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Trip from Middleburg, PA to Pittsburgh, PA

Compiled and reviewed by the US Trip Planner planning team at COD Solutions Oy · Last reviewed Apr 19, 2026 · Editorial standards

Drive Time

5h 18m

Distance

261.4 mi

421 km

Drive Score

8/10

Great drive

Same Day?

Yes, doable

Fuel Cost

$43

one way

EV Charging

Unknown

Best Time to Leave

Save up to 40 min
4 AM
5h 6m ★
6 AM
5h 19m
8 AM
5h 46m
10 AM
5h 28m
12 PM
5h 26m
3 PM
5h 30m
5 PM
5h 45m
8 PM
5h 11m

Estimated drive times based on typical traffic patterns. Actual times may vary with weather, construction, and real-time conditions.

Downtown Middleburg, PA, PA

Middleburg, PA

Michael Taccetta

city and county seat in Allegheny County, Pennsylvania, United States

Pittsburgh, PA

Wikimedia Commons

Trip Overview

This 261.4-mile journey from Middleburg, PA, to Pittsburgh, PA, is a solid day trip, estimated to take about 5 hours and 18 minutes of driving. You'll be navigating a mix of roads, including the Keystone Shortway and I-99, with about 18% of your travel on highways. The estimated fuel cost for this trip is around $43, and with only one recommended stop, it's a fairly direct drive. The route's turn-heavy local character suggests you'll be experiencing varied driving conditions rather than a monotonous interstate cruise. This drive is entirely within Pennsylvania, so you won't be crossing regional boundaries, but expect a shift in scenery as you head west.

Trip Pace

Same-day drive is realistic

A same-day return is possible, but it will make for a full day on the road.

Break Rhythm

1 planned break

Plan on a short reset every 3 to 4 hours to stay fresh behind the wheel.

Midpoint

130.7 miles from Middleburg, PA

A natural place for your longest stop of the day , about 2h 26m into the drive .

Main Roads

Road Distance Duration
Keystone Shortway 111.5 mi 2h 2m
William Penn Highway 61.2 mi 1h 25m
I 99 33.8 mi 36m
Jacksonville Road 24.2 mi 28m
Penn-Lincoln Parkway East 13.5 mi 18m
Admiral Peary Highway 13.4 mi 19m
Towanda Street 0.3 mi <1m
Chestnut Street 0.3 mi <1m
Longest stretch: Keystone Shortway — 111.5 mi, about 2h 2m

Turn-by-Turn Driving Directions

Step-by-step road directions between Middleburg, PA and Pittsburgh, PA.

1

Start on Chestnut Street

0.3 mi · 45 sec · Chestnut Street
2

Continue on Towanda Street

0.3 mi · 49 sec · Towanda Street
3

Turn right onto PA 940

0.2 mi · 23 sec · Berwick Street
4

Turn left onto PA 940

0.3 mi · 28 sec · Church Street
5

Take the ramp

0.2 mi · 28 sec
6

Merge onto I 80

111 mi · 2 hr 2 min · Keystone Shortway
7

Take the exit

0.3 mi · 53 sec
Exit 161 Toward I 99 South, US 220 South, PA 26: Bellefonte
8

Turn left onto US 220; PA 26

24 mi · 28 min · Jacksonville Road
Use the straight lane.
9

Keep slight left at fork onto I 99; US 220

34 mi · 36 min · I 99; US 220
Toward I 99 South, US 220 South: Port Matilda, Altoona
10

Take the exit

0.8 mi · 1 min
Toward US 22: Ebensburg, Hollidaysburg
11

Continue on this road

0.5 mi · 43 sec · this road
12

Continue on US 22

16 mi · 19 min · William Penn Highway
13

Continue on US 22

13 mi · 19 min · Admiral Peary Highway
Use the straight lane.
14

Continue on US 22

45 mi · 1 hr 6 min · William Penn Highway
Use the straight / right lanes.
15

Keep slight right at fork onto I 376; US 22

13 mi · 18 min · Penn-Lincoln Parkway East
Toward I 376 West, US 22 West: Pittsburgh Use the slight left lane.
16

Take the exit

0.2 mi · 38 sec
Exit 71B Toward Second Avenue Use the straight / slight right lanes.
17

Turn straight onto Second Avenue

0.3 mi · 41 sec · Second Avenue
18

At end of road, turn right onto Ross Street

0.2 mi · 32 sec · Ross Street
19

Turn left onto Fifth Avenue

352 ft · 10 sec · Fifth Avenue
20

Turn right onto Grant Street

513 ft · 21 sec · Grant Street
Use the right lane.
21

Arrive at destination

Grant Street

Trip Plan

With a driving duration of 5 hours and 18 minutes, this 261.4-mile trip is comfortably manageable as a single-day adventure. Aim to depart from Middleburg, PA, in the morning to maximize daylight and allow for flexibility. While only one stop is officially recommended, keep an eye on your fuel gauge, especially considering the $43 estimated cost. The longest stretch without significant interruption is 111.5 miles on the Keystone Shortway, so plan your break before or after this segment to ensure you stay refreshed. This route's 'turn-heavy local drive' profile means paying close attention to navigation and speed limits.

