This straightforward 124.2-mile drive from Mulberry to Port Saint Lucie takes about 2 hours and 33 minutes, making it a perfect day trip. You'll spend about 90% of your time on highways, with an estimated fuel cost of $20. The journey primarily follows FL 60 and Florida's Turnpike, offering a direct route across Florida. With just one recommended stop, this trip is designed for efficiency. It's a practical option for getting from one part of Florida to another with minimal fuss.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
62.1 miles from Mulberry, FL
A natural place for your longest stop of the day
, about 1h 21m into the drive
.
Main Roads
Road
Distance
Duration
FL 60
61.5 mi
1h 18m
Florida's Turnpike
49.8 mi
53m
Canal Street
6.7 mi
8m
Main Street
1.7 mi
3m
Southeast Airoso Boulevard
1.6 mi
2m
Southwest Port Saint Lucie Boulevard
0.8 mi
1m
Flamingo Drive
0.5 mi
<1m
South Church Avenue
0.1 mi
<1m
Longest stretch:
FL 60
— 61.5 mi, about 1h 18m
Turn-by-Turn Driving Directions
Step-by-step road directions between Mulberry, FL and Port Saint Lucie, FL.
1
Start on FL 37
199 ft·10 sec·South Church Avenue
2
Continue on FL 37
341 ft·16 sec·South Church Avenue
3
Turn left onto FL 60
6.7 mi·8 min·Canal Street
Use the left lane.
4
Continue on FL 60
0.7 mi·1 min·FL 60
Use the straight lane.
5
Turn right onto Main Street
1.7 mi·3 min·Main Street
Use the right lane.
6
Keep slight left at fork onto Flamingo Drive
0.5 mi·51 sec·Flamingo Drive
7
Turn right onto FL 60
10 mi·12 min·FL 60
Use the straight lane.
8
Continue on FL 60
4.3 mi·5 min·FL 60
Use the straight / slight right lanes.
9
Continue on FL 60
46 mi·59 min·FL 60
Use the left lane.
10
Take the exit
0.1 mi·19 sec
Use the left lane.
11
Continue on this road
295 ft·7 sec·this road
Use the straight / slight right lanes.
12
Keep slight right at fork
0.2 mi·22 sec
Toward Florida's Turnpike South: MiamiUse the straight / slight right lanes.
13
Merge onto Florida's Turnpike
50 mi·53 min·Florida's Turnpike
14
Take the exit
1.0 mi·2 min
Exit 142Toward Port Saint Lucie
15
Continue on Southwest Bayshore Boulevard
483 ft·15 sec·Southwest Bayshore Boulevard
16
Turn right onto FL 716
0.8 mi·1 min·Southwest Port Saint Lucie Boulevard
Use the right lane.
17
Turn left onto CR 615
1.6 mi·2 min·Southeast Airoso Boulevard
Use the left / uturn lanes.
18
Turn left onto Southwest Carter Avenue
215 ft·9 sec·Southwest Carter Avenue
19
Arrive at destination
Southwest Carter Avenue
Trip Plan
Given the 2-hour 33-minute duration, leaving Mulberry in the morning will comfortably get you to Port Saint Lucie by midday. The estimated fuel cost of $20 is quite reasonable for this 124.2-mile trip, so plan to fill up before you leave or at one of the many service areas along Florida's Turnpike. The longest stretch without a major exit is 61.5 miles on FL 60, so ensure you have snacks and drinks if needed before embarking on that segment. This route is well-suited for a single day, offering flexibility in your departure time.
Morning Departure
Leave by 9 AM and you'll arrive before lunch.
Evening Departure
Even a 4 PM departure gets you there before dark in summer.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 62.1 miles from Mulberry, FL, or about 1h 21m into the drive.
The longest continuous stretch on this route runs about 61.5 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 27 miles or 36m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 62.1 miles or 1h 21m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 2h 5m
Traffic, exits, and arrival timing usually matter more near Port Saint Lucie, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Mulberry, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Mulberry, FL
This is one driving day of about 124.2 miles and 2h 33m.
