Origin
Middleburg, PA
Morning in Middleburg on Sunday
Local time
6:31 AM
EDT
Current temp
40°F
Unavailable
Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards
Drive Time
5h 18m
Distance
261.4 mi
421 km
Drive Score
8/10
Great drive
Same Day?
Yes, doable
Fuel Cost
$43
one way
EV Charging
Unknown
Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.
Middleburg, PA
Michael Taccetta
Pittsburgh, PA
Wikimedia Commons
This 261.4-mile journey from Middleburg, PA, to Pittsburgh, PA, is a solid day trip, estimated to take about 5 hours and 18 minutes of driving. You'll be navigating a mix of roads, including the Keystone Shortway and I-99, with about 18% of your travel on highways. The estimated fuel cost for this trip is around $43, and with only one recommended stop, it's a fairly direct drive. The route's turn-heavy local character suggests you'll be experiencing varied driving conditions rather than a monotonous interstate cruise. This drive is entirely within Pennsylvania, so you won't be crossing regional boundaries, but expect a shift in scenery as you head west.
Trip Pace
Same-day drive is realistic
A same-day return is possible, but it will make for a full day on the road.
Break Rhythm
1 planned break
Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.
Midpoint
130.7 miles from Middleburg, PA
A natural place for your longest stop of the day , about 2h 26m into the drive .
| Road | Distance | Duration |
|---|---|---|
| Keystone Shortway | 111.5 mi | 2h 2m |
| William Penn Highway | 61.2 mi | 1h 25m |
| I 99 | 33.8 mi | 36m |
| Jacksonville Road | 24.2 mi | 28m |
| Penn-Lincoln Parkway East | 13.5 mi | 18m |
| Admiral Peary Highway | 13.4 mi | 19m |
| Towanda Street | 0.3 mi | <1m |
| Chestnut Street | 0.3 mi | <1m |
Step-by-step road directions between Middleburg, PA and Pittsburgh, PA.
Start on Chestnut Street
Continue on Towanda Street
Turn right onto PA 940
Turn left onto PA 940
Take the ramp
Merge onto I 80
Take the exit
Turn left onto US 220; PA 26
Keep slight left at fork onto I 99; US 220
Take the exit
Continue on this road
Continue on US 22
Continue on US 22
Continue on US 22
Keep slight right at fork onto I 376; US 22
Take the exit
Turn straight onto Second Avenue
At end of road, turn right onto Ross Street
Turn left onto Fifth Avenue
Turn right onto Grant Street
Arrive at destination
With a driving duration of 5 hours and 18 minutes, this 261.4-mile trip is comfortably manageable as a single-day adventure. Aim to depart from Middleburg, PA, in the morning to maximize daylight and allow for flexibility. While only one stop is officially recommended, keep an eye on your fuel gauge, especially considering the $43 estimated cost. The longest stretch without significant interruption is 111.5 miles on the Keystone Shortway, so plan your break before or after this segment to ensure you stay refreshed. This route's 'turn-heavy local drive' profile means paying close attention to navigation and speed limits.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 58 miles or 1h 5m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 130.7 miles or 2h 26m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 4h 9m
Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.
Open the route before leaving Middleburg, PA so your first major turns are already loaded.
Leave with enough water and a charging cable within reach, not packed away.
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Middleburg, PA
This is one driving day of about 261.4 miles and 5h 18m.
Rest stops, refuel points, and overnight suggestions along this route.
Mid-route town
Meal stop
131 mi into the route
Best for: Lunch, fuel, and a longer reset
This sits close to the middle of the route, so it works well for the longest stop of the day.
A short stop after about 58 miles helps settle the day before fatigue starts building.
The midpoint is around 130.7 miles from Middleburg, PA, which is a good place for a longer meal and fuel stop.
Before the longest stretch
Fuel checkTop up before Keystone Shortway if your tank is already low. That segment runs about 111.5 miles.
These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.
5 decision points cluster between mile 112.8 and 261.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
Take the exit toward I 99 South, US 220 South, PA 26: Bellefonte
Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one
Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona
Highway fork - watch signs carefully. Multiple destination signs - pick the right one
Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh
Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one
Take the exit toward Second Avenue
Exit ramp - move to the correct lane early. Lane positioning matters here
Turn right onto Grant Street
Lane positioning matters here
Regular Gas
$43.34 one way
$86.67 round trip
| Fuel Type | $/gal | One Way | Round Trip |
|---|---|---|---|
| midgrade | $4.61 | $47.46 | $94.93 |
| premium | $4.93 | $50.70 | $101.39 |
| diesel | $5.61 | $57.71 | $115.43 |
No toll roads detected on this route.
Estimated Trip Cost (one way, 1 person)
Fuel
$43
Meals
$25–$50
Total
$68–$93
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 91.5 kg one way. Prices: EIA weekly data, 2026-04-13.
Driving Electric?
About $27 in charging · 0 stops · 66% less CO2
| Vehicle Type | kWh | Stops | DC Fast | Home Charge |
|---|---|---|---|---|
| Average EV | 78.4 | 0 | $27.45 | $12.55 |
| Efficient EV | 65.4 | 0 | $22.87 | $10.46 |
| EV Truck/SUV | 104.6 | 1 | $36.60 | $16.73 |
Gas CO2
91 kg
EV CO2
31 kg (66% less)
Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Current conditions at both ends of the drive.
Origin
Morning in Middleburg on Sunday
Local time
6:31 AM
EDT
Current temp
40°F
Unavailable
Destination
Morning in Pittsburgh on Sunday
Local time
6:31 AM
EDT
Current temp
85°F
Chance Showers And Thunderstorms
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
An early start around 7-8 AM gets you there with plenty of daylight left.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
Expect a 'turn-heavy local drive' profile for this 261.4-mile route. While 18% of your journey will be on highways, much of the 5-hour and 18-minute drive will involve navigating local roads and the Keystone Shortway. The longest uninterrupted stretch you'll encounter is 111.5 miles on the Keystone Shortway, offering a good period of consistent travel before more varied conditions return. This mix means you'll likely experience frequent changes in speed and road type, keeping you engaged behind the wheel.
Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 112.8 miles in.
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 13 significant decision points across 261.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 112.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 137.3 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 247.1 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
Between Middleburg, PA and Pittsburgh, PA, road signs point toward Altoona and Hollidaysburg.
Altoona
Hollidaysburg
The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.
City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).
Weekend Trip
Doable as a same-day drive at 5h 18m. Total distance: 261.4 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
5h 18m drive, comfortable solo distance.
Scenic Drive
Mostly surface roads route profile.
Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.
Was this helpful?
Thanks for your feedback!
Your tip has been submitted. Thanks!
/500
Recent Tips
·
Explore more options from Middleburg, PA or browse trips ending in Pittsburgh, PA.
Looking for more statewide routes? Browse PA road trips.