Spanning 470.5 miles across the state of Florida, this trip from Port Saint Lucie to Callaway takes approximately 8 hours and 49 minutes of pure driving time. Because of the length, you should plan for a two-day itinerary to keep the journey manageable and stress-free. You will primarily utilize a mix of Florida's Turnpike, I-75, and I-10 to make your way north and west. Budget roughly $79 for fuel to cover the distance between these two coastal regions. While it is technically possible to push through in one long day, splitting the drive into two days allows you to navigate the major interstates without feeling exhausted upon arrival.
Trip Pace
Best split across 2 days
Treat the return leg as its own travel day rather than an afterthought.
Break Rhythm
2 planned breaks
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
235.3 miles from Port Saint Lucie, FL
A natural place for your longest stop of the day
, about 4h 15m into the drive
.
Main Roads
Road
Distance
Duration
Florida's Turnpike
165.1 mi
2h 56m
I 10
121.8 mi
2h 10m
I 75
106.9 mi
1h 54m
FL 20
28.4 mi
39m
Bristol Highway
17.7 mi
23m
US 231
16.1 mi
20m
Star Avenue
6.7 mi
10m
Greensboro Highway
2.4 mi
3m
Longest stretch:
Florida's Turnpike
— 165.1 mi, about 2h 56m
Turn-by-Turn Driving Directions
Step-by-step road directions between Port Saint Lucie, FL and Callaway, FL.
1
Start on Southwest Carter Avenue
215 ft·11 sec·Southwest Carter Avenue
2
Turn right onto CR 615
1.6 mi·2 min·Southeast Airoso Boulevard
3
Turn right onto FL 716
0.8 mi·1 min·Southwest Port Saint Lucie Boulevard
4
Turn left onto Southwest Bayshore Boulevard
0.1 mi·21 sec·Southwest Bayshore Boulevard
5
Take the ramp
0.5 mi·1 min
Toward Florida's Turnpike Toll
6
Keep slight right at fork
0.3 mi·45 sec
Toward Orlando, Florida's Turnpike NorthUse the slight right lane.
7
Merge onto Florida's Turnpike
165 mi·2 hr 56 min·Florida's Turnpike
Use the straight lane.
8
Keep slight left at fork onto Florida's Turnpike
0.2 mi·15 sec·Florida's Turnpike
Toward I 75 North: OcalaUse the straight lane.
9
Merge onto I 75
107 mi·1 hr 54 min·I 75
Use the straight / slight right lanes.
10
Take the exit
0.2 mi·15 sec
Exit 435Toward I 10: Jacksonville, TallahasseeUse the straight / slight right lanes.
11
Keep slight left at fork
0.3 mi·30 sec
Toward I 10 West: TallahasseeUse the slight left / slight right lanes.
12
Merge onto I 10
122 mi·2 hr 10 min·I 10
Use the straight / slight right lanes.
13
Take the exit
0.3 mi·45 sec
Exit 174Toward FL 12: Gretna, GreensboroUse the straight / slight right lanes.
14
Keep slight left at fork
366 ft·11 sec
Toward FL `12 South: Greensboro
15
Turn straight onto FL 12
2.4 mi·3 min·Greensboro Highway
16
Continue on FL 12
0.6 mi·1 min·Selman Street
17
Turn left onto FL 12
0.4 mi·57 sec·Green Avenue
18
Continue on FL 12
18 mi·23 min·Bristol Highway
19
At end of road, turn right onto FL 20
28 mi·39 min·FL 20
20
Turn left onto US 231
16 mi·20 min·US 231
21
Turn left onto CR 2293; CR 2315
6.7 mi·10 min·Star Avenue
22
Turn right onto FL 22
0.2 mi·24 sec·Wewa Highway
23
Arrive at destination
FL 22
Trip Plan
To make the most of this 470.5-mile journey, try to depart early in the morning to beat the peak congestion often found on major Florida arteries. Since the route requires two stops, plan your breaks strategically along the interstate to keep your energy levels consistent over the two-day drive. Keep a close eye on your fuel gauge during that 165.1-mile Turnpike stretch, as service plazas can become spaced out. By pacing yourself and utilizing the two recommended stops, you ensure that you reach Callaway feeling refreshed rather than drained. Prioritize safety on these high-speed corridors by staying alert to the heavy volume of through-traffic common on I-10 and I-75.
Morning Departure
Start early — leave by 6-7 AM to arrive at a reasonable hour.
Evening Departure
This is a long drive — plan for a morning departure or consider splitting it into two days.
This drive is better paced as a 2-day trip.
Plan roughly 2 meaningful breaks for fuel, food, and rest.
The halfway point lands around 235.3 miles from Port Saint Lucie, FL, or about 4h 15m into the drive.
The longest continuous stretch on this route runs about 165.1 miles.
Consider an overnight stop or starting very early.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 104 miles or 1h 54m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 235.3 miles or 4h 15m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Overnight split
Day 1 wrap after about 235.3 miles or 4h 15m
Stop before fatigue turns the last few hours into a grind. You want day two to start fresh, not just resumed.
Final approach
Final hour starts around 7h 28m
Traffic, exits, and arrival timing usually matter more near Callaway, FL than in the middle of the route.
Before You Leave
+
Open the route before leaving Port Saint Lucie, FL so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
+
Pick one backup stop option before the midpoint in case traffic changes your pacing.
+
Treat this as a 2-day road trip and book the overnight stop before the busiest arrival window.
