Mount Pleasant to Saint Elizabeth is 31.3 miles and takes about 47 minutes via MO 52 and US 54, with a fuel budget near $5 and enough daylight to finish in a day. This short Midwest drive connects two points within Missouri, offering a straightforward trip. You'll spend nearly all your time on highways, making for a quick transit. If you're looking for a simple, direct connection between these two locations, this route fits the bill without much fuss.
Main Roads
Road
Distance
Duration
MO 52
12.9 mi
22m
US 54 Bus
9.7 mi
14m
US 54
7.4 mi
8m
MO 17
0.9 mi
1m
MO FF
<0.1 mi
<1m
Doyle Road
<0.1 mi
<1m
County Road 54-66
<0.1 mi
<1m
Walnut Street
—
—
Some road-level metrics are being recalculated.
Longest stretch:
MO 52
— 12.9 mi, about 22m
Turn-by-Turn Driving Directions
Step-by-step road directions between Mount Pleasant, MO and Saint Elizabeth, MO.
1
Start on Doyle Road
267 ft·17 sec·Doyle Road
2
Turn left onto MO FF
387 ft·14 sec·MO FF
3
Turn right onto US 54
1.0 mi·1 min·US 54
4
Turn left onto County Road 54-66
169 ft·12 sec·County Road 54-66
5
Turn left onto US 54
6.5 mi·6 min·US 54
6
Take the exit
0.2 mi·22 sec
Toward US 54 Business, MO 52: Tuscumbia, Eldon
7
Turn left onto US 54 Bus; MO 52
9.7 mi·14 min·US 54 Bus; MO 52
8
Turn right onto MO 17; MO 52
0.9 mi·1 min·MO 17; MO 52
9
Turn left onto MO 52
13 mi·22 min·MO 52
10
Arrive at destination
MO 52
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
The midpoint is around 15.6 miles from Mount Pleasant, MO, which is a good place for a longer meal and fuel stop.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
Heads-up: tricky spots
5 of 8
5 decision points cluster between mile 0.1 and 7.6 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
5
0.1 mi into trip|~0m in|MO FF
Turn left onto MO FF
Navigation decision point
4
0.1 mi into trip|~0m in|US 54
Turn right onto US 54
Navigation decision point
4
1.1 mi into trip|~1m in|County Road 54-66
Turn left onto County Road 54-66
Navigation decision point
4
1.1 mi into trip|~1m in|US 54
Turn left onto US 54
Navigation decision point
5
7.6 mi into trip|~8m in
Take the exit toward US 54 Business, MO 52: Tuscumbia, Eldon
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Toward US 54 Business, MO 52: Tuscumbia, Eldon
Fuel & Cost
Regular Gas
$4.65 one way
$9.29 round trip
$3.77/gal25.4 MPG avg11 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.25
$5.24
$10.48
premium
$4.65
$5.74
$11.47
diesel
$5.30
$6.54
$13.07
No toll roads detected on this route.
Drive Cost (one way)
Fuel
$5
Estimated CO2 emission: 11 kg one way.
Driving Electric?
About $3 in charging
· 0 stops
· 64% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
9.4
0
$3.29
$1.50
Efficient EV
7.8
0
$2.74
$1.25
EV Truck/SUV
12.5
0
$4.38
$2.00
Gas CO2
11 kg
EV CO2
4 kg (64% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Jun 27, 2026
Origin
Mount Pleasant, MO
Evening
in Mount Pleasant on Monday
Local time
7:09 PM
CDT
Current temp
87°F
Chance Showers And Thunderstorms
SW 5 mph37% chanceLive forecast
Heat Advisory
Heat Advisory issued June 27 at 1:17PM CDT until July 2 at 8:00PM CDT by NWS Springfield MO
Heat Advisory
Heat Advisory issued June 27 at 1:15PM CDT until July 3 at 12:00AM CDT by NWS St Louis MO
Destination
Saint Elizabeth, MO
Evening
in Saint Elizabeth on Monday
Local time
7:09 PM
CDT
Current temp
88°F
Chance Showers And Thunderstorms
SW 5 mph38% chanceLive forecast
Heat Advisory
Heat Advisory issued June 27 at 1:17PM CDT until July 2 at 8:00PM CDT by NWS Springfield MO
Heat Advisory
Heat Advisory issued June 27 at 1:15PM CDT until July 3 at 12:00AM CDT by NWS St Louis MO
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
1 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
47m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
More Details
What kind of drive is this?
This route is almost entirely highway driving, with a 99% highway share. You'll be on MO 52 for the longest continuous stretch, covering 12.9 miles. The transition from MO 52 to US 54 will feel like a natural progression of highway cruising. Expect minimal surface road time, making it a very efficient drive.
99% highway — fuel and pacing are the main things to plan.
10 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 12.9 mi on MO 52.
How Hard Is This Drive?
4/10
This is a straightforward highway drive that stays mostly on MO 52 and US 54 Bus. There are only a few real navigation decisions along the way. The trickiest moment comes around 0.1 miles in near MO FF.
Driving Effort4/10
Easy - simple navigation with a manageable amount of wheel time
Balances navigation complexity with total wheel time.
This is a straightforward 47m drive. You will face about 8 decision points, but nothing that requires special attention if you follow navigation.
Where does it get tricky?
The main spots that need attention: at 0.1 miles (MO FF): Navigation decision point; at 0.1 miles (US 54): Navigation decision point; at 1.1 miles (County Road 54-66): Navigation decision point.
Elevation Profile
Mostly flat terrain
925 ft542 ft
Total Climb
676 ft
Total Descent
782 ft
Highest Point
925 ft
~8.9 mi in
Elevation Range
383 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Mount Pleasant, MO to Saint Elizabeth, MO, road signs begin pointing toward Eldon along the way.
Eldon
7.6 mi in|~8m
Who Is This Route For?
Weekend Trip
Doable as a same-day drive at 47m. Total distance: 31.3 miles.
Family Friendly
Moderate complexity with 0 natural rest stops along the way.
Solo Traveler
47m drive, comfortable solo distance.
EV Driver
0 DC fast chargers along the route. Coverage: unknown.
The longest stretch is about 12.9 miles on MO 52. The full list of main roads is in the Roads section above.
Yes. At under 2 hours behind the wheel, this works well for families — plan one quick stop if you have younger kids.
The main spots that need attention: at 0.1 miles (MO FF): Navigation decision point; at 0.1 miles (US 54): Navigation decision point; at 1.1 miles (County Road 54-66): Navigation decision point.
Yes. A round trip is manageable in a single day if you plan a break at Saint Elizabeth, MO before heading back.