Your first comfortable stop window is around 27 miles from Mulberry, FL.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on FL 60 for about 61.5 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 12
5 decision points cluster between mile 7.5 and 122.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
6
7.5 mi into trip|~10m in|Main Street
Turn right onto Main Street
Lane positioning matters here
Use the right lane.
6
70.4 mi into trip|~1h 31m in
Take the exit
Exit ramp - move to the correct lane early. Lane positioning matters here
Use the left lane.
8
70.7 mi into trip|~1h 32m in
Keep slight right at fork toward Florida's Turnpike South: Miami
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight / slight right lanes.
Toward Florida's Turnpike South: Miami
6
121.8 mi into trip|~2h 28m in|FL 716 / Southwest Port Saint Lucie Boulevard
Turn right onto FL 716 / Southwest Port Saint Lucie Boulevard
Lane positioning matters here
Use the right lane.
6
122.6 mi into trip|~2h 30m in|CR 615 / Southeast Airoso Boulevard
Turn left onto CR 615 / Southeast Airoso Boulevard
Lane positioning matters here
Use the left / uturn lanes.
Fuel & Cost
Regular Gas
$19.77 one way
$39.54 round trip
$4.04/gal25.4 MPG avg44 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.40
$21.51
$43.01
premium
$4.72
$23.09
$46.19
diesel
$5.61
$27.42
$54.84
Estimated Tolls: $3.49
Florida's Turnpike
(49.8 mi)$3.49
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$20
Tolls
$3
Meals
$25–$50
Total
$48–$73
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 43.5 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $13 in charging
· 0 stops
· 65% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
37.3
0
$13.04
$5.96
Efficient EV
31.1
0
$10.87
$4.97
EV Truck/SUV
49.7
0
$17.39
$7.95
Gas CO2
43 kg
EV CO2
15 kg (65% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 20, 2026
Origin
Mulberry, FL
Late night
in Mulberry on Tuesday
Local time
5:17 AM
EDT
Current temp
65°F
Unavailable
Live forecast
Destination
Port Saint Lucie, FL
Late night
in Port Saint Lucie on Tuesday
Local time
5:17 AM
EDT
Current temp
87°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
22 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
2h 33m on the road
Use the two city cards together: check the sky where you start, then compare it with the local time and temperature at arrival.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
Expect a highway-focused experience on this route, with 90% of the drive on faster roads. You'll encounter a significant uninterrupted stretch of 61.5 miles on FL 60, so be prepared for longer periods without exits. The route transitions from FL 60 to Florida's Turnpike, indicating a shift in road type and potentially speed. Canal Street is also part of the main roads, suggesting a more localized section as you approach your destination. This drive is about covering ground efficiently rather than winding scenic byways.
90% highway — fuel and pacing are the main things to plan.
19 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 61.5 mi on FL 60.
How Hard Is This Drive?
6/10
This is a straightforward highway drive that stays mostly on FL 60 and Florida's Turnpike. You will hit about 12 points where you need to pay attention to lane position or signs. The trickiest moment comes around 7.5 miles in near Main Street.
Driving Effort6/10
Moderate - straightforward overall, but long enough or busy enough to require pacing
Balances navigation complexity with total wheel time.
This drive requires moderate attention. Across 124.2 miles you will encounter 12 spots where lane choice or exit timing matters. Not difficult for experienced highway drivers, but worth previewing the tricky sections before you go.
Where does it get tricky?
The main spots that need attention: at 7.5 miles (Main Street): Lane positioning matters here; at 70.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 70.7 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Mulberry, FL to Port Saint Lucie, FL, road signs begin pointing toward Florida's Turnpike South: Miami along the way.
Doable as a same-day drive at 2h 33m. Total distance: 124.2 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
2h 33m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (90%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 61.5 miles on FL 60. The full list of main roads is in the Roads section above.
Expect about $3.49 in tolls one way, starting with Florida's Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Port Saint Lucie, FL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 7.5 miles (Main Street): Lane positioning matters here; at 70.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here; at 70.7 miles: Highway fork - watch signs carefully. Lane positioning matters here.
Yes. A round trip is manageable in a single day if you plan a break at Port Saint Lucie, FL before heading back.
