Meyersdale, PA to Reading, PA is 207.3 miles and takes about 3h 59m via Pennsylvania Turnpike and US 222, with a fuel budget near $34 and enough daylight to finish in a day. This route stays within Pennsylvania, connecting two points in the Northeast region. With 91% of the drive on highways, expect a mostly straightforward trip. This is a feasible single-day drive, making it a good option if you're looking for an efficient way to cover ground between these two areas.
Trip Pace
Same-day drive is realistic
A same-day return is realistic if you keep stops short.
Break Rhythm
1 planned break
A short stop every 2 to 3 hours is enough for this drive.
Midpoint
103.7 miles from Meyersdale, PA
A natural place for your longest stop of the day
, about 1h 58m into the drive
.
Main Roads
Road
Distance
Duration
Pennsylvania Turnpike
176.8 mi
3h 14m
Flight 93 Memorial Highway
9.5 mi
10m
US 222
7.4 mi
9m
US 222 BUS
4.9 mi
8m
Berlin Plank Road
2.3 mi
3m
Mason Dixon Highway
1.6 mi
2m
Colonel Howard Boulevard
0.7 mi
1m
North Pleasant Avenue
0.6 mi
1m
Longest stretch:
Pennsylvania Turnpike
— 176.8 mi, about 3h 14m
Turn-by-Turn Driving Directions
Step-by-step road directions between Meyersdale, PA and Reading, PA.
1
Start on Meyers Avenue
365 ft·16 sec·Meyers Avenue
2
Turn right onto US 219 Business
0.5 mi·51 sec·Grant Street
3
Continue on US 219 Business
1.6 mi·2 min·Mason Dixon Highway
4
Take the ramp
0.6 mi·1 min
Toward US 219 North: Somerset
5
Merge onto US 219
9.5 mi·10 min·Flight 93 Memorial Highway
6
Take the exit
0.4 mi·50 sec
7
Turn left onto Berlin Plank Road
2.3 mi·3 min·Berlin Plank Road
Use the straight lane.
8
Continue on PA 31
0.4 mi·35 sec·East Main Street
9
Turn right onto PA 281
0.6 mi·1 min·North Pleasant Avenue
10
Continue on Ramada Road
0.3 mi·31 sec·Ramada Road
11
Take the ramp
0.2 mi·24 sec
Toward I 76 East, I 70 East: Harrisburg
12
Merge onto I 70; I 76; PATP
177 mi·3 hr 14 min·Pennsylvania Turnpike
13
Take the exit
0.2 mi·35 sec
Toward US 222: Reading, EphrataUse the slight right lane.
14
Continue on Colonel Howard Boulevard
0.6 mi·1 min·Colonel Howard Boulevard
15
Keep slight left at fork onto Colonel Howard Boulevard
0.1 mi·15 sec·Colonel Howard Boulevard
16
Keep slight right at fork
0.3 mi·35 sec
Toward US 222 North: Reading
17
Merge onto US 222
3.3 mi·3 min·US 222
18
Continue on US 222
4.1 mi·5 min·US 222
19
Take the exit onto US 222 BUS
4.9 mi·8 min·US 222 BUS
Toward US 222 Business: Lancaster Avenue, ShillingtonUse the slight right lane.
20
Turn left onto US 222 BUS
0.4 mi·47 sec·South 5th Street
Use the left lane.
21
Turn right onto US 422 Business
0.1 mi·16 sec·Franklin Street
22
Turn left onto South 6th Street
0.1 mi·24 sec·South 6th Street
Use the straight / left lanes.
23
Turn left onto US 422 Business Alternate
278 ft·4 sec·Penn Street
24
Arrive at destination
US 422 Business Alternate
Trip Plan
Given this is a trip under 4 hours, leaving anytime in the morning should allow you to arrive with plenty of daylight. The longest segment is a substantial 176.8 miles on the Pennsylvania Turnpike, so plan for your first break after that stretch. While the fuel cost is estimated at $34, it's always wise to start with a full tank. Consider stopping for a break around the halfway point if you prefer to split the driving more evenly, though it's not strictly necessary for a drive this duration.
Morning Departure
An early start around 7-8 AM gets you there with plenty of daylight left.
Evening Departure
A late afternoon start means arriving after dark. Morning is better.
You can normally do this drive in one day.
Plan roughly 1 meaningful break for fuel, food, and rest.
The halfway point lands around 103.7 miles from Meyersdale, PA, or about 1h 58m into the drive.
The longest continuous stretch on this route runs about 176.8 miles.
This is a comfortable same-day trip.
Departure
Before you leave
Start with fuel, water, and navigation already sorted so the first hour feels easy.
First stop
Around 46 miles or 55m in
Use this first pause for coffee, a restroom break, and a quick traffic check ahead.
Halfway reset
Around 103.7 miles or 1h 58m in
This is the best place for your longest stop, a real meal, and a full fuel check.
Final approach
Final hour starts around 3h 11m
Traffic, exits, and arrival timing usually matter more near Reading, PA than in the middle of the route.