Morning Departure

An early start around 7-8 AM gets you there with plenty of daylight left.

Evening Departure

A late afternoon start means arriving after dark. Morning is better.

You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 130.7 miles from Middleburg, PA, or about 2h 26m into the drive.
The longest continuous stretch on this route runs about 111.5 miles.

This is a comfortable same-day trip.

Departure

Before you leave

Start with fuel, water, and navigation already sorted so the first hour feels easy.

First stop

Around 58 miles or 1h 5m in

Use this first pause for coffee, a restroom break, and a quick traffic check ahead.

Halfway reset

Around 130.7 miles or 2h 26m in

This is the best place for your longest stop, a real meal, and a full fuel check.

Final approach

Final hour starts around 4h 9m

Traffic, exits, and arrival timing usually matter more near Pittsburgh, PA than in the middle of the route.

Before You Leave

+

Open the route before leaving Middleburg, PA so your first major turns are already loaded.

+

Leave with enough water and a charging cable within reach, not packed away.

+

Check your fuel range against the first long segment, especially if you are starting outside city service areas.

Day 1

Settle into the route from Middleburg, PA

This is one driving day of about 261.4 miles and 5h 18m.

Your first comfortable stop window is around 58 miles from Middleburg, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Keystone Shortway for about 111.5 miles.

Where to Stop

Rest stops, refuel points, and overnight suggestions along this route.

Mid-route town

Meal stop

Altoona, PA

131 mi into the route

Best for: Lunch, fuel, and a longer reset

This sits close to the middle of the route, so it works well for the longest stop of the day.

Pacing Suggestions

Catawissa, PA

Fuel and coffee

A short stop after about 58 miles helps settle the day before fatigue starts building.

State College, PA

Meal break

The midpoint is around 130.7 miles from Middleburg, PA, which is a good place for a longer meal and fuel stop.

Before the longest stretch

Fuel check

Top up before Keystone Shortway if your tank is already low. That segment runs about 111.5 miles.

These stop ideas are pacing suggestions — the exact town or exit can change with traffic, hotel plans, and fuel range.

Heads-up: tricky spots

5 of 13

5 decision points cluster between mile 112.8 and 261.3 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.

6
112.8 mi into trip | ~2h 5m in

Take the exit toward I 99 South, US 220 South, PA 26: Bellefonte

Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one

Exit 161 Toward I 99 South, US 220 South, PA 26: Bellefo...
6
137.3 mi into trip | ~2h 34m in | I 99; US 220

Keep slight left at fork onto I 99; US 220 toward I 99 South, US 220 South: Port Matilda, Altoona

Highway fork - watch signs carefully. Multiple destination signs - pick the right one

Toward I 99 South, US 220 South: Port Matilda,...
8
247.1 mi into trip | ~4h 58m in | I 376; US 22 / Penn-Lincoln Parkway East

Keep slight right at fork onto I 376; US 22 / Penn-Lincoln Parkway East toward I 376 West, US 22 West: Pittsburgh

Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one

Use the slight left lane. Toward I 376 West, US 22 West: Pittsburgh
7
260.6 mi into trip | ~5h 16m in

Take the exit toward Second Avenue

Exit ramp - move to the correct lane early. Lane positioning matters here

Use the straight / slight right lanes. Exit 71B Toward Second Avenue
7
261.3 mi into trip | ~5h 18m in | Grant Street

Turn right onto Grant Street

Lane positioning matters here

Use the right lane.

Fuel & Cost

Regular Gas

$43.34 one way

$86.67 round trip

$4.21/gal 25.4 MPG avg 92 kg CO2
Fuel Type $/gal One Way Round Trip
midgrade $4.61 $47.46 $94.93
premium $4.93 $50.70 $101.39
diesel $5.61 $57.71 $115.43

No toll roads detected on this route.

Estimated Trip Cost (one way, 1 person)

Fuel

$43

Meals

$25–$50

Total

$68–$93

Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.

Estimated CO2 emission: 91.5 kg one way. Prices: EIA weekly data, 2026-04-13.

Driving Electric?