Day 1
Settle into the route from Port Saint Lucie, FL
Aim for roughly 235 miles and 4.4 hours of wheel time on this day.
Day 2
Finish the approach into Callaway, FL
Aim for roughly 235 miles and 4.4 hours of wheel time on this day.
Your first comfortable stop window is around 104 miles from Port Saint Lucie, FL.
This route usually feels better as a 2-day drive than as one long push.
Plan about 2 real breaks rather than only quick fuel stops.
The longest stretch is on Florida's Turnpike for about 165.1 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
4.9 mi from route
~12 min detour
$1 to $10
mile 369.7
Tallahassee, Florida
Hours: 11 am–4 pm
+18505659955
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 16
5 decision points cluster between mile 3.1 and 397.7 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
8
3.1 mi into trip|~5m in
Keep slight right at fork toward Orlando, Florida's Turnpike North
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward Orlando, Florida's Turnpike North
7
168.2 mi into trip|~3h 3m in|Florida's Turnpike
Keep slight left at fork onto Florida's Turnpike toward I 75 North: Ocala
Highway fork - watch signs carefully. Lane positioning matters here
Use the straight lane.
Toward I 75 North: Ocala
8
275.4 mi into trip|~4h 58m in
Take the exit toward I 10: Jacksonville, Tallahassee
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 435
Toward I 10: Jacksonville, Tallahassee
8
275.6 mi into trip|~4h 58m in
Keep slight left at fork toward I 10 West: Tallahassee
Highway fork - watch signs carefully. Lane positioning matters here
Use the slight left / slight right lanes.
Toward I 10 West: Tallahassee
8
397.7 mi into trip|~7h 9m in
Take the exit toward FL 12: Gretna, Greensboro
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the straight / slight right lanes.
Exit 174
Toward FL 12: Gretna, Greensboro
Fuel & Cost
Regular Gas
$74.89 one way
$149.78 round trip
$4.04/gal25.4 MPG avg165 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.40
$81.47
$162.93
premium
$4.72
$87.49
$174.97
diesel
$5.61
$103.88
$207.76
Estimated Tolls: $11.54
Florida's Turnpike
(164.8 mi)$11.54
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$75
Tolls
$12
Hotel (1n)
$80–$140
Meals
$50–$100
Total
$216–$326
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 164.6 kg one way.
Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $49 in charging
· 1 stop
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
141.2
1
$49.40
$22.58
Efficient EV
117.6
1
$41.17
$18.82
EV Truck/SUV
188.2
2
$65.87
$30.11
Gas CO2
165 kg
EV CO2
55 kg (67% less)
Plan for 1 charging stop. A 30-minute DC fast charge mid-route should be enough to complete the trip comfortably.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Apr 15, 2026
Origin
Port Saint Lucie, FL
Night
in Port Saint Lucie on Saturday
Local time
10:54 PM
EDT
Current temp
64°F
Unavailable
Live forecast
Destination
Callaway, FL
Night
in Callaway on Saturday
Local time
9:54 PM
CDT
Current temp
63°F
Unavailable
Live forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
For long drives, weather on day two can matter just as much as conditions at departure, so check the whole travel window rather than only the first day.
Time zone
1 hour earlier
The destination clock does not match departure time, so double-check hotel check-in windows and late arrival plans.
Temperature spread
1 degrees cooler at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
8h 49m on the road
This is long enough that the arrival forecast matters almost as much as departure conditions. Recheck both ends before you roll.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This route is a quintessential highway-focused drive, with 93% of your journey spent on high-speed roads. Expect a consistent interstate experience, beginning with a significant 165.1-mile stretch on Florida's Turnpike that serves as the longest uninterrupted segment of your trip. As you transition onto I-75 and then I-10, you will find that the rhythm of the drive stays steady and fast-paced. It is not a technical or winding route, but rather a straightforward, efficient path that prioritizes speed over local scenery. You should prepare for a professional, highway-centric environment that keeps your momentum high from start to finish.
93% highway — fuel and pacing are the main things to plan.
23 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 165.1 mi on Florida's Turnpike.
How Hard Is This Drive?
8/10
This is a straightforward highway drive that stays mostly on Florida's Turnpike and I 10. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 3.1 miles in.
Driving Effort8/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 16 significant decision points across 470.5 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 3.1 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 168.2 miles (Florida's Turnpike): Highway fork - watch signs carefully. Lane positioning matters here; at 275.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Mostly flat terrain
258 ft17 ft
Total Climb
380 ft
Total Descent
364 ft
Highest Point
258 ft
~403.3 mi in
Elevation Range
242 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Port Saint Lucie, FL and Callaway, FL, road signs point toward Tallahassee, Greensboro and Fl `12 South: Greensboro.
Tallahassee
275.4 mi in|~4h 58m
Greensboro
397.7 mi in|~7h 9m
Fl `12 South: Greensboro
398 mi in|~7h 10m
Frequently Asked Questions
The longest stretch is about 165.1 miles on Florida's Turnpike. The full list of main roads is in the Roads section above.
Yes — a 2-day pace is more comfortable than one long haul. A sensible stopping point is after roughly 235 miles on day one.
Expect about $11.54 in tolls one way, starting with Florida's Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Callaway, FL before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 2 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 3.1 miles: Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one; at 168.2 miles (Florida's Turnpike): Highway fork - watch signs carefully. Lane positioning matters here; at 275.4 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Not recommended in a single day. At 8.8 hours each way, a round trip means 17.7 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Callaway, FL before the return drive.
