1.7 mi·2 min·Camden Highway
20
Continue on US 521
3.4 mi·3 min·Thomas Sumter Highway
21
Turn right onto Frierson Road
0.4 mi·34 sec·Frierson Road
22
At end of road, turn right onto Camden Highway
0.5 mi·1 min·Camden Highway
23
Arrive at destination
Camden Highway
Trip Plan
Because this is a 103.7-mile drive, you have plenty of flexibility regarding your departure time, though leaving early can help you avoid any unexpected traffic. Since there are no mandatory stops listed, you can easily complete the trip in one go, but keeping your own pace is simple given the manageable duration. Budgeting approximately $17 for fuel ensures you are covered for the entire trip, so fill up before you leave Myrtle Beach to keep things simple. Pay close attention to your speed as you transition between the highway stretches and the local sections of Highway 378. By staying mindful of these road changes, you can ensure a smooth, stress-free arrival in Dalzell.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
You may only need one short stretch break if traffic stays light.
The halfway point lands around 51.8 miles from Myrtle Beach, SC, or about 1h 14m into the drive.
The longest continuous stretch on this route runs about 36.1 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 23 miles or 36m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 51.8 miles or 1h 14m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 1h 56m
Traffic, exits, and arrival timing usually matter more near Dalzell, SC than in the middle of the route.
Before You Leave
+
Open the route before leaving Myrtle Beach, SC so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Myrtle Beach, SC
This is one driving day of about 103.7 miles and 2h 19m.
Your first comfortable stop window is around 23 miles from Myrtle Beach, SC.
This route can stay practical as a one-day drive if traffic stays reasonable.
The longest stretch is on East Myrtle Beach Highway for about 36.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 10
5 decision points cluster between mile 0 and 103.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
4
0 mi into trip|~0m in
Turn left
Navigation decision point
5
0 mi into trip|~0m in|US 17 Business / North Kings Highway
At end of road, turn right onto US 17 Business / North Kings Highway
Navigation decision point
4
0.2 mi into trip|~0m in|6th Avenue North
Turn left onto 6th Avenue North
Navigation decision point
5
0.4 mi into trip|~1m in|Alder Street
At end of road, turn right onto Alder Street
Navigation decision point
5
103.2 mi into trip|~2h 18m in|Camden Highway
At end of road, turn right onto Camden Highway
Navigation decision point
Fuel & Cost
Regular Gas
$16.22 one way
$32.43 round trip
$3.97/gal25.4 MPG avg36 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.34
$17.73
$35.46
premium
$4.70
$19.19
$38.39
diesel
$5.61
$22.90
$45.79
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$16
Meals
$25–$50
Total
$41–$66
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 36.3 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $11 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
31.1
0
$10.89
$4.98
Efficient EV
25.9
0
$9.07
$4.15
EV Truck/SUV
41.5
0
$14.52
$6.64
Gas CO2
36 kg
EV CO2
12 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 13, 2026
Origin
Myrtle Beach, SC
Late night
in Myrtle Beach on Sunday
Local time
4:00 AM
EDT
Current temp
63°F
Mostly Clear
SE 7 mph1% chanceLive forecast
Destination
Dalzell, SC
Late night
in Dalzell on Sunday
Local time
4:00 AM
EDT
Current temp
57°F
Mostly Clear
S 2 to 7 mph0% chanceLive forecast
74°F
Lake City, SC
52 mi in
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
6 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 19m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Congaree National Park
National Park
Astonishing biodiversity exists in Congaree National Park, the largest intact expanse of old growth bottomland hardwood forest remaining in the southeastern United States. Waters from the Congaree and...
24 mi from route
~59 min detour
Free
near mile 100.1
Caution: Backcountry Trail Conditions
Park Closure: Boardwalk Partially Closed for Construction
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive features a mixed profile that balances highway travel with local road navigation. You will find that only 40% of the journey is spent on highways, meaning you should be prepared for varying speed limits and road conditions. Your longest uninterrupted stretch occurs early on, covering 36.1 miles along the East Myrtle Beach Highway. As you progress, the road environment shifts, requiring you to remain alert as you transition between major thoroughfares and secondary routes. It is neither a pure interstate grind nor a strictly rural trek, providing a steady, functional driving experience from start to finish.
40% highway, the rest on surface roads — varied driving throughout.
23 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 36.1 mi on East Myrtle Beach Highway.
How Hard Is This Drive?
4/10
This route mixes highway mileage with some local-road sections near the start or finish. There are only a few real navigation decisions along the way. The trickiest moment comes early in the drive.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 2h 19m drive. You will face about 10 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: near the start: Navigation decision point; near the start (US 17 Business / North Kings Highway): Navigation decision point; at 0.2 miles (6th Avenue North): Navigation decision point.
Elevation Profile
Mostly flat terrain
217 ft24 ft
Total Climb
223 ft
Total Descent
30 ft
Highest Point
217 ft
~103.7 mi in
Elevation Range
194 ft
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 2h 19m. Total distance: 103.7 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Mixed highway & surface route profile with national parks nearby.
Frequently Asked Questions
The longest stretch is about 36.1 miles on East Myrtle Beach Highway. The full list of main roads is in the Roads section above.
Yes, with realistic expectations. Build in a stop roughly every 2 hours, have snacks and activities ready, and check the Nearby Places tabs for kid-friendly stops along the way.
The main spots that need attention: near the start: Navigation decision point; near the start (US 17 Business / North Kings Highway): Navigation decision point; at 0.2 miles (6th Avenue North): Navigation decision point.
Yes — Congaree National Park. See the National Parks section for detour distances and tips on detours.
Yes. A round trip is manageable in a single day if you plan a break at Dalzell, SC before heading back.