About $27 in charging · 0 stops · 66% less CO2

Vehicle Type kWh Stops DC Fast Home Charge
Average EV 78.4 0 $27.45 $12.55
Efficient EV 65.4 0 $22.87 $10.46
EV Truck/SUV 104.6 1 $36.60 $16.73

Gas CO2

91 kg

EV CO2

31 kg (66% less)

Plan for 0 charging stops, roughly every 270 miles. Allow 25-40 minutes per stop at a DC fast charger.

DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.

Travel Intel

Current conditions at both ends of the drive.

Forecast as of Apr 16, 2026

Origin

Middleburg, PA

Morning in Middleburg on Sunday

Local time

6:31 AM

EDT

Current temp

40°F

Unavailable

Live forecast

Destination

Pittsburgh, PA

Morning in Pittsburgh on Sunday

Local time

6:31 AM

EDT

Current temp

85°F

Chance Showers And Thunderstorms

SW 10 to 14 mph 48% chance Live forecast

Seasonal Notes

Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.

Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.

Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.

Time zone

Same local time

Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.

Temperature spread

45 degrees warmer at arrival

A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.

Road read

5h 18m on the road

An early start around 7-8 AM gets you there with plenty of daylight left.

Weather data from the National Weather Service. Conditions may change; check closer to your travel date.

What kind of drive is this?

Expect a 'turn-heavy local drive' profile for this 261.4-mile route. While 18% of your journey will be on highways, much of the 5-hour and 18-minute drive will involve navigating local roads and the Keystone Shortway. The longest uninterrupted stretch you'll encounter is 111.5 miles on the Keystone Shortway, offering a good period of consistent travel before more varied conditions return. This mix means you'll likely experience frequent changes in speed and road type, keeping you engaged behind the wheel.

Only 18% highway — the rest is turn-by-turn surface driving.
21 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 111.5 mi on Keystone Shortway.

How Hard Is This Drive?

7/10

Expect a hands-on drive with frequent turns and local roads rather than long highway stretches. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 112.8 miles in.

Driving Effort 7/10

Demanding - plan breaks and stay ahead of the key maneuvers

Balances navigation complexity with total wheel time.

This is a demanding drive. With 13 significant decision points across 261.4 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.

Where does it get tricky?

The main spots that need attention: at 112.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 137.3 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 247.1 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Towns Mentioned on Route Signs

Based on OSRM destination-sign hints, not a full list of every settlement the road passes.

Between Middleburg, PA and Pittsburgh, PA, road signs point toward Altoona and Hollidaysburg.

Altoona

137.3 mi in | ~2h 34m | via I 99; US 220

Hollidaysburg

171.1 mi in | ~3h 11m

About the Cities

Arriving in Pittsburgh, PA

Full guide →

The pleasure of Pittsburgh remains a well-kept secret. Though not built up by reputation, the city's unique combination of bridges, steep hills, and broad rivers make it one of the most naturally scenic cities in the country. Cheap food and beer abound in this true sports town and the locals are amazingly friendly. A city of about 303,000 (2021) in Allegheny County, at the center of a metro area of about 2.4 million in southwestern Pennsylvania, Pittsburgh is situated at the confluence of three rivers: the Monongahela and Allegheny Rivers, which meet to form the Ohio River. The city's unique terrain has resulted in an unusual city design and a hodge-podge of unique neighborhood "pockets" with diverse ethnic and architectural heritage.

City content from Wikivoyage (CC BY-SA 4.0) and Wikidata (CC0).

Who Is This Route For?

Weekend Trip

Doable as a same-day drive at 5h 18m. Total distance: 261.4 miles.

Family Friendly

Moderate complexity with 1 natural rest stops along the way.

Solo Traveler

5h 18m drive, comfortable solo distance.

Scenic Drive

Mostly surface roads route profile.

Frequently Asked Questions

The longest stretch is about 111.5 miles on Keystone Shortway. The full list of main roads is in the Roads section above.

We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.

It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Pittsburgh, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.

Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.

The main spots that need attention: at 112.8 miles: Exit ramp - move to the correct lane early. Multiple destination signs - pick the right one; at 137.3 miles (I 99; US 220): Highway fork - watch signs carefully. Multiple destination signs - pick the right one; at 247.1 miles (I 376; US 22 / Penn-Lincoln Parkway East): Highway fork - watch signs carefully. Lane positioning matters here. Multiple destination signs - pick the right one.

Not recommended in a single day. At 5.3 hours each way, a round trip means 10.6 hours of driving — that is an unsafe level of fatigue for most drivers. Plan at least one night at Pittsburgh, PA before the return drive.

How this page is built

Compiled by the US Trip Planner planning team at COD Solutions Oy from open government datasets — OSRM over OpenStreetMap for geometry, and EIA for fuel prices. See our methodology for refresh cadence and limitations.

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