Before You Leave
+
Open the route before leaving Meyersdale, PA so your first major turns are already loaded.
+
Leave with enough water and a charging cable within reach, not packed away.
+
Check your fuel range against the first long segment, especially if you are starting outside city service areas.
Day 1
Settle into the route from Meyersdale, PA
This is one driving day of about 207.3 miles and 3h 59m.
Your first comfortable stop window is around 46 miles from Meyersdale, PA.
This route can stay practical as a one-day drive if traffic stays reasonable.
Plan about 1 real break rather than only quick fuel stops.
The longest stretch is on Pennsylvania Turnpike for about 176.8 miles.
Where to Stop
Rest stops, refuel points, and overnight suggestions along this route.
Place data sourced from public business listings. Hours and availability may vary.
Heads-up: tricky spots
5 of 17
5 decision points cluster between mile 193.2 and 207.2 — GPS handles the exact turns, but know they're coming. Your lane choice matters more than the turn itself.
7
193.2 mi into trip|~3h 37m in
Take the exit toward US 222: Reading, Ephrata
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward US 222: Reading, Ephrata
6
194.1 mi into trip|~3h 39m in
Keep slight right at fork toward US 222 North: Reading
Highway fork - watch signs carefully
Toward US 222 North: Reading
7
201.7 mi into trip|~3h 49m in|US 222 BUS
Take the exit onto US 222 BUS toward US 222 Business: Lancaster Avenue, Shillington
Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one
Use the slight right lane.
Toward US 222 Business: Lancaster Avenue, Shill...
5
206.6 mi into trip|~3h 57m in|US 222 BUS / South 5th Street
Turn left onto US 222 BUS / South 5th Street
Lane positioning matters here
Use the left lane.
6
207.2 mi into trip|~3h 59m in|South 6th Street
Turn left onto South 6th Street
Lane positioning matters here
Use the straight / left lanes.
Fuel & Cost
Regular Gas
$36.20 one way
$72.41 round trip
$4.44/gal25.4 MPG avg73 kg CO2
Fuel Type
$/gal
One Way
Round Trip
midgrade
$4.86
$39.64
$79.28
premium
$5.20
$42.41
$84.81
diesel
$6.28
$51.22
$102.44
Estimated Tolls: $22.99
Pennsylvania Turnpike
(176.8 mi)$22.99
Toll estimates based on average 2024-2025 rates. EZ-Pass/SunPass discounts may lower the actual cost.
Estimated Trip Cost (one way, 1 person)
Fuel
$36
Tolls
$23
Meals
$25–$50
Total
$84–$109
Rough estimate based on US averages. Hotel $80–$140/night, meals $25–$50/day.
Estimated CO2 emission: 72.5 kg one way.
Prices: EIA weekly data, 2026-10-19.
Driving Electric?
About $22 in charging
· 0 stops
· 67% less CO2
Vehicle Type
kWh
Stops
DC Fast
Home Charge
Average EV
62.2
0
$21.77
$9.95
Efficient EV
51.8
0
$18.14
$8.29
EV Truck/SUV
82.9
1
$29.02
$13.27
Gas CO2
73 kg
EV CO2
24 kg (67% less)
This trip is well within single-charge range for most EVs. No charging stops needed if you start fully charged.
DC fast charging avg $0.35/kWh. Home charging avg $0.16/kWh. US grid CO2: 0.39 kg/kWh.
Travel Intel
Current conditions at both ends of the drive.
Forecast as of Oct 19, 2026
Origin
Meyersdale, PA
Morning
in Meyersdale on Saturday
Local time
8:16 AM
EDT
Current temp
64°F
Sunny
NE 0 to 3 mph0% chanceLive forecast
Destination
Reading, PA
Morning
in Reading on Saturday
Local time
8:16 AM
EDT
Current temp
66°F
Widespread Frost then Sunny
N 0 to 5 mph0% chanceLive forecast
Seasonal Notes
Summer travel usually means heavier construction, hotter rest stops, and busier weekend traffic around major cities.
Winter travel shortens daylight, so a route that looks manageable on paper can feel much longer after dark.
Holiday weekends tend to make both departure and arrival windows slower than the raw route time suggests.
Time zone
Same local time
Origin and destination are on the same clock, so arrival timing is easier to judge at a glance.
Temperature spread
2 degrees warmer at arrival
A meaningful temperature swing is a good cue to rethink layers, water, and how soon you want to arrive.
Road read
3h 59m on the road
The weather snapshot is not static. If you are leaving later, give both cities one more quick forecast check before departure.
Weather data from the National Weather Service. Conditions may change; check closer to your travel date.
National Parks Near This Route
Worth a detour if your schedule allows.
Carlisle Federal Indian Boarding School National Monument
National Monument
More than 7,800 children from 140 Tribes went to the Carlisle School from 1879 to 1918. The National Park Service will collaborate with families, affiliated Tribal Nations, the US Army, historians, an...
3 mi from route
~8 min detour
Free
near mile 128.7
On Tuesday morning, September 11, 2001, the U.S. came under attack when four commercial airliners were hijacked and used to strike targets on the ground. Nearly 3,000 people tragically lost their live...
7 mi from route
~17 min detour
Free
near mile 28.6
The Appalachian Trail is a 2,190+ mile long public footpath that traverses the scenic, wooded, pastoral, wild, and culturally resonant lands of the Appalachian Mountains. Conceived in 1921, built by p...
13 mi from route
~32 min detour
Free
near mile 171.6
The South Fork Dam failed on Friday, May 31, 1889, and unleashed 20,000,000 tons of water that devastated Johnstown, PA. The flood killed 2,209 people but it brought the nation and the world together...
The battle at Fort Necessity in the summer of 1754 was the opening action of the French and Indian War. This war was a clash of British, French and American Indian cultures. It ended with the removal...
29 mi from route
~74 min detour
Free
near mile 7.1
Park data from the National Park Service API. Alerts update every 2 hours.
More Details
What kind of drive is this?
This drive is predominantly highway, with 91% of the 207.3 miles on high-speed roads. You'll spend the longest stretch, 176.8 miles, on the Pennsylvania Turnpike. After that, you'll transition to surface roads, likely noticing a change in traffic density and exit frequency as you approach Reading on US 222.
91% highway — fuel and pacing are the main things to plan.
24 navigation steps total — most of the decisions cluster near the start and finish.
Longest single stretch: 176.8 mi on Pennsylvania Turnpike.
How Hard Is This Drive?
7/10
This is a straightforward highway drive that stays mostly on Pennsylvania Turnpike and Flight 93 Memorial Highway. This route has several spots where lane changes, forks, or exits need your full attention. The trickiest moment comes around 193.2 miles in.
Driving Effort7/10
Demanding - plan breaks and stay ahead of the key maneuvers
Balances navigation complexity with total wheel time.
This is a demanding drive. With 17 significant decision points across 207.3 miles, you will need to stay alert - especially through interchange areas and urban stretches. Consider splitting it into segments if you are not comfortable with fast highway navigation.
Where does it get tricky?
The main spots that need attention: at 193.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 194.1 miles: Highway fork - watch signs carefully; at 201.7 miles (US 222 BUS): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Elevation Profile
Gently rolling terrain
2,432 ft253 ft
Total Climb
588 ft
Total Descent
2,323 ft
Highest Point
2,432 ft
~29.6 mi in
Elevation Range
2,179 ft
Towns Mentioned on Route Signs
Based on OSRM destination-sign hints, not a full list of every settlement the road passes.
On the drive from Meyersdale, PA to Reading, PA, road signs begin pointing toward Ephrata along the way.
Reading is a historic city of about 95,000 (2020 Census) in Pennsylvania, about 50 miles northwest of Philadelphia, 35 miles southwest of Allentown and 55 miles east of Harrisburg. It punches above its weight in culture, and its downtown features some iconic buildings, so consider making it a stopover on your way between any of these and other area cities.
Top landmarks
•Frederick Lauer Monument — monument in City Park, Reading, Pennsylvania, United States
Doable as a same-day drive at 3h 59m. Total distance: 207.3 miles.
Family Friendly
Moderate complexity with 1 natural rest stops along the way.
Solo Traveler
3h 59m drive, comfortable solo distance.
First-Time Driver
Mostly highway driving (91%). Some complex stretches to watch for.
Frequently Asked Questions
The longest stretch is about 176.8 miles on Pennsylvania Turnpike. The full list of main roads is in the Roads section above.
Expect about $22.99 in tolls one way, starting with Pennsylvania Turnpike. Most Northeast and Midwest toll agencies accept E-ZPass; in the West and Texas, transponders like TxTag or FasTrak apply. If you do not have a transponder, cashless tolling plates will mail a bill to the vehicle's registered address — usually with a surcharge, so a rental-car toll pass is often cheaper than paying by mail.
We did not find dedicated rest areas on this route. For a drive this long, plan bathroom and stretch breaks around gas stations, fast-food stops, or small-town downtowns — check the Nearby Places section for options.
It helps. This route has a higher-than-average number of complex decision points, which get harder in the dark. If the last hour of the trip is on surface roads or mountain grades, aim to arrive at Reading, PA before sunset when you can. Check the Trip Plan for departure windows that land you in daylight.
Only with planning. This is a long drive for kids — consider splitting it into two days rather than pushing through. Plan at least 1 meaningful breaks. Dedicated rest areas are limited, so plan gas or food stops as your bathroom breaks.
The main spots that need attention: at 193.2 miles: Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one; at 194.1 miles: Highway fork - watch signs carefully; at 201.7 miles (US 222 BUS): Exit ramp - move to the correct lane early. Lane positioning matters here. Multiple destination signs - pick the right one.
Yes — Carlisle Federal Indian Boarding School National Monument, Flight 93 National Memorial and Appalachian National Scenic Trail (5 total within detour distance). See the National Parks section for detour distances and tips on detours.
Possible but tiring. At 4.0 hours each way, an in-and-out day trip would put you behind the wheel for 8.0 hours — manageable with a long break at Reading, PA, but most travelers stay overnight.